Senior AI Product Manager Jobs in Massachusetts

Senior AI Product Manager jobs in Massachusetts are among the most actively sought roles in the country, concentrated in life sciences technology, enterprise software, and financial services firms that have made Boston and Cambridge global centers for AI-driven product development. Most hiring is in Boston, Cambridge, and the Route 128 corridor, where employers like HubSpot, Wayfair, and athenahealth maintain large product and engineering organizations. The most in-demand specializations are healthcare AI, autonomous systems, and large language model product strategy. Find a role that fits below and apply directly.

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Overview

Open roles50
Top employerAmazon
Top cityBoston, MA
Cities hiring12
Work type48% Hybrid
Top industryTechnology

Showing 5 of 50+ Senior AI Product Manager jobs

Amazon.com
Applied Science Manager, Artificial General Intelligence , Frontier AI Assets: Assessments
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Amazon.com
Added 1d ago
Applied Science Manager, Artificial General Intelligence , Frontier AI Assets: Assessments
Amazon.com
Boston, Massachusetts
Business Strategy
Project Management
Strategy & Corporate Development
$184k - $249k/yr
10,000+

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Amazon.com
Applied Scientist, Artificial General Intelligence, Frontier AI
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Amazon.com
Added 2d ago
Applied Scientist, Artificial General Intelligence, Frontier AI
Amazon.com
Boston, Massachusetts
Business Operations
Compensation & Benefits
Human Resources (HR) — Generalist
$136k - $184k/yr
Master's degree
10,000+

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Evolv Technologies
Director of Product, AI
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Evolv Technologies
Added 6d ago
Director of Product, AI
Evolv Technologies
Waltham, Massachusetts
Quality Assurance & Testing (QA Testing)
Software Engineering
Technical Product & Program Management
$162k - $258k/yr
Hybrid

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athenahealth
Senior Product Manager - AI Trust & Transparency
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athenahealth
Added 1w ago
Senior Product Manager - AI Trust & Transparency
athenahealth
Boston, Massachusetts
Project Management
Solutions Engineering & Architecture
Technical Program Management
$141k - $239k/yr
Hybrid
5,001-10,000

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American Heart Association
Business Development Lead, Clinical Product & Platforms, American Heart Association AI TORCH
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American Heart Association
Added 1w ago
Business Development Lead, Clinical Product & Platforms, American Heart Association AI TORCH
American Heart Association
Boston, Massachusetts
Business Operations
Compensation & Benefits
Human Resources (HR) — Generalist
$135k - $145k/yr
Remote (US)
Bachelor's degree
1,001-5,000

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See All 50 Senior AI Product Manager Jobs in Massachusetts

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Senior AI Product Manager Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Boston
31 jobs
Waltham
4 jobs
Cambridge
4 jobs
Burlington
2 jobs
Andover
1 job
Hingham
1 job
Needham
1 job
Peabody
1 job
Reading
1 job

Senior AI Product Manager Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Amazon
Amazon5 open roles
State Street
State Street3 open roles
Whoop
Whoop2 open roles

Top Industries Hiring

  • Technology & Software
  • Insurance
  • Healthcare & Medical Services
  • Biotechnology & Pharmaceuticals
  • Law & Legal Services

What Massachusetts Employers Look For

The qualifications that appear most often in senior AI product manager jobs across Massachusetts.

  • Bachelor's or master's degree in computer science, engineering, or a related technical field
  • Five or more years of product management experience with at least two in AI or machine learning products
  • Demonstrated ability to define and ship AI-powered product features from discovery through launch
  • Strong cross-functional collaboration with data science, engineering, and UX teams
  • Experience with agile development methodologies and product lifecycle tools such as Jira or Productboard
  • Familiarity with responsible AI principles, data privacy regulations, and model governance practices

Senior AI Product Manager Jobs in Massachusetts: Frequently Asked Questions

How do you become a senior ai product manager in Massachusetts?

The typical path in Massachusetts starts with a technical degree followed by several years in product management, often in software, data, or analytics roles. There is no state-issued license required for this role. Massachusetts employers, particularly in the Boston and Cambridge life sciences and enterprise software clusters, expect candidates to have hands-on AI product experience, a portfolio of shipped ML-adjacent features, and familiarity with regulated data environments common in healthcare and fintech.

Which companies hire senior ai product managers in Massachusetts?

Employers hiring senior ai product managers in Massachusetts right now include Amazon, State Street, and Whoop, based on current listings on Migrate Mate as of September 2026. Massachusetts's concentration of biotech, health IT, and enterprise software firms means demand tends to be consistent year-round rather than tied to a single hiring season.

Which Massachusetts cities have the most senior ai product manager jobs?

Boston, Waltham, and Cambridge have the most senior ai product manager openings in Massachusetts. Boston and Cambridge drive the bulk of demand through their dense clusters of AI startups, university-affiliated research spinouts, and major enterprise technology headquarters, while suburban Route 128 corridor cities attract openings from legacy software and life sciences firms that have built substantial product teams outside the urban core.

Are there remote senior ai product manager jobs in Massachusetts?

Yes, and more than most fields. About 61% of senior ai product manager openings tied to Massachusetts are remote or hybrid as of September 2026, reflecting how central collaboration tools and async workflows have become in product organizations. The parts of the role most often performed remotely are roadmap planning, stakeholder alignment, and cross-functional coordination, while onsite presence is more common during product discovery sprints or executive reviews.

How can I get hired as a senior ai product manager in Massachusetts with little or no experience?

The most realistic entry path is moving laterally from a technical or analytical role, such as data analyst, software engineer, or business systems analyst, into an associate or junior product manager position. Large Massachusetts employers like MathWorks, Veeva Systems, and major Boston hospital systems run rotational or associate PM programs that accept candidates transitioning from adjacent roles. Building a portfolio that demonstrates AI product thinking, including documented experiments, metric-driven decisions, or open-source contributions, gives candidates a concrete edge when experience is limited.

Where can I find and apply to senior ai product manager jobs in Massachusetts?

You can find and apply to senior ai product manager jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings updated regularly. Search the listings, find roles that match your background and preferences, and apply directly to the ones that fit.

See All 50 Senior AI Product Manager Jobs in Massachusetts

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