TN Visa Medical Director Oncology Jobs
Medical Director Oncology roles qualify for TN visa sponsorship under the USMCA treaty's physician category, giving Canadian and Mexican oncology leaders a cap-free path to U.S. leadership positions. Your employer files the TN petition directly, with no lottery and no annual wait for Canadian citizens.
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Get Access To All JobsINTRODUCTION
Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
ROLE AND RESPONSIBILITIES
This job provides clinical, scientific, and strategic leadership for clinical development programs, owns clinical development strategy for assigned programs and leads the design, execution, and interpretation of clinical studies. Denali is seeking a physician leader (MD or MD/PhD) with training in hematology/oncology (adult or pediatric) or neuro-oncology to provide clinical, scientific, and strategic leadership for oncology programs leveraging Denali’s Transport Vehicle (TV) platform.
Denali’s Transport Vehicle platform enables targeted delivery of therapeutics across biological barriers, creating new possibilities for treating cancers with limited therapeutic access, including tumors involving the central nervous system.
This individual will play a key role in advancing innovative therapies designed to address critical challenges in oncology, including drug delivery to the central nervous system and tumors with high unmet need. In addition to the focus in oncology, this role has the ability to grow across different therapeutic areas alongside our rapidly growing portfolio.
Key Accountabilities / Core Job Responsibilities:
- Contribute to the development and execution of clinical development strategies for oncology programs leveraging the Transport Vehicle platform
- Provide clinical and scientific leadership across study design, execution, analysis, interpretation, and reporting of early- and late-phase oncology trials
- Lead development of clinical protocols, amendments, investigator brochures, and clinical study reports
- Provide medical monitoring support, including evaluation of safety, pharmacology, and efficacy
- Partner cross-functionally with Translational Sciences, Clinical Pharmacology, Regulatory Affairs, and other functions to integrate biomarker and translational strategies
- Support clinical-regulatory strategy and interactions with health authorities
- Engage with external experts, investigators, and advisory boards in oncology and neuro-oncology
- Contribute to biomarker development, patient selection strategies, and innovative trial designs
- Prepare scientific communications, including presentations and publications
- Contribute to lifecycle planning and evaluation of new oncology development opportunities
- Leads one or more oncology clinical programs with accountability for program-level strategy, execution, and delivery
- Independently drives clinical trial activities while contributing to broader strategic discussions
- Applies clinical expertise in hematology/oncology or neuro-oncology to inform study design, endpoints, and patient selection
- Operates as a key clinical lead with increasing influence on program direction
BASIC QUALIFICATIONS
- MD or MD/PhD with board certification or eligibility in Hematology/Oncology (adult or pediatric) or Neuro-Oncology
- ~3+ years of clinical development experience in industry or equivalent clinical/academic research experience (e.g., fellowship/post-fellowship research, junior faculty)
- Strong scientific background in cancer biology, translational sciences or clinical trial design
- Demonstrated ability to lead program-level activities and collaborate effectively
COMPENSATION
- Salary Range: $272,000.00 to $336,000.00. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
INTRODUCTION
Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
ROLE AND RESPONSIBILITIES
This job provides clinical, scientific, and strategic leadership for clinical development programs, owns clinical development strategy for assigned programs and leads the design, execution, and interpretation of clinical studies. Denali is seeking a physician leader (MD or MD/PhD) with training in hematology/oncology (adult or pediatric) or neuro-oncology to provide clinical, scientific, and strategic leadership for oncology programs leveraging Denali’s Transport Vehicle (TV) platform.
Denali’s Transport Vehicle platform enables targeted delivery of therapeutics across biological barriers, creating new possibilities for treating cancers with limited therapeutic access, including tumors involving the central nervous system.
This individual will play a key role in advancing innovative therapies designed to address critical challenges in oncology, including drug delivery to the central nervous system and tumors with high unmet need. In addition to the focus in oncology, this role has the ability to grow across different therapeutic areas alongside our rapidly growing portfolio.
