Senior AI Software Engineer Jobs in Pennsylvania
Senior AI Software Engineer jobs in Pennsylvania are in strong demand, with the market concentrated in enterprise technology, financial services, healthcare IT, and defense contracting, and openings at every experience level from associate to principal. Philadelphia, Pittsburgh, and Malvern are the leading hiring hubs, home to major employers such as Comcast, SAP, and Lockheed Martin that maintain deep AI and machine learning teams in the state. The most sought-after specialties include large language model development, MLOps infrastructure, and AI systems integration for regulated industries. Find a role that fits below and apply directly.
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The Expert Software Engineer is responsible for managing cloud infrastructure, deployment automation, testing frameworks, observability, security controls, and release management across AI-enabled application environments. The AI Expert DevOps Engineer will own the platform engineering foundation behind Jefferson's Azure-hosted AI Factory — enabling faster, safer, and more reliable delivery of AI-generated and AI-assisted applications at enterprise scale.Job Description
Summary
The Expert Software Engineer is responsible for managing cloud infrastructure, deployment automation, testing frameworks, observability, security controls, and release management across AI-enabled application environments. The AI Expert DevOps Engineer will own the platform engineering foundation behind Jefferson's Azure-hosted AI Factory — enabling faster, safer, and more reliable delivery of AI-generated and AI-assisted applications at enterprise scale.
Job Duties
- Manage Azure-hosted AI Factory environments and related software solutions
- Build and maintain deployment pipelines supporting AI-assisted development
- Automate testing, release validation, and governance controls
- Implement monitoring, observability, operational intelligence, and incident response capabilities
- Manage containerization, CI/CD pipelines, infrastructure as code, and platform automation
- Support integration with enterprise AI platforms, development environments, and cloud services
- Ensure enterprise security, compliance, availability, resiliency, and scalability standards are maintained
- Establish and maintain platform engineering standards, deployment patterns, and operational best practices for AI-generated applications
- Optimize cloud resource utilization, platform performance, and operational costs across AI Factory environments
- Implement disaster recovery, business continuity, backup, and high-availability capabilities for critical AI services
- Collaborate with Architecture, Security, Infrastructure, and Development teams to enable secure, scalable AI software delivery
- Evaluate and adopt emerging DevOps, automation, and cloud engineering capabilities that improve software delivery effectiveness
Minimum Qualifications
- Bachelor’s Degree in Computer Science, Engineering, or related field or
- High School Diploma/GED and 10 years preferred work experience.
- 7 years in software development, including experience with distributed systems and cloud platforms.
- Strong hands-on experience with Microsoft Azure cloud infrastructure and services
- Experience building and maintaining CI/CD pipelines and deployment automation for enterprise applications
- Experience with infrastructure as code (e.g., Terraform, Bicep, ARM templates) and containerization (e.g., Docker, Kubernetes)
- Experience implementing monitoring, observability, and incident response tooling for production environments
- Demonstrated ownership of platform security, compliance, availability, and resiliency practices
- Track record of operating and scaling cloud platforms in a senior/expert capacity, including disaster recovery and business continuity planning
- Roughly 5+ years of relevant DevOps/platform/cloud engineering experience, or equivalent depth — exact tenure matters less than demonstrated ownership of complex, production-scale cloud platforms
Preferred Qualifications
- Master’s Degree in Computer Science, Engineering, or related field
- 10 years with a track record of solving complex technical challenges and mentoring engineers.
- Experience supporting AI-assisted or AI-generated software delivery environments specifically
- Experience integrating DevOps pipelines with enterprise AI platforms or AI development tooling
- Healthcare or other regulated-industry background
- Relevant certifications (Azure, Kubernetes, DevOps/SRE-related)
- Experience establishing platform engineering standards or self-service developer platforms across multiple teams
- Experience optimizing cloud cost/utilization at scale
Physical Demands
Lift and carry 25 lbs. frequent sitting/standing, frequent keyboard use, *patient care providers may be required to perform activities specific to their role including kneeling, bending, squatting and performing CPR.
Job Description Disclaimer: This position description provides the major duties/responsibilities, requirements and working conditions for the position. It is intended to be an accurate reflection of the current position, however management reserves the right to revise or change as necessary to meet organizational needs. Other responsibilities may be assigned when circumstances require.
Work Shift
Workday Day (United States of America)Worker Sub Type
RegularEmployee Entity
Primary Location Address
1100 Virginia Drive, Fort Washington, Pennsylvania, United States of AmericaNationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research. Thomas Jefferson University , home of Sidney Kimmel Medical College, Jefferson College of Nursing, and the Kanbar College of Design, Engineering and Commerce, dates back to 1824 and today comprises 10 colleges and three schools offering 200+ undergraduate and graduate programs to more than 8,300 students. Jefferson Health , nationally ranked as one of the top 15 not-for-profit health care systems in the country and the largest provider in the Philadelphia and Lehigh Valley areas, serves patients through millions of encounters each year at 32 hospitals campuses and more than 700 outpatient and urgent care locations throughout the region. Jefferson Health Plans is a not-for-profit managed health care organization providing a broad range of health coverage options in Pennsylvania and New Jersey for more than 35 years.
