Senior Clinical Data Manager Jobs
Senior Clinical Data Manager jobs are open across pharmaceutical, biotechnology, contract research organization, and medical device industries, from mid-level to principal and director, with specializations in clinical trial management, data integrity, and regulatory submissions. Find a role that fits from the openings below and apply directly.
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About this Role:
CBRE is the global leader in commercial real estate and the Data Center Solutions Platform specializes in data center management. Our teams keep the digital economy running around the clock without interruption.
We are seeking a Data Center Site Manager to lead our specialized technical operations. This critical role requires a professional with deep, hands-on data center experience. You must understand complex infrastructure like cooling systems, redundant power supplies, and strict uptime requirements.
In this role, your technical expertise will directly protect our clients' most valuable digital assets. You will lead skilled engineering teams and manage complex vendor networks. Your background in critical environments will ensure we maintain our industry-leading operational standards.
What You’ll Do:
- Provide formal supervision to employees. Monitor the training and development of staff. Conduct performance evaluations and coaching. Oversee the recruiting and hiring of new employees.
- Schedule and manage the team's daily activities. Establish work schedules, assign tasks, and cross-train staff. Set and track staff and department deadlines. Mentor and coach as needed.
- Coordinate and manage facility repairs and maintenance by working with technicians, vendors, and contractors.
- Maintain positive client relationships and conduct meetings on unresolved facility issues.
- Prepare and manage capital projects, operating budgets, and variance reports.
- Perform facility inspections quality assurance following local, state, and federal regulations. Suggest operational efficiencies, repairs, and upgrade opportunities.
- Manage environmental health and safety procedures for facilities.
- Oversee vendor relationships and invoicing procedures. Review price quotes for the procurement of parts, services, and labor for projects.
- Conduct process and procedure training on maintenance, repairs, and safety best practices.
- Lead by example and model behaviors that are consistent with CBRE RISE values. Influence parties of shared interests to reach an agreement.
- Apply knowledge of own discipline and how own discipline integrates with others to achieve team and departmental objectives.
- Identify, troubleshoot, and resolve day-to-day and moderately complex issues which may or may not be evident in existing systems and processes.
What You’ll Need:
- Bachelor's Degree preferred with 3-5 years of relevant experience. In lieu of a degree, a combination of experience and education will be considered. Valid driver's license required. Facility Management certification preferred.
- Experience in the areas of staffing, selection, training, development, coaching, mentoring, measuring, appraising, and rewarding performance and retention preferred.
- Ability to guide the exchange of sensitive, complicated, and difficult information, convey performance expectations and handle problems.
- Leadership skills to motivate team impact on quality, efficiency, and effectiveness of the job discipline and department.
- Extensive organizational skills with a strong inquisitive mindset.
- Advanced math skills. Ability to calculate difficult figures such as percentages, fractions, and other financial-related calculations.
Disclaimers:
Applicants must be currently authorized to work in the United States without the need for visa sponsorship now or in the future.
Equal Employment Opportunity: CBRE has a long-standing commitment to providing equal employment opportunity to all qualified applicants regardless of race, color, religion, national origin, sex, sexual orientation, gender identity, pregnancy, age, citizenship, marital status, disability, veteran status, political belief, or any other basis protected by applicable law.
Candidate Accommodations: CBRE values the differences of all current and prospective employees and recognizes how every employee contributes to our company’s success. CBRE provides reasonable accommodations in job application procedures for individuals with disabilities. If you require assistance due to a disability in the application or recruitment process, please submit a request via email at recruitingaccommodations@cbre.com or via telephone at +1 866 225 3099 (U.S.) and +1 866 388 4346 (Canada).
About this Role:
CBRE is the global leader in commercial real estate and the Data Center Solutions Platform specializes in data center management. Our teams keep the digital economy running around the clock without interruption.
We are seeking a Data Center Site Manager to lead our specialized technical operations. This critical role requires a professional with deep, hands-on data center experience. You must understand complex infrastructure like cooling systems, redundant power supplies, and strict uptime requirements.
In this role, your technical expertise will directly protect our clients' most valuable digital assets. You will lead skilled engineering teams and manage complex vendor networks. Your background in critical environments will ensure we maintain our industry-leading operational standards.
What You’ll Do:
- Provide formal supervision to employees. Monitor the training and development of staff. Conduct performance evaluations and coaching. Oversee the recruiting and hiring of new employees.
- Schedule and manage the team's daily activities. Establish work schedules, assign tasks, and cross-train staff. Set and track staff and department deadlines. Mentor and coach as needed.
- Coordinate and manage facility repairs and maintenance by working with technicians, vendors, and contractors.
- Maintain positive client relationships and conduct meetings on unresolved facility issues.
- Prepare and manage capital projects, operating budgets, and variance reports.
- Perform facility inspections quality assurance following local, state, and federal regulations. Suggest operational efficiencies, repairs, and upgrade opportunities.
- Manage environmental health and safety procedures for facilities.
- Oversee vendor relationships and invoicing procedures. Review price quotes for the procurement of parts, services, and labor for projects.
- Conduct process and procedure training on maintenance, repairs, and safety best practices.
- Lead by example and model behaviors that are consistent with CBRE RISE values. Influence parties of shared interests to reach an agreement.
- Apply knowledge of own discipline and how own discipline integrates with others to achieve team and departmental objectives.
- Identify, troubleshoot, and resolve day-to-day and moderately complex issues which may or may not be evident in existing systems and processes.
What You’ll Need:
- Bachelor's Degree preferred with 3-5 years of relevant experience. In lieu of a degree, a combination of experience and education will be considered. Valid driver's license required. Facility Management certification preferred.
