Clinical Operations Manager Jobs in Massachusetts
Clinical Operations Manager jobs in Massachusetts are among the most active in the country, concentrated in clinical research, hospital systems, and biotech and pharma operations, with openings from coordinator-level roles stepping into management through senior director positions. Boston, Cambridge, and Worcester drive the bulk of hiring, anchored by institutions and employers such as Mass General Brigham, Dana-Farber Cancer Institute, and Biogen, all of which maintain large and ongoing clinical operations functions. Regulatory affairs oversight, site management, and oncology trial operations are the most consistently in-demand specialties across Massachusetts listings. Find a role that fits below and apply directly.
Find JobsOverview
Showing 4 of 40+ Clinical Operations Manager jobs
Are you passionate about driving operational efficiency in clinical production? Join us as a dynamic Senior Process Engineer to revolutionize our clinical production processes and build out workflows for our team of medical imaging analysts. In this pivotal role, you'll develop key operational metrics, design seamless workflows, and foster team and cross-functional collaboration. You'll work hand-in-hand with our talented 3D CT analysts, as well as our Clinical QA, Software QA, and Product Management teams to propel our clinical operations to new heights as we rapidly scale and commercialize. Be part of our mission to advance cardiac care, at the forefront of transforming clinical operations in a fast-paced, cutting-edge environment.
The ideal candidate will have:
- Bachelor's degree in Engineering, Biomedical Engineering, or a related field.
- 5+ years of experience in process engineering or an operational optimization role with software-as-a-medical-device (SaMD) or medical imaging products.
- Lean and/or Six Sigma experience.
- Strong eye for optimization and a mindset of continuous improvement.
- Excellent problem-solving and analytical skills.
- Strong communication and collaboration abilities.
- Detail-oriented, with a focus on quality and compliance.
- This role is on-site, based out of our office in Boston, MA. We operate in a hybrid model with regular in-office collaboration.
- The anticipated base salary range for this position at Elucid is $135,00-$165,000. Compensation will be influenced by a wide array of factors including but not limited to internal pay equity, job-related knowledge, skills, education, relevant experience, certifications, and geography as outlined in the job description.
-
At Elucid, we believe the best work happens in a flexible hybrid environment. Boston-area employees are encouraged to work from the office on Mondays and Wednesdays, with the option to come in additional days if they prefer. Fully remote employees outside the Boston area come in as needed.
We are an equal opportunity employer and value diversity at Elucid. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability.
We understand that self-doubt can sometimes prevent great candidates from applying. If you believe you can make an impact at Elucid, even if you don’t meet every qualification, we encourage you to apply!
9PlF2dnUMo
Are you passionate about driving operational efficiency in clinical production? Join us as a dynamic Senior Process Engineer to revolutionize our clinical production processes and build out workflows for our team of medical imaging analysts. In this pivotal role, you'll develop key operational metrics, design seamless workflows, and foster team and cross-functional collaboration. You'll work hand-in-hand with our talented 3D CT analysts, as well as our Clinical QA, Software QA, and Product Management teams to propel our clinical operations to new heights as we rapidly scale and commercialize. Be part of our mission to advance cardiac care, at the forefront of transforming clinical operations in a fast-paced, cutting-edge environment.
The ideal candidate will have:
- Bachelor's degree in Engineering, Biomedical Engineering, or a related field.
- 5+ years of experience in process engineering or an operational optimization role with software-as-a-medical-device (SaMD) or medical imaging products.
- Lean and/or Six Sigma experience.
- Strong eye for optimization and a mindset of continuous improvement.
- Excellent problem-solving and analytical skills.
- Strong communication and collaboration abilities.
- Detail-oriented, with a focus on quality and compliance.
- This role is on-site, based out of our office in Boston, MA. We operate in a hybrid model with regular in-office collaboration.
- The anticipated base salary range for this position at Elucid is $135,00-$165,000. Compensation will be influenced by a wide array of factors including but not limited to internal pay equity, job-related knowledge, skills, education, relevant experience, certifications, and geography as outlined in the job description.
