AI Software Developer Jobs in Massachusetts
AI Software Developer jobs in Massachusetts are among the most actively sought roles in the country, concentrated in biotech and life sciences, financial technology, defense and aerospace, and enterprise software, with openings at every level from entry-level engineer through principal and staff AI roles. Boston, Cambridge, and the Route 128 corridor account for the majority of hiring, anchored by employers like MathWorks, HubSpot, and Raytheon Technologies, which maintain large and lasting engineering footprints in the state. The most in-demand specialties include large language model integration, machine learning operations, and applied AI for drug discovery and clinical research. Find a role that fits below and apply directly.
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Work Your Magic with us! Start your next chapter and join MilliporeSigma.
Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.
The preferred location for this role is Burlington, MA or St. Louis, MO. Other locations in the US, including remote, may also be considered.
Your Role
As the Product Specialist for Software & AI, you will drive pioneering innovation in the strategy, development, and commercialization of cutting-edge software and AI-enabled solutions that revolutionize protein science workflows. Functioning as a technical product owner, this role requires deep expertise in scientific software and digital technologies, with a strong emphasis on transforming assay knowledge, customer insights, and automation data into smart, forward-thinking, and intuitive product innovations that accelerate time-to-market.
You will collaborate closely with automation, R&D, software engineering, and data science teams to co-create advanced digital capabilities — owning the product vision and roadmap delivery — that set new standards for ease of use, reproducibility, and workflow efficiency across our Protein Sciences portfolio.
Key Responsibilities
Define and drive the technical roadmap for scientific software, data infrastructure, and AI/ML capabilities across the Protein Sciences portfolio, delivering differentiated data-driven and algorithm-enabled solutions.
Serve as the technical and innovation lead for scientific software and AI, bridging assay workflows, data models, and advanced analytics to enable next-generation protein analysis.
Identify and drive opportunities where AI and modern data methods unlock new capabilities, advancing assay development, signal processing, data harmonization, and performance monitoring beyond traditional approaches.
Translate customer, market, and workflow needs into software and AI product requirements, including data models, feature definitions, and user experiences aligned to real-world scientific applications.
Lead the integration of software, data, and automation systems, defining data capture, metadata standards, control interfaces, and interoperability across instruments and digital platforms.
Drive cross-functional product development and innovation, partnering with Software Engineering, UX, R&D, Automation, and PM Operations — managing the full product development lifecycle from concept through launch to ensure on-time, on-strategy delivery.
Evaluate and develop strategic partnerships with external software, data, and AI providers to accelerate platform capabilities and innovation.
Support go-to-market strategy and commercial enablement, applying core product management principles including product positioning, voice-of-customer synthesis, messaging, and launch execution for software and AI solutions.
Minimum Qualifications
- Bachelor’s degree in biology, bioengineering, computer science, data science, or related field.
- 5+ years of experience with scientific software, digital platforms, or data/analytics solutions in life science research.
Preferred Qualifications
- M.Sc., Ph.D., or MBA.
- Experience with AI/ML applications in assay development, signal analysis, data interpretation, or workflow optimization.
- Familiarity with cloud‑based software, data pipelines, and workflow orchestration tools.
- Strong ability to translate scientific complexity into user‑friendly digital tools.
- Experience working across biology, software, engineering, and commercial teams; familiarity with agile product management methodologies and cross-functional roadmap execution is a plus.
US Pay Range for this position: $116,600-$175,000
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!
Work Your Magic with us! Start your next chapter and join MilliporeSigma.
Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.
The preferred location for this role is Burlington, MA or St. Louis, MO. Other locations in the US, including remote, may also be considered.
Your Role
As the Product Specialist for Software & AI, you will drive pioneering innovation in the strategy, development, and commercialization of cutting-edge software and AI-enabled solutions that revolutionize protein science workflows. Functioning as a technical product owner, this role requires deep expertise in scientific software and digital technologies, with a strong emphasis on transforming assay knowledge, customer insights, and automation data into smart, forward-thinking, and intuitive product innovations that accelerate time-to-market.
You will collaborate closely with automation, R&D, software engineering, and data science teams to co-create advanced digital capabilities — owning the product vision and roadmap delivery — that set new standards for ease of use, reproducibility, and workflow efficiency across our Protein Sciences portfolio.
Key Responsibilities
Define and drive the technical roadmap for scientific software, data infrastructure, and AI/ML capabilities across the Protein Sciences portfolio, delivering differentiated data-driven and algorithm-enabled solutions.
Serve as the technical and innovation lead for scientific software and AI, bridging assay workflows, data models, and advanced analytics to enable next-generation protein analysis.
Identify and drive opportunities where AI and modern data methods unlock new capabilities, advancing assay development, signal processing, data harmonization, and performance monitoring beyond traditional approaches.
Translate customer, market, and workflow needs into software and AI product requirements, including data models, feature definitions, and user experiences aligned to real-world scientific applications.
