Clinical Operations Manager Jobs in California

Clinical Operations Manager jobs in California are among the most active in the country, concentrated in biotech and pharmaceutical companies, large academic medical centers, and health system networks, with openings at every level from junior coordinators stepping into management to senior directors overseeing multi-site trials. The biggest hiring centers are San Francisco Bay Area, Los Angeles, and San Diego, where employers like Kaiser Permanente, Genentech, and UCLA Health maintain deep, ongoing demand. The most sought-after specialties are clinical trial operations, care delivery optimization, and cross-functional program management within regulated research environments. Find a role that fits below and apply directly.

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Overview

Open roles77
Top employerRevolution Medicines
Top cityRedwood City, CA
Cities hiring30
Work type61% On-site
Top industryBiotechnology

Showing 5 of 77+ Clinical Operations Manager jobs

Executive Director Clinical Operations, Humboldt
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New 6h ago
Executive Director Clinical Operations, Humboldt
Providence
Santa Rosa, California
Business Strategy
Corporate Development & M&A
Growth Marketing
$95.99 - $171.6/hr
Master's degree in business administration
10,000+

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Assoc. Manager / Manager, Clinical Operations - FSP
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New 13h ago
Assoc. Manager / Manager, Clinical Operations - FSP
Thermo Fisher Scientific
California
Accounting
Compliance & Risk
Healthcare Administration
$115k - $180k/yr
On-Site
Bachelor's degree
10,000+

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Manager of Clinical Operations (Nurse Practitioner, Physician Assistant)
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New 22h ago
Manager of Clinical Operations (Nurse Practitioner, Physician Assistant)
Woundtech
California
Clinical Support
Healthcare Administration
Public Health
201-500

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Clinical Operations Manager
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New 23h ago
Clinical Operations Manager
Wellmind
Palo Alto, California
Business Operations
Human Resources
Project Management
$115k - $125k/yr
On-Site

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Clinical Operations Manager (ACC)
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Added 3d ago
Clinical Operations Manager (ACC)
American Career College
Los Angeles, California
Clinical Support
Healthcare Administration
Human Resources
$88k.06 - $128k.21/yr
CPR Certification
201-500

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See All 77 Clinical Operations Manager Jobs in California

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Clinical Operations Manager Jobs by City in California

Where California roles are concentrated, by current openings.

Redwood City
13 jobs
San Diego
8 jobs
Los Angeles
7 jobs
San Francisco
6 jobs
South San Francisco
5 jobs
Alameda
3 jobs
Santa Rosa
3 jobs
Irvine
2 jobs
Orange
2 jobs

Clinical Operations Manager Job Market in California

A snapshot from current California openings, updated as new roles post.

Who's Hiring

Revolution Medicines9 open roles
Cedars-Sinai Medical Center4 open roles
Exelixis3 open roles

Top Industries Hiring

  • Biotechnology & Pharmaceuticals11
  • Healthcare & Medical Services2
  • Education1
  • Medical Devices1

What California Employers Look For

The qualifications that appear most often in clinical operations manager jobs across California.

  • Bachelor's degree in life sciences, health administration, or a related clinical field
  • Minimum three to five years of clinical operations or clinical project management experience
  • Demonstrated experience managing cross-functional teams across clinical or research settings
  • Familiarity with FDA regulations, GCP guidelines, and California-specific healthcare compliance requirements
  • Proficiency with clinical trial management systems or electronic health record platforms
  • Strong written and verbal communication skills for stakeholder reporting and regulatory documentation

Clinical Operations Manager Jobs in California: Frequently Asked Questions

How do you become a clinical operations manager in California?

Most clinical operations managers in California build toward the role through a combination of a bachelor's degree in a health sciences or business field and several years in clinical coordination, project management, or research operations. A master's in health administration or public health strengthens candidacy at larger systems and biotech firms. While California does not require a state-issued license specific to this management title, roles embedded in clinical research often expect ICH-GCP training and familiarity with California Department of Public Health regulations governing research sites.

Which companies hire clinical operations managers in California?

Employers hiring clinical operations managers in California right now include Revolution Medicines, Cedars-Sinai Medical Center, and Exelixis, based on current listings on Migrate Mate as of October 2026. California's concentration of integrated health systems and biotech headquarters means demand is spread across both patient-care operations and sponsor-side clinical development.

Which California cities have the most clinical operations manager jobs?

Redwood City, San Diego, and Los Angeles have the most clinical operations manager openings in California. The Bay Area and San Diego lead because of their dense biotech and pharmaceutical headquarters, while Los Angeles draws volume from large academic medical centers and health system networks like Cedars-Sinai and UCLA Health that run complex multi-site clinical programs.

Are there remote clinical operations manager jobs in California?

Yes, and more than most healthcare roles. About 39% of clinical operations manager openings tied to California are remote or hybrid as of October 2026, reflecting the coordination-heavy nature of the work. The functions most commonly done remotely are trial oversight, vendor management, protocol development, and cross-site reporting, while roles with direct site monitoring or staff supervision responsibilities typically require on-site presence.

How can I get hired as a clinical operations manager in California with little or no experience?

The most realistic entry path is transitioning from a clinical coordinator, research associate, or project coordinator role at a California hospital system or biotech sponsor. Large California employers including Kaiser Permanente and UCSF Health run structured clinical operations rotational or associate programs that develop candidates without formal management backgrounds. Building ICH-GCP certification and experience with a clinical trial management system, even in a coordinator capacity, is the credential combination that most directly opens the door to a first operations manager title.

Where can I find and apply to clinical operations manager jobs in California?

You can find and apply to clinical operations manager jobs in California on Migrate Mate, which lists current California openings updated regularly. Search the listings for roles that match your background, experience level, and preferred location within the state, then apply directly to the ones that fit.

See All 77 Clinical Operations Manager Jobs in California

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