Clinical Operations Manager Jobs in South Dakota

Clinical Operations Manager jobs in South Dakota are open across Rapid City, Sioux Falls, and Aberdeen and other South Dakota metros, with employers like Monument Health, Sanford Health, and Sioux Center Health hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles90+
Top employerMonument Health
Top cityRapid City, SD
Cities hiring22
Work type100% On-site
Top industryHealthcare

Showing 5 of 90+ Clinical Operations Manager jobs

Monument Health
Respiratory Care Clinical Quality Educator
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Monument Health
New 2h ago
Respiratory Care Clinical Quality Educator
Monument Health
Rapid City, South Dakota
Healthcare Administration
Clinical Support
Corporate Training & Learning Development
Learning & Development
$33 - $42/hr
On-Site
Associate's

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Monument Health
Clinical Research Registered Nurse
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Monument Health
Added 3d ago
Clinical Research Registered Nurse
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
$32 - $40/hr
On-Site
Bachelor's

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Monument Health
Clinical Resource Nurse
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Monument Health
Added 3d ago
Clinical Resource Nurse
Monument Health
Rapid City, South Dakota
Nursing
Healthcare Administration
Patient Services & Wellbeing
$37 - $46/hr
On-Site
Bachelor's

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Monument Health
Clinical Assistant or Medical Assistant
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Monument Health
Added 5d ago
Clinical Assistant or Medical Assistant
Monument Health
Rapid City, South Dakota
Nursing
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$16 - $23/hr
On-Site
High School

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Monument Health
Pharmacist Clinical
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Monument Health
Added 6d ago
Pharmacist Clinical
Monument Health
Rapid City, South Dakota
Allied Health
Healthcare Administration
Clinical Support
Pharmacy
On-Site
Bachelor's

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See All 90 Clinical Operations Manager Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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Clinical Operations Manager Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Rapid City
29 jobs
Sioux Falls
26 jobs
Aberdeen
5 jobs
Spearfish
4 jobs
Custer
3 jobs
Parkston
3 jobs
Sd
3 jobs
Mitchell
2 jobs
Pierre
2 jobs

Clinical Operations Manager Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

  • Monument Health
    Monument Health30
  • Sanford Health
    Sanford Health28
  • Sioux Center Health
    Sioux Center Health15
  • Sanford Bismarck
    Sanford Bismarck5
  • NVA
    NVA4

Top Industries Hiring

  • Healthcare & Medical Services80
  • Non-Profit & Social Services5
  • Animal Care & Pet Services4
  • Agriculture & Farming3
  • Science & Research1

What South Dakota Employers Look For

The qualifications that appear most often in clinical operations manager jobs across South Dakota.

  • Bachelor's degree in life sciences, nursing, or a related clinical field
  • Minimum five years of clinical trial or clinical operations experience
  • Proficiency with clinical trial management systems such as Veeva or Medidata
  • Strong working knowledge of ICH-GCP guidelines and FDA regulations
  • Experience managing CROs, vendors, or multi-site study teams
  • Project Management Professional or equivalent certification preferred

Clinical Operations Manager Jobs in South Dakota: Frequently Asked Questions

How many clinical operations manager jobs are there in South Dakota?

There are 90+ clinical operations manager openings in South Dakota on Migrate Mate as of June 2026, with the most roles in Rapid City, Sioux Falls, and Aberdeen. New positions post regularly as employers across South Dakota hire.

Which South Dakota cities have the most clinical operations manager jobs?

Rapid City, Sioux Falls, and Aberdeen have the most clinical operations manager openings in South Dakota right now, with additional roles spread across smaller metros statewide.

Which companies hire clinical operations managers in South Dakota?

Employers hiring clinical operations managers in South Dakota include Monument Health, Sanford Health, and Sioux Center Health, based on current listings on Migrate Mate as of June 2026.

Are there remote clinical operations manager jobs in South Dakota?

Yes. About 0% of clinical operations manager openings tied to South Dakota are remote or hybrid as of June 2026. The rest are on-site roles based in South Dakota metros.

How do I apply for clinical operations manager jobs in South Dakota?

You can apply to clinical operations manager jobs in South Dakota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Dakota location, then apply to each one that fits.

See All 90 Clinical Operations Manager Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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