Process Engineer Jobs in Massachusetts
Process Engineer jobs in Massachusetts are in strong demand, with active hiring in biotechnology, pharmaceuticals, semiconductor manufacturing, and defense systems, at levels from entry-level associates through senior and principal engineers. Boston, Cambridge, and Lowell are the primary hiring centers, home to major employers such as Raytheon Technologies, Bristol Myers Squibb, and Analog Devices that maintain deep process engineering workforces. The most sought-after specialties in Massachusetts right now are bioprocess and cell therapy manufacturing, semiconductor fabrication, and chemical process optimization. Find a role that fits below and apply directly.
Find Process Engineer JobsOverview
Open roles103+
Top employerMIT Lincoln Laboratory
Top cityBillerica, MA
Cities hiring47
Work type83% On-site
Top industryManufacturing
Showing 5 of 103+ Process Engineer jobs
Sr. Process Engineer - Assay Manufacturing
We won't show you this job again
Added 1d ago
Quanterix
Sr. Process Engineer - Assay Manufacturing
Billerica, Massachusetts
Added 1d ago
C
Manufacturing Engineer – Equipment, Process & Quality
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C
Added 1d ago
Crusader Paper Company, Inc.
Manufacturing Engineer – Equipment, Process & Quality
North Andover, Massachusetts
Added 1d ago
Senior Braiding/ Process Engineer
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Added 1d ago
Titeflex Commercial Inc.
Senior Braiding/ Process Engineer
Springfield, Massachusetts
Added 1d ago
Senior Manufacturing Engineer – Process & NPI
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Added 1d ago
Saraca Solutions Inc.
Senior Manufacturing Engineer – Process & NPI
Devens, Massachusetts
Added 1d ago
Staff Engineer, Process Sustaining Engineering
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Added 1d ago
Analog Devices
Staff Engineer, Process Sustaining Engineering
Wilmington, Massachusetts
Added 1d ago
Added 1d ago
Sr. Process Engineer - Assay Manufacturing
Quanterix·Billerica, Massachusetts
Job functions:
$100k - $120k/yr
Master's degree
201-500 employees
Job Description
Sr. Process Engineer - Assay Manufacturing
Billerica, MA
Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its proprietary Simoa® technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades. In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company®, adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue—advancing precision medicine from discovery to diagnostics.
ROLE SUMMARY:
We are seeking a highly skilled Sr. Process Engineer - Assay Manufacturing to lead the development, scale-up, and optimization of our diagnostic assay manufacturing lines. The ideal candidate will bridge the gap between R&D and commercial production, ensuring that all manufacturing processes are robust, scalable, and fully compliant with cGMP and ISO 13485 standards. You will be responsible for troubleshooting complex technical issues, implementing automation, and driving continuous improvement to ensure the highest quality of our diagnostic products.
WHAT YOU’LL DO:
- Process Development & Scale-Up: Design, develop, and validate manufacturing processes for complex biological assays, moving products from R&D prototypes to full-scale commercial production.
- cGMP Compliance: Ensure all manufacturing activities, equipment, and documentation strictly adhere to current Good Manufacturing Practices (cGMP), FDA regulations, and ISO standards.
- Equipment Validation (IQ/OQ/PQ): Lead the installation, operational, and performance qualification of automated liquid handlers, plate washers, and other specialized assay manufacturing equipment.
- Technical Troubleshooting: Act as the subject matter expert (SME) for root-cause analysis of process deviations and yield excursions. Implement effective Corrective and Preventive Actions (CAPA).
- Documentation: Author and review Standard Operating Procedures (SOPs), Batch Records, Work Instructions, and Process Validation protocols/reports.
- Continuous Improvement: Identify opportunities for cost reduction and efficiency gains through Lean Manufacturing, Six Sigma methodologies, and the integration of new technologies or automation.
- Cross-Functional Collaboration: Work closely with R&D, Quality Assurance, and Supply Chain to ensure seamless technology transfers and product launches
BASIC QUALIFICATIONS:
- Education: Bachelor’s degree in Chemical Engineering, Bioengineering, Biotechnology, or a related scientific discipline. (Master’s preferred).
- Experience: Minimum 8 years of experience in a process engineering role within a cGMP-regulated environment (e.g., IVD, medical device, or pharmaceutical industry).
- Regulatory Knowledge: Deep familiarity with FDA 21 CFR Part 820 and/or ISO 13485 requirements.
PREFERRED QUALIFICATIONS:
- Direct experience with assay chemistry, reagent formulation, or diagnostic kit assembly
- Hands-on experience with automated manufacturing platforms and liquid handling systems
- Strong understanding of Statistical Process Control (SPC) and Design of Experiments (DoE).
- Experience with Six Sigma or Lean Manufacturing certification (Green/Black Belt).
