Staff Software Developer Jobs in Pennsylvania
Staff Software Developer jobs in Pennsylvania are in strong demand, with active hiring concentrated in enterprise software, financial services, healthcare IT, and defense contracting at levels from mid-career engineers through principal contributors. Philadelphia, Pittsburgh, and the suburban Philadelphia corridor anchor most of the hiring activity, where established names like Comcast, UPMC, and Lockheed Martin maintain large engineering organizations. The most sought-after specializations in Pennsylvania are cloud-native backend development, distributed systems, and full-stack engineering for regulated industries. Find a role that fits below and apply directly.
Find Staff Software Developer JobsOverview
Showing 5 of 20+ Staff Software Developer jobs
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
We are seeking a Senior Staff Software Engineer to help architect and build the data platform and backend services for our healthcare SaaS solutions. This is a hands-on technical leadership role requiring deep expertise in database and data architecture, cloud-native backend development, scalability, security, and healthcare interoperability.
The ideal candidate combines strong software engineering skills with the ability to design secure, high-performance data architectures for large-scale, multi-tenant applications handling sensitive healthcare data.
Key Responsibilities
- Architect and develop scalable backend services and data platforms for multi-tenant SaaS applications.
- Design and optimize relational and non-relational database architectures, data models, and storage strategies.
- Build scalable data ingestion, integration, and processing capabilities for large and complex healthcare datasets.
- Design cloud-native data architectures incorporating databases, data lakes/lakehouses, and distributed data platforms.
- Develop APIs and integration capabilities supporting healthcare interoperability, including HL7 and FHIR.
- Ensure appropriate architecture for security, encryption, access control, auditability, data governance, retention, and regulatory compliance.
- Design for high availability, disaster recovery, performance, and scalability.
- Provide technical leadership and architectural guidance while remaining hands-on with design and development.
- Collaborate with Software Engineering, Product, Security, Quality, and Regulatory teams.
Required Qualifications
- Bachelor’s or Master’s degree in Computer Science, Engineering, Information Systems, or related field.
- 10+ years of software engineering experience, including significant backend and data-platform development.
- Deep experience designing and optimizing relational databases such as PostgreSQL, SQL Server, or MySQL.
- Experience with NoSQL technologies such as MongoDB, Cosmos DB, or equivalent.
- Strong experience with cloud platforms (Azure, AWS, or GCP) and cloud-native architectures.
- Experience with modern data pipelines, ingestion frameworks, data lakes/lakehouses, and distributed data architectures.
- Strong understanding of multi-tenant SaaS architecture, APIs, scalability, security, and data governance.
- Experience designing systems that handle sensitive or regulated data.
Preferred Qualifications
- Healthcare software or regulated-industry experience.
- Experience with HL7, FHIR, EHR/EMR integration, or healthcare interoperability.
- Experience with Databricks, Azure Data Factory, Kafka, Spark, or similar technologies.
- Experience with containerized environments such as Docker and Kubernetes.
Compensation and Benefits
The salary range estimated for this position based in Indiana is $135,800.00–$203,750.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
We are seeking a Senior Staff Software Engineer to help architect and build the data platform and backend services for our healthcare SaaS solutions. This is a hands-on technical leadership role requiring deep expertise in database and data architecture, cloud-native backend development, scalability, security, and healthcare interoperability.
The ideal candidate combines strong software engineering skills with the ability to design secure, high-performance data architectures for large-scale, multi-tenant applications handling sensitive healthcare data.
Key Responsibilities
- Architect and develop scalable backend services and data platforms for multi-tenant SaaS applications.
- Design and optimize relational and non-relational database architectures, data models, and storage strategies.
- Build scalable data ingestion, integration, and processing capabilities for large and complex healthcare datasets.
- Design cloud-native data architectures incorporating databases, data lakes/lakehouses, and distributed data platforms.
- Develop APIs and integration capabilities supporting healthcare interoperability, including HL7 and FHIR.
- Ensure appropriate architecture for security, encryption, access control, auditability, data governance, retention, and regulatory compliance.
- Design for high availability, disaster recovery, performance, and scalability.
- Provide technical leadership and architectural guidance while remaining hands-on with design and development.
- Collaborate with Software Engineering, Product, Security, Quality, and Regulatory teams.
Required Qualifications
- Bachelor’s or Master’s degree in Computer Science, Engineering, Information Systems, or related field.
- 10+ years of software engineering experience, including significant backend and data-platform development.