Lead the integration of software, data, and automation systems, defining data capture, metadata standards, control interfaces, and interoperability across instruments and digital platforms.
Drive cross-functional product development and innovation, partnering with Software Engineering, UX, R&D, Automation, and PM Operations — managing the full product development lifecycle from concept through launch to ensure on-time, on-strategy delivery.
Evaluate and develop strategic partnerships with external software, data, and AI providers to accelerate platform capabilities and innovation.
Support go-to-market strategy and commercial enablement, applying core product management principles including product positioning, voice-of-customer synthesis, messaging, and launch execution for software and AI solutions.
Minimum Qualifications
- Bachelor’s degree in biology, bioengineering, computer science, data science, or related field.
- 5+ years of experience with scientific software, digital platforms, or data/analytics solutions in life science research.
Preferred Qualifications
- M.Sc., Ph.D., or MBA.
- Experience with AI/ML applications in assay development, signal analysis, data interpretation, or workflow optimization.
- Familiarity with cloud‑based software, data pipelines, and workflow orchestration tools.
- Strong ability to translate scientific complexity into user‑friendly digital tools.
- Experience working across biology, software, engineering, and commercial teams; familiarity with agile product management methodologies and cross-functional roadmap execution is a plus.
US Pay Range for this position: $116,600-$175,000
The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!
Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!
See All 38 AI Software Developer Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find AI Software Developer JobsAI Software Developer Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
AI Software Developer Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Technology & Software
- Healthcare & Medical Services
- Insurance
- Law & Legal Services
- Biotechnology & Pharmaceuticals
What Massachusetts Employers Look For
The qualifications that appear most often in AI software developer jobs across Massachusetts.
- Bachelor's or master's degree in computer science, artificial intelligence, or a related field
- Proficiency in Python and at least one ML framework such as PyTorch or TensorFlow
- Experience designing, training, and deploying machine learning or deep learning models
- Familiarity with cloud platforms including AWS, Azure, or Google Cloud for model deployment
- Strong background in data preprocessing, feature engineering, and model evaluation techniques
- Experience collaborating with cross-functional teams on production AI systems or research prototypes
AI Software Developer Jobs in Massachusetts: Frequently Asked Questions
How do you become a ai software developer in Massachusetts?
Most ai software developer roles in Massachusetts require at least a bachelor's degree in computer science, data science, or a closely related engineering discipline, though many employers in the Boston and Cambridge research corridor prefer a master's or doctoral degree for applied AI work. There is no state-issued license for this role, but candidates who complete graduate AI programs at Massachusetts institutions like MIT, Northeastern, or UMass Amherst and build a concrete project portfolio move through hiring pipelines fastest.
How much do AI software developers make in Massachusetts?
AI software developers in Massachusetts earn a median of about $165,210 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $102,810 for the lowest 10% to over $213,970 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire ai software developers in Massachusetts?
Employers hiring ai software developers in Massachusetts right now include Klaviyo, Amazon, and Revvity, based on current listings on Migrate Mate as of August 2026. Massachusetts's concentration of biotech firms, defense contractors, and enterprise software companies means AI roles here frequently sit at the intersection of scientific research and production engineering, making the employer mix more varied than in most other states.
Which Massachusetts cities have the most ai software developer jobs?
Boston, Cambridge, and Waltham have the most ai software developer openings in Massachusetts. Boston and Cambridge dominate because of the dense cluster of research universities, venture-backed AI startups, and life sciences companies in Kendall Square and the Seaport, while the Route 128 corridor cities like Waltham and Burlington draw demand from established defense and enterprise software employers that have operated in those suburbs for decades.
Are there remote ai software developer jobs in Massachusetts?
Yes, and more than most fields. About 63% of ai software developer openings tied to Massachusetts are remote or hybrid as of August 2026, reflecting how much of the work involves writing code, running experiments, and reviewing model outputs rather than on-site equipment. Research and MLOps roles tend to be the most remote-friendly, while positions that require access to proprietary on-premises computing infrastructure or regulated biomedical data often require regular in-office presence.
How can I get hired as a ai software developer in Massachusetts with little or no experience?
The most realistic entry path is applying to AI or machine learning associate engineer roles at large Massachusetts technology employers that run structured new-graduate programs, including MathWorks, which hires entry-level engineers directly from Massachusetts universities each year. Lateral moves from data analyst, software QA engineer, or research assistant positions are common, and candidates who complete a graduate AI certificate through Northeastern's Align program or demonstrate applied work on a public GitHub portfolio consistently receive more interview callbacks from Massachusetts hiring managers than those with coursework alone.
Where can I find and apply to ai software developer jobs in Massachusetts?
You can find and apply to ai software developer jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across industries and experience levels. Find the roles that fit your background and apply directly from the listing.
See All 38 AI Software Developer Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find AI Software Developer Jobs