Senior AI Software Engineer Jobs in Massachusetts

Senior AI Software Engineer jobs in Massachusetts are among the most active in the country, concentrated in biotech, robotics, defense technology, and enterprise software across a market that ranges from mid-level practitioners to principal engineers leading research teams. Boston, Cambridge, and the Route 128 corridor are the primary hiring hubs, with established employers like Raytheon Technologies, MathWorks, and Mass General Brigham consistently building out AI and machine learning capabilities. The most in-demand specialties include large language model development, computer vision, and MLOps infrastructure. Find a role that fits below and apply directly.

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Overview

Open roles36
Top employerWhoop
Top cityBoston, MA
Cities hiring9
Work type47% On-site
Top industryTechnology

Showing 5 of 36+ Senior AI Software Engineer jobs

Brandeis University
Lecturer in Artificial Intelligence (AI) & Management
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Brandeis University
Added 3d ago
Lecturer in Artificial Intelligence (AI) & Management
Brandeis University
Waltham, Massachusetts
Higher Education
K-12 Teaching
Teaching & Instruction
1,001-5,000

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Client Resources, Inc.
AI SR Software Engineer
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Client Resources, Inc.
Added 4d ago
AI SR Software Engineer
Client Resources, Inc.
Boston, Massachusetts
Backend Engineering
Full-stack Engineering
Software Engineering
Remote (US)
51-200

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KAYAK
Senior Software Engineer, Meta AI
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KAYAK
Added 5d ago
Senior Software Engineer, Meta AI
KAYAK
Concord, Massachusetts
Business Development
Customer Success
Program Management
Project Management
$125k - $140k/yr
Hybrid
1,001-5,000

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Wayfair
Software Engineer III - Visual AI Technology
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Wayfair
Added 5d ago
Software Engineer III - Visual AI Technology
Wayfair
Boston, Massachusetts
Customer Service
Customer Support
Hospitality & Guest Services
$160k - $176k/yr
Hybrid
10,000+

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CohnReznick
Director/Managing Director, AI Software Development
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CohnReznick
Added 1w ago
Director/Managing Director, AI Software Development
CohnReznick
Boston, Massachusetts
Cloud & DevOps
Cloud Engineering
Solutions Architecture
Technical Product & Program Management
$211k - $290k/yr
Bachelor's degree in engineering
1,001-5,000

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See All 36 Senior AI Software Engineer Jobs in Massachusetts

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Senior AI Software Engineer Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Cambridge
7 jobs
Waltham
2 jobs
Lowell
1 job
Bedford
1 job
Concord
1 job
Reading
1 job
Watertown
1 job
Charlestown
1 job

Senior AI Software Engineer Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Whoop
Whoop3 open roles
Amazon
Amazon3 open roles
Klaviyo
Klaviyo2 open roles

Top Industries Hiring

  • Technology & Software
  • Healthcare & Medical Services
  • Insurance
  • Law & Legal Services
  • Biotechnology & Pharmaceuticals

What Massachusetts Employers Look For

The qualifications that appear most often in senior AI software engineer jobs across Massachusetts.

  • Bachelor's or master's degree in computer science, machine learning, or a closely related field
  • Five or more years of hands-on experience building and deploying production AI or ML systems
  • Deep proficiency in Python and frameworks such as PyTorch, TensorFlow, or JAX
  • Experience designing MLOps pipelines, model monitoring, and scalable inference infrastructure
  • Demonstrated ability to lead technical projects and mentor junior engineers on AI teams
  • Familiarity with cloud platforms including AWS, Azure, or Google Cloud for AI workload deployment

Senior AI Software Engineer Jobs in Massachusetts: Frequently Asked Questions

How do you become a senior ai software engineer in Massachusetts?

There is no state-issued license required to work as a senior ai software engineer in Massachusetts. The typical path starts with a bachelor's degree in computer science, mathematics, or a related field, though many employers in Boston and Cambridge prioritize demonstrated ML experience and a strong project portfolio over credentials alone. Progressing to a senior role generally requires several years building production AI systems, contributing to open-source projects or research, and ideally completing graduate coursework or a master's degree to compete for positions at research-intensive employers.

How much do senior AI software engineers make in Massachusetts?

Senior AI software engineers in Massachusetts earn a median of about $165,210 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $102,810 for the lowest 10% to over $213,970 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior ai software engineers in Massachusetts?

Employers hiring senior ai software engineers in Massachusetts right now include Whoop, Amazon, and Klaviyo, based on current listings on Migrate Mate as of September 2026. Massachusetts's concentration of biotech firms, defense contractors, and university-affiliated research institutions makes it one of the more varied hiring environments for AI engineers in the country.

Which Massachusetts cities have the most senior ai software engineer jobs?

Boston, Cambridge, and Waltham have the most senior ai software engineer openings in Massachusetts. Boston and Cambridge dominate because of the density of research hospitals, biotech companies, and technology firms anchored near MIT and Harvard, while suburban Route 128 corridor cities like Waltham and Burlington host major defense and enterprise software employers that maintain large engineering headcounts.

Are there remote senior ai software engineer jobs in Massachusetts?

Yes, and more than most fields. About 53% of senior ai software engineer openings tied to Massachusetts are remote or hybrid as of September 2026, reflecting how effectively AI engineering work translates to distributed teams. Model development, research, and data pipeline work are the most commonly offered remote functions, while roles requiring close collaboration with hardware or embedded systems teams tend to require on-site presence.

How can I get hired as a senior ai software engineer in Massachusetts with little or no experience?

The most realistic entry path is a junior or associate machine learning engineer role, which large Massachusetts employers like Raytheon Technologies, MathWorks, and Boston-area biotech firms post regularly for candidates with strong academic projects or internship experience. Building a public GitHub portfolio of end-to-end ML projects is the single most effective credential substitute. Adjacent roles in data engineering, software engineering, or research assistance at university labs affiliated with MIT, Harvard, or Northeastern frequently serve as the on-ramp into applied AI positions at the same organizations.

Where can I find and apply to senior ai software engineer jobs in Massachusetts?

You can find and apply to senior ai software engineer jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings updated regularly. Find the roles that fit your experience and apply directly to the employers posting them.

See All 36 Senior AI Software Engineer Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

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