Key Accountabilities / Core Job Responsibilities:
- Contribute to the development and execution of clinical development strategies for oncology programs leveraging the Transport Vehicle platform
- Provide clinical and scientific leadership across study design, execution, analysis, interpretation, and reporting of early- and late-phase oncology trials
- Lead development of clinical protocols, amendments, investigator brochures, and clinical study reports
- Provide medical monitoring support, including evaluation of safety, pharmacology, and efficacy
- Partner cross-functionally with Translational Sciences, Clinical Pharmacology, Regulatory Affairs, and other functions to integrate biomarker and translational strategies
- Support clinical-regulatory strategy and interactions with health authorities
- Engage with external experts, investigators, and advisory boards in oncology and neuro-oncology
- Contribute to biomarker development, patient selection strategies, and innovative trial designs
- Prepare scientific communications, including presentations and publications
- Contribute to lifecycle planning and evaluation of new oncology development opportunities
- Leads one or more oncology clinical programs with accountability for program-level strategy, execution, and delivery
- Independently drives clinical trial activities while contributing to broader strategic discussions
- Applies clinical expertise in hematology/oncology or neuro-oncology to inform study design, endpoints, and patient selection
- Operates as a key clinical lead with increasing influence on program direction
BASIC QUALIFICATIONS
- MD or MD/PhD with board certification or eligibility in Hematology/Oncology (adult or pediatric) or Neuro-Oncology
- ~3+ years of clinical development experience in industry or equivalent clinical/academic research experience (e.g., fellowship/post-fellowship research, junior faculty)
- Strong scientific background in cancer biology, translational sciences or clinical trial design
- Demonstrated ability to lead program-level activities and collaborate effectively
COMPENSATION
- Salary Range: $272,000.00 to $336,000.00. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
See all 75+ Medical Director Oncology jobs
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Get Access To All JobsTips for Finding TN Visa Sponsorship as a Medical Director Oncology
Verify your medical credentials align with TN
TN classification for physicians requires a valid license in your home country plus proof of qualification to practice in the destination U.S. state. Gather your medical degree, board certifications, and provincial or national license before approaching employers.
Target academic medical centers and NCI-designated cancer centers
Health systems affiliated with National Cancer Institute-designated programs routinely hire foreign-trained oncology directors and have established TN sponsorship workflows. Their legal teams understand physician TN requirements, which shortens the negotiation and filing process considerably.
Search TN-sponsoring oncology employers on Migrate Mate
Use Migrate Mate to filter Medical Director Oncology roles by employers with recent visa filings, so you're applying where visa sponsorship experience already exists rather than educating hiring managers about the process from scratch.
Clarify state medical licensure timing with your employer
You don't need a full U.S. medical license before the TN petition is approved, but many hospitals require licensure before your start date. Negotiate a realistic start date that accounts for state medical board processing, which can run 90 to 120 days.
Confirm the employer will file by mail, not at the border
Medical Director Oncology roles often involve credentialing and background checks that delay start dates, making USCIS mail-in petitions the safer filing route. Canadian citizens can also use port-of-entry TN admission, but that approach doesn't give you a stamped approval document most hospitals require for privileging.
Document your specialty scope to prevent RFE delays
USCIS scrutinizes physician TN petitions where the role blends administrative leadership with direct patient care. Your offer letter should explicitly describe oncology-specific duties and confirm the position requires a physician's medical expertise, not just general management skills.
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Find Medical Director Oncology JobsMedical Director Oncology TN Visa: Frequently Asked Questions
Does a Medical Director Oncology role qualify for TN visa status?
Yes, provided the position genuinely requires a licensed physician with oncology expertise. The TN physician category covers roles where medical training and licensure are prerequisites, not incidental. Roles that are purely administrative without requiring an active medical license may face additional USCIS scrutiny, so your offer letter needs to clearly articulate the clinical and scientific basis of the position.
How does TN visa sponsorship compare to H-1B for this role?
For Canadian citizens, TN is almost always faster and more predictable than H-1B. There is no lottery, no annual cap, and no multi-month wait. H-1B requires a cap-subject registration and can take six months or more before a start date is possible. Mexican nationals face a TN allocation limit, but TN processing is still substantially faster than H-1B for roles that qualify under the physician category.
How can I find Medical Director Oncology jobs with TN visa sponsorship?
Migrate Mate is built specifically for this search. You can filter by TN visa sponsorship and target Medical Director Oncology roles at employers who have already demonstrated willingness to sponsor. That filters out the dead ends you'd encounter applying broadly and then discovering a hospital's legal team has never handled a TN petition.
Can a Mexican physician get TN sponsorship for an oncology director role?
Yes, but the process differs from the Canadian path. Mexican TN applicants must apply at a U.S. consulate in Mexico rather than at a port of entry, and Mexico's TN allocation is limited. Consular processing timelines vary, so you and your employer should build at least 60 to 90 days of lead time into your start date planning to account for appointment availability and document review.
What documents does my employer need to file a TN petition for this role?
Your employer needs a detailed offer letter specifying your oncology duties, your compensation structure, and confirmation that the role requires a licensed physician. You'll need to supply your medical degree, home-country license, and any U.S. or Canadian board certification in oncology. USCIS or the CBP officer reviews whether the duties, your qualifications, and the TN physician category description all align before approving.
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