Jefferson is committed to providing equal educational and employment opportunities for all persons without regard to age, race, color, religion, creed, sexual orientation, gender, gender identity, marital status, pregnancy, national origin, ancestry, citizenship, military status, veteran status, handicap or disability or any other protected group or status.
Benefits
Jefferson offers a comprehensive package of benefits for full-time and part-time colleagues, including medical (including prescription), supplemental insurance, dental, vision, life and AD&D insurance, short- and long-term disability, flexible spending accounts, retirement plans, tuition assistance, as well as voluntary benefits, which provide colleagues with access to group rates on insurance and discounts. Colleagues have access to tuition discounts at Thomas Jefferson University after one year of full time service or two years of part time service. All colleagues, including those who work less than part-time (including per diem colleagues, adjunct faculty, and Jeff Temps ), have access to medical (including prescription) insurance.
See All 34 Senior AI Software Engineer Jobs in Pennsylvania
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Where Pennsylvania roles are concentrated, by current openings.
Senior AI Software Engineer Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Education
- Technology & Software
- Food & Beverage
- Transportation & Logistics
- Banking & Financial Services
What Pennsylvania Employers Look For
The qualifications that appear most often in senior AI software engineer jobs across Pennsylvania.
- Bachelor's or master's degree in computer science, AI, or a closely related engineering field
- Proven experience designing and deploying production-grade machine learning or deep learning systems
- Strong proficiency in Python and familiarity with frameworks such as PyTorch or TensorFlow
- Experience with cloud platforms including AWS, Azure, or Google Cloud for AI workloads
- Ability to lead cross-functional teams and mentor junior engineers on AI best practices
- Familiarity with MLOps pipelines, model monitoring, and responsible AI or compliance requirements
Senior AI Software Engineer Jobs in Pennsylvania: Frequently Asked Questions
How do you become a senior ai software engineer in Pennsylvania?
There is no state-issued license required to work as a senior ai software engineer in Pennsylvania. The typical path starts with a bachelor's degree in computer science, software engineering, or a related field, followed by hands-on experience building and shipping AI or machine learning systems. Pennsylvania employers, particularly in Philadelphia's fintech corridor and Pittsburgh's robotics and autonomous systems community, strongly favor candidates who can show production deployments and a portfolio of real-world model work alongside their formal credentials.
How much do senior AI software engineers make in Pennsylvania?
Senior AI software engineers in Pennsylvania earn a median of about $126,550 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $77,750 for the lowest 10% to over $178,080 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior ai software engineers in Pennsylvania?
Employers hiring senior ai software engineers in Pennsylvania right now include Penn State University, Carnegie Mellon University, and Google, based on current listings on Migrate Mate as of September 2026. Pennsylvania's mix of large enterprise technology firms, health systems, and defense contractors means demand is spread across multiple industries rather than concentrated in a single sector.
Which Pennsylvania cities have the most senior ai software engineer jobs?
Pittsburgh, Philadelphia, and University Park are the Pennsylvania cities with the most senior ai software engineer openings. Philadelphia anchors the market through its concentration of financial services firms, health systems, and major tech employers, while Pittsburgh draws heavily from its robotics research ecosystem and strong ties to Carnegie Mellon University, and suburban corridors like Malvern attract demand from enterprise software companies headquartered along the Route 30 technology belt.
Are there remote senior ai software engineer jobs in Pennsylvania?
Yes, and more than most fields. About 43% of senior ai software engineer openings tied to Pennsylvania are remote or hybrid as of September 2026, reflecting how well AI development work travels outside a physical office. Model research, experimentation, and code review lend themselves especially well to fully remote arrangements, though roles involving proprietary data in regulated industries such as defense or healthcare often require at least partial on-site presence.
How can I get hired as a senior ai software engineer in Pennsylvania with little or no experience?
The most realistic entry path is building a demonstrated project portfolio while targeting associate or junior AI engineer roles that large Pennsylvania employers use as a pipeline for senior talent. Companies like Comcast and SAP in the Philadelphia area run technology associate programs that accept candidates from new-grad backgrounds. Lateral moves from software engineering, data science, or data engineering positions are common and well-recognized in Pennsylvania hiring. Completing a recognized ML certification and contributing to open-source AI projects strengthens a profile considerably for competitive Pennsylvania employers.
Where can I find and apply to senior ai software engineer jobs in Pennsylvania?
You can find and apply to senior ai software engineer jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings updated regularly. Search the listings to see what is available across the state, find roles that match your background and goals, and apply directly to the ones that fit.
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