Registered Nurse Jobs in South Dakota

Registered Nurse jobs in South Dakota are concentrated in acute care hospitals, long-term care facilities, and rural health clinics, with demand steady at every level from new graduate to experienced charge nurse. The largest hiring activity is in Sioux Falls, Rapid City, and Aberdeen, where systems like Sanford Health, Avera Health, and Monument Health anchor the market. Critical care, med-surg, and emergency nursing see the most consistent openings across the state. See the openings below and apply to the ones that match your experience.

Find Registered Nurse Jobs

Overview

Open roles13
Top employerAmerican Traveler
Top citySioux Falls, SD
Cities hiring6
Work type100% On-site
Top industryHealthcare

Showing 5 of 13+ Registered Nurse jobs

Part time RN Nursing Position
We won't show you this job again
New 23h ago
Part time RN Nursing Position
Stay Graceful
Rapid City, South Dakota
Healthcare Administration
Patient Services & Wellbeing
Public Health

Have you applied for this role?

Registered Nurse (RN - I or RN - III)|Gregory Hospital|PRN
We won't show you this job again
Added 1d ago
Registered Nurse (RN - I or RN - III)|Gregory Hospital|PRN
Avera Health
Gregory, South Dakota
Healthcare Administration
Patient Services & Wellbeing
Public Health
$27.75 - $48.5/hr
10,000+

Have you applied for this role?

Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Hematology & Bone Marrow Transplant Clinic
We won't show you this job again
Added 1d ago
Registered Nurse (RN) or Licensed Practical Nurse (LPN) | Hematology & Bone Marrow Transplant Clinic
Avera Health
Sioux Falls, South Dakota
Healthcare Administration
Nursing
Patient Services & Wellbeing
$22.5 - $41.25/hr
10,000+

Have you applied for this role?

RN
We won't show you this job again
Added 3d ago
RN
Monument Health
Rapid City, South Dakota
Nursing
Healthcare Administration
Patient Services & Wellbeing
$29 - $37/hr
On-Site
Bachelor's

Have you applied for this role?

Travel RN - Med/Surg - Long Term Care
We won't show you this job again
Added 3d ago
Travel RN - Med/Surg - Long Term Care
American Traveler
Aberdeen, South Dakota
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
501-1,000

Have you applied for this role?

See All 13 Registered Nurse Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

Find Registered Nurse Jobs

Registered Nurse Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Sioux Falls
5 jobs
Rapid City
4 jobs
Pierre
1 job
Gregory
1 job
Yankton
1 job
Aberdeen
1 job

Registered Nurse Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

American Traveler4 open roles
Avera Health3 open roles
Monument Health2 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Dakota Employers Look For

The qualifications that appear most often in registered nurse jobs across South Dakota.

  • Active registered nurse license issued or recognized by the South Dakota Board of Nursing
  • Associate or bachelor of science in nursing degree from an accredited program
  • Current BLS certification and ACLS certification for most acute care positions
  • Minimum one to two years of clinical nursing experience for specialty unit roles
  • Proficiency with electronic health record systems such as Epic or Cerner
  • Strong assessment, documentation, and patient communication skills in a clinical setting

Registered Nurse Jobs in South Dakota: Frequently Asked Questions

How do you become a registered nurse in South Dakota?

You must earn an associate or bachelor of science in nursing from an accredited program, pass the NCLEX-RN examination, and obtain an active license through the South Dakota Board of Nursing. South Dakota is a member of the Nurse Licensure Compact, so nurses already licensed in another compact state can work in South Dakota without obtaining a separate state license, though you must meet compact requirements.

How much do registered nurses make in South Dakota?

Registered nurses in South Dakota earn a median of about $78,060 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $54,040 for the lowest 10% to over $98,220 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire registered nurses in South Dakota?

South Dakota registered nurse roles are posted by American Traveler, Avera Health, and Monument Health and others right now, based on current listings on Migrate Mate as of October 2026. Sanford Health and Avera Health are the two largest health systems in the state and consistently represent a significant share of total registered nurse openings across South Dakota.

Which South Dakota cities have the most registered nurse jobs?

Sioux Falls, Rapid City, and Pierre have the most registered nurse openings in South Dakota. Sioux Falls drives the highest volume as the state's largest city and home to Sanford Health and Avera McKennan, while Rapid City generates strong demand through Monument Health, and Aberdeen and Watertown see steady openings tied to regional Avera and Sanford affiliate hospitals serving surrounding rural communities.

Are there remote registered nurse jobs in South Dakota?

Yes, but they're rare. About 0% of registered nurse openings tied to South Dakota are remote or hybrid as of October 2026, reflecting how hands-on clinical care limits remote arrangements for most roles. The positions most likely to allow remote work are telephonic triage nursing, utilization review, and case management roles that do not require direct bedside patient contact.

How can I get hired as a registered nurse in South Dakota with little or no experience?

The most realistic entry path is a new graduate nurse residency program, which Sanford Health and Avera Health both offer at multiple South Dakota facilities to help new nurses transition from school to independent practice. Applying to med-surg or long-term care units gives candidates the broadest openings, and completing clinical rotations at a South Dakota facility during your nursing program builds a direct relationship with hiring managers before graduation.

Where can I find and apply to registered nurse jobs in South Dakota?

You can find and apply to registered nurse jobs in South Dakota on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the listings to find roles that match your experience level, specialty, and preferred location, then apply directly to the ones that fit.

See All 13 Registered Nurse Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

Find Registered Nurse Jobs