Senior ML Engineer Jobs in Florida
Senior ML Engineer jobs in Florida are in strong demand, concentrated in fintech, defense and aerospace, healthcare technology, and enterprise software, with openings at every level from early-career machine learning engineers through principal and staff roles. Miami, Tampa, and Orlando anchor the market, where established employers such as Lockheed Martin, Chewy, and Citi have built engineering teams with sustained ML headcount. Florida's growth in AI-driven financial services and defense contracting makes inference optimization, NLP, and MLOps the most sought-after specialties. Find a role that fits below and apply directly.
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Working at Moffitt is both a career and a mission: to contribute to the prevention and cure of cancer.
As the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, Moffitt employs some of the best and brightest minds from around the world. Join a dedicated team of nearly 11,000 who are shaping the future we envision. Moffitt has been recognized as a Best and Brightest Company to Work For in the Nation and is continually named one of the Tampa Bay Times’ Top Workplaces.
Summary
Dr. Ghulam Rasool seeks an Applied Postdoctoral Research Fellow to join his lab and develop and apply advanced AI methods for multimodal cancer patient modeling. The research will focus on federated learning across distributed clinical data environments, with applications in matching patients to clinical trials, predicting treatment response and outcomes, stratifying risk, and personalizing cancer care.
Position Highlights:
- The position offers a unique opportunity to work in a world-class research environment, with state-of-the-art facilities and strong collaboration with many researchers and clinicians from diverse fields.
- It offers exciting opportunities for developing new machine learning models for integrating multiscale heterogeneous cancer datasets.
- Opportunity for applying new machine learning approaches in pre-clinical and clinical model development.
- Moffitt integrates excellent patient care with cutting-edge clinical and basic research. Having a cancer hospital on-site provides unique opportunities for translational research.
- Outstanding mentorship from expert faculty with wide-ranging funded research programs, including T32 Training Grants.
- You will be encouraged and supported to apply for training grants.
The Ideal Candidate:
- Expertise in natural language processing (NLP), large language models (LLMs), medical imaging, and multimodal machine learning, with experience integrating structured and unstructured clinical data, including electronic health record (EHR) and clinical text, medical imaging, pathology, and molecular data.
- Experience with federated learning, privacy-preserving AI, clinical prediction, patient-trial matching, and modern deep learning frameworks is highly desirable.
Responsibilities:
- Develop new machine learning models using Transformers and/or GNNs for multimodal cancer data integration, including radiology, pathology, and clinical data.
- Develop pipelines for image, text, and tabular data processing for the machine learning models.
- Develop privacy-preserving and federated learning approaches across distributed clinical data environments to support patient-trial matching, treatment response and outcome prediction, risk stratification, and personalized cancer care.
- Collaborate with team members on developing and implementing these technologies in preclinical and clinical settings, manuscript writing, and generating data for grant applications.
Credentials and Qualifications:
- A PhD or equivalent degree in Electrical, Biomedical and/or Computer Engineering/Computer Sciences/Mathematics/Physics or related discipline is required.
- Should have at least one first-author publication.
Moffitt Postdocs enjoy comprehensive medical coverage, with Moffitt covering the premium effective your very first day. In addition to this valuable benefit, you’ll also be eligible for dental and vision insurance, generous paid time off, retirement, parental leave, and much more. Furthermore, you may qualify for relocation assistance as per our policy, ensuring a seamless transition to your exciting new role.
Moffitt Cancer Center proudly stands as a Comprehensive Cancer Center designated by the National Cancer Institute (NCI) in the vibrant city of Tampa, Florida. This dynamic city is an exceptional choice for those seeking exciting opportunities in a rapidly growing metropolitan area. With its flourishing economy and rich cultural diversity, the Tampa Bay region masterfully combines urban elegance with breathtaking natural beauty. Discover why countless individuals have chosen to make Tampa their home and experience firsthand what makes it one of the fastest-growing metropolitan cities in the United States.
How to Apply: Interested applicants should send a single PDF file that includes a cover letter summarizing their research training and accomplishments, a personal statement of research interests and goals, current CV with recent publications, and contact information for three references to Dr. Rasool (ghulam.rasool@moffitt.org).
Salary Range
Salary ranges posted for this position represent the expected base pay range for the role. Actual compensation may vary based on location and a variety of job-related factors, including experience, skills, education, and internal equity among Team Members in similar positions.
