Senior Clinical Data Manager Jobs in Greenville, SC
Senior Clinical Data Manager jobs in Greenville, South Carolina are in active demand, concentrated in the Verdae corridor, downtown medical district, and the Eastside near Prisma Health and research-affiliated campuses, across clinical research organizations, pharmaceutical services, and health systems. Employers hiring right now include Fluor, Jacobs, and Purpose Financial. Scan the live roles below and apply to whichever ones fit.
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Hands & Eyes Services
" Installation and Removal of IT equipment
" Basic troubleshooting and repair of IT equipment failures
" Basic device configuration and OS Loads
Inventory Management Services
" Inventory Management Tracking
" Shipping/Receiving and Loading Dock
" Equipment Destruction
Media Administration Services
" Physical Media Activities
" Media Library Services
" Physical Media Audits
Cabling
" Cable Installation and Planning
" Cable Disconnect and removal
" Cable troubleshooting and repair
General Services
" Escorting of vendors and customers
" Internal & External Audit Support
" Documentation and Reporting
Basic data center planning
Pay: $25.97 - $30.00 per hour
Benefits:
- Dental insurance
- Health insurance
- Vision insurance
Experience:
- Data center: 2 years (Preferred)
- Cabling: 2 years (Preferred)
- Cat5: 2 years (Preferred)
- Cat6: 2 years (Preferred)
Work Location: In person
See All 31 Senior Clinical Data Manager Jobs in Greenville
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Find JobsSenior Clinical Data Manager Job Market in Greenville
Who's Hiring
- Fluor9

- Jacobs7

- Purpose Financial5

- Prisma Health2

- Integrated Power Services2

Top Industries Hiring
- Construction & Real Estate2
- Healthcare & Medical Services2
- Education1
- Manufacturing1
- Consulting & Professional Services1
Senior Clinical Data Manager Jobs in Greenville: Frequently Asked Questions
How do I get a senior clinical data manager job in Greenville?
Focus on Greenville's concentration of clinical research organizations, health systems like Prisma Health, and life sciences contractors operating near the I-385 corridor and Verdae area. Candidates with hands-on experience in EDC platforms such as Medidata Rave or Oracle Clinical, along with demonstrated study close-out or audit-readiness work, stand out locally. Familiarity with oncology or cardiovascular trials is a consistent edge in this market.
Which companies hire senior clinical data managers in Greenville?
Companies currently hiring senior clinical data managers in Greenville include Fluor, Jacobs, and Purpose Financial, per current listings on Migrate Mate as of July 2026. The local employer mix leans toward health systems with embedded research divisions and contract research organizations serving pharmaceutical sponsors from offices in and around Greenville.
Are there remote senior clinical data manager jobs in Greenville?
Yes, and senior clinical data manager work is well suited to remote arrangements given its desk-based, data-intensive nature. About 73% of senior clinical data manager openings tied to Greenville are remote or hybrid as of July 2026, reflecting broader industry flexibility for this role. Database design, data review, and vendor oversight tasks are the functions most commonly performed remotely by Greenville-based professionals.
How can I get a senior clinical data manager job in Greenville with little or no experience?
The most realistic entry path in Greenville is moving up from a clinical data coordinator or data analyst role at a local CRO or within Prisma Health's research operations. Greenville employers regularly promote coordinators who demonstrate proficiency in data validation and CDISC standards. Volunteering for study close-out activities or cross-training on CDASH mapping at your current organization builds the profile that local hiring managers look for at the senior level.
Which industries hire the most senior clinical data managers in Greenville?
Most senior clinical data manager openings in Greenville sit in Construction & Real Estate, Healthcare & Medical Services, and Education, per current listings on Migrate Mate as of July 2026. Greenville's growth as a regional healthcare hub anchored by Prisma Health and its affiliated research programs, combined with an expanding life sciences services sector in the Upstate corridor, drives consistent demand for experienced data management professionals.
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