Senior Clinical Project Manager Jobs
Senior Clinical Project Manager jobs are open across pharmaceutical, biotechnology, medical device, and contract research organizations, from mid-level to executive, with specializations in oncology trials, regulatory affairs, and global study management. Find a role that fits from the openings below and apply directly.
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NYU Langone Hospital—Suffolk is a 306-bed medical center, providing care to residents of eastern Long Island. The hospital facility is home to the Knapp Cardiac Care Center—an advanced heart disease diagnostic and treatment facility—as well as a modern ambulatory surgical pavilion with specialized services including women's imaging, a sleep laboratory, and bariatric surgery. Our Provisional Level 2 Trauma Center delivers comprehensive and specialized care for patients with traumatic injuries. The Stroke Center at NYU Langone Hospital—Suffolk is designated by the New York State Department of Health as a Primary Stroke Center, with expert neurologists available to provide treatment 24 hours a day, 7 days a week. Additionally, NYU Langone Hospital—Suffolk has multiple outpatient sites, including an outpatient wound care center, a hemodialysis center, and various primary care and specialty offices.
For more information, go to NYU Langone Hospital—Suffolk, and interact with us on LinkedIn, Glassdoor, Indeed, Facebook, X, YouTube and Instagram.
Position Summary:
We have an exciting opportunity to join our team as a Clinical Coordinator-Clinical ALERT- Full Time- Night Shift- 7 pm - 8 am - NSG- Clinical ALERT - -.
In this role, the successful candidate Responsible for the provision of nursing care to patients with multiple and complex health care needs. Responsible for hiring, training, orientation and performance management process for designated staff. Assumes responsibility for the coordination of designated management of patient care for critical patients on assigned shift. Serves as a resource to other staff members. Acts as a consultant to colleagues and other health team members on matters concerning patient management. Serves a s a role model to other staff and advocates for patients/families/significant others. Assumes accountability for own professional practice and aspects of care delegated to others. Practices within ethical and legal parameters of nursing. This description covers the essential functions of the position. Incumbent is expected to perform similar and related duties as assigned.
Job Responsibilities:
Management of Clinical Operations:
- Assumes responsibility for shift issues in collaboration with other Clinical Coordinators, Nursing Professional Development, NAS, & Nurse Managers to provide a seamless system of support and accountability for Critical Patients for 24-hour shift operations.
- Collaborates with the development of nursing and departmental standards with practice monitoring that is in compliance with state and local regulatory agencies
- Participates in departmental initiatives that support the departmental goals and have identified measurable outcomes.
- Role models a leadership style that recognizes the values and limitations of others, but is able to maximize enhanced levels of expectation between each individual and other departments. Assists administrative staff with the development of an environment that exhibits open, honest communication.
- Designs interventions in the coordination of patient care in a safe, timely and appropriate manner. Applies, oversees and ensures the escalation process. Considers needs and behaviors of specific patient age groups and cultural groups in all patient care activities. Documents interventions per hospital standard.
- Maintains and applies current evidence-based practice principles in nursing and operations to improve clinical care through professional development initiatives.
- Manages and leads Codes & Rapid Responses and prepares the staff to respond effectively to emergency management situations.
- Demonstrates expert level of clinical practice when functioning in a nursing clinical role. Role models creative interventions to meet the age-specific and culturally sensitive nursing care needs of all patients.
- Manages direction of emergency situations and appropriately delegates staff to meet these needs.
- Serves as a staff resource for departmental standards of care policy procedures.
Management of Personnel:
- Provides leadership and coordinates activities for the daily operational requirements that support an effective environment for staff.
- Develops operational policies, procedures and problem solutions. Provides and evaluates them so that their effectiveness correlates to intent; and holds department staff members accountable for compliance.
- Fosters an environment that encourages staff participation in modifying/improving unit operations by role modeling and mentoring staff.
- Completes and approves daily staffing assignments and change requests based on acuity, volume and staff competencies. Adjusts staffing level to support and promote patient staffing needs.
