Clinical Operations Manager Jobs in New York
Clinical Operations Manager jobs in New York are among the most active in the country, concentrated in hospital systems, pharmaceutical research, contract research organizations, and health plan administration at every level from team lead to senior director. The largest concentrations of hiring are in New York City, White Plains, and Melville, with major employers such as NYU Langone Health, Northwell Health, and Pfizer maintaining consistent demand for this role. Regulatory affairs coordination, clinical trial management, and quality and compliance oversight are the most sought-after specializations in New York listings. See the openings below and apply to the ones that match your experience.
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Showing 5 of 33+ Clinical Operations Manager jobs
INTRODUCTION
PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life’s moments for children and adults living with a rare disease. At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.
JOB DESCRIPTION SUMMARY
The Associate Director, Clinical Operations provides the scientific and operational expertise required to lead the execution of the complete life cycle of clinical trials in accordance with appropriate regulatory requirements for one or more indications within or across therapeutic areas. The incumbent works as an integrated member of the clinical team to manage clinical trial(s) from study design through close out. The Associate Director, Clinical Operations may manage direct report(s). The incumbent works cross-functionally with internal departments and external resources on Clinical Operations related issues. The Associate Director, Clinical Operations supports adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.
ESSENTIAL FUNCTIONS
Primary Duties/responsibilities
- Performs as an integrated member of the clinical team to lead, direct and contribute to, the planning, execution, and reporting of clinical trials, including estimation of clinical project timelines, protocol writing, Case Report Form (CRF) design, site selection, study drug forecasting, site and Clinical Research Organization (CRO) management, data review, and study reporting; recommends monitoring, safety, eligibility, enrollment, and data consistency strategies.
- Interacts with external and internal project team members to assist in the development of clinical strategies, trial design, study plans, and project deliverables; meets with investigators and PTC scientific and clinical staff to obtain direction and feedback.
- Assists in the evaluation of scientific literature and investigator advice regarding current clinical practice as a component of clinical strategy and protocol development; writes, reviews and/or edits study protocols, protocol amendments, study manuals, informed consent forms, and related documents.
- Prepares investigational site lists and participates in the review and approval of investigational sites; negotiates contracts and budgets with sites and vendors and presents to the project team for approval; plans, coordinates, and conducts investigator meetings including presentations at the meetings; responds to questions from sites and trial monitors regarding trial conduct.
- Manages clinical study timelines using the appropriate project management tools; develops budgets and manages expenditures for clinical trial program, including those for investigational sites and vendors; presents project progress reports through accurate, succinct summaries of clinical study work at internal team meetings and investigator meetings.
- Facilitates regulatory submissions and communications by working with appropriate team members during the submission process; writes assigned portions of reports for submission to regulatory agencies, institutional review boards, scientific journals, and conferences.
- Provides ongoing review of clinical trial data to ensure timely, consistent, and accurate data; assists in the interpretation of clinical data in preparation for clinical study reports and regulatory submissions.
- Manages, coaches and mentors direct reports.
KNOWLEDGE/SKILLS/ABILITIES REQUIRED
- Bachelor’s degree in a scientific discipline and a minimum of 7 years progressively responsible US and/or global experience in clinical research in a pharmaceutical, biotechnology, CRO, university medical center or related environment.
- Comprehensive working knowledge of the drug developmental process.
- Working knowledge of clinical trial design, conduct, data acquisition, and reporting.
- Ability to recognize safety and efficacy trends of clinical data.
- Hands-on experience supporting and understanding Good Manufacturing Practice (GMP), Good Clinical Practice (GCP), and International Conference on Harmonisation (ICH) guidelines.
- Ability to influence without direct authority.
- Proficiency with Microsoft Word and Excel.
- Excellent verbal and written communication skills.
- Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members.
- Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
- Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.
PREFERRED QUALIFICATIONS
- Prior involvement in Investigational New Drug applications (INDs) and New Drug Applications (NDAs) submissions.
