Senior AI Software Engineer Jobs in Massachusetts
Senior AI Software Engineer jobs in Massachusetts are among the most active in the country, concentrated in biotech, robotics, defense technology, and enterprise software across a market that ranges from mid-level practitioners to principal engineers leading research teams. Boston, Cambridge, and the Route 128 corridor are the primary hiring hubs, with established employers like Raytheon Technologies, MathWorks, and Mass General Brigham consistently building out AI and machine learning capabilities. The most in-demand specialties include large language model development, computer vision, and MLOps infrastructure. Find a role that fits below and apply directly.
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The School of Business and Economics (SBE) at Brandeis University seeks an instructor for the AI for Management, a 4-credit course in Spring 2027 semester.
This required MBA course prepares students first to lead the responsible adoption of AI, second to use AI effectively in their own work, and third to participate intelligently in the design of AI-enabled products and processes. The course provides a durable managerial foundation in how contemporary AI systems are trained and used, why they can produce fluent but wrong or unsafe results, and how evaluation and process controls reduce those risks. Students then apply that foundation to source-grounded research, data analysis, multimodal communication, specification-driven application building, workflow redesign, and enterprise implementation. Agentic AI is introduced early and examined in depth at a managerial level so that students can distinguish agents from fixed workflows and understand interactive, event-triggered, scheduled, proactive, tool-using, computer-using, transactional, single-agent, and multi-agent systems. The class meets for 1.5-hours, twice a week.
Candidates with minimum qualification of doctoral (Ph.D.) degree along with relevant professional qualifications and experience with Agentic AI and no-code AI, machine learning and data science will be given preference. Interested individuals should submit a short cover letter, CV and names and contact information for two references. The deadline for first consideration is September 25, 2026.
Compensation for this position between $10,00 to $12,000 depending on qualifications.
This appointment is to a position that is in a collective bargaining unit represented by SEIU Local 509.
Pay Range Disclosure
The University's pay ranges represent a good faith estimate of what Brandeis reasonably expects to pay for a position at the time of posting. The pay offered to a selected candidate during hiring will be based on factors such as (but not limited to) the scope and responsibilities of the position, the candidate's work experience and education/training, internal peer equity, and applicable legal requirements.
Equal Opportunity Statement
Brandeis University is an equal opportunity employer which does not discriminate against any applicant or employee on the basis of race, color, ancestry, religious creed, gender identity and expression, national or ethnic origin, sex, sexual orientation, pregnancy, age, genetic information, disability, caste, military or veteran status or any other category protected by law (also known as membership in a "protected class").
See All 36 Senior AI Software Engineer Jobs in Massachusetts
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Where Massachusetts roles are concentrated, by current openings.
Senior AI Software Engineer Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Technology & Software
- Healthcare & Medical Services
- Insurance
- Law & Legal Services
- Biotechnology & Pharmaceuticals
What Massachusetts Employers Look For
The qualifications that appear most often in senior AI software engineer jobs across Massachusetts.
- Bachelor's or master's degree in computer science, machine learning, or a closely related field
- Five or more years of hands-on experience building and deploying production AI or ML systems
- Deep proficiency in Python and frameworks such as PyTorch, TensorFlow, or JAX
- Experience designing MLOps pipelines, model monitoring, and scalable inference infrastructure
- Demonstrated ability to lead technical projects and mentor junior engineers on AI teams
- Familiarity with cloud platforms including AWS, Azure, or Google Cloud for AI workload deployment
Senior AI Software Engineer Jobs in Massachusetts: Frequently Asked Questions
How do you become a senior ai software engineer in Massachusetts?
There is no state-issued license required to work as a senior ai software engineer in Massachusetts. The typical path starts with a bachelor's degree in computer science, mathematics, or a related field, though many employers in Boston and Cambridge prioritize demonstrated ML experience and a strong project portfolio over credentials alone. Progressing to a senior role generally requires several years building production AI systems, contributing to open-source projects or research, and ideally completing graduate coursework or a master's degree to compete for positions at research-intensive employers.
How much do senior AI software engineers make in Massachusetts?
Senior AI software engineers in Massachusetts earn a median of about $165,210 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $102,810 for the lowest 10% to over $213,970 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior ai software engineers in Massachusetts?
Employers hiring senior ai software engineers in Massachusetts right now include Whoop, Amazon, and Klaviyo, based on current listings on Migrate Mate as of September 2026. Massachusetts's concentration of biotech firms, defense contractors, and university-affiliated research institutions makes it one of the more varied hiring environments for AI engineers in the country.
Which Massachusetts cities have the most senior ai software engineer jobs?
Boston, Cambridge, and Waltham have the most senior ai software engineer openings in Massachusetts. Boston and Cambridge dominate because of the density of research hospitals, biotech companies, and technology firms anchored near MIT and Harvard, while suburban Route 128 corridor cities like Waltham and Burlington host major defense and enterprise software employers that maintain large engineering headcounts.
Are there remote senior ai software engineer jobs in Massachusetts?
Yes, and more than most fields. About 53% of senior ai software engineer openings tied to Massachusetts are remote or hybrid as of September 2026, reflecting how effectively AI engineering work translates to distributed teams. Model development, research, and data pipeline work are the most commonly offered remote functions, while roles requiring close collaboration with hardware or embedded systems teams tend to require on-site presence.
How can I get hired as a senior ai software engineer in Massachusetts with little or no experience?
The most realistic entry path is a junior or associate machine learning engineer role, which large Massachusetts employers like Raytheon Technologies, MathWorks, and Boston-area biotech firms post regularly for candidates with strong academic projects or internship experience. Building a public GitHub portfolio of end-to-end ML projects is the single most effective credential substitute. Adjacent roles in data engineering, software engineering, or research assistance at university labs affiliated with MIT, Harvard, or Northeastern frequently serve as the on-ramp into applied AI positions at the same organizations.
Where can I find and apply to senior ai software engineer jobs in Massachusetts?
You can find and apply to senior ai software engineer jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings updated regularly. Find the roles that fit your experience and apply directly to the employers posting them.
See All 36 Senior AI Software Engineer Jobs in Massachusetts
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