- Manages patient flow through all areas of the department and hospital if necessary, which is based on acuity and
patient needs by alleviating bottlenecks and barriers. Consults Nurse Managers, NAS & DON to redirect and or prioritize activities when needed. - Serves as a liaison with other departments, to promote the patient's continuum of care. Escalates issues when necessary to the Night Administrator, Nurse Manager, NAS &/or DON.
- Implements a timely and responsive action plan for patient/family and department complaints with feedback to the Department of Quality Management and Patient Advocacy Office.
Participates in Performance Improvement Activities:
- Evaluates dimensions of clinical practice, which evaluates the process of care and identify opportunities for change if variances are trended. Such as decreasing restraints & falls, increasing Patient Satisfaction, etc..
- Builds processes and encourages staff development to promote satisfaction and service recovery that increase the qualitative and quantitative measurements of patient and staff satisfaction.
- Participates in Performance Improvement activities, DOH, IPRO & other regulatory agency reviews required.
Staff Education:
- Provide ongoing feedback and education to individuals regarding their documentation practices. Consistent variances are documented and staff held accountable for improvements.
- Participates in the development and monitoring of the department budget and financial practices.
- Identifies opportunities for cost reduction and revenue enhancement.
Collegiality/Professionalism:
- Identifies him/herself to the patient; wears hospital ID and clarifies his/her role to the patient in an understandable and respectful fashion.
- Each staff member will exhibit actions that support the comfort and safety of patients and their families.
- Professional decorum is to be manifested through all patient interactions whether they be in person; on the telephone or with non-verbal communications.
- Assumes personal responsibility for each patient/staff interaction. Acknowledges any service issues with the patient and makes every attempt to provide service recovery interventions to assist with the resolution of the problem.
Teamwork/Collaboration:
- Communicates in a fashion that respects the individuality and dignity of each person. Promotes dialogue that is honest and non-confrontational.
- When there are disagreements regarding issues he/she will make a personal attempt to resolve the problem in a collaborative manner that promotes a successful encounter.
- Demonstrates a willingness to be flexible in his/her day-to-day activities to meet the needs of individual patients or the department.
- Demonstrates through his/her actions that the patient and or departmental goals are a priority.
Minimum Qualifications:
To qualify you must have a Bachelor's Degree in Nursing required.
Current and valid NYS Registered Nurse License.
Basic Life Support (BLS) certification, active and current through the American Heart Association (AHA).
Advanced Cardiovascular Life Support (ACLS) certification, active and current through the American Heart Association (AHA).
Minimum 3-5 years of nursing experience.
Demonstrates nursing competence as an expert level practitioner.
Demonstrates ability to problem solve; serve as a mentor, respond as an active member of a multidisciplinary team.
Exhibits excellent time management and priority setting skills.
Frequently lifts/carries up to 25 lbs.
Frequently pushes/pulls more than 100 lbs.
Frequently bends, squats, kneels, climbs steps/ladders and reaches above shoulders..
Required Licenses: Registered Nurse License-NYS
Preferred Qualifications:
Previous nursing management experience is preferred.
NYU Langone Hospital—Suffolk provides its staff with far more than just a place to work. Rather, we are an institution you can be proud of, an institution where you'll feel good about devoting your time and your talents.
NYU Langone Hospital—Suffolk is an equal opportunity employer and committed to inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration. We require applications to be completed online.
View Know Your Rights: Workplace discrimination is illegal.
NYU Langone Hospital-Suffolk provides a salary range to comply with the New York state Law on Salary Transparency in Job Advertisements. The salary range for the role is $84,956.87 - $134,127.10 Annually. Actual salaries depend on a variety of factors, including experience, specialty, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.
View the Pay Transparency Notice for further details.
Senior Clinical Project Manager Jobs by Experience Level
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Who's Hiring



Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Healthcare & Medical Services
- Education
- Insurance
- Technology & Software
What Employers Look For
The qualifications that appear most often in senior clinical project manager jobs.