- Deep experience designing and optimizing relational databases such as PostgreSQL, SQL Server, or MySQL.
- Experience with NoSQL technologies such as MongoDB, Cosmos DB, or equivalent.
- Strong experience with cloud platforms (Azure, AWS, or GCP) and cloud-native architectures.
- Experience with modern data pipelines, ingestion frameworks, data lakes/lakehouses, and distributed data architectures.
- Strong understanding of multi-tenant SaaS architecture, APIs, scalability, security, and data governance.
- Experience designing systems that handle sensitive or regulated data.
Preferred Qualifications
- Healthcare software or regulated-industry experience.
- Experience with HL7, FHIR, EHR/EMR integration, or healthcare interoperability.
- Experience with Databricks, Azure Data Factory, Kafka, Spark, or similar technologies.
- Experience with containerized environments such as Docker and Kubernetes.
Compensation and Benefits
The salary range estimated for this position based in Indiana is $135,800.00–$203,750.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
See All 20 Staff Software Developer Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Staff Software Developer JobsStaff Software Developer Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Staff Software Developer Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Science & Research
- Retail
What Pennsylvania Employers Look For
The qualifications that appear most often in staff software developer jobs across Pennsylvania.
- Bachelor's or master's degree in computer science, software engineering, or a closely related field
- Five or more years of professional software development experience in production environments
- Deep proficiency in at least one primary language such as Java, Python, Go, or C++
- Demonstrated experience designing and owning large-scale distributed systems or microservices architectures
- Strong collaboration skills working across cross-functional teams including product, QA, and platform engineering
- Experience with cloud platforms such as AWS, Azure, or Google Cloud and modern CI/CD tooling
Staff Software Developer Jobs in Pennsylvania: Frequently Asked Questions
How do you become a staff software developer in Pennsylvania?
Software development carries no Pennsylvania state license or board registration, so the path runs through education and demonstrated experience. Most Pennsylvania employers at the staff level expect a bachelor's degree in computer science or a related field plus several years of progressive engineering work. Building a portfolio of substantial open-source or production projects, contributing to recognized codebases, and earning cloud certifications recognized by major Pennsylvania employers all strengthen a candidacy meaningfully.
How much do staff software developers make in Pennsylvania?
Staff software developers in Pennsylvania earn a median of about $126,550 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $77,750 for the lowest 10% to over $178,080 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire staff software developers in Pennsylvania?
Employers hiring staff software developers in Pennsylvania right now include Stack AV, CVS Health, and Ghost Robotics, based on current listings on Migrate Mate as of November 2026. Pennsylvania's concentration of healthcare systems, defense contractors, and financial services firms means steady engineering demand that persists across broader hiring cycles.
Which Pennsylvania cities have the most staff software developer jobs?
Pittsburgh, Pennsylvania, and Philadelphia lead Pennsylvania for staff software developer openings. Philadelphia drives volume through its large financial services, pharmaceutical, and media technology employers, Pittsburgh has become a recognized engineering hub anchored by Carnegie Mellon's research ecosystem and a growing robotics and AI cluster, and suburban Philadelphia communities like Malvern and Wayne host major enterprise software and defense technology campuses that generate consistent senior engineering demand.
Are there remote staff software developer jobs in Pennsylvania?
Yes, and more than most fields. About 86% of staff software developer openings tied to Pennsylvania are remote or hybrid as of November 2026, reflecting how well the core responsibilities of system design, code review, and architecture work translate to distributed teams. Backend, platform, and cloud infrastructure roles tend to see the highest remote availability, while roles tied to on-site hardware, classified defense programs, or regulated healthcare data systems are more likely to require a physical presence.
How can I get hired as a staff software developer in Pennsylvania with little or no experience?
The most realistic entry path is a new-graduate software engineering role at a large Pennsylvania employer followed by deliberate progression toward staff-level scope. UPMC, Comcast, and Lockheed Martin all run structured new-grad and rotational engineering programs in Pennsylvania that place people without prior industry experience. Moving into a staff role from a senior software engineer or technical lead position at a mid-size Pennsylvania company is the most common internal path. A strong public GitHub portfolio and a cloud certification recognized by major Pennsylvania employers can accelerate that progression.
Where can I find and apply to staff software developer jobs in Pennsylvania?
You can find and apply to staff software developer jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings updated regularly. Find the roles that match your experience and specialization and apply directly to each one.
See All 20 Staff Software Developer Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Staff Software Developer Jobs