Senior Web Engineer Jobs in North Carolina
Senior Web Engineer jobs in North Carolina are open across Charlotte, Raleigh, and Durham and other North Carolina metros, with employers like ALG Senior, Thermo Fisher Scientific, and NVIDIA hiring at every experience level. Find a role that fits below and apply directly.
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About This Role
We are seeking an experienced technical contributor to join our Automation Systems Engineering team at the Biogen RTP Bio site. The Senior Automation Engineer I will support Syncade (MES) system administration within a GMP-regulated manufacturing environment. This role operates with a high degree of independence and is accountable for ensuring system reliability, supporting manufacturing execution, and driving continuous improvement initiatives. The Senior Automation Engineer I will be a subject matter expert for Syncade, capable of leading small-to-moderate complexity initiatives to influence cross-functional outcomes.
What You’ll Do
- Act as system administrator/SME for Syncade (MES), including configuration, maintenance, troubleshooting, and lifecycle management
- Own and support Syncade Application and the relevant infrastructure to enable electronic batch record (eBR) workflows, recipe configuration, and exception handling
- Ensure system availability, performance, and data integrity to support GMP manufacturing operations
- Lead root cause investigations and implement corrective/preventive actions for MES-related deviations
- Manage user access, security roles, and audit trail reviews in compliance with GxP and cybersecurity requirements
- Execute and support change controls, including system updates, enhancements, and validation deliverables (IQ/OQ/PQ)
- Drive continuous improvement efforts to enhance system usability, reliability, and operational efficiency
- Support integration and data flow between Syncade and other automation and Enterprise systems, e.g. DeltaV, PI, and Infobatch, CMMS, Oracle, Veeva, LIMS
- Provide technical support during manufacturing operations, including off-hours support as required
Who You Are
You are a meticulous professional with a strong foundation in automation/manufacturing systems engineering, particularly in biopharmaceutical settings. Your analytical mindset and problem-solving skills empower you to tackle complex challenges independently. You thrive in collaborative environments, easily engaging with diverse teams to achieve shared goals. Your dedication to operational excellence and compliance ensures that systems run smoothly and efficiently.
Required Skills
- Bachelor’s degree in Engineering
- 5–8+ years of automation engineering experience in a regulated environment (GMP preferred)
- Minimum of 3 years of experience with Syncade/MES Infrastructure, workflows, eBR design, and manufacturing process support
- Strong understanding of GxP compliance, data integrity, and change control processes
- Proven ability to independently troubleshoot and resolve complex technical issues
Preferred Skills
- Experience with Emerson DeltaV (DCS) integration and support
- Experience with AVEVA PI System for data collection and analytics
- Familiarity with Infobatch for batch reporting
- Participation in system upgrades, tech transfers, or manufacturing modernization initiatives
Job Level: Professional
Additional Information
The base compensation range for this role is: $93,000.00-$121,000.00
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year
- Employee Resource Groups participation
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our Biogen.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
See All 1,866+ Senior Web Engineer Jobs in North Carolina
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Find Senior Web Engineer JobsSenior Web Engineer Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Senior Web Engineer Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
- ALG Senior295

- Thermo Fisher Scientific61

- NVIDIA34

- Truist30

- Honeywell28

Top Industries Hiring
- Consulting & Professional Services360
- Technology & Software280
- Manufacturing144
- Construction & Real Estate135
- Banking & Financial Services96
What North Carolina Employers Look For
The qualifications that appear most often in senior web engineer jobs across North Carolina.
- 5 or more years of professional experience in web application development
- Proficiency in one or more modern frontend frameworks such as React, Vue, or Angular
- Strong command of TypeScript and JavaScript fundamentals
- Experience with RESTful or GraphQL API design and integration
- Familiarity with CI/CD pipelines, cloud infrastructure, and deployment workflows
- Bachelor's degree in computer science, software engineering, or a related technical field
Senior Web Engineer Jobs in North Carolina: Frequently Asked Questions
How many senior web engineer jobs are there in North Carolina?
There are 1,866+ senior web engineer openings in North Carolina on Migrate Mate as of June 2026, with the most roles in Charlotte, Raleigh, and Durham. New positions post regularly as employers across North Carolina hire.
How much do senior web engineers make in North Carolina?
Senior web engineers in North Carolina earn a median of about $96,610 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $54,450 for the lowest 10% to over $140,550 for the top 10%. Pay rises with experience, specialty, and employer.
Which North Carolina cities have the most senior web engineer jobs?
Charlotte, Raleigh, and Durham have the most senior web engineer openings in North Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire senior web engineers in North Carolina?
Employers hiring senior web engineers in North Carolina include ALG Senior, Thermo Fisher Scientific, and NVIDIA, based on current listings on Migrate Mate as of June 2026.
Are there remote senior web engineer jobs in North Carolina?
Yes. About 21% of senior web engineer openings tied to North Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in North Carolina metros.
How do I apply for senior web engineer jobs in North Carolina?
You can apply to senior web engineer jobs in North Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred North Carolina location, then apply to each one that fits.
See All 1,866+ Senior Web Engineer Jobs in North Carolina
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