STEM OPT Safety Engineer Jobs
Safety Engineer roles qualify for the 24-month STEM OPT extension if your degree falls under an eligible CIP code in engineering or a related STEM field. Employers must be enrolled in E-Verify and sign a Form I-983 training plan outlining your engineering responsibilities and learning objectives.
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Get Access To All JobsINTRODUCTION
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
THE OPPORTUNITY
The Senior Safety Scientist within Global Patient Safety Science is an individual contributor who provides safety science and pharmacovigilance support to all products across the RevMed portfolio, which includes early and late phase development activities. The individual will be responsible for safety oversight of clinical studies, review and authoring of clinical trial protocols, IBs, ICFs, and DSURs. Additional safety related activities will involve medical review of individual case safety reports (ICSRs), safety surveillance of assigned products and active member of cross-functional teams. The Senior Safety Scientist will develop and maintain an understanding of the safety profile of the assigned product(s).
Responsibilities
- Proactive medical safety surveillance of ongoing clinical trials for identification and management of safety
- Prepare and present safety data summaries to internal and external stakeholders
- Risk management activities include, but are not limited to medical review of ICSRs, routine review of safety data and pertinent scientific literature articles
- Acquire and contribute knowledge of relevant drug class and/or competitor safety issues
- Identify potential clinical safety issues and recommend appropriate risk mitigation measures
- Involvement in preparation and maintenance of relevant sections of clinical trial protocols, IBs (including the reference safety information section), ICFs, DSURs, RMPs, CCDS, and labelling, as required
- Perform safety review of clinical protocols, Investigator's Brochure (IB), informed consent form (ICF) and other related documents to ensure alignment with the safety strategy and ensure the appropriateness of risk management strategies and risk communication
- Accountable for the safety components of study reports (i.e., CSRs), publications, aggregate reports, and other regulatory documents
- Conducts signal detection and evaluation activities for assigned products for the continuous benefit-risk evaluation throughout the product lifecycle and contributes/leads preparation for escalation to safety governance committees
- Supports implementation of decisions from the signal evaluation process, including updates to core safety information, Investigator’s Brochure and other key safety documents and deliverables
- Contributes to input related to regulatory filings, New Drug Applications [NDAs], Biologics License Applications [BLAs]), and responses to safety queries from third parties, such as regulatory agencies
- Establish and maintain collaborative working relationships with all key stakeholders (study team members, CROs, investigators, study sites, vendors, committees, etc.)
- Consistently comply with all governing laws, regulations, RevMed standard operating procedures (SOPs) and other guidelines
REQUIRED SKILLS, EXPERIENCE AND EDUCATION
- A relevant postgraduate qualification (e.g., MD, PharmD, PHD/MSc in a Life sciences discipline, or other post-graduate health professional qualifications)
- 3 or more years of drug development experience in the pharmaceutical or related industry with at least 1 year in drug safety
- Proven success in creating and sustaining strong relationships with internal and external business partners across an organization to create positive partnerships
- Broad understanding of the scientific aspects of safety, PV (including GVP, GCP), and clinical/patient risk management and safety operations
- Demonstrated ability to lead and influence, with and without authority, in a fast-paced environment
- Strong presentation skills, effective at summarizing and presenting the key considerations and decision points
- Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment
- Detail-oriented with ability prioritize tasks and function independently as appropriate
- Strong organizational skills and an ability to interpret, discuss, and report trial level data effectively and identify trends
- Excellent written and verbal communication skills
COMPENSATION
- Base Pay Salary Range: $120,000 - $150,000 USD
Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
INTRODUCTION
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
THE OPPORTUNITY
The Senior Safety Scientist within Global Patient Safety Science is an individual contributor who provides safety science and pharmacovigilance support to all products across the RevMed portfolio, which includes early and late phase development activities. The individual will be responsible for safety oversight of clinical studies, review and authoring of clinical trial protocols, IBs, ICFs, and DSURs. Additional safety related activities will involve medical review of individual case safety reports (ICSRs), safety surveillance of assigned products and active member of cross-functional teams. The Senior Safety Scientist will develop and maintain an understanding of the safety profile of the assigned product(s).
Responsibilities
- Proactive medical safety surveillance of ongoing clinical trials for identification and management of safety
- Prepare and present safety data summaries to internal and external stakeholders
- Risk management activities include, but are not limited to medical review of ICSRs, routine review of safety data and pertinent scientific literature articles
- Acquire and contribute knowledge of relevant drug class and/or competitor safety issues
- Identify potential clinical safety issues and recommend appropriate risk mitigation measures
- Involvement in preparation and maintenance of relevant sections of clinical trial protocols, IBs (including the reference safety information section), ICFs, DSURs, RMPs, CCDS, and labelling, as required
- Perform safety review of clinical protocols, Investigator's Brochure (IB), informed consent form (ICF) and other related documents to ensure alignment with the safety strategy and ensure the appropriateness of risk management strategies and risk communication
- Accountable for the safety components of study reports (i.e., CSRs), publications, aggregate reports, and other regulatory documents
- Conducts signal detection and evaluation activities for assigned products for the continuous benefit-risk evaluation throughout the product lifecycle and contributes/leads preparation for escalation to safety governance committees
- Supports implementation of decisions from the signal evaluation process, including updates to core safety information, Investigator’s Brochure and other key safety documents and deliverables
- Contributes to input related to regulatory filings, New Drug Applications [NDAs], Biologics License Applications [BLAs]), and responses to safety queries from third parties, such as regulatory agencies
- Establish and maintain collaborative working relationships with all key stakeholders (study team members, CROs, investigators, study sites, vendors, committees, etc.)