- Proficiency in statistical software such as Minitab or JMP.
- Background in lyophilization processes or coating technologies.
- Strong project management skills and the ability to lead cross-functional teams.
EXPECTATIONS, COMPETENCIES, SKILLS & ABILITIES:
- Strong judgment, accountability, and attention to detail in a regulated manufacturing environment.
- Effective communication and collaboration across technical and cross-functional teams.
- Strong problem-solving and decision-making skills with the ability to assess risk and recommend practical solutions.
- Ability to manage multiple priorities, adapt to changing business needs, and meet deadlines.
- Professionalism, sound judgment, and the ability to handle sensitive information with discretion.
- Continuous learning mindset with a focus on quality, process improvement, and operational excellence.
- Must be able to work in a cleanroom environment (ISO 7/8).
- Occasional lifting of equipment (up to 25 lbs) may be required.
- Adherence to strict gowning and safety protocols is mandatory.
- Work location: Billerica, MA (Onsite 5 days)
- Travel 10%
WHY YOU’LL LIKE WORKING WITH US:
Our Technology:
From discovery to diagnostics, Quanterix’s ultrasensitive biomarker detection is fueling breakthroughs only made possible through its unparalleled sensitivity and flexibility. Simoa® technology has delivered the gold standard for earlier biomarker detection in blood, serum or plasma, with the ability to quantify proteins that are far lower than the Level of Quantification (LoQ). Our industry-leading precision instruments, digital immunoassay technology and CLIA-certified Accelerator laboratory have supported research that advances disease understanding and management in neurology, oncology, immunology, cardiology, and infectious disease.
Akoya Biosciences, a Quanterix company, is The Spatial Biology Company®—bringing tissue context to life through high-resolution, single-cell imaging. Akoya’s spatial phenotyping platforms help researchers visualize and measure how cells organize and interact within tissue to influence disease progression and therapeutic response. From discovery through clinical research, Akoya offers a full continuum of solutions, including PhenoCycler®, PhenoImager® Fusion and HT, and PhenoCode™ Panels. As part of Quanterix, Akoya complements a leading portfolio of ultra-sensitive biomarker detection technologies, together enabling a more complete view of biology and disease across both tissue and blood.
Our Commitment to Employees:
At Quanterix, our values are based on: Team, Innovation, Customer and Owner.
Team: Challenge assumptions, not the person. Respect diversity of thought and hold ourselves to lofty standards
Innovation: Stay curious, experiment, create and change
Customer: Prioritize and celebrate these pioneers by doing our best to deliver on commitments
Owner: Act with high integrity and in the best interest of Quanterix. Take measured risks and learn from their success and failures.
We reward and recognize our employees by offering competitive compensation and a 401k plan with employer match, as well as competitive health, dental, and vision benefits for employees and their dependents. We also offer an unlimited vacation policy to all exempt employees, and a generous PTO policy for non-exempt employees. All employees are eligible for equity, employee stock purchase plan, a performance bonus, and 1:1 financial counseling/planning. We also offer Tuition Assistance. We have a free, state-of-the-art onsite fitness center for all employees. To keep you fueled up, we provide onsite employees free snacks and drinks every day!
DIVERSE & INCLUSIVE WORKPLACE:
Quanterix is committed to a Diverse and Inclusive workplace. We strive to recruit candidates who will bring inclusive mindsets and contribute to our values.
Quanterix is an Equal Opportunity Employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Quanterix will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Quanterix
Sr. Process Engineer - Assay Manufacturing
Billerica, Massachusetts
Added 1d ago201-500 employees
Job functions:
$100k - $120k/yr
Master's degree
Job Description
Sr. Process Engineer - Assay Manufacturing
Billerica, MA
Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its proprietary Simoa® technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades. In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company®, adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue—advancing precision medicine from discovery to diagnostics.
ROLE SUMMARY:
We are seeking a highly skilled Sr. Process Engineer - Assay Manufacturing to lead the development, scale-up, and optimization of our diagnostic assay manufacturing lines. The ideal candidate will bridge the gap between R&D and commercial production, ensuring that all manufacturing processes are robust, scalable, and fully compliant with cGMP and ISO 13485 standards. You will be responsible for troubleshooting complex technical issues, implementing automation, and driving continuous improvement to ensure the highest quality of our diagnostic products.
WHAT YOU’LL DO:
- Process Development & Scale-Up: Design, develop, and validate manufacturing processes for complex biological assays, moving products from R&D prototypes to full-scale commercial production.
- cGMP Compliance: Ensure all manufacturing activities, equipment, and documentation strictly adhere to current Good Manufacturing Practices (cGMP), FDA regulations, and ISO standards.
