Senior Clinical Project Manager Jobs in Greenville, SC
Senior Clinical Project Manager jobs in Greenville concentrate in the Verdae and Haywood Road corridors and around the Greenville Health System campus, across clinical research, pharmaceutical services, and contract research organizations. Employers actively hiring include Prisma Health, GE Vernova, and Bon Secours. Scan the live roles below and apply to whichever ones fit.
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What impact you’ll make
As a member of the HA DLN2.6e Combustor Team, you will be an active contributor in delivering quality products across multiple platforms that differentiate GE Vernova from its competition. As a lead mechanical design engineer, you will be empowered to design and create solutions for the most advanced and highest performing combustion systems on the market.
Job Description
What you’ll do
- Design HA DLN2.6e combustion systems leveraging hand calculations, 3D Modeling software, Finite Element Analysis (FEA), component and rig testing to meet program requirements.
- Communicate technical risk to stakeholders
- Drive quality of our products through completion of design stack ups and robust qualifications.
- Work cross functionally across engineering and manufacturing teams to deliver high quality products to our customers, on time.
- Implements lean and continuous improvement to engineering tasks.
- Documents work clearly and effectively presents work in formal and informal reviews.
- May Lead small focused projects to support larger programs
- Act as resource for colleagues with less experience.
What you’ll bring (Basic Qualifications)
- Minimum 4 Years of relevant experience in mechanical design
- Bachelor’s degree in mechanical engineering, Aerospace Engineering or closely related engineering discipline from an accredited university or college; or relevant experience that would be equal to a bachelor’s degree.
What will make you stand out
- 2 years or more of Combustion Design Experience
- Masters Degree in Mechanical Engineering, Aerospace Engineering or closely related engineering discipline
- Experience in design for manufacturing and / or design for additive manufacturing
- Demonstrated ability to manage multiple projects across multiple competing priorities
- Demonstrated capability in collaborating with global teams
- Strong organizational and communication skills
Benefits Available to You
GE Vernova employees rise to the challenge of building a world that works. In order to meet this mission, we provide varied, competitive benefits to help support our workforce: Our Culture | GE Vernova (gecareers.com)
Our compensation & benefits are designed to reward high performers and help you manage your personal and family needs. We offer a robust benefits package depending on your employment status and your national requirements.
A healthy, balanced lifestyle can mean different things to different people. We've created programs that support the way you live and work today.
GE Vernova invests to provide opportunities to grow your career by providing a path for continued on-the-job learning and development.
GE Vernova offers a great work environment, professional development, challenging careers, and competitive compensation. GE Vernova is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, religion, national or ethnic origin, sex, sexual orientation, gender identity or expression, age, disability, protected veteran status or other characteristics protected by law.
GE Vernova will only employ those who are legally authorized to work in the United States for this opening. Any offer of employment is conditioned upon the successful completion of a drug screen (as applicable).
Relocation Assistance Provided: Yes
This posting is expected to remain open for at least seven days after it was posted on July 02, 2026.
Available benefits include medical, dental, vision, and prescription drug coverage; access to Health Coach from GE Vernova, a 24/7 nurse-based resource; and access to the Employee Assistance Program, providing 24/7 confidential assessment, counseling and referral services. Retirement benefits include the GE Vernova Retirement Savings Plan, a tax-advantaged 401(k) savings opportunity with company matching contributions and company retirement contributions, as well as access to Fidelity resources and financial planning consultants. Other benefits include tuition assistance, adoption assistance, paid parental leave, disability benefits, life insurance, 12 paid holidays, and permissive time off.
GE Vernova Inc. or its affiliates (collectively or individually, “GE Vernova”) sponsor certain employee benefit plans or programs GE Vernova reserves the right to terminate, amend, suspend, replace, or modify its benefit plans and programs at any time and for any reason, in its sole discretion. No individual has a vested right to any benefit under a GE Vernova welfare benefit plan or program. This document does not create a contract of employment with any individual.
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Find JobsSenior Clinical Project Manager Job Market in Greenville
Who's Hiring
- Prisma Health17

- GE Vernova14

- Bon Secours6

- Lockheed Martin3

- Ogletree Deakins3

Top Industries Hiring
- Healthcare & Medical Services24
- Consulting & Professional Services13
- Energy8
- Construction & Real Estate6
- Technology & Software5
Senior Clinical Project Manager Jobs in Greenville: Frequently Asked Questions
How do I get a senior clinical project manager job in Greenville?
The strongest path into Greenville's market is through its clinical research and health system infrastructure. Prisma Health and the broader Upstate medical corridor drive consistent demand, and contract research organizations operating out of the Verdae and downtown districts regularly hire experienced project managers. Candidates with oncology or device trial experience and PMP or CAPM credentials tend to stand out in local postings.
Which companies hire senior clinical project managers in Greenville?
Companies currently hiring senior clinical project managers in Greenville include Prisma Health, GE Vernova, and Bon Secours, per current listings on Migrate Mate as of July 2026. Hiring tends to cluster among health systems, regional CROs, and pharmaceutical services firms with a presence in Upstate South Carolina.
Are there remote senior clinical project manager jobs in Greenville?
Yes, though availability depends on the role: sponsor-side oversight and data management functions are often remote-eligible, while site coordination and hands-on trial management typically require on-site presence. About 32% of senior clinical project manager openings tied to Greenville are remote or hybrid as of July 2026. Protocol management and regulatory submission work represent the most remote-friendly functions in the local market.
How can I get a senior clinical project manager job in Greenville with little or no experience?
The most realistic entry path in Greenville is through a clinical coordinator or study coordinator role at Prisma Health or one of its affiliated research sites, then building toward a senior project manager title over time. Local CROs and pharmaceutical services firms in the Verdae corridor also hire project coordinators who can move into manager tracks. Demonstrating familiarity with ICH-GCP guidelines and any direct trial site experience gives candidates a clear edge with Greenville employers.
Which industries hire the most senior clinical project managers in Greenville?
Greenville senior clinical project manager roles concentrate in Healthcare & Medical Services, Consulting & Professional Services, and Energy, based on current listings on Migrate Mate as of July 2026. Greenville's position as the hub of Upstate South Carolina's medical and life sciences community, anchored by its major health system and a growing CRO presence, is what drives hiring across those sectors.
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