- Previous experience as a field monitor.
- Medical writing experience or training.
- Proficiency with Microsoft Project and PowerPoint.
- People and project management experience.
TRAVEL REQUIREMENTS
- Up to 20%
EXPECTED BASE SALARY RANGE
$170,200 - $214,200. The base salary offered will be contingent on assessment of candidate education level, background, and experience relative to the requirements of the position they are being considered for, as well as review of internal equity. In addition to base salary, PTC employees are also eligible for short- and long-term incentives. All eligible employees may also enroll in PTC’s medical, dental, vision, and retirement savings plans.
EEO STATEMENT
PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.
INTRODUCTION
PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life’s moments for children and adults living with a rare disease. At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.
JOB DESCRIPTION SUMMARY
The Associate Director, Clinical Operations provides the scientific and operational expertise required to lead the execution of the complete life cycle of clinical trials in accordance with appropriate regulatory requirements for one or more indications within or across therapeutic areas. The incumbent works as an integrated member of the clinical team to manage clinical trial(s) from study design through close out. The Associate Director, Clinical Operations may manage direct report(s). The incumbent works cross-functionally with internal departments and external resources on Clinical Operations related issues. The Associate Director, Clinical Operations supports adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.
ESSENTIAL FUNCTIONS
Primary Duties/responsibilities
- Performs as an integrated member of the clinical team to lead, direct and contribute to, the planning, execution, and reporting of clinical trials, including estimation of clinical project timelines, protocol writing, Case Report Form (CRF) design, site selection, study drug forecasting, site and Clinical Research Organization (CRO) management, data review, and study reporting; recommends monitoring, safety, eligibility, enrollment, and data consistency strategies.
- Interacts with external and internal project team members to assist in the development of clinical strategies, trial design, study plans, and project deliverables; meets with investigators and PTC scientific and clinical staff to obtain direction and feedback.
- Assists in the evaluation of scientific literature and investigator advice regarding current clinical practice as a component of clinical strategy and protocol development; writes, reviews and/or edits study protocols, protocol amendments, study manuals, informed consent forms, and related documents.
- Prepares investigational site lists and participates in the review and approval of investigational sites; negotiates contracts and budgets with sites and vendors and presents to the project team for approval; plans, coordinates, and conducts investigator meetings including presentations at the meetings; responds to questions from sites and trial monitors regarding trial conduct.
- Manages clinical study timelines using the appropriate project management tools; develops budgets and manages expenditures for clinical trial program, including those for investigational sites and vendors; presents project progress reports through accurate, succinct summaries of clinical study work at internal team meetings and investigator meetings.
- Facilitates regulatory submissions and communications by working with appropriate team members during the submission process; writes assigned portions of reports for submission to regulatory agencies, institutional review boards, scientific journals, and conferences.
- Provides ongoing review of clinical trial data to ensure timely, consistent, and accurate data; assists in the interpretation of clinical data in preparation for clinical study reports and regulatory submissions.
- Manages, coaches and mentors direct reports.
KNOWLEDGE/SKILLS/ABILITIES REQUIRED
- Bachelor’s degree in a scientific discipline and a minimum of 7 years progressively responsible US and/or global experience in clinical research in a pharmaceutical, biotechnology, CRO, university medical center or related environment.
- Comprehensive working knowledge of the drug developmental process.
- Working knowledge of clinical trial design, conduct, data acquisition, and reporting.
- Ability to recognize safety and efficacy trends of clinical data.
- Hands-on experience supporting and understanding Good Manufacturing Practice (GMP), Good Clinical Practice (GCP), and International Conference on Harmonisation (ICH) guidelines.
- Ability to influence without direct authority.
- Proficiency with Microsoft Word and Excel.
- Excellent verbal and written communication skills.
- Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members.
- Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
- Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.
PREFERRED QUALIFICATIONS
- Prior involvement in Investigational New Drug applications (INDs) and New Drug Applications (NDAs) submissions.
