Senior Clinical Project Manager Jobs
Senior Clinical Project Manager jobs are open across pharmaceutical, biotechnology, medical device, and contract research organizations, from mid-level to executive, with specializations in oncology trials, regulatory affairs, and global study management. Find a role that fits from the openings below and apply directly.
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ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
As a Senior Clinical Project Manager at ICON, you will be responsible for leading and manage projects, ensuring successful execution and delivery of project objectives, including those supporting radiopharmaceutical and radioligand-based clinical programs.
What You Will Do:
You will manage day-to-day project and program management activities, supporting your team to deliver quality outcomes.
Key responsibilities include:
Developing and executing clinical project plans, focusing on achieving project goals and objectives, including those for radiopharmaceutical and radioligand studies with specialized operational requirements.
Leading cross-functional teams to ensure the successful implementation of project activities.
Collaborating with stakeholders to identify project requirements and define project scope.
Mentoring and guiding team members, fostering a culture of excellence and continuous improvement.
Driving the development of project documentation and reports to present findings to stakeholders in a clear and actionable manner.
Staying abreast of industry trends and emerging technologies, including advancements in precision medicine, radiopharmaceuticals, and targeted oncology therapies, to integrate best practices into project management strategies.
Contributing to organizational growth through effective project leadership and strategic planning.
Your Profile:
You will have solid clinical project and program management experience, with the ability to manage competing priorities and develop your team.
Required qualifications and experience:
Bachelor's degree in a relevant scientific discipline or healthcare-related field
Extensive experience in project management, with a proven track record of leading successful projects in the pharmaceutical or biotech industry;
experience in oncology, nuclear medicine, radiopharmaceuticals, or radioligand therapies is strongly preferred
Strong proficiency in project management tools and methodologies, with excellent attention to detail.
Excellent analytical and problem-solving skills, with the ability to develop effective project strategies.
Demonstrated leadership skills, with experience in managing and mentoring teams effectively.
Exceptional communication skills, with the ability to convey technical concepts to diverse audiences.
Detail-oriented, with strong organizational skills to manage multiple projects and deadlines in a dynamic environment.
Willingness to travel as required (approximately 25%)
#LI-MH1
#LI-REMOTE
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request .
Are you a current ICON Employee?
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
As a Senior Clinical Project Manager at ICON, you will be responsible for leading and manage projects, ensuring successful execution and delivery of project objectives, including those supporting radiopharmaceutical and radioligand-based clinical programs.
What You Will Do:
You will manage day-to-day project and program management activities, supporting your team to deliver quality outcomes.
Key responsibilities include:
Developing and executing clinical project plans, focusing on achieving project goals and objectives, including those for radiopharmaceutical and radioligand studies with specialized operational requirements.
Leading cross-functional teams to ensure the successful implementation of project activities.
Collaborating with stakeholders to identify project requirements and define project scope.
Mentoring and guiding team members, fostering a culture of excellence and continuous improvement.
Driving the development of project documentation and reports to present findings to stakeholders in a clear and actionable manner.
Staying abreast of industry trends and emerging technologies, including advancements in precision medicine, radiopharmaceuticals, and targeted oncology therapies, to integrate best practices into project management strategies.
Contributing to organizational growth through effective project leadership and strategic planning.
Your Profile:
You will have solid clinical project and program management experience, with the ability to manage competing priorities and develop your team.
Required qualifications and experience:
Bachelor's degree in a relevant scientific discipline or healthcare-related field
Extensive experience in project management, with a proven track record of leading successful projects in the pharmaceutical or biotech industry;
experience in oncology, nuclear medicine, radiopharmaceuticals, or radioligand therapies is strongly preferred
Strong proficiency in project management tools and methodologies, with excellent attention to detail.
Excellent analytical and problem-solving skills, with the ability to develop effective project strategies.
Demonstrated leadership skills, with experience in managing and mentoring teams effectively.
Exceptional communication skills, with the ability to convey technical concepts to diverse audiences.
Detail-oriented, with strong organizational skills to manage multiple projects and deadlines in a dynamic environment.
Willingness to travel as required (approximately 25%)
#LI-MH1
#LI-REMOTE
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request .
Are you a current ICON Employee?
