Software Product Manager Jobs in San Francisco, CA
Software Product Manager jobs in San Francisco concentrate in SoMa, the Financial District, and Mission Bay, where enterprise software, fintech, and consumer tech companies cluster. Demand is strong year-round, and employers hiring right now include Rippling, Pinterest, and Netic. Scan the live roles below and apply to whichever ones fit.
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The Position
Technical Product Owner, RDT Lead – 3PD (Personalized, Predictive Patient Data)
The Opportunity
The Technical Product Owner, RDT Lead – 3PD drives the technical product strategy and delivery for Roche’s Patient Strategy data ecosystem. Combining strategic product ownership and delivery leadership, this role unifies internal and external data streams into a scalable, compliant engine that powers personalized healthcare experiences.
About the Ecosystem
3PD connects patients, providers, and operations through unified data, predictive analytics, and AI/ML capabilities. Spanning ingestion, integration, governance, and advanced decisioning, it empowers timely interventions to optimize patient treatment journeys.
The Technical Product Owner/RDT Lead evolves 3PD as an integrated enterprise platform—balancing immediate Patient Strategy needs with long-term scalability, interoperability, reliability, and reuse.
Key Responsibilities
- Product Vision & Strategy: Define and execute the 3PD strategy, roadmap, and backlog, translating business needs into scalable data capabilities and AI/ML enablement.
- Data Lifecycle Ownership: Provide technical leadership across acquisition, ingestion, processing, storage, and consumption to support end-user and downstream system needs.
- Vendor Data Acquisition: Lead technical onboarding of external data sources, including mapping, validation, reconciliation, quality, and operational readiness.
- System Integration & Enablement: Drive upstream and downstream integrations, making patient data available for operational systems, analytics, reporting, AI/ML, and decisioning platforms.
- Delivery Management: Lead end-to-end technical delivery across workstreams, managing scope, milestones, dependencies, risks, and cross-team handoffs.
- Data Quality & Reliability: Establish standards for data accuracy, timeliness, and completeness; implement monitoring, observability, and issue-remediation with engineering teams.
- Architecture & Strategy: Partner with architects to guide integration patterns, scalability, interoperability, and long-term sustainability while managing technical debt.
- Governance & Compliance: Embed data governance, lineage, privacy, consent, security, and regulatory requirements into product design and delivery.
- Dependency Management: Maintain an end-to-end view of dependencies across consuming products to prevent delivery bottlenecks.
- Stakeholder & Vendor Leadership: Build partnerships across Patient Strategy, business, DDA, architecture, engineering, and external vendors to drive alignment and resolve conflicts.
- Product Health & Improvement: Define metrics for product health, data quality, adoption, and operational stability to guide continuous improvement.
Who You Are
- Bachelor’s degree in IT, Computer Science, Data/Analytics, or a related field; an advanced degree or certifications (PMP/PgMP/Product) preferred.
- 10+ years leading complex technical integrations, enterprise data products, and cross-functional product delivery within large-scale IT environments.
- Demonstrated expertise owning data ecosystems—including vendor ingestion, data quality, governance, lineage, and enablement for analytics, AI/ML, and decisioning platforms.
- Strong technical fluency in cloud platforms, APIs, batch/event integrations, data pipelines, data modeling, and enterprise architecture patterns.
- Proven track record translating business needs into product roadmaps, navigating complex stakeholder environments, and driving cross-team execution.
- Solid background in data privacy, consent, security, and regulatory compliance for sensitive patient data environments.
Technical / Business Skills
- Strong knowledge of the end-to-end data lifecycle, including acquisition, ingestion, integration, transformation, quality, and consumption.
- Experience translating business and end-user needs into technical requirements, product roadmaps, and scalable data capabilities.
- Strong understanding of data quality, governance, lineage, privacy, consent, security, and regulatory requirements for sensitive patient data.
- Strong product and delivery management skills, including roadmap and backlog management, prioritization, dependency and risk management, and end-to-end delivery.
- Advanced analytical and problem-solving skills with the ability to evaluate technical options and drive decisions across complex, cross-functional environments.
Additional Qualifications
- Exceptional communication, facilitation, and negotiation skills, with the ability to drive consensus across business and technical stakeholders.
- Demonstrated ability to influence without direct authority and navigate complex cross-functional and vendor relationships.
- Strong leadership, coaching, and mentoring capabilities across product and delivery teams.
- Experience with Agile/product operating models and complex, multi-team technical delivery.
- Experience in pharmaceutical, healthcare, patient services, or other regulated data environments preferred.
- Experience enabling data for analytics, AI/ML, predictive capabilities, decisioning, or personalization is highly desirable.
The expected salary range for this position based on the primary location of South San Francisco, CA is $142,200 - $264,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
Relocation benefits are not available for this job posting.
#RDT2026
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
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Find Software Product Manager JobsSoftware Product Manager Job Market in San Francisco
Who's Hiring
- Rippling18

- Pinterest14

- Netic9N
- HARVEY9

- Genentech9

Top Industries Hiring
- Technology & Software32
- Consulting & Professional Services9
- Medical Devices5
- Science & Research5
- Artificial Intelligence5
Software Product Manager Jobs in San Francisco: Frequently Asked Questions
How do I get a software product manager job in San Francisco?
Focus your search on SoMa, Mission Bay, and the Financial District, where enterprise software, fintech, and consumer tech companies hire the most software product managers. Candidates who can demonstrate experience with agile delivery, cross-functional roadmap ownership, and data-informed prioritization stand out in this market. Targeting growth-stage startups alongside established technology firms broadens your options considerably in San Francisco.
Which companies hire software product managers in San Francisco?
San Francisco software product manager roles are posted by Rippling, Pinterest, and Netic and others right now, based on current listings on Migrate Mate as of September 2026. San Francisco draws a mix of global technology companies, well-funded startups, and fintech firms, giving software product managers a wide range of employer types and product domains to target.
Are there remote software product manager jobs in San Francisco?
Yes, software product management is one of the more remote-compatible professional roles given its emphasis on written communication, async collaboration, and digital tooling. About 74% of software product manager openings tied to San Francisco are remote or hybrid as of September 2026, reflecting how broadly technology employers here have adopted flexible arrangements. Strategic and analytical work tends to be the most location-flexible, while roles requiring regular stakeholder workshops often favor hybrid schedules.
How can I get a software product manager job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is moving into a software product manager role from an adjacent position such as business analyst, technical program coordinator, or associate product manager at a mid-size startup. San Francisco's density of early-stage companies means many actively hire APMs or promote internally from engineering and design. Building a portfolio of case studies that show product thinking, and engaging with local PM communities in SoMa and Mission Bay, gives candidates without formal PM titles a concrete edge.
Which industries hire the most software product managers in San Francisco?
The sectors hiring the most software product managers in San Francisco are Technology & Software, Consulting & Professional Services, and Medical Devices, based on current listings on Migrate Mate as of September 2026. San Francisco's concentration of venture-backed technology companies and established fintech headquarters makes those sectors the primary engines of local software product manager demand.
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