Registered Nurse Jobs in South Dakota
Registered Nurse jobs in South Dakota are concentrated in acute care hospitals, long-term care facilities, and rural health clinics, with demand steady at every level from new graduate to experienced charge nurse. The largest hiring activity is in Sioux Falls, Rapid City, and Aberdeen, where systems like Sanford Health, Avera Health, and Monument Health anchor the market. Critical care, med-surg, and emergency nursing see the most consistent openings across the state. See the openings below and apply to the ones that match your experience.
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At RestorixHealth, our mission is simple…to restore health and improve the quality of life – and access to care – for patients with wounds.
The Full Time Clinical Nurse Coordinator is a dual role consisting of Registered Nurse and Marketing Coordinator.
The Registered Nurse (RN) provides direct patient care and coordination of care for patients through assessment and team collaboration in evaluation, planning and implementing evidence based holistic wound care. The Marketing Coordinator is responsible for developing and maintaining community relationships with current and future referral sources through direct referral source interaction and education of medical communities on services provided and patient eligibility.
The ideal Nurse Coordinator is flexible and cooperative in fulfilling role obligations, and willing to continue coordination of care efforts even during non-clinical hours. The Nurse Coordinator will receive ongoing training and will be provided with additional resources to help you be successful in your role.
Take your passion for enhancing the lives of patients and turn it into a career, join the RestorixHealth Team and APPLY TODAY!
What We Offer:
- Monday - Friday schedule, no weekends
- RestorixHealth is proud to provide employees with a comprehensive and attractive benefits program which includes the following:
- Medical, Dental and Vision Insurance
- Health Savings Account (with employer match) and Flexible Spending Accounts (General Purpose, Limited Purpose and Dependent Care)
- Employer-Paid Basic Life Insurance, AD&D and Short-Term Disability
- Voluntary Buy-Up Life Insurance (for self, spouse & children), Short-Term Disability and Long-Term Disability
- Voluntary Accident, Critical Illness and Hospital Indemnity Plans
- Employee Assistance Program
- Pet Care Discount Program
- Generous Paid Time Off and Paid Holidays
- 401(k) Retirement Plan (with employer match)
- Internal ongoing educational/training opportunities
- Competitive compensation
- Continuous coaching & mentorship
- Ensure staff demonstrates competency in core and center-specific clinical skills, and that continuing education and certificates are maintained and up to date
- Review wound healing center activities and recommend process flow changes in, or better utilization of, facilities, services, and staff
- Establishes weekly contacts with host facilities’ administration and medical staff. Adheres to our and host facility regulatory and accrediting standards policies/procedures
- Maintains open communication with Senior Management, Regional Director, Program Director, Clinical Team, host facility staff, providers, and business office staff to ensure continuity of care
- Actively participates in all Quality Management measures, and ensures all measures are turned in by designated deadlines
- Develops patient specific wound care plan and regularly reviews wound progress. Follows up with lab and diagnostic results, communicates to provider and patient, and documents accurately
- Ensures accuracy, legibility, and completion of all staff documentation and adheres to daily chart check and correction policy
- Valid Registered Nurse license in the state of employment
- Current BLS and ACLS certification through the American Heart Association
- Minimum of 3 years of nursing experience, wound care clinic experience or a combination of both
- Ability to function competently and independently to provide the highest quality of nursing practice
RestorixHealth is an Equal Opportunity Employer encouraging diversity in the workplace. All qualified applicants will receive consideration for employment without regard to race, national origin, gender, age, religion, disability, sexual orientation, veteran status, or marital status.
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Find Registered Nurse JobsRegistered Nurse Jobs by City in South Dakota
Where South Dakota roles are concentrated, by current openings.
Registered Nurse Job Market in South Dakota
A snapshot from current South Dakota openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Technology & Software
What South Dakota Employers Look For
The qualifications that appear most often in registered nurse jobs across South Dakota.
- Active registered nurse license issued or recognized by the South Dakota Board of Nursing
- Associate or bachelor of science in nursing degree from an accredited program
- Current BLS certification and ACLS certification for most acute care positions
- Minimum one to two years of clinical nursing experience for specialty unit roles
- Proficiency with electronic health record systems such as Epic or Cerner
- Strong assessment, documentation, and patient communication skills in a clinical setting
Registered Nurse Jobs in South Dakota: Frequently Asked Questions
How do you become a registered nurse in South Dakota?
You must earn an associate or bachelor of science in nursing from an accredited program, pass the NCLEX-RN examination, and obtain an active license through the South Dakota Board of Nursing. South Dakota is a member of the Nurse Licensure Compact, so nurses already licensed in another compact state can work in South Dakota without obtaining a separate state license, though you must meet compact requirements.
How much do registered nurses make in South Dakota?
Registered nurses in South Dakota earn a median of about $78,060 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $54,040 for the lowest 10% to over $98,220 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire registered nurses in South Dakota?
South Dakota registered nurse roles are posted by Monument Health, Horizon Health, and RestorixHealth and others right now, based on current listings on Migrate Mate as of August 2026. Sanford Health and Avera Health are the two largest health systems in the state and consistently represent a significant share of total registered nurse openings across South Dakota.
Which South Dakota cities have the most registered nurse jobs?
Sioux Falls, Custer, and Eureka have the most registered nurse openings in South Dakota. Sioux Falls drives the highest volume as the state's largest city and home to Sanford Health and Avera McKennan, while Rapid City generates strong demand through Monument Health, and Aberdeen and Watertown see steady openings tied to regional Avera and Sanford affiliate hospitals serving surrounding rural communities.
How can I get hired as a registered nurse in South Dakota with little or no experience?
The most realistic entry path is a new graduate nurse residency program, which Sanford Health and Avera Health both offer at multiple South Dakota facilities to help new nurses transition from school to independent practice. Applying to med-surg or long-term care units gives candidates the broadest openings, and completing clinical rotations at a South Dakota facility during your nursing program builds a direct relationship with hiring managers before graduation.
Where can I find and apply to registered nurse jobs in South Dakota?
You can find and apply to registered nurse jobs in South Dakota on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the listings to find roles that match your experience level, specialty, and preferred location, then apply directly to the ones that fit.
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