Senior AI Product Manager Jobs in Massachusetts
Senior AI Product Manager jobs in Massachusetts are among the most actively sought roles in the country, concentrated in life sciences technology, enterprise software, and financial services firms that have made Boston and Cambridge global centers for AI-driven product development. Most hiring is in Boston, Cambridge, and the Route 128 corridor, where employers like HubSpot, Wayfair, and athenahealth maintain large product and engineering organizations. The most in-demand specializations are healthcare AI, autonomous systems, and large language model product strategy. Find a role that fits below and apply directly.
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DESCRIPTION
The Artificial General Intelligence (AGI) team is seeking a dedicated, skilled, and innovative Applied Science Manager with a robust background in machine learning, statistics, quality assurance, auditing methodologies, and automated evaluation systems to lead a team ensuring the highest standards of data quality, to build industry-leading technology with Large Language Models (LLMs) and multimodal systems.
Key job responsibilities
As part of the AGI team, an Applied Science Manager will lead and mentor a team of Applied Scientists who develop comprehensive quality strategies and auditing frameworks that safeguard the integrity of data collection workflows. The manager will guide the team in designing auditing strategies with detailed SOPs, quality metrics, and sampling methodologies that align with core scientist team developing Amazon Nova models. The Applied Science Manager will oversee expert-level manual audits, meta-audits to evaluate auditor performance, and provide coaching to uplift overall quality capabilities across the team. A critical aspect of this role involves managing the development and maintenance of LLM-as-a-Judge systems, including designing judge architectures, creating evaluation rubrics, and building machine learning models for automated quality assessment. The Applied Science Manager will also oversee the configuration of data collection workflows and ensure effective communication of quality feedback to stakeholders. The manager will have a direct impact on enhancing customer experiences through high-quality training and evaluation data that powers state-of-the-art LLM products and services.
The Applied Science Manager will be responsible for recruiting, hiring, and developing team members, conducting performance reviews, setting clear expectations and growth plans, and fostering a culture of scientific excellence and innovation. The manager will communicate with senior leadership, cross-functional technical teams, and customers to collect requirements, describe product features and technical designs, and articulate product strategy.
A day in the life
An Applied Science Manager with the AGI team will lead quality solution design, guide root cause analysis on data quality issues, drive research into new auditing methodologies, and find innovative ways of optimizing data quality while setting examples for the team on quality assurance best practices and standards. The manager will work closely with talented engineers, domain experts, and vendor teams to put quality strategies and automated judging systems into practice. The manager will also conduct regular 1:1s with team members, provide mentorship and coaching, and ensure the team delivers high-impact results aligned with organizational goals.
BASIC QUALIFICATIONS
- 3+ years of scientists or machine learning engineers management experience
- Knowledge of ML, NLP, Information Retrieval and Analytics
PREFERRED QUALIFICATIONS
- Experience building machine learning models or developing algorithms for business application
- Experience building complex software systems, especially involving deep learning, machine learning and computer vision, that have been successfully delivered to customers
Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.
Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit https://amazon.jobs/content/en/how-we-hire/accommodations for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.
The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.
USA, MA, Boston - 183,800.00 - 248,700.00 USD annually
USA, WA, BELLEVUE - 183,800.00 - 248,700.00 USD annually
See All 50 Senior AI Product Manager Jobs in Massachusetts
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Find JobsSenior AI Product Manager Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Senior AI Product Manager Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Technology & Software
- Insurance
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
- Law & Legal Services
What Massachusetts Employers Look For
The qualifications that appear most often in senior AI product manager jobs across Massachusetts.
- Bachelor's or master's degree in computer science, engineering, or a related technical field
- Five or more years of product management experience with at least two in AI or machine learning products
- Demonstrated ability to define and ship AI-powered product features from discovery through launch
- Strong cross-functional collaboration with data science, engineering, and UX teams
- Experience with agile development methodologies and product lifecycle tools such as Jira or Productboard
- Familiarity with responsible AI principles, data privacy regulations, and model governance practices
Senior AI Product Manager Jobs in Massachusetts: Frequently Asked Questions
How do you become a senior ai product manager in Massachusetts?
The typical path in Massachusetts starts with a technical degree followed by several years in product management, often in software, data, or analytics roles. There is no state-issued license required for this role. Massachusetts employers, particularly in the Boston and Cambridge life sciences and enterprise software clusters, expect candidates to have hands-on AI product experience, a portfolio of shipped ML-adjacent features, and familiarity with regulated data environments common in healthcare and fintech.
Which companies hire senior ai product managers in Massachusetts?
Employers hiring senior ai product managers in Massachusetts right now include Amazon, State Street, and Whoop, based on current listings on Migrate Mate as of September 2026. Massachusetts's concentration of biotech, health IT, and enterprise software firms means demand tends to be consistent year-round rather than tied to a single hiring season.
Which Massachusetts cities have the most senior ai product manager jobs?
Boston, Waltham, and Cambridge have the most senior ai product manager openings in Massachusetts. Boston and Cambridge drive the bulk of demand through their dense clusters of AI startups, university-affiliated research spinouts, and major enterprise technology headquarters, while suburban Route 128 corridor cities attract openings from legacy software and life sciences firms that have built substantial product teams outside the urban core.
Are there remote senior ai product manager jobs in Massachusetts?
Yes, and more than most fields. About 61% of senior ai product manager openings tied to Massachusetts are remote or hybrid as of September 2026, reflecting how central collaboration tools and async workflows have become in product organizations. The parts of the role most often performed remotely are roadmap planning, stakeholder alignment, and cross-functional coordination, while onsite presence is more common during product discovery sprints or executive reviews.
How can I get hired as a senior ai product manager in Massachusetts with little or no experience?
The most realistic entry path is moving laterally from a technical or analytical role, such as data analyst, software engineer, or business systems analyst, into an associate or junior product manager position. Large Massachusetts employers like MathWorks, Veeva Systems, and major Boston hospital systems run rotational or associate PM programs that accept candidates transitioning from adjacent roles. Building a portfolio that demonstrates AI product thinking, including documented experiments, metric-driven decisions, or open-source contributions, gives candidates a concrete edge when experience is limited.
Where can I find and apply to senior ai product manager jobs in Massachusetts?
You can find and apply to senior ai product manager jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings updated regularly. Search the listings, find roles that match your background and preferences, and apply directly to the ones that fit.
See All 50 Senior AI Product Manager Jobs in Massachusetts
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