Clinical Operations Manager Jobs in North Carolina

Clinical Operations Manager jobs in North Carolina are in strong and consistent demand, concentrated in pharmaceutical and biotech research, academic medical centers, and multi-site health system operations, with openings at every level from coordinator-to-manager transitions through senior and executive clinical operations roles. The largest hiring metros are the Research Triangle (Raleigh, Durham, and Chapel Hill), Charlotte, and Greensboro, where employers such as Duke University Health System, Novant Health, and Labcorp maintain deep and ongoing hiring needs. The most in-demand specialties include clinical trial operations, ambulatory care coordination, and revenue cycle and quality improvement management. Find a role that fits below and apply directly.

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Overview

Open roles21
Top employerKBR
Top cityRaleigh, NC
Cities hiring10
Work type50% Remote
Top industryHealthcare

Showing 5 of 21+ Clinical Operations Manager jobs

IQVIA
Associate Director, Clinical Operations
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IQVIA
Added 2d ago
Associate Director, Clinical Operations
IQVIA
Durham, North Carolina
Business Operations
Customer Service
Project Management
$97k - $271k/yr
Remote (US)
Bachelor's degree
10,000+

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Sunny Skies ABA
Clinical Operations Supervisor/ BCBA
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Sunny Skies ABA
Added 2d ago
Clinical Operations Supervisor/ BCBA
Sunny Skies ABA
Raleigh, North Carolina
Business Analysis
Compliance & Legal
Compliance & Risk
Consulting & Professional Services
$95k - $140k/yr
Hybrid
Master's degree in applied behavior analysis
11-50

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Sitero LLC
Vice President, Clinical Operations
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Sitero LLC
Added 5d ago
Vice President, Clinical Operations
Sitero LLC
Raleigh, North Carolina
Business Operations
Program Management
Project Management
Remote (US)
Master's degree in business administration

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Eventus WholeHealth
Area Director Clinical Ops & Engagement
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Eventus WholeHealth
Added 5d ago
Area Director Clinical Ops & Engagement
Eventus WholeHealth
Durham, North Carolina
Corporate Training
Corporate Training & Learning Development
Teaching & Instruction
Doctoral degree
1,001-5,000

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Eventus WholeHealth
Area Director Clinical Ops & Engagement
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Eventus WholeHealth
Added 5d ago
Area Director Clinical Ops & Engagement
Eventus WholeHealth
Rocky Mount, North Carolina
Corporate Training
Corporate Training & Learning Development
Teaching & Instruction
Doctoral degree
1,001-5,000

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See All 21 Clinical Operations Manager Jobs in North Carolina

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Clinical Operations Manager Jobs by City in North Carolina

Where North Carolina roles are concentrated, by current openings.

Raleigh
6 jobs
Fayetteville
4 jobs
Durham
2 jobs
Charlotte
2 jobs
Faison
1 job
Gastonia
1 job
Fort Bragg
1 job
Chapel Hill
1 job
Rocky Mount
1 job

Clinical Operations Manager Job Market in North Carolina

A snapshot from current North Carolina openings, updated as new roles post.

Who's Hiring

KBR
KBR3 open roles
Eventus WholeHealth
Eventus WholeHealth3 open roles
CenterWell
CenterWell2 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What North Carolina Employers Look For

The qualifications that appear most often in clinical operations manager jobs across North Carolina.

  • Bachelor's degree in health administration, nursing, life sciences, or a related clinical field
  • Three or more years of progressive experience in clinical or healthcare operations
  • Demonstrated experience managing cross-functional teams in a regulated healthcare environment
  • Familiarity with Joint Commission standards, CMS conditions, and North Carolina DHHS compliance requirements
  • Proficiency with electronic health record systems such as Epic or Cerner in an operational capacity
  • PMP, CPHQ, or equivalent project or quality management certification preferred by many North Carolina employers

Clinical Operations Manager Jobs in North Carolina: Frequently Asked Questions

How do you become a clinical operations manager in North Carolina?

Most clinical operations manager roles in North Carolina require a bachelor's degree in health administration, nursing, public health, or a clinical science, with a master's degree preferred at larger health systems and academic medical centers. There is no single state-issued license for this management role, but candidates coming from a clinical background such as nursing must hold an active license recognized by the North Carolina Board of Nursing. Employers in the Research Triangle and Charlotte corridor consistently prioritize candidates with experience in regulated clinical environments and quality improvement frameworks.

Which companies hire clinical operations managers in North Carolina?

Employers hiring clinical operations managers in North Carolina right now include KBR, Eventus WholeHealth, and CenterWell, based on current listings on Migrate Mate as of August 2026. North Carolina's concentration of pharmaceutical companies, academic health systems, and multi-site ambulatory networks means hiring stays active across both the Research Triangle and the Charlotte market year-round.

Which North Carolina cities have the most clinical operations manager jobs?

The cities with the most clinical operations manager openings in North Carolina are Raleigh, Fayetteville, and Durham. The Research Triangle dominates because of its dense cluster of major health systems, contract research organizations, and pharmaceutical headquarters, while Charlotte's large hospital networks and growing outpatient market drive consistent hiring, and secondary hubs reflect regional health system expansion across the broader state.

Are there remote clinical operations manager jobs in North Carolina?

Yes, but they are selective. About 75% of clinical operations manager openings tied to North Carolina are remote or hybrid as of August 2026, reflecting the role's blend of on-site leadership responsibilities and administrative oversight work. The functions most likely to be performed remotely include data reporting, vendor management, protocol review, and cross-site program coordination, while direct staff supervision and facility operations typically require on-site presence.

How can I get hired as a clinical operations manager in North Carolina with little or no experience?

The most realistic entry path is moving into the role laterally from a clinical coordinator, patient services supervisor, or practice administrator position within a North Carolina health system or multi-site clinic group. Duke Health, Atrium Health, and UNC Health all run new-grad administrative fellowships and healthcare management development programs that place candidates without direct management experience into structured rotations. Earning a Certified Healthcare Administrative Professional credential or completing a graduate certificate in health administration through a North Carolina university also strengthens early-career applications significantly.

Where can I find and apply to clinical operations manager jobs in North Carolina?

You can find and apply to clinical operations manager jobs in North Carolina on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the available roles, find the ones that match your experience and location, and apply directly to the positions that fit.

See All 21 Clinical Operations Manager Jobs in North Carolina

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