Senior Clinical Project Manager Jobs by Experience Level
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Find JobsSenior Clinical Project Manager Job Market
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services12
- Education5
- Biotechnology & Pharmaceuticals4
- Science & Research2
- Insurance1
What Employers Look For
The qualifications that appear most often in senior clinical project manager jobs.
- Bachelor's or advanced degree in life sciences, nursing, or a related clinical field
- Minimum five to eight years of clinical trial management experience across multiple phases
- Proficiency with clinical trial management systems such as Veeva Vault or Medidata Rave
- Project Management Professional or equivalent certification preferred by most sponsors
- Deep knowledge of ICH E6 Good Clinical Practice guidelines and FDA regulatory requirements
- Experience managing CROs, budgets, and cross-functional teams on global or multi-site studies
Tips for Your Senior Clinical Project Manager Job Search
Tailor your resume to ICH E6 language
Hiring managers scan for familiarity with ICH E6 Good Clinical Practice guidelines. Use that exact phrasing when describing protocol oversight or monitoring experience, because applicant tracking systems filter for it before a human ever sees your resume.
Highlight cross-functional budget ownership
Senior roles require direct accountability for study budgets, not just cost tracking. Describe specific phases where you owned vendor contracts, managed CRO invoicing, or handled budget variance reporting to show you can lead financial decisions, not just report them.
Apply early to roles that fit
Migrate Mate lists senior clinical project manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Filter by therapeutic area before applying
Oncology, rare disease, and neuroscience trials each have distinct regulatory timelines and site management demands. Targeting openings that match your therapeutic background makes your application more credible and shortens the ramp-up conversation in interviews.
Prepare a study startup timeline case study
Interviewers at senior level routinely ask you to walk through a complex startup scenario. Have a real example ready that covers site selection, IRB submission timelines, and enrollment delays, and be specific about what you controlled versus escalated.
Negotiate scope before title when switching sponsors
Moving from a CRO to a sponsor, or vice versa, often resets perceived seniority. Before accepting an offer, clarify study portfolio size, number of direct reports, and global versus regional scope, because those determine your actual leverage in future negotiations more than the title does.
Senior Clinical Project Manager Jobs: Frequently Asked Questions
Which companies are hiring the most senior clinical project managers?
The companies hiring the most senior clinical project managers right now include Unified Women’s Healthcare, Abbott, and PIH Health, with the largest share of openings in California, North Carolina, and New York, based on current listings on Migrate Mate as of August 2026. Pharmaceutical sponsors and large CROs consistently account for the highest volume of active postings.
How many senior clinical project manager jobs are remote?
About 46% of senior clinical project manager openings are fully remote or hybrid as of August 2026, reflecting a post-pandemic shift in how sponsors and CROs structure study oversight teams. Roles focused on vendor management, data review, and regulatory coordination tend to offer the most remote flexibility, while positions with heavy site monitoring or startup responsibilities more often require regional travel.
How do you become a senior clinical project manager?
Most senior clinical project managers start as clinical research associates or study coordinators, then move into project management roles where they own full study timelines. From there, accumulating experience across multiple therapeutic areas, leading cross-functional teams, and taking accountability for sponsor or CRO budgets builds the profile most hiring managers look for. Earning a project management certification alongside clinical credentials also strengthens the transition into senior-level positions.
Can you get hired as a senior clinical project manager without senior-level experience?
It's possible if you can demonstrate end-to-end study ownership rather than task-level execution in your current role. Candidates who have led a trial from startup through closeout, managed a CRO relationship independently, or stepped into a project lead role during a staffing gap often compete for senior titles without a formal senior credit on their resume. Framing your application around outcomes and accountability, not just responsibilities, closes that gap.
What does the senior clinical project manager interview process look like?
Most processes run three to five rounds, starting with a recruiter screen focused on therapeutic area fit and systems experience. A hiring manager interview typically follows, centered on behavioral questions about managing protocol deviations, vendor escalations, and timeline recovery. Later rounds often involve a cross-functional panel with clinical operations, regulatory, or data management leads, and some sponsors ask candidates to walk through a mock risk mitigation plan or study startup scenario.
Where can I find and apply to senior clinical project manager jobs?
You can find and apply to senior clinical project manager jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your therapeutic background and study experience, then apply directly to each listing.
See All 77 Senior Clinical Project Manager Jobs
Find roles that match your experience and apply in just a few clicks.
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