- Equipment Validation (IQ/OQ/PQ): Lead the installation, operational, and performance qualification of automated liquid handlers, plate washers, and other specialized assay manufacturing equipment.
- Technical Troubleshooting: Act as the subject matter expert (SME) for root-cause analysis of process deviations and yield excursions. Implement effective Corrective and Preventive Actions (CAPA).
- Documentation: Author and review Standard Operating Procedures (SOPs), Batch Records, Work Instructions, and Process Validation protocols/reports.
- Continuous Improvement: Identify opportunities for cost reduction and efficiency gains through Lean Manufacturing, Six Sigma methodologies, and the integration of new technologies or automation.
- Cross-Functional Collaboration: Work closely with R&D, Quality Assurance, and Supply Chain to ensure seamless technology transfers and product launches
BASIC QUALIFICATIONS:
- Education: Bachelor’s degree in Chemical Engineering, Bioengineering, Biotechnology, or a related scientific discipline. (Master’s preferred).
- Experience: Minimum 8 years of experience in a process engineering role within a cGMP-regulated environment (e.g., IVD, medical device, or pharmaceutical industry).
- Regulatory Knowledge: Deep familiarity with FDA 21 CFR Part 820 and/or ISO 13485 requirements.
PREFERRED QUALIFICATIONS:
- Direct experience with assay chemistry, reagent formulation, or diagnostic kit assembly
- Hands-on experience with automated manufacturing platforms and liquid handling systems
- Strong understanding of Statistical Process Control (SPC) and Design of Experiments (DoE).
- Experience with Six Sigma or Lean Manufacturing certification (Green/Black Belt).
- Proficiency in statistical software such as Minitab or JMP.
- Background in lyophilization processes or coating technologies.
- Strong project management skills and the ability to lead cross-functional teams.
EXPECTATIONS, COMPETENCIES, SKILLS & ABILITIES:
- Strong judgment, accountability, and attention to detail in a regulated manufacturing environment.
- Effective communication and collaboration across technical and cross-functional teams.
- Strong problem-solving and decision-making skills with the ability to assess risk and recommend practical solutions.
- Ability to manage multiple priorities, adapt to changing business needs, and meet deadlines.
- Professionalism, sound judgment, and the ability to handle sensitive information with discretion.
- Continuous learning mindset with a focus on quality, process improvement, and operational excellence.
- Must be able to work in a cleanroom environment (ISO 7/8).
- Occasional lifting of equipment (up to 25 lbs) may be required.
- Adherence to strict gowning and safety protocols is mandatory.
- Work location: Billerica, MA (Onsite 5 days)
- Travel 10%
WHY YOU’LL LIKE WORKING WITH US:
Our Technology:
From discovery to diagnostics, Quanterix’s ultrasensitive biomarker detection is fueling breakthroughs only made possible through its unparalleled sensitivity and flexibility. Simoa® technology has delivered the gold standard for earlier biomarker detection in blood, serum or plasma, with the ability to quantify proteins that are far lower than the Level of Quantification (LoQ). Our industry-leading precision instruments, digital immunoassay technology and CLIA-certified Accelerator laboratory have supported research that advances disease understanding and management in neurology, oncology, immunology, cardiology, and infectious disease.
Akoya Biosciences, a Quanterix company, is The Spatial Biology Company®—bringing tissue context to life through high-resolution, single-cell imaging. Akoya’s spatial phenotyping platforms help researchers visualize and measure how cells organize and interact within tissue to influence disease progression and therapeutic response. From discovery through clinical research, Akoya offers a full continuum of solutions, including PhenoCycler®, PhenoImager® Fusion and HT, and PhenoCode™ Panels. As part of Quanterix, Akoya complements a leading portfolio of ultra-sensitive biomarker detection technologies, together enabling a more complete view of biology and disease across both tissue and blood.
Our Commitment to Employees:
At Quanterix, our values are based on: Team, Innovation, Customer and Owner.
Team: Challenge assumptions, not the person. Respect diversity of thought and hold ourselves to lofty standards
Innovation: Stay curious, experiment, create and change
Customer: Prioritize and celebrate these pioneers by doing our best to deliver on commitments
Owner: Act with high integrity and in the best interest of Quanterix. Take measured risks and learn from their success and failures.
We reward and recognize our employees by offering competitive compensation and a 401k plan with employer match, as well as competitive health, dental, and vision benefits for employees and their dependents. We also offer an unlimited vacation policy to all exempt employees, and a generous PTO policy for non-exempt employees. All employees are eligible for equity, employee stock purchase plan, a performance bonus, and 1:1 financial counseling/planning. We also offer Tuition Assistance. We have a free, state-of-the-art onsite fitness center for all employees. To keep you fueled up, we provide onsite employees free snacks and drinks every day!
