Clinical Operations Manager Jobs in North Carolina
Clinical Operations Manager jobs in North Carolina are in strong and consistent demand, concentrated in pharmaceutical and biotech research, academic medical centers, and multi-site health system operations, with openings at every level from coordinator-to-manager transitions through senior and executive clinical operations roles. The largest hiring metros are the Research Triangle (Raleigh, Durham, and Chapel Hill), Charlotte, and Greensboro, where employers such as Duke University Health System, Novant Health, and Labcorp maintain deep and ongoing hiring needs. The most in-demand specialties include clinical trial operations, ambulatory care coordination, and revenue cycle and quality improvement management. Find a role that fits below and apply directly.
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Durham, United States of America | Full time | Home-based | R1565168
IQVIA is seeking an Associate Director, Clinical Operations:
Job Overview
Direct a team of clinical staff working in support of clinical studies to ensure projects are appropriately resourced and employees are trained and meeting project objectives. Work with senior leadership in formulating effective strategic goals and objectives for designated organization and assures operational alignment with organization priorities.
Essential Functions
• Manage staff in accordance with organization’s policies and applicable regulations. Responsibilities include planning, assigning, and directing work
• appraising performance and guiding professional development
• rewarding and disciplining employees
• addressing employee relations issues and resolving problems.
• Direct the hiring and selection process for clinical staff by participating in the interviewing process. Ensure that new employees are properly onboarded and trained.
• Ensure that staff has the proper materials, systems access and training to complete job responsibilities. Provide oversight for the execution of the training plan, SOP review and training experiences, as applicable.
• Allocate resources to clinical research projects by assigning staff to clinical studies that are appropriate based on their experience and training.
• May participate in coordinated resourcing process. Manage the quality of assigned staff's clinical work through regular review and evaluation of work product. This review may include review of written materials, soliciting internal and external customer feedback, and review of project assignment completion.
• Identifies quality risks and issues and create appropriate corrective action plans.
• Ensure that staff is meeting defined workload, quality and budget metrics through regular review and reporting of findings as outlined by senior management.
• May collaborate with other regional and/or global clinical and client teams and other functional leadership to manage project related challenges and to achieve exemplary customer service.
• Participates in corporate or organizational quality or process improvement initiatives.
• May act as a client liaison in day-to-day relationship governance, escalations and other client-facing initiatives.
• May manage other managers.
Qualifications
• Bachelor's Degree Degree in scientific discipline or health care preferred.
• At least 7 years prior clinical trial experience including experience in a management/leadership capacity or equivalent combination of education, training and experience.
• Advanced knowledge of applicable clinical research regulatory requirements (i.e., Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) guidelines).
• Knowledge of clinical research financial parameters and project financial tracking and accounting methods.
• Strong leadership skills.
• Effective presentation skills.
• Computer skills including proficiency in use of Microsoft Word, Excel and PowerPoint.
• Written and verbal communication skills including good command of English.
• Excellent organizational and problem solving skills.
• Effective time management skills and ability to manage competing priorities.
• Ability to establish and maintain effective working relationships with coworkers, managers, and clients.
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com
IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe
IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
The potential base pay range for this role, when annualized, is $97,200.00 - $270,700.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.Where you'll work
Home-based
You’ll work remotely, with the flexibility to do your best work from home. Supported by collaborative tools and a global team, you’ll stay connected while enjoying the autonomy and balance that comes with a fully remote role.
Culture
Culture at IQVIA is built on a shared belief: that when people are empowered with better data, smarter technology and deeper expertise, they can change what’s possible for patients. Across every team and every corner of the globe, you’ll find colleagues who genuinely care — about the mission and about each other. That’s what makes this a place where people tend to stay, grow and do the best work of their careers.
See All 21 Clinical Operations Manager Jobs in North Carolina
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Find JobsClinical Operations Manager Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Clinical Operations Manager Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What North Carolina Employers Look For
The qualifications that appear most often in clinical operations manager jobs across North Carolina.
- Bachelor's degree in health administration, nursing, life sciences, or a related clinical field
- Three or more years of progressive experience in clinical or healthcare operations
- Demonstrated experience managing cross-functional teams in a regulated healthcare environment
- Familiarity with Joint Commission standards, CMS conditions, and North Carolina DHHS compliance requirements
- Proficiency with electronic health record systems such as Epic or Cerner in an operational capacity
- PMP, CPHQ, or equivalent project or quality management certification preferred by many North Carolina employers
Clinical Operations Manager Jobs in North Carolina: Frequently Asked Questions
How do you become a clinical operations manager in North Carolina?
Most clinical operations manager roles in North Carolina require a bachelor's degree in health administration, nursing, public health, or a clinical science, with a master's degree preferred at larger health systems and academic medical centers. There is no single state-issued license for this management role, but candidates coming from a clinical background such as nursing must hold an active license recognized by the North Carolina Board of Nursing. Employers in the Research Triangle and Charlotte corridor consistently prioritize candidates with experience in regulated clinical environments and quality improvement frameworks.
Which companies hire clinical operations managers in North Carolina?
Employers hiring clinical operations managers in North Carolina right now include KBR, Eventus WholeHealth, and CenterWell, based on current listings on Migrate Mate as of August 2026. North Carolina's concentration of pharmaceutical companies, academic health systems, and multi-site ambulatory networks means hiring stays active across both the Research Triangle and the Charlotte market year-round.
Which North Carolina cities have the most clinical operations manager jobs?
The cities with the most clinical operations manager openings in North Carolina are Raleigh, Fayetteville, and Durham. The Research Triangle dominates because of its dense cluster of major health systems, contract research organizations, and pharmaceutical headquarters, while Charlotte's large hospital networks and growing outpatient market drive consistent hiring, and secondary hubs reflect regional health system expansion across the broader state.
Are there remote clinical operations manager jobs in North Carolina?
Yes, but they are selective. About 75% of clinical operations manager openings tied to North Carolina are remote or hybrid as of August 2026, reflecting the role's blend of on-site leadership responsibilities and administrative oversight work. The functions most likely to be performed remotely include data reporting, vendor management, protocol review, and cross-site program coordination, while direct staff supervision and facility operations typically require on-site presence.
How can I get hired as a clinical operations manager in North Carolina with little or no experience?
The most realistic entry path is moving into the role laterally from a clinical coordinator, patient services supervisor, or practice administrator position within a North Carolina health system or multi-site clinic group. Duke Health, Atrium Health, and UNC Health all run new-grad administrative fellowships and healthcare management development programs that place candidates without direct management experience into structured rotations. Earning a Certified Healthcare Administrative Professional credential or completing a graduate certificate in health administration through a North Carolina university also strengthens early-career applications significantly.
Where can I find and apply to clinical operations manager jobs in North Carolina?
You can find and apply to clinical operations manager jobs in North Carolina on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the available roles, find the ones that match your experience and location, and apply directly to the positions that fit.
See All 21 Clinical Operations Manager Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
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