Clinical Operations Manager Jobs in Illinois

Clinical Operations Manager jobs in Illinois are in strong demand, concentrated in hospital systems, pharmaceutical and biotech companies, academic medical centers, and clinical research organizations across the state, with openings at every level from coordinator to senior director. Chicago, Peoria, and Rockford are the primary hiring hubs, anchored by major employers such as Northwestern Medicine, Abbott Laboratories, and OSF HealthCare. The most sought-after specialties include clinical trials management, oncology program operations, and value-based care coordination. Find a role that fits below and apply directly.

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Overview

Open roles21
Top employerNorthwestern Medicine
Top cityChicago, IL
Cities hiring10
Work type57% On-site
Top industryEducation

Showing 5 of 21+ Clinical Operations Manager jobs

W
Director of Clinical Operations
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W
Added 2d ago
Director of Clinical Operations
WovenX Health, Inc.
Chicago, Illinois
Customer Service
Customer Success
Customer Support
$165k - $200k/yr
Hybrid
Master's degree in business administration

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U
Clinical Operations and EMR technology Coordinator
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U
Added 3d ago
Clinical Operations and EMR technology Coordinator
university pain centers
Westchester, Illinois
Biotech & Life Sciences
Clinical Trials
Healthcare Administration
Research & Academia
$19.5 - $22/hr
On-Site
High school diploma or GED

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Northwestern Medicine
Clinical Operations Coordinator RN - Family Medicine Bloomingdale and Bartlett
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Northwestern Medicine
Added 5d ago
Clinical Operations Coordinator RN - Family Medicine Bloomingdale and Bartlett
Northwestern Medicine
Bloomingdale, Illinois
Communications
Content & Communications
Public Relations (PR)
$38.5 - $61.6/hr
BLS Certification
10,000+

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Midwest Cardiovascular Institute
Director of Clinical Operations
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Midwest Cardiovascular Institute
Added 6d ago
Director of Clinical Operations
Midwest Cardiovascular Institute
Naperville, Illinois
Business Development
Growth Marketing
Marketing
Managed Registered Nurses (RNs)
51-200

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AbbVie
Clinical Data Strategy and Operations Program Lead I - Oncology- HYBRID
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AbbVie
Added 6d ago
Clinical Data Strategy and Operations Program Lead I - Oncology- HYBRID
AbbVie
North Chicago, Illinois
Business Operations
Business Strategy
Project Management
$79k - $141k/yr
Hybrid
Bachelor's degree in management information systems
10,000+

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See All 21 Clinical Operations Manager Jobs in Illinois

Find roles in Illinois that match your experience and apply in just a few clicks.

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Clinical Operations Manager Jobs by City in Illinois

Where Illinois roles are concentrated, by current openings.

Chicago
11 jobs
Bloomingdale
2 jobs
Peoria
1 job
Winfield
1 job
Champaign
1 job
Naperville
1 job
Des Plaines
1 job
Springfield
1 job
Westchester
1 job

Clinical Operations Manager Job Market in Illinois

A snapshot from current Illinois openings, updated as new roles post.

Who's Hiring

Northwestern Medicine
Northwestern Medicine4 open roles
Dozee
Dozee1 open role
AbbVie
AbbVie1 open role

Top Industries Hiring

  • Education
  • Healthcare & Medical Services

What Illinois Employers Look For

The qualifications that appear most often in clinical operations manager jobs across Illinois.

  • Bachelor's degree in healthcare administration, nursing, or a life sciences field
  • Active Illinois clinical license or recognized clinical credential preferred by most health systems
  • Minimum five years of experience in healthcare operations or clinical program management
  • Demonstrated experience managing clinical staff, budgets, and regulatory compliance in Illinois settings
  • Proficiency with electronic health record systems such as Epic or Cerner
  • Strong knowledge of Joint Commission standards and Illinois Department of Public Health regulations

Clinical Operations Manager Jobs in Illinois: Frequently Asked Questions

How do you become a clinical operations manager in Illinois?

Most clinical operations managers in Illinois start with a bachelor's degree in nursing, healthcare administration, or a related clinical field, then build several years of frontline clinical or program experience before moving into management. Illinois does not issue a dedicated state license for the manager title itself, but many employers require an active clinical license such as a Registered Nurse license issued through the Illinois Department of Financial and Professional Regulation. An advanced degree or a Certified Healthcare Manager credential strengthens candidacy significantly.

Which companies hire clinical operations managers in Illinois?

Employers hiring clinical operations managers in Illinois right now include Northwestern Medicine, Dozee, and AbbVie, based on current listings on Migrate Mate as of August 2026. Illinois's concentration of large integrated health systems, contract research organizations, and life sciences headquarters in the Chicago metro makes it one of the more active states for this role year-round.

Which Illinois cities have the most clinical operations manager jobs?

Chicago, Bloomingdale, and Peoria have the most clinical operations manager openings in Illinois. Chicago dominates the distribution because it hosts the corporate headquarters of major health systems, pharmaceutical companies, and research institutions, while Peoria and Rockford anchor significant regional health systems such as OSF HealthCare and Mercyhealth that generate consistent management openings outside the metro area.

Are there remote clinical operations manager jobs in Illinois?

Yes, but they are less common than in purely desk-based fields because the role typically involves direct oversight of clinical staff, facilities, and on-site operations. About 43% of clinical operations manager openings tied to Illinois are remote or hybrid as of August 2026, with those positions most often covering functions like clinical trial monitoring, policy development, or multi-site program coordination that can be handled off-site.

How can I get hired as a clinical operations manager in Illinois with little or no experience?

The most realistic entry path is moving laterally from a clinical role such as registered nurse, medical assistant lead, or clinical research coordinator into a team lead or assistant manager position within the same organization. Large Illinois health systems including Northwestern Medicine and Advocate Health run structured leadership development programs aimed at frontline clinical staff. Earning a Certified Medical Manager credential or completing a healthcare administration graduate certificate through an Illinois university strengthens applications before direct management experience is on the resume.

Where can I find and apply to clinical operations manager jobs in Illinois?

You can find and apply to clinical operations manager jobs in Illinois on Migrate Mate, which lists current Illinois openings updated on an ongoing basis. Find roles that fit your experience and location and apply directly to the employers posting them.

See All 21 Clinical Operations Manager Jobs in Illinois

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