Senior AI Software Engineer Visa Sponsorship Jobs in Missouri
Missouri's senior AI software engineer market spans St. Louis and Kansas City, with employers like Mastercard, Cerner (Oracle Health), and Express Scripts actively hiring in machine learning and AI infrastructure. The state's growing fintech, healthcare technology, and defense contracting sectors drive consistent demand, and several of these employers have established visa sponsorship programs for senior-level AI engineering roles.
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Job Title
Principal Machine Learning Engineer
Job Description Summary
We are seeking a Principal ML Engineer to build and maintain artificial intelligence and machine learning systems for our business. This role combines deep technical execution with broad influence: tackling the most complex machine learning problems, designing and implementing data architectures/models, MLOps and LLMOps, and monitoring and optimization as key software, while raising the bar for engineering excellence across the Data Organization.
Reporting to the Senior Director, Data Science & AI, the Principal ML Engineer is expected to move fluidly across project/product teams — embedding in projects for days or months at a time to unblock, accelerate, and uplift delivery. They will mentor other engineers at every level, push standards for technical excellence, and help establish the ML engineering, and architectural principles that guide our work. The primary platform is Databricks and the Azure cloud ecosystem, with the expectation of evaluating and adopting additional data technologies as the platform evolves.
Role Summary
We are seeking a Principal ML Engineer to build and maintain artificial intelligence and machine learning systems for our business. This role combines deep technical execution with broad influence: tackling the most complex machine learning problems, designing and implementing data architectures/models, MLOps and LLMOps, and monitoring and optimization as key software, while raising the bar for engineering excellence across the Data Organization.
Reporting to the Senior Director, Data Science & AI, the Principal ML Engineer is expected to move fluidly across project/product teams — embedding in projects for days or months at a time to unblock, accelerate, and uplift delivery. They will mentor other engineers at every level, push standards for technical excellence, and help establish the ML engineering, and architectural principles that guide our work. The primary platform is Databricks and the Azure cloud ecosystem, with the expectation of evaluating and adopting additional data technologies as the platform evolves.
Key Responsibilities
AI/ML Model Development
- Demonstrable experience shaping the end-to-end architecture, development, and deployment of AI, including machine learning, GenAI, and Agentic models that are tailored to business use cases.
- Design and develop agentic AI systems — including multi-agent orchestration, tool-use, evaluation, and autonomous task-execution pipelines — to automate complex enterprise workflows.
- Enforce model development standards encompassing data preprocessing, feature engineering, model selection, hyperparameter tuning, evaluation, and documentation.
- Partner with data engineering teams to ensure robust, scalable, and high-quality data pipelines that support model training and inference.
AI Operations (MLOps / LLMOps)
- Implement the organization's MLOps and LLMOps capabilities, including CI/CD pipelines for data wrangling, feature engineering, model training, evaluation, deployment, and monitoring.
- Help define and enforce standards for model versioning, experiment tracking, reproducibility, and model registry management.
- Implement robust model monitoring frameworks to detect performance degradation, data drift, concept drift, and bias in production systems, with automated alerting and retraining triggers.
AI Governance
- Implement AI governance frameworks, including policies for model risk management, fairness, explainability, privacy, and security.
- Champion sound AI principles across the global business, ensuring that human oversight and accountability are embedded in every stage of the AI development lifecycle.
Essential Skills, Knowledge & Experience
- 10+ years building software or machine learning systems, including 6+ years shipping and operating machine learning in production — served, monitored, and maintained after launch.
- Prior experience as the senior-most or near-senior-most engineer on a production ML or data platform, with responsibility for architectural decisions others had to live with.
- A track record of setting technical standards that outlasted your own involvement, and of leading through influence without formal authority.
- Strong hands-on Python and SQL, and the software engineering fundamentals that keep ML systems maintainable at scale — version control, automated testing, code review, modular design — plus the discipline to enforce them across teams.
- Expert hands-on proficiency with Databricks (Spark, Lakeflow Declarative Pipelines, Delta Lake, Lakebase/Postgres, Unity Catalog, Model Serving) and the Azure data ecosystem. Deep experience on a comparable lakehouse platform will be considered, with the expectation of becoming effective on Databricks quickly.
- Experience with MLflow or an equivalent for experiment tracking, model registry, tracing, and reproducibility.
- At least one year building agentic systems that reached production use, or equivalent demonstrated work. You should be able to walk us through a system you built: how it was orchestrated, how you evaluated it, what guardrails you put around it, how it failed, and what standard you set for whoever built the next one.
- Proven ability to mentor engineers at every level and materially raise the technical standard of the teams you work with.
