Systems Engineer Jobs in Cambridge, MA

Systems Engineer jobs in Cambridge, Massachusetts are concentrated in Kendall Square, East Cambridge, and the MIT corridor, where demand from defense contractors, life sciences firms, and tech companies keeps openings active year-round. Employers hiring right now include Draper, Lila Sciences, and Philips. Find a role that fits below and apply directly.

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Overview

Open roles180+
Top employerDraper
Work type75% On-site
Top credentialBachelor's degree in Physics
Companies hiring5

Showing 5 of 180+ Systems Engineer jobs

Halobraid
Principal Mechanical Engineer / Systems Engineer
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Halobraid
New 8h ago
Principal Mechanical Engineer / Systems Engineer
Halobraid
Cambridge, Massachusetts
Engineering (Non-Software)
Mechanical Engineering
Specialized Engineering
On-Site

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Draper
Sr. Product Engineer (Systems Assembly)
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Draper
Added 1d ago
Sr. Product Engineer (Systems Assembly)
Draper
Cambridge, Massachusetts
Compliance & Risk
Cybersecurity
Security Engineering
$63k - $238k/yr
Bachelor's degree in mechanical engineering
1,001-5,000

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Lila Sciences
Staff / Principal Automated Systems Engineer
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Lila Sciences
Added 5d ago
Staff / Principal Automated Systems Engineer
Lila Sciences
Cambridge, Massachusetts
Specialized Engineering
Mechanical Engineering
Electrical Engineering
Industrial & Manufacturing Engineering
Engineering (Non-Software)
Manufacturing Engineering
$163k - $228k/yr
On-Site
Bachelor's

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Lila Sciences
Senior Automated Systems Engineer
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Lila Sciences
Added 6d ago
Senior Automated Systems Engineer
Lila Sciences
Cambridge, Massachusetts
Specialized Engineering
Quality Assurance & Testing (QA Testing)
Manufacturing Operations
Engineering (Non-Software)
Automation QA
$119k - $182k/yr
On-Site
None

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Draper
Systems Integration & Test Engineer
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Draper
Added 6d ago
Systems Integration & Test Engineer
Draper
Cambridge, Massachusetts
Engineering (Non-Software)
Product Management
Technical Product & Program Management
$63k - $150k/yr
Bachelor's degree in mechanical engineering
1,001-5,000

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See All 180+ Systems Engineer Jobs in Cambridge

Find roles in Cambridge that match your experience and apply in just a few clicks.

Find Systems Engineer Jobs

Systems Engineer Job Market in Cambridge

Who's Hiring

  • Draper
    Draper98
  • Lila Sciences
    Lila Sciences33
  • Philips
    Philips16
  • Halobraid
    Halobraid16
  • Flagship Pioneering
    Flagship Pioneering16

Top Industries Hiring

  • Biotechnology & Pharmaceuticals

Systems Engineer Jobs in Cambridge: Frequently Asked Questions

How do I get a systems engineer job in Cambridge?

Focus your search on Kendall Square and East Cambridge, where defense contractors, biotech companies, and research-driven tech firms cluster. Employers in Cambridge tend to value hands-on experience with complex systems integration, familiarity with government or regulated environments, and the ability to work alongside research teams. Tailoring your application to show cross-functional technical work gives you a clear edge in this market.

Which companies hire systems engineers in Cambridge?

Cambridge systems engineer roles are posted by Draper, Lila Sciences, and Philips and others right now, based on current listings on Migrate Mate as of August 2026. Cambridge attracts a mix of large defense primes, university-affiliated research organizations, and venture-backed hardware and life sciences companies, all of which hire systems engineers at multiple levels.

Are there remote systems engineer jobs in Cambridge?

Yes, though availability depends heavily on the role. Systems engineering work that involves physical hardware, lab environments, or classified facilities is typically on-site, while model-based systems engineering, documentation, and analysis work can be done remotely. About 25% of systems engineer openings tied to Cambridge are remote or hybrid as of August 2026, with the most flexibility found in software-defined systems and enterprise architecture roles at Cambridge tech companies.

How can I get a systems engineer job in Cambridge with little or no experience?

The most realistic entry path in Cambridge is through a junior or associate systems engineer role at one of the many defense or aerospace contractors based in Kendall Square and East Cambridge, several of which recruit directly from MIT and Harvard. Internships or co-ops at these firms convert into full-time offers regularly. Gaining familiarity with model-based systems engineering tools and contributing to open-source hardware or systems projects strengthens an entry-level profile considerably.

Which industries hire the most systems engineers in Cambridge?

The sectors hiring the most systems engineers in Cambridge are Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of August 2026. Cambridge's dense concentration of defense contractors, biotech firms, and university research spinouts creates consistent demand for systems engineers who can work at the intersection of hardware, software, and regulated technical environments.

See All 180+ Systems Engineer Jobs in Cambridge

Find roles in Cambridge that match your experience and apply in just a few clicks.

Find Systems Engineer Jobs