Applications Analyst Jobs in South Carolina
Applications Analyst jobs in South Carolina are open across Greenville, Duncan, and Charleston and other South Carolina metros, with employers like Prisma Health, Bob Jones University, and LPL Financial hiring at every experience level. Find a role that fits below and apply directly.
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Inspire health. Serve with compassion. Be the difference.
Job Summary
Analyzes clinical, business and/or technical processes and problems to formulate and develop recommendations for new and modified systems that meet client and/or internal project requirements. Provides technical expertise in identifying, evaluating and developing systems and procedures that are cost effective and meet user requirements. Gathers and works with departments to prioritize development initiatives and activities. Provides analysis of workflow, recommends solutions, and implements application solutions to meet departmental needs. Translates departmental requests into business functional requirements. Performs financial analysis/business plan/impact assessment. Supports internal customers in such functional areas including, but not limited to, nursing, ancillary departments, Physician practices, patient accounting, medical records, finance, human resources, purchasing, sales, and contracts. Manages system upgrades and other small projects.
Essential Functions
- All team members are expected to be knowledgeable and compliant with Prisma Health's purpose: Inspire health. Serve with compassion. Be the difference.
- Creates and maintains reports to support assigned departments and functionalities from the database that is integrated into assigned supported system.
- Provides user functionality by coding programs, maintains tables and profiles, builds screens and pathways, and/or develops job run procedures to support customer requirements.
- Communicates with assigned departments and acts as the "hub" of communication between the department and Prisma Health IS. Investigates, identifies and prepares proposals to solve specific operational problems with all clinical operational areas, partnering with the department Director, Managers, and Supervisors of those departments.
- Directs the preparation and installation of applications, including workflow analysis and flowcharting, design specifications, programming and/or building, testing, training and implementation. Develops a timeline for implementation and ensures that all steps are taken to close all outstanding issues regarding the new implementation.
- Prepares test scenarios and testing schedules and organizes application integration testing. Monitors and analyzes performance during testing and communicates results to the appropriate project team members tracking and following through with issues to resolution. Accepts final responsibility for testing and debugging before final development.
- Performs the following with moderate supervision by the I/S Project Manager and/or I/S Sr. I/S Analyst; Participate in Prisma Health disaster recovery planning for assigned applications of support.
- Complete tasks on time and meet assignment dates. Accurately checks processes and tasks and ensures data integrity for assigned applications, testing to ensure new code does not impact previous version.
- Optional where appropriate: Create training materials. Incorporate various learning techniques to achieve desired outcomes. Continually assesses curriculum to ensure users are able to pick up the knowledge needed to succeed when using the systems.
- Performs other duties as assigned.
Supervisory/Management Responsibilities
- This is a non-management job that will report to a supervisor, manager, director or executive.
Minimum Requirements
- Education - Bachelor's degree in Computer Science or related field of study. Master's degree preferred.
- Experience - Two (2) years related experience in a business, computer science or clinical field/setting. Healthcare experience preferred.
In Lieu Of
- In lieu of the education and experience requirements noted above, an Associate degree in Computer Science or a related field of study and four (4) years of related Information Technology experience in a Business Computer Science, or Clinical field/setting may be considered.
- In lieu of the education and experience requirements noted above, High School Diploma or equivalent and seven (7) years related Information Technology experience in a Business, Computer Science, or Clinical field/setting may be considered.
Required Certifications, Registrations, Licenses
- CPHIMS - Preferred
Knowledge, Skills and Abilities
- SQL database knowledge preferred
- Project management software, concepts and tracking skills preferred
- Working knowledge of health care software applications preferred
- Perl/Java/XML/Linux/