- Familiarity with modern machine learning frameworks and a strong instinct for reusable, scalable engineering patterns.
Preferred Skills, Knowledge & Experience
- Experience establishing an ML or AI platform capability in an organisation that did not previously have one.
- Experience embedding across multiple teams, geographies and time zones as a principal-level technical contributor.
- Familiarity with CI/CD and infrastructure-as-code tooling for data pipelines using Azure DevOps, Databricks Declarative Automation Bundles (DABs), GitHub Actions, Terraform, or equivalent.
- Good understanding of data governance, metadata management, and cataloguing in enterprise environments.
- Exposure to model serving and inference at scale — containers, REST endpoints, latency and throughput targets — or to feature stores, retrieval pipelines, or LLM cost-attribution tooling.
- Model Context Protocol (MCP) or comparable tool-integration standards.
- Commercial real estate, professional services, or another domain where the data is messy, entities are inconsistently defined, and subject matter experts are the source of truth.
LI-Remote
Cushman & Wakefield also provides eligible employees with an opportunity to enroll in a variety of benefit programs, generally including health, vision, and dental insurance, flexible spending accounts, health savings accounts, retirement savings plans, life, and disability insurance programs, and paid and unpaid time away from work. In addition to a comprehensive benefits package, Cushman and Wakefield provide eligible employees with competitive pay, which may vary depending on eligibility factors such as geographic location, date of hire, total hours worked, job type, business line, and applicability of collective bargaining agreements.
The compensation that will be offered to the successful candidate will depend on factors such as whether the position is covered by a collective bargaining agreement, the geographic area in which the work will be performed, market pay rates in that area, and the candidate’s experience and qualifications.
The company will not pay less than minimum wage for this role.
The compensation for the position is: $178,500.00 - $210,000.00
Cushman & Wakefield is an Equal Opportunity employer to all protected groups, including protected veterans and individuals with disabilities. Discrimination of any type will not be tolerated.
In compliance with the Americans with Disabilities Act Amendments Act (ADAAA), if you have a disability and would like to request an accommodation in order to apply for a position at Cushman & Wakefield, please call the ADA line at 1-888-365-5406 or email Accommodations@cushwake.com. Please refer to the job title and job location when you contact us.
Senior AI Software Engineer Job Roles in Missouri
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Search Senior AI Software Engineer Jobs in MissouriSenior AI Software Engineer Jobs in Missouri: Frequently Asked Questions
Which companies in Missouri sponsor visas for senior AI software engineers?
Mastercard's St. Louis technology hub, Oracle Health (formerly Cerner) in Kansas City, and Express Scripts have all filed H-1B visa petitions for senior AI and machine learning engineering roles. Defense contractors like Boeing and Leidos also hire senior AI engineers in Missouri, though their sponsorship practices vary by contract classification and security clearance requirements, which can affect eligibility for international candidates.
Which visa types are most common for senior AI software engineer roles in Missouri?
The H-1B is the most common visa category for senior AI software engineers in Missouri, as these roles consistently qualify as specialty occupations requiring at least a bachelor's degree in computer science, AI, or a related field. Candidates with extraordinary ability in AI research may also qualify for the O-1A. Canadians and Mexicans in qualifying engineering roles may explore the TN visa as an alternative path.
Which cities in Missouri have the most senior AI software engineer sponsorship jobs?
St. Louis and Kansas City account for the majority of senior AI software engineer sponsorship opportunities in Missouri. St. Louis draws employers in fintech, healthcare IT, and defense, while Kansas City is a hub for health technology companies following Oracle Health's major presence there. Columbia also sees some activity tied to University of Missouri research partnerships and affiliated technology spinouts.
How to find senior ai software engineer visa sponsorship jobs in Missouri?
Migrate Mate filters job listings specifically by visa sponsorship availability, making it straightforward to identify senior AI software engineer roles in Missouri where employers are actively willing to sponsor. Rather than sorting through thousands of unfiltered postings, you can search directly for Missouri-based positions in AI engineering that include sponsorship, saving significant time during a job search that may already be constrained by visa timelines.
Are there any Missouri-specific considerations for senior AI software engineers seeking visa sponsorship?
Missouri employers sponsoring H-1B workers must pay the prevailing wage for the relevant AI engineering occupation and location, which is determined by Department of Labor wage levels for the St. Louis or Kansas City metropolitan areas. Roles tied to federal defense contracts may require security clearances that are difficult or impossible to obtain without U.S. permanent residency, so it's worth confirming clearance requirements before applying to defense-sector positions.
What is the prevailing wage for sponsored senior ai software engineer jobs in Missouri?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.