- Bachelor's or advanced degree in life sciences, nursing, or a related clinical field
- Minimum five to eight years of clinical trial management experience across multiple phases
- Proficiency with clinical trial management systems such as Veeva Vault or Medidata Rave
- Project Management Professional or equivalent certification preferred by most sponsors
- Deep knowledge of ICH E6 Good Clinical Practice guidelines and FDA regulatory requirements
- Experience managing CROs, budgets, and cross-functional teams on global or multi-site studies
Tips for Your Senior Clinical Project Manager Job Search
Tailor your resume to ICH E6 language
Hiring managers scan for familiarity with ICH E6 Good Clinical Practice guidelines. Use that exact phrasing when describing protocol oversight or monitoring experience, because applicant tracking systems filter for it before a human ever sees your resume.
Highlight cross-functional budget ownership
Senior roles require direct accountability for study budgets, not just cost tracking. Describe specific phases where you owned vendor contracts, managed CRO invoicing, or handled budget variance reporting to show you can lead financial decisions, not just report them.
Apply early to roles that fit
Migrate Mate lists senior clinical project manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Filter by therapeutic area before applying
Oncology, rare disease, and neuroscience trials each have distinct regulatory timelines and site management demands. Targeting openings that match your therapeutic background makes your application more credible and shortens the ramp-up conversation in interviews.
Prepare a study startup timeline case study
Interviewers at senior level routinely ask you to walk through a complex startup scenario. Have a real example ready that covers site selection, IRB submission timelines, and enrollment delays, and be specific about what you controlled versus escalated.
Negotiate scope before title when switching sponsors
Moving from a CRO to a sponsor, or vice versa, often resets perceived seniority. Before accepting an offer, clarify study portfolio size, number of direct reports, and global versus regional scope, because those determine your actual leverage in future negotiations more than the title does.
Senior Clinical Project Manager Jobs: Frequently Asked Questions
Which companies are hiring the most senior clinical project managers?
The companies hiring the most senior clinical project managers right now include Success Education Colleges, Abbott, and Immunome, with the largest share of openings in California, New York, and North Carolina, based on current listings on Migrate Mate as of September 2026. Pharmaceutical sponsors and large CROs consistently account for the highest volume of active postings.
How many senior clinical project manager jobs are remote?
About 67% of senior clinical project manager openings are fully remote or hybrid as of September 2026, reflecting a post-pandemic shift in how sponsors and CROs structure study oversight teams. Roles focused on vendor management, data review, and regulatory coordination tend to offer the most remote flexibility, while positions with heavy site monitoring or startup responsibilities more often require regional travel.
How do you become a senior clinical project manager?
Most senior clinical project managers start as clinical research associates or study coordinators, then move into project management roles where they own full study timelines. From there, accumulating experience across multiple therapeutic areas, leading cross-functional teams, and taking accountability for sponsor or CRO budgets builds the profile most hiring managers look for. Earning a project management certification alongside clinical credentials also strengthens the transition into senior-level positions.
Can you get hired as a senior clinical project manager without senior-level experience?
It's possible if you can demonstrate end-to-end study ownership rather than task-level execution in your current role. Candidates who have led a trial from startup through closeout, managed a CRO relationship independently, or stepped into a project lead role during a staffing gap often compete for senior titles without a formal senior credit on their resume. Framing your application around outcomes and accountability, not just responsibilities, closes that gap.
What does the senior clinical project manager interview process look like?
Most processes run three to five rounds, starting with a recruiter screen focused on therapeutic area fit and systems experience. A hiring manager interview typically follows, centered on behavioral questions about managing protocol deviations, vendor escalations, and timeline recovery. Later rounds often involve a cross-functional panel with clinical operations, regulatory, or data management leads, and some sponsors ask candidates to walk through a mock risk mitigation plan or study startup scenario.
Where can I find and apply to senior clinical project manager jobs?
You can find and apply to senior clinical project manager jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your therapeutic background and study experience, then apply directly to each listing.
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