Senior Clinical Data Manager Jobs in Greenville, SC

Senior Clinical Data Manager jobs in Greenville, South Carolina are in active demand, concentrated in the Verdae corridor, downtown medical district, and the Eastside near Prisma Health and research-affiliated campuses, across clinical research organizations, pharmaceutical services, and health systems. Employers hiring right now include Fluor, Jacobs, and Purpose Financial. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles31
Top employerFluor
Work type53% Hybrid
Top credentialBachelor's degree
Companies hiring11

Showing 5 of 31+ Senior Clinical Data Manager jobs

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Data Center Technician
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New 1m ago
Data Center Technician
Pyramid
Greenville, South Carolina
IT Support
Project Management
Technical Program Management
On-Site

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Jacobs
Construction Project Engineer II (Data Centers)
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Jacobs
New 1m ago
Construction Project Engineer II (Data Centers)
Jacobs
Greenville, South Carolina
Business Operations
Project Management
Hybrid
Bachelor's degree in construction management
10,000+

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Jacobs
Construction Project Engineer III (Data Centers)
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Jacobs
New 1m ago
Construction Project Engineer III (Data Centers)
Jacobs
Greenville, South Carolina
Business Operations
Project Management
Hybrid
Bachelor's degree in construction management
10,000+

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Jacobs
Senior Civil Engineer SME - AI Data Centers
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Jacobs
New 1m ago
Senior Civil Engineer SME - AI Data Centers
Jacobs
Greenville, South Carolina
Engineering (Non-Software)
Project Management
Technical Program Management
Hybrid
Bachelor's degree
10,000+

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Prisma Health
Mgr-Physician Practice I F/T Day
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Prisma Health
New 1m ago
Mgr-Physician Practice I F/T Day
Prisma Health
Greenville, South Carolina
Business Operations
Human Resources
Project Management
Bachelor's degree in business administration
10,000+

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See All 31 Senior Clinical Data Manager Jobs in Greenville

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Senior Clinical Data Manager Job Market in Greenville

Who's Hiring

  • Fluor
    Fluor9
  • Jacobs
    Jacobs7
  • Purpose Financial
    Purpose Financial5
  • Prisma Health
    Prisma Health2
  • Integrated Power Services
    Integrated Power Services2

Top Industries Hiring

  • Construction & Real Estate2
  • Healthcare & Medical Services2
  • Education1
  • Manufacturing1
  • Consulting & Professional Services1

Senior Clinical Data Manager Jobs in Greenville: Frequently Asked Questions

How do I get a senior clinical data manager job in Greenville?

Focus on Greenville's concentration of clinical research organizations, health systems like Prisma Health, and life sciences contractors operating near the I-385 corridor and Verdae area. Candidates with hands-on experience in EDC platforms such as Medidata Rave or Oracle Clinical, along with demonstrated study close-out or audit-readiness work, stand out locally. Familiarity with oncology or cardiovascular trials is a consistent edge in this market.

Which companies hire senior clinical data managers in Greenville?

Companies currently hiring senior clinical data managers in Greenville include Fluor, Jacobs, and Purpose Financial, per current listings on Migrate Mate as of July 2026. The local employer mix leans toward health systems with embedded research divisions and contract research organizations serving pharmaceutical sponsors from offices in and around Greenville.

Are there remote senior clinical data manager jobs in Greenville?

Yes, and senior clinical data manager work is well suited to remote arrangements given its desk-based, data-intensive nature. About 73% of senior clinical data manager openings tied to Greenville are remote or hybrid as of July 2026, reflecting broader industry flexibility for this role. Database design, data review, and vendor oversight tasks are the functions most commonly performed remotely by Greenville-based professionals.

How can I get a senior clinical data manager job in Greenville with little or no experience?

The most realistic entry path in Greenville is moving up from a clinical data coordinator or data analyst role at a local CRO or within Prisma Health's research operations. Greenville employers regularly promote coordinators who demonstrate proficiency in data validation and CDISC standards. Volunteering for study close-out activities or cross-training on CDASH mapping at your current organization builds the profile that local hiring managers look for at the senior level.

Which industries hire the most senior clinical data managers in Greenville?

Most senior clinical data manager openings in Greenville sit in Construction & Real Estate, Healthcare & Medical Services, and Education, per current listings on Migrate Mate as of July 2026. Greenville's growth as a regional healthcare hub anchored by Prisma Health and its affiliated research programs, combined with an expanding life sciences services sector in the Upstate corridor, drives consistent demand for experienced data management professionals.

See All 31 Senior Clinical Data Manager Jobs in Greenville

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