-
At Elucid, we believe the best work happens in a flexible hybrid environment. Boston-area employees are encouraged to work from the office on Mondays and Wednesdays, with the option to come in additional days if they prefer. Fully remote employees outside the Boston area come in as needed.
We are an equal opportunity employer and value diversity at Elucid. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability.
We understand that self-doubt can sometimes prevent great candidates from applying. If you believe you can make an impact at Elucid, even if you don’t meet every qualification, we encourage you to apply!
9PlF2dnUMo
See All 40 Clinical Operations Manager Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find JobsClinical Operations Manager Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Clinical Operations Manager Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Science & Research
- Healthcare & Medical Services
- Medical Devices
- Biotechnology & Pharmaceuticals
What Massachusetts Employers Look For
The qualifications that appear most often in clinical operations manager jobs across Massachusetts.
- Bachelor's degree in life sciences, nursing, or a health-related field required
- Minimum five years of clinical research or healthcare operations experience preferred
- ICH-GCP certification or equivalent clinical research credential expected
- Demonstrated experience managing clinical trial sites or multi-site operations
- Familiarity with FDA regulatory requirements and clinical study protocols
- Strong proficiency in electronic data capture systems such as Medidata or Veeva
Clinical Operations Manager Jobs in Massachusetts: Frequently Asked Questions
How do you become a clinical operations manager in Massachusetts?
Most clinical operations managers in Massachusetts enter the role through clinical research coordination or trial monitoring, typically after earning a bachelor's degree in a life science or health field. Massachusetts does not require a state-issued license specific to this management role, but employers strongly favor candidates who hold credentials such as the Certified Clinical Research Professional designation issued by the Society of Clinical Research Associates, or equivalent certification. Progression from CRC or CRA roles at Massachusetts research hospitals or biotech firms is the most common pathway.
Which companies hire clinical operations managers in Massachusetts?
Employers hiring clinical operations managers in Massachusetts right now include Takeda Pharmaceuticals, Adams Clinical, and Relay Therapeutics, based on current listings on Migrate Mate as of August 2026. Massachusetts's concentration of academic medical centers and global biotech headquarters means many of these employers are running multiple concurrent studies, creating consistent and varied openings across therapeutic areas.
Which Massachusetts cities have the most clinical operations manager jobs?
Boston, Cambridge, and Watertown have the most clinical operations manager openings in Massachusetts. Boston and Cambridge dominate because of their dense cluster of teaching hospitals, biotech headquarters, and contract research organizations, while Worcester's UMass Memorial Health system and growing life sciences corridor account for a meaningful share of listings outside the Route 128 belt.
Are there remote clinical operations manager jobs in Massachusetts?
Yes, and more than many clinical roles, because operations management in research settings involves considerable protocol oversight, vendor coordination, and reporting that can be done off-site. About 47% of clinical operations manager openings tied to Massachusetts are remote or hybrid as of August 2026, reflecting the desk-and-coordination nature of much of the work. Site-facing responsibilities tied to active clinical trial locations are the portions most likely to require on-site presence.
How can I get hired as a clinical operations manager in Massachusetts with little or no experience?
The most realistic entry path is through a clinical research coordinator role at a Massachusetts academic medical center or large community hospital, where you can build direct trial experience before moving into operations management. Mass General Brigham, Boston Children's Hospital, and Dana-Farber all run structured CRC programs that serve as feeders into operations leadership. Earning an entry-level credential such as the ACRP Associate Clinical Research Professional designation strengthens applications, and lateral moves from regulatory affairs or quality assurance roles are also recognized by Massachusetts biotech and pharma employers as relevant operations experience.
Where can I find and apply to clinical operations manager jobs in Massachusetts?
You can find and apply to clinical operations manager jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across clinical research, hospital systems, and biotech and pharma employers. Find the roles that fit your background and apply directly.
See All 40 Clinical Operations Manager Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Jobs