- Previous experience as a field monitor.
- Medical writing experience or training.
- Proficiency with Microsoft Project and PowerPoint.
- People and project management experience.
TRAVEL REQUIREMENTS
- Up to 20%
EXPECTED BASE SALARY RANGE
$170,200 - $214,200. The base salary offered will be contingent on assessment of candidate education level, background, and experience relative to the requirements of the position they are being considered for, as well as review of internal equity. In addition to base salary, PTC employees are also eligible for short- and long-term incentives. All eligible employees may also enroll in PTC’s medical, dental, vision, and retirement savings plans.
EEO STATEMENT
PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.
See All 33 Clinical Operations Manager Jobs in New York
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Find JobsClinical Operations Manager Jobs by City in New York
Where New York roles are concentrated, by current openings.
Clinical Operations Manager Job Market in New York
A snapshot from current New York openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
- Education
What New York Employers Look For
The qualifications that appear most often in clinical operations manager jobs across New York.
- Bachelor's degree in health administration, life sciences, nursing, or a related clinical field
- Minimum five years of progressive experience in clinical or healthcare operations settings
- Demonstrated leadership of cross-functional clinical or operations teams in a regulated environment
- Working knowledge of FDA regulations, GCP guidelines, and healthcare compliance standards
- Experience with electronic health records systems and clinical trial management software
- Strong project management skills with ability to oversee multiple concurrent clinical programs
Clinical Operations Manager Jobs in New York: Frequently Asked Questions
How do you become a clinical operations manager in New York?
Most clinical operations managers in New York enter the role after several years in clinical coordination, research administration, or healthcare management, typically holding a bachelor's degree in a health-related field and often a master's in health administration or public health. New York does not require a state license specific to the clinical operations manager title, though roles within licensed facilities may require staff to hold or supervise licensees under the New York State Education Department. Employers frequently prioritize candidates with GCP certification or Project Management Professional credentials.
Which companies hire clinical operations managers in New York?
Employers hiring clinical operations managers in New York right now include Leap, PTC Therapeutics, and University of Rochester, based on current listings on Migrate Mate as of October 2026. New York's dense concentration of academic medical centers, biopharmaceutical headquarters, and large managed care organizations makes it one of the most diverse hiring markets for this role in the country.
Which New York cities have the most clinical operations manager jobs?
New York, Queens, and Brooklyn have the most clinical operations manager openings in New York. New York City drives the largest share of listings because of its concentration of major hospital systems, pharmaceutical company offices, and contract research organizations, while suburban hubs like White Plains and Melville reflect the suburban campuses of large health systems and regional managed care plans that have expanded operations outside Manhattan.
Are there remote clinical operations manager jobs in New York?
Yes, and more than many clinical roles. About 54% of clinical operations manager openings tied to New York are remote or hybrid as of October 2026, reflecting the significant desk-based and coordination work the role involves. Functions such as regulatory document review, vendor oversight, protocol development, and data quality monitoring are the parts of the role most commonly performed remotely, while site-facing or patient-facing responsibilities remain on-site.
How can I get hired as a clinical operations manager in New York with little or no experience?
The most realistic entry path is moving into the role from a clinical coordinator, research coordinator, or operations analyst position at a New York health system or CRO, where internal promotion into management is common. Northwell Health, NYU Langone, and Memorial Sloan Kettering each run structured professional development programs that prepare high-performing coordinators for operations leadership. Earning a Certified Clinical Research Professional credential or completing a health administration graduate certificate strengthens an application significantly for candidates without a management title yet.
Where can I find and apply to clinical operations manager jobs in New York?
You can find and apply to clinical operations manager jobs in New York on Migrate Mate, which lists current openings tied to New York employers and locations. Search the listings to find roles that match your background, then apply directly to the ones that fit your experience level and preferred setting.
See All 33 Clinical Operations Manager Jobs in New York
Find roles in New York that match your experience and apply in just a few clicks.
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