We are committed to maintaining fair and equitable pay practices and regularly review compensation to ensure alignment across our workforce.
Moffitt Career Site
If you have the vision, passion, and dedication to contribute to our mission,
then we have a place for you!
1. Equal Employment Opportunity
Moffitt Cancer Center is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, or protected veteran or disabled status. We seek candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence.
2. Reasonable Accommodation
Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. Moffitt endeavors to make moffitt.org/careers accessible to any and all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process, please contact one of the Human Resources receptionists by phone at 813-745-7899 or by email at HRReceptionists@moffitt.org. This contact information is for accommodation requests only and cannot be used to inquire about the status of applications.
Read more information about your EEO rights under the law.
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See All 17 Senior ML Engineer Jobs in Florida
Find roles in Florida that match your experience and apply in just a few clicks.
Find Senior ML Engineer JobsSenior ML Engineer Jobs by City in Florida
Where Florida roles are concentrated, by current openings.
Senior ML Engineer Job Market in Florida
A snapshot from current Florida openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Education
- Banking & Financial Services
- Consulting & Professional Services
What Florida Employers Look For
The qualifications that appear most often in senior ML engineer jobs across Florida.
- Bachelor's or master's degree in computer science, statistics, or a related quantitative field
- Five or more years of hands-on experience building and deploying production ML systems
- Proficiency in Python and core ML frameworks such as TensorFlow, PyTorch, or scikit-learn
- Experience designing MLOps pipelines, model monitoring, and CI/CD workflows for ML
- Strong background in one or more Florida-relevant domains: fintech, defense, or healthcare AI
- Ability to lead technical design reviews and mentor junior engineers on ML best practices
Senior ML Engineer Jobs in Florida: Frequently Asked Questions
How do you become a senior ml engineer in Florida?
Senior ML engineer roles in Florida do not require a state-issued license, so the path runs through education and demonstrated experience. Most hiring managers expect at least a bachelor's degree in computer science, mathematics, or a related field, with a master's preferred at larger defense and fintech employers. Building a portfolio of production ML systems, contributing to open-source projects, and earning cloud ML certifications strengthens candidacy considerably in Florida's competitive market.
How much do senior ML engineers make in Florida?
Senior ML engineers in Florida earn a median of about $105,370 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $52,960 for the lowest 10% to over $173,260 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior ml engineers in Florida?
Employers hiring senior ml engineers in Florida right now include Moffitt Cancer Center, University of South Florida, and FIS, based on current listings on Migrate Mate as of November 2026. Florida's defense corridor near Orlando and the fintech and banking sector concentrated in Miami and Tampa produce some of the most consistent senior-level openings in the state.
Which Florida cities have the most senior ml engineer jobs?
Tampa, Miami, and Florida have the most senior ml engineer openings in Florida. Miami leads because of its dense fintech, banking, and tech-startup ecosystem, Tampa draws demand from healthcare IT and insurance analytics firms headquartered there, and Orlando's concentration of defense contractors and simulation technology companies sustains steady ML engineering hiring even outside the largest coastal metros.
Are there remote senior ml engineer jobs in Florida?
Yes, and more than most fields. ML engineering is a desk-based, highly technical discipline that transfers well to remote work, making it one of the more remote-accessible roles in tech. About 60% of senior ml engineer openings tied to Florida are remote or hybrid as of November 2026, reflecting how broadly Florida employers have adopted flexible arrangements for this role. Research and modeling work is most often fully remote, while roles involving proprietary data or defense clearances tend to require on-site presence.
How can I get hired as a senior ml engineer in Florida with little or no experience?
The most realistic entry path is through a junior or associate machine learning engineer role, targeting Florida employers with structured new-grad programs. Large defense and aerospace firms near Orlando, including Lockheed Martin and L3Harris, run engineering rotational programs that place candidates without prior industry experience into ML-adjacent teams. Healthcare technology companies in Tampa have similar associate data science tracks. Building a GitHub portfolio of end-to-end ML projects and earning a cloud provider ML certification gives candidates without work history a credible edge.
Where can I find and apply to senior ml engineer jobs in Florida?
You can find and apply to senior ml engineer jobs in Florida on Migrate Mate, which lists current Florida openings from employers hiring now. Search the listings, find roles that match your experience and the Florida market you want to work in, and apply directly to each one.
See All 17 Senior ML Engineer Jobs in Florida
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