- Experience in the areas of staffing, selection, training, development, coaching, mentoring, measuring, appraising, and rewarding performance and retention preferred.
- Ability to guide the exchange of sensitive, complicated, and difficult information, convey performance expectations and handle problems.
- Leadership skills to motivate team impact on quality, efficiency, and effectiveness of the job discipline and department.
- Extensive organizational skills with a strong inquisitive mindset.
- Advanced math skills. Ability to calculate difficult figures such as percentages, fractions, and other financial-related calculations.
Disclaimers:
Applicants must be currently authorized to work in the United States without the need for visa sponsorship now or in the future.
Equal Employment Opportunity: CBRE has a long-standing commitment to providing equal employment opportunity to all qualified applicants regardless of race, color, religion, national origin, sex, sexual orientation, gender identity, pregnancy, age, citizenship, marital status, disability, veteran status, political belief, or any other basis protected by applicable law.
Candidate Accommodations: CBRE values the differences of all current and prospective employees and recognizes how every employee contributes to our company’s success. CBRE provides reasonable accommodations in job application procedures for individuals with disabilities. If you require assistance due to a disability in the application or recruitment process, please submit a request via email at recruitingaccommodations@cbre.com or via telephone at +1 866 225 3099 (U.S.) and +1 866 388 4346 (Canada).
Senior Clinical Data Manager Jobs by Experience Level
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Find JobsSenior Clinical Data Manager Job Market
Who's Hiring
- Katalyst Healthcares & Life Sciences10
- Amazon5
- AbbVie3
- CBRE2
- Moody's2
Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Education
- Technology & Software
- Healthcare & Medical Services
- Retail
What Employers Look For
The qualifications that appear most often in senior clinical data manager jobs.
- Bachelor's degree in life sciences, statistics, or a related field
- Five or more years of clinical data management experience across multiple trial phases
- Proficiency with EDC systems such as Medidata Rave, Oracle Clinical, or Veeva Vault
- Hands-on experience authoring and executing Data Management Plans
- Working knowledge of CDISC standards including CDASH, SDTM, and ADaM
- Experience with regulatory submissions and FDA or EMA data compliance requirements
Tips for Your Senior Clinical Data Manager Job Search
Tailor your resume to CDISC standards
Hiring managers scan for CDISC compliance experience before anything else. List specific CDASH, SDTM, and ADaM implementation work by study type and phase, not just familiarity. Generic 'data management experience' gets filtered out at the resume screen.
Highlight your DMP ownership experience
Senior roles almost always require you to author or own the Data Management Plan. If you've led DMP development from protocol review through database lock, call that out explicitly on your resume with the therapeutic area and phase of the trial.
Apply early to roles that fit
Migrate Mate lists senior clinical data manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Filter openings by therapeutic area depth
Oncology, rare disease, and CNS sponsors often require therapeutic-area-specific data management experience. Target openings where your trial history aligns closely with the sponsor's pipeline, since interviewers will probe protocol-level familiarity in technical screens.
Prepare to walk through a discrepancy resolution
Technical interviews for senior clinical data manager roles routinely include a scenario where you're shown a data listing with inconsistencies and asked to work through your resolution process. Practice narrating your query management and edit check logic out loud before your interview.
Negotiate scope, not just compensation
At the senior level, the number of concurrent studies, vendor oversight responsibility, and whether you're managing junior CDMs significantly affects workload. Clarify these boundaries before accepting an offer, as they directly shape your day-to-day role.
Senior Clinical Data Manager Jobs: Frequently Asked Questions
Which companies are hiring the most senior clinical data managers?
The companies hiring the most senior clinical data managers right now include Katalyst Healthcares & Life Sciences, Amazon, and AbbVie, with the largest share of openings in California, New Jersey, and Massachusetts, based on current listings on Migrate Mate as of November 2026. CROs and mid-size biotech sponsors tend to post the highest volume of senior-level openings relative to their overall headcount.
How many senior clinical data manager jobs are remote?
About 73% of senior clinical data manager openings are fully remote or hybrid as of November 2026, making it one of the more location-flexible roles in clinical operations. Data review, query management, and vendor oversight work tends to be the most remote-compatible, while roles tied to site-level data collection or hands-on EDC build work are more likely to require periodic on-site presence.
How do you become a senior clinical data manager?
Start with a degree in a life science, health informatics, or statistics field, then build your foundation in a clinical data coordinator or CDM role at a CRO or sponsor. Gain hands-on EDC system experience, work across multiple trial phases, earn CDISC certification, and take on DMP ownership and cross-functional lead responsibilities before moving into a senior title.
Can you get hired as a senior clinical data manager without direct senior-level experience?
Yes, if you've functioned in a lead capacity without the formal title. Employers weight demonstrated DMP authorship, independent query resolution, and vendor or CRO oversight over the specific title you held. Candidates who've led database lock activities or mentored junior staff on a trial often successfully transition into senior roles even without a senior CDM title on their resume.
What does the senior clinical data manager interview process look like?
Most processes run three to four rounds. A recruiter screen is typically followed by a hiring manager conversation focused on trial experience and EDC system depth. A technical interview then covers data review scenarios, edit check logic, or discrepancy resolution. Final rounds often include a cross-functional panel with clinical operations, biostatistics, or regulatory affairs stakeholders who assess your collaboration and communication style.
Where can I find and apply to senior clinical data manager jobs?
You can find and apply to senior clinical data manager jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your experience in trial phase, therapeutic area, and EDC platform, then apply directly to each one that fits.
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