DIVERSE & INCLUSIVE WORKPLACE:
Quanterix is committed to a Diverse and Inclusive workplace. We strive to recruit candidates who will bring inclusive mindsets and contribute to our values.
Quanterix is an Equal Opportunity Employer and does not discriminate based on race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status. Quanterix will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
See All 103+ Process Engineer Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Process Engineer JobsProcess Engineer Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Billerica
8 jobsLexington
8 jobsCambridge
7 jobsBoston
5 jobsNorwood
5 jobsWoburn
4 jobsSpringfield
4 jobsDevens
3 jobsAndover
3 jobsGloucester
3 jobsWilmington
3 jobsDalton
2 jobsHudson
2 jobsLowell
2 jobsNatick
2 jobsOrange
2 jobsBedford
2 jobsBeverly
2 jobsConcord
2 jobsWaltham
2 jobsWebster
2 jobsMansfield
2 jobsChelmsford
2 jobsNewburyport
2 jobsLee
1 jobAthol
1 jobRaynham
1 jobSudbury
1 jobTaunton
1 jobAmesbury
1 jobChicopee
1 jobWestford
1 jobFairhaven
1 jobStoughton
1 jobWorcester
1 jobBurlington
1 jobFramingham
1 jobLeominster
1 jobMiddleboro
1 jobPlainville
1 jobSomerville
1 jobMarlborough
1 jobNew Bedford
1 jobWestborough
1 jobSouth Boston
1 jobNorth Andover
1 jobSouth Grafton
1 jobProcess Engineer Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Manufacturing
- Electronics & Hardware
- Biotechnology & Pharmaceuticals
- Consulting & Professional Services
- Science & Research
What Massachusetts Employers Look For
The qualifications that appear most often in process engineer jobs across Massachusetts.
- Bachelor's degree in chemical, mechanical, or industrial engineering from an accredited program
- Hands-on experience with process validation, scale-up, or continuous improvement in a regulated environment
- Familiarity with FDA cGMP or ISO manufacturing standards common in Massachusetts life sciences facilities
- Proficiency with statistical process control tools such as Minitab or Six Sigma methodologies
- Experience with process simulation software or PLC-based control systems used in advanced manufacturing
- Strong cross-functional communication skills for working with quality, operations, and R&D teams
Process Engineer Jobs in Massachusetts: Frequently Asked Questions
How do you become a process engineer in Massachusetts?
Most process engineer roles in Massachusetts require a bachelor's degree in chemical, mechanical, or industrial engineering from an accredited program. Massachusetts does not require a state-issued process engineering license for most industry roles, though engineers who sign off on public-works projects may pursue licensure through the Massachusetts Board of Registration of Professional Engineers and Land Surveyors. Employers in the life sciences corridor frequently prioritize candidates with cGMP training or process validation experience alongside their degree.
Which companies hire process engineers in Massachusetts?
Employers hiring process engineers in Massachusetts right now include MIT Lincoln Laboratory, Draper, and Analog Devices, based on current listings on Migrate Mate as of August 2026. Massachusetts's dense concentration of biopharmaceutical manufacturers, defense contractors, and semiconductor firms means demand is spread across both the Greater Boston area and suburban corridors like Route 128 and the Merrimack Valley.
Which Massachusetts cities have the most process engineer jobs?
Billerica, Lexington, and Cambridge account for the largest share of process engineer openings in Massachusetts. Greater Boston and Cambridge anchor the market through their pharmaceutical, biotech, and research institution campuses, while Lowell and the surrounding Merrimack Valley corridor draw openings from semiconductor manufacturers and defense systems companies that have operated there for decades.
Are there remote process engineer jobs in Massachusetts?
Yes, but they're rare. Process engineering is largely hands-on work tied to physical equipment, production lines, and regulated manufacturing floors, so most roles require consistent on-site presence. About 17% of process engineer openings tied to Massachusetts are remote or hybrid as of August 2026, and the positions that do offer flexibility tend to cover process documentation, data analysis, or project coordination rather than direct floor operations.
How can I get hired as a process engineer in Massachusetts with little or no experience?
The most realistic entry path is a new-graduate or rotational engineering program at one of Massachusetts's large life sciences or advanced manufacturing employers, where candidates with a relevant engineering degree move through hands-on process assignments before settling into a specialty. Companies in the Route 128 biotech corridor and Merrimack Valley semiconductor sector regularly post associate process engineer and manufacturing engineer titles aimed at recent graduates. Building familiarity with cGMP documentation, statistical process control, or process simulation software, and pursuing a Lean or Six Sigma certificate, gives candidates a clear edge for Massachusetts openings.
Where can I find and apply to process engineer jobs in Massachusetts?
You can find and apply to process engineer jobs in Massachusetts on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the available roles, identify the ones that match your background and target industry, and apply directly to each one that fits.
See All 103+ Process Engineer Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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