Senior Clinical Trial Manager Jobs in South Dakota

Senior Clinical Trial Manager jobs in South Dakota are open across Sioux Falls, Pierre, and Sd and other South Dakota metros, with employers like CVS Health, Sanford Health, and Affirm hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles52+
Top employerCVS Health
Top citySioux Falls, SD
Cities hiring9
Work type75% On-site
Top industryHealthcare

Showing 5 of 52+ Senior Clinical Trial Manager jobs

Ryder System
Senior Manager Environmental Engineer
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Ryder System
Added 1mo ago
Senior Manager Environmental Engineer
Ryder System
Pierre, South Dakota
Specialized Engineering
Project & Program Management
Compliance & Legal
Environmental Engineering
Project Management
Compliance & Risk
$140k - $160k/yr
On-Site
Bachelor's

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Affirm
Senior Manager, Software Engineering
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Affirm
Added 3mo ago
Senior Manager, Software Engineering
Affirm
Sioux Falls, South Dakota
Software Engineering
Technical Product & Program Management
Data Engineering
Technical Program Management
Backend Engineering
$232k - $310k/yr
Hybrid
Bachelor's

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Affirm
Senior Manager, Software Engineering
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Affirm
Added 6mo ago
Senior Manager, Software Engineering
Affirm
Sioux Falls, South Dakota
Software Engineering
Technical Program Management
Cloud Engineering
Backend Engineering
Hybrid
Bachelor's

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Affirm
Senior Manager, Software Engineering
We won't show you this job again
Affirm
Added 6mo ago
Senior Manager, Software Engineering
Affirm
Sioux Falls, South Dakota
Software Engineering
Technical Program Management
Cloud Engineering
Backend Engineering
Hybrid
Bachelor's

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CVS Health
Senior Manager, Provider NPS Enablement
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CVS Health
Added 2d ago
Senior Manager, Provider NPS Enablement
CVS Health
Pierre, South Dakota
Project & Program Management
Strategy & Corporate Development
Customer Success
Project Management
Program Management
Business Strategy
$68k - $199k/yr
Hybrid
Bachelor's
10,000+

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See All 52 Senior Clinical Trial Manager Jobs in South Dakota

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Senior Clinical Trial Manager Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Sioux Falls
30 jobs
Pierre
12 jobs
Sd
2 jobs
Tyndall
2 jobs
Watertown
2 jobs
Aberdeen
1 jobs
Minnehaha County
1 jobs
Rapid City
1 jobs
Vermillion
1 jobs

Senior Clinical Trial Manager Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

  • CVS Health
    CVS Health8
  • Sanford Health
    Sanford Health8
  • Affirm
    Affirm6
  • CNH Industrial
    CNH Industrial4
  • Ryder System
    Ryder System3

Top Industries Hiring

  • Healthcare & Medical Services19
  • Manufacturing8
  • Banking & Financial Services7
  • Fintech3
  • Technology & Software3

What South Dakota Employers Look For

The qualifications that appear most often in senior clinical trial manager jobs across South Dakota.

  • Bachelor's or advanced degree in life sciences, nursing, or a related clinical field
  • Minimum five to eight years of clinical trial management experience across multiple phases
  • Direct site management experience in Phase II or Phase III oncology or specialty therapeutic areas
  • Proficiency in electronic data capture systems such as Medidata Rave or Oracle Clinical
  • Demonstrated knowledge of ICH E6 Good Clinical Practice guidelines and FDA regulations
  • Project Management Professional or equivalent clinical research certification such as CCRA or CCRC

Senior Clinical Trial Manager Jobs in South Dakota: Frequently Asked Questions

How many senior clinical trial manager jobs are there in South Dakota?

There are 52+ senior clinical trial manager openings in South Dakota on Migrate Mate as of June 2026, with the most roles in Sioux Falls, Pierre, and Sd. New positions post regularly as employers across South Dakota hire.

Which South Dakota cities have the most senior clinical trial manager jobs?

Sioux Falls, Pierre, and Sd have the most senior clinical trial manager openings in South Dakota right now, with additional roles spread across smaller metros statewide.

Which companies hire senior clinical trial managers in South Dakota?

Employers hiring senior clinical trial managers in South Dakota include CVS Health, Sanford Health, and Affirm, based on current listings on Migrate Mate as of June 2026.

Are there remote senior clinical trial manager jobs in South Dakota?

Yes. About 25% of senior clinical trial manager openings tied to South Dakota are remote or hybrid as of June 2026. The rest are on-site roles based in South Dakota metros.

How do I apply for senior clinical trial manager jobs in South Dakota?

You can apply to senior clinical trial manager jobs in South Dakota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Dakota location, then apply to each one that fits.

See All 52 Senior Clinical Trial Manager Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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