Mid Level Senior Clinical Trial Manager Jobs
Mid level senior clinical trial manager jobs go to professionals ready to own protocol execution, coordinate cross-functional teams, and resolve site-level challenges with minimal oversight. 31% of openings are remote or hybrid, concentrated in Biotechnology & Pharmaceuticals, Healthcare & Medical Services, and Science & Research, with Medpace, Iqvia, and Moderna hiring at this level now.
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You’ve done this before — now do it with more ownership. You’ll run the TMF for your studies end-to-end, work directly with CROs to resolve problems before they become problems, and help the CTAs around you get better at the job.
Position Description
You’ll independently own key operational pieces of our trials — from TMF integrity to vendor coordination — and mentor junior team members along the way.
The Opportunity
- Own the study TMF plan end-to-end: development, tracking, and archiving of Essential Documents across the trial lifecycle
- Lead quality reviews of the TMF and resolve discrepancies directly with the CRO
- Draft and finalize study documents — plans, manuals, CRFs, and patient materials — with minimal oversight
- Serve as a go-to resource for junior CTAs, providing informal mentorship and process guidance
- Independently manage clinical supply and lab sample coordination, flagging risks before they escalate
- Own data reconciliation issues across systems, looping in Data Management only when needed
- Represent Clinical Operations at portions of team meetings and Investigator Meetings
- Help shape training materials and SOPs used across the broader CTA team
What You’ll Bring
- Bachelor’s degree (BS/BA) or equivalent combination of education and work experience in a science-related field
- 3–5+ years of Clinical Operations or clinical research-related experience
- Demonstrated ownership of a TMF or vendor relationship from start to finish
- Comfortable resolving routine CRO/vendor issues independently before escalating
- Experience mentoring or informally guiding junior team members
- Excellent verbal and written communication skills
- Proficiency with MS Word, Excel, Outlook, and PowerPoint
Salary Range: $134,500 - $146,600 annually
The posted range applies to roles based in the San Francisco Bay Area and reflects local market conditions. Where an offer lands within that range depends on the candidate’s relevant experience, technical expertise, and how their background aligns with the role’s requirements.
Location: Onsite - Brisbane, CA
Fit with Nurix Culture and Values
- Strong team orientation; highly collaborative
- Solutions and results-oriented focus
- Hands-on approach; resourceful and open to diverse points of view
About Nurix Therapeutics
Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.
You’ve done this before — now do it with more ownership. You’ll run the TMF for your studies end-to-end, work directly with CROs to resolve problems before they become problems, and help the CTAs around you get better at the job.
Position Description
You’ll independently own key operational pieces of our trials — from TMF integrity to vendor coordination — and mentor junior team members along the way.
The Opportunity
- Own the study TMF plan end-to-end: development, tracking, and archiving of Essential Documents across the trial lifecycle
- Lead quality reviews of the TMF and resolve discrepancies directly with the CRO
- Draft and finalize study documents — plans, manuals, CRFs, and patient materials — with minimal oversight
- Serve as a go-to resource for junior CTAs, providing informal mentorship and process guidance
- Independently manage clinical supply and lab sample coordination, flagging risks before they escalate
- Own data reconciliation issues across systems, looping in Data Management only when needed
- Represent Clinical Operations at portions of team meetings and Investigator Meetings
- Help shape training materials and SOPs used across the broader CTA team
What You’ll Bring
- Bachelor’s degree (BS/BA) or equivalent combination of education and work experience in a science-related field
- 3–5+ years of Clinical Operations or clinical research-related experience
- Demonstrated ownership of a TMF or vendor relationship from start to finish
- Comfortable resolving routine CRO/vendor issues independently before escalating
- Experience mentoring or informally guiding junior team members
- Excellent verbal and written communication skills
- Proficiency with MS Word, Excel, Outlook, and PowerPoint
Salary Range: $134,500 - $146,600 annually
The posted range applies to roles based in the San Francisco Bay Area and reflects local market conditions. Where an offer lands within that range depends on the candidate’s relevant experience, technical expertise, and how their background aligns with the role’s requirements.
Location: Onsite - Brisbane, CA
Fit with Nurix Culture and Values
- Strong team orientation; highly collaborative
- Solutions and results-oriented focus
- Hands-on approach; resourceful and open to diverse points of view
About Nurix Therapeutics
Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.
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Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Healthcare & Medical Services
- Science & Research
- Technology & Software
- Consulting & Professional Services
Mid Level Senior Clinical Trial Manager Jobs: Frequently Asked Questions
How do I get a mid level senior clinical trial manager job?
Position yourself as someone who has moved beyond execution into ownership. Highlight experience managing study timelines, vendor relationships, or site escalations independently. Emphasize protocol deviations you resolved, budgets you tracked, and cross-functional teams you coordinated. Tailor your application to show that you drive trial progress without waiting for direction, and quantify your impact wherever possible.
Which companies hire mid level senior clinical trial managers?
Companies hiring mid level senior clinical trial managers right now include Medpace, Iqvia, and Moderna, based on current listings on Migrate Mate as of September 2026. Hiring at this level comes from a mix of large pharmaceutical companies, mid-size contract research organizations, and emerging biotech sponsors building out their clinical operations teams.
Are there remote mid level senior clinical trial manager jobs?
Yes, though availability varies by sponsor and study phase. About 31% of mid level senior clinical trial manager openings are remote or hybrid as of September 2026, reflecting how much of the coordination work can be handled without being on site. Roles tied to active site visits or sponsor headquarters tend to require more in-person presence.
How do I move up to a mid level senior clinical trial manager role?
Growth from entry level into mid level comes from accumulating ownership, not just exposure. Early-career clinical trial professionals should seek roles where they manage site relationships directly, take lead on protocol training, and handle deviation documentation without heavy supervision. Demonstrating consistent delivery across multiple studies and building cross-functional communication skills accelerates the transition into mid level responsibility.
Which industries hire the most mid level senior clinical trial managers?
Mid Level senior clinical trial manager roles concentrate in Biotechnology & Pharmaceuticals, Healthcare & Medical Services, and Science & Research, based on current listings on Migrate Mate as of September 2026. Those sectors drive the most hiring because they operate ongoing pipeline development that requires experienced trial managers who can run studies with limited escalation to senior leadership.