Clinical Operations Manager Jobs in Illinois
Clinical Operations Manager jobs in Illinois are in strong demand, concentrated in hospital systems, pharmaceutical and biotech companies, academic medical centers, and clinical research organizations across the state, with openings at every level from coordinator to senior director. Chicago, Peoria, and Rockford are the primary hiring hubs, anchored by major employers such as Northwestern Medicine, Abbott Laboratories, and OSF HealthCare. The most sought-after specialties include clinical trials management, oncology program operations, and value-based care coordination. Find a role that fits below and apply directly.
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Showing 5 of 27+ Clinical Operations Manager jobs
The Supervisor, Clinical Operations provides support to organizational initiatives, serves in leadership roles on committees, and partners with organizational departments to create an optimal patient experience. The Supervisor serves as a clinical content expert who is able to accurately and effectively disseminate knowledge and mentor peers. The Supervisor supports and provides input for the local and external nursing profession in collaboration with the group's clinical leadership team.
In addition, the Supervisor is responsible for the assessment, planning, implementation, and evaluation of the patients’ status, plan of care, and goal achievement. Care is provided in a compassionate, professional, ethical, and knowledgeable fashion based on the Caring Model, exemplifies the mission, vision and values of Rush Copley, and is in accordance with policies and procedures. The Supervisor is expected to uphold the most ethical and safe processes while keeping the care of the patient as a top priority. The position works closely with the entire multidisciplinary team and must have a complete understanding of own limitations and, in turn, seek advice, judgment and support of others, when necessary.
Requirements: Associate’s Degree in Nursing required, Bachelor’s degree in Nursing preferred. For hires or transfers on/after 8/1/2013, must attain a BSN within 5 years of hire/transfer date.
- Excellent oral/written communication skills
- Excellent organizational skills
- Detail-oriented
- Ability to set priorities, document conversations and specific actions taken and develop applicable policies and procedures
- Flexible; able to adapt to change
Experience:
- Medical practice management and EMR software experience
- Prefer one year of ambulatory nursing experience
Rush salaries are determined by many factors including, but not limited to, education, job-related experience and skills, as well as internal equity and industry specific market data. The pay range for each role reflects RUSH’s anticipated wage or salary reasonably expected to be offered for the position. Offers may vary depending on the circumstances of each case. Benefits can be found here
Location: Rush Copley Medical Center · RMG Primary Care Aurora
Schedule: Full-time, First shift, 7:30am-4pm
The Supervisor, Clinical Operations provides support to organizational initiatives, serves in leadership roles on committees, and partners with organizational departments to create an optimal patient experience. The Supervisor serves as a clinical content expert who is able to accurately and effectively disseminate knowledge and mentor peers. The Supervisor supports and provides input for the local and external nursing profession in collaboration with the group's clinical leadership team.
In addition, the Supervisor is responsible for the assessment, planning, implementation, and evaluation of the patients’ status, plan of care, and goal achievement. Care is provided in a compassionate, professional, ethical, and knowledgeable fashion based on the Caring Model, exemplifies the mission, vision and values of Rush Copley, and is in accordance with policies and procedures. The Supervisor is expected to uphold the most ethical and safe processes while keeping the care of the patient as a top priority. The position works closely with the entire multidisciplinary team and must have a complete understanding of own limitations and, in turn, seek advice, judgment and support of others, when necessary.
Requirements: Associate’s Degree in Nursing required, Bachelor’s degree in Nursing preferred. For hires or transfers on/after 8/1/2013, must attain a BSN within 5 years of hire/transfer date.
- Excellent oral/written communication skills
- Excellent organizational skills
- Detail-oriented
- Ability to set priorities, document conversations and specific actions taken and develop applicable policies and procedures
- Flexible; able to adapt to change
Experience:
- Medical practice management and EMR software experience
- Prefer one year of ambulatory nursing experience
Rush salaries are determined by many factors including, but not limited to, education, job-related experience and skills, as well as internal equity and industry specific market data. The pay range for each role reflects RUSH’s anticipated wage or salary reasonably expected to be offered for the position. Offers may vary depending on the circumstances of each case. Benefits can be found here
Location: Rush Copley Medical Center · RMG Primary Care Aurora
Schedule: Full-time, First shift, 7:30am-4pm
See All 27 Clinical Operations Manager Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find JobsClinical Operations Manager Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Clinical Operations Manager Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Education
- Healthcare & Medical Services
What Illinois Employers Look For
The qualifications that appear most often in clinical operations manager jobs across Illinois.
- Bachelor's degree in healthcare administration, nursing, or a life sciences field
- Active Illinois clinical license or recognized clinical credential preferred by most health systems
- Minimum five years of experience in healthcare operations or clinical program management
- Demonstrated experience managing clinical staff, budgets, and regulatory compliance in Illinois settings
- Proficiency with electronic health record systems such as Epic or Cerner
- Strong knowledge of Joint Commission standards and Illinois Department of Public Health regulations
Clinical Operations Manager Jobs in Illinois: Frequently Asked Questions
How do you become a clinical operations manager in Illinois?
Most clinical operations managers in Illinois start with a bachelor's degree in nursing, healthcare administration, or a related clinical field, then build several years of frontline clinical or program experience before moving into management. Illinois does not issue a dedicated state license for the manager title itself, but many employers require an active clinical license such as a Registered Nurse license issued through the Illinois Department of Financial and Professional Regulation. An advanced degree or a Certified Healthcare Manager credential strengthens candidacy significantly.
Which companies hire clinical operations managers in Illinois?
Employers hiring clinical operations managers in Illinois right now include Northwestern Medicine, Tempus, and UChicago Medicine, based on current listings on Migrate Mate as of October 2026. Illinois's concentration of large integrated health systems, contract research organizations, and life sciences headquarters in the Chicago metro makes it one of the more active states for this role year-round.
Which Illinois cities have the most clinical operations manager jobs?
Chicago, Illinois, and Aurora have the most clinical operations manager openings in Illinois. Chicago dominates the distribution because it hosts the corporate headquarters of major health systems, pharmaceutical companies, and research institutions, while Peoria and Rockford anchor significant regional health systems such as OSF HealthCare and Mercyhealth that generate consistent management openings outside the metro area.
Are there remote clinical operations manager jobs in Illinois?
Yes, but they are less common than in purely desk-based fields because the role typically involves direct oversight of clinical staff, facilities, and on-site operations. About 63% of clinical operations manager openings tied to Illinois are remote or hybrid as of October 2026, with those positions most often covering functions like clinical trial monitoring, policy development, or multi-site program coordination that can be handled off-site.
How can I get hired as a clinical operations manager in Illinois with little or no experience?
The most realistic entry path is moving laterally from a clinical role such as registered nurse, medical assistant lead, or clinical research coordinator into a team lead or assistant manager position within the same organization. Large Illinois health systems including Northwestern Medicine and Advocate Health run structured leadership development programs aimed at frontline clinical staff. Earning a Certified Medical Manager credential or completing a healthcare administration graduate certificate through an Illinois university strengthens applications before direct management experience is on the resume.
Where can I find and apply to clinical operations manager jobs in Illinois?
You can find and apply to clinical operations manager jobs in Illinois on Migrate Mate, which lists current Illinois openings updated on an ongoing basis. Find roles that fit your experience and location and apply directly to the employers posting them.
See All 27 Clinical Operations Manager Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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