- Consistently comply with all governing laws, regulations, RevMed standard operating procedures (SOPs) and other guidelines
REQUIRED SKILLS, EXPERIENCE AND EDUCATION
- A relevant postgraduate qualification (e.g., MD, PharmD, PHD/MSc in a Life sciences discipline, or other post-graduate health professional qualifications)
- 3 or more years of drug development experience in the pharmaceutical or related industry with at least 1 year in drug safety
- Proven success in creating and sustaining strong relationships with internal and external business partners across an organization to create positive partnerships
- Broad understanding of the scientific aspects of safety, PV (including GVP, GCP), and clinical/patient risk management and safety operations
- Demonstrated ability to lead and influence, with and without authority, in a fast-paced environment
- Strong presentation skills, effective at summarizing and presenting the key considerations and decision points
- Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment
- Detail-oriented with ability prioritize tasks and function independently as appropriate
- Strong organizational skills and an ability to interpret, discuss, and report trial level data effectively and identify trends
- Excellent written and verbal communication skills
COMPENSATION
- Base Pay Salary Range: $120,000 - $150,000 USD
Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
See all 124+ STEM OPT Safety Engineer Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new STEM OPT Safety Engineer Jobs.
Get Access To All JobsTips for Finding STEM OPT Authorization as a Safety Engineer
Verify your CIP code matches safety engineering
Check that your degree's CIP code appears on the DHS STEM Designated Degree Program list before applying. Industrial, environmental, and occupational health engineering codes typically qualify, but your DSO confirms eligibility and updates your I-20.
Build an I-983 that reflects real engineering work
Safety Engineer training plans must document specific engineering tasks, not generic job duties. List hazard analysis methods, regulatory compliance work, or process safety reviews you'll perform so the plan withstands USCIS scrutiny.
Filter employers by E-Verify enrollment status
STEM OPT employers must be enrolled in E-Verify before you start work. Migrate Mate surfaces only E-Verify-enrolled employers on its job board, so you can target Safety Engineer roles without manually checking each company's compliance status.
Target industries with established OSHA compliance teams
Manufacturing, construction, and chemical processing companies hire Safety Engineers under structured compliance programs and are familiar with the I-983 training plan requirement. These employers tend to move faster through the STEM OPT filing process than companies hiring their first OPT student.
Use OFLC Wage Search to benchmark your offer
STEM OPT requires your pay to equal the actual wage paid to comparable workers. Look up the prevailing wage for your job title and work location in OFLC Wage Search before accepting an offer to confirm the employer meets the requirement.
File your STEM OPT extension 90 days early
USCIS recommends submitting your STEM OPT extension application up to 90 days before your initial OPT expires. Your DSO must update your I-20 first, so start the I-983 review with your employer at least 30 days before that window opens.
Frequently Asked Questions
Does a Safety Engineer role qualify for the STEM OPT extension?
Yes, if your underlying degree carries an eligible CIP code under the DHS STEM Designated Degree Program list. Degrees in industrial engineering, occupational safety, environmental engineering, and related STEM fields typically qualify. Your DSO verifies eligibility and authorizes the extension on your I-20. The role itself must involve applying STEM knowledge directly, not just administrative safety coordination.
What must an employer include in the I-983 training plan for a Safety Engineer?
The I-983 must describe specific STEM learning objectives tied to your Safety Engineer duties, such as conducting hazard and operability studies, developing process safety management programs, or applying engineering controls to OSHA standards. Generic job descriptions aren't sufficient. Both you and your employer sign the form, and your DSO must approve it before your STEM OPT extension begins. USCIS can request the plan during a site visit.
Does my Safety Engineer employer need to be enrolled in E-Verify?
Yes. E-Verify enrollment is a legal requirement for any employer hiring a STEM OPT student, and you can't start work until it's confirmed. You can check an employer's status through the E-Verify employer search tool before accepting an offer. Migrate Mate filters its Safety Engineer listings to show only E-Verify-enrolled employers, which removes this verification step from your job search.
What happens to my STEM OPT authorization if my Safety Engineer employer loses E-Verify access?
If your employer's E-Verify enrollment lapses or is terminated, your STEM OPT authorization is no longer valid and you must stop working. You have a 60-day grace period to find a new E-Verify-enrolled employer and transfer your OPT authorization. Report any employer change to your DSO immediately and file an updated I-983 with the new employer before resuming work.
Can I change Safety Engineer employers mid-STEM OPT period?
Yes, you can change employers during your STEM OPT extension, but you must report the change to your DSO within 10 days and submit a new I-983 training plan signed by the incoming employer. The new employer must be enrolled in E-Verify. You cannot work for the new employer until your DSO has processed the update and your SEVIS record reflects the change.