Senior Clinical Project Manager Jobs in Greenville, SC

Senior Clinical Project Manager jobs in Greenville concentrate in the Verdae and Haywood Road corridors and around the Greenville Health System campus, across clinical research, pharmaceutical services, and contract research organizations. Employers actively hiring include Prisma Health, GE Vernova, and Bon Secours. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles120+
Top employerPrisma Health
Work type68% On-site
Top credentialBachelor's degree in mechanical engineering
Companies hiring65

Showing 5 of 120+ Senior Clinical Project Manager jobs

GE Vernova
Lead Engineer - Mechanical Components
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GE Vernova
New 1m ago
Lead Engineer - Mechanical Components
GE Vernova
Greenville, South Carolina
Software Engineering
Solutions Engineering & Architecture
Technical Program Management
Bachelor's degree in mechanical engineering
10,000+

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AT&T
Sr Specialist Sales Sys Engineer 1-Ter
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AT&T
New 1m ago
Sr Specialist Sales Sys Engineer 1-Ter
AT&T
Greenville, South Carolina
Account Management
Business Development
Sales
Bachelor of Science
10,000+

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Zachry Group
Principal Engineer Mechanical (Lead)
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Zachry Group
New 1m ago
Principal Engineer Mechanical (Lead)
Zachry Group
Greenville, South Carolina
Business Strategy
Product Management
Project Management
Bachelor's degree in mechanical engineering
10,000+

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LifeStance Health
Licensed Clinical Therapist (LPC/LISW-CP/LMFT)
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LifeStance Health
New 1m ago
Licensed Clinical Therapist (LPC/LISW-CP/LMFT)
LifeStance Health
Greenville, South Carolina
Caregiving & Elderly Support
Healthcare Administration
Nursing
Patient Services & Wellbeing
Hybrid
5,001-10,000

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LifeStance Health
Clinical Testing Psychologist (PhD/PsyD)
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LifeStance Health
New 1m ago
Clinical Testing Psychologist (PhD/PsyD)
LifeStance Health
Greenville, South Carolina
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
$133k - $160k/yr
Hybrid
Doctoral degree in clinical psychology
5,001-10,000

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See All 120+ Senior Clinical Project Manager Jobs in Greenville

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Senior Clinical Project Manager Job Market in Greenville

Who's Hiring

  • Prisma Health
    Prisma Health17
  • GE Vernova
    GE Vernova14
  • Bon Secours
    Bon Secours6
  • Lockheed Martin
    Lockheed Martin3
  • Ogletree Deakins
    Ogletree Deakins3

Top Industries Hiring

  • Healthcare & Medical Services24
  • Consulting & Professional Services13
  • Energy8
  • Construction & Real Estate6
  • Technology & Software5

Senior Clinical Project Manager Jobs in Greenville: Frequently Asked Questions

How do I get a senior clinical project manager job in Greenville?

The strongest path into Greenville's market is through its clinical research and health system infrastructure. Prisma Health and the broader Upstate medical corridor drive consistent demand, and contract research organizations operating out of the Verdae and downtown districts regularly hire experienced project managers. Candidates with oncology or device trial experience and PMP or CAPM credentials tend to stand out in local postings.

Which companies hire senior clinical project managers in Greenville?

Companies currently hiring senior clinical project managers in Greenville include Prisma Health, GE Vernova, and Bon Secours, per current listings on Migrate Mate as of July 2026. Hiring tends to cluster among health systems, regional CROs, and pharmaceutical services firms with a presence in Upstate South Carolina.

Are there remote senior clinical project manager jobs in Greenville?

Yes, though availability depends on the role: sponsor-side oversight and data management functions are often remote-eligible, while site coordination and hands-on trial management typically require on-site presence. About 32% of senior clinical project manager openings tied to Greenville are remote or hybrid as of July 2026. Protocol management and regulatory submission work represent the most remote-friendly functions in the local market.

How can I get a senior clinical project manager job in Greenville with little or no experience?

The most realistic entry path in Greenville is through a clinical coordinator or study coordinator role at Prisma Health or one of its affiliated research sites, then building toward a senior project manager title over time. Local CROs and pharmaceutical services firms in the Verdae corridor also hire project coordinators who can move into manager tracks. Demonstrating familiarity with ICH-GCP guidelines and any direct trial site experience gives candidates a clear edge with Greenville employers.

Which industries hire the most senior clinical project managers in Greenville?

Greenville senior clinical project manager roles concentrate in Healthcare & Medical Services, Consulting & Professional Services, and Energy, based on current listings on Migrate Mate as of July 2026. Greenville's position as the hub of Upstate South Carolina's medical and life sciences community, anchored by its major health system and a growing CRO presence, is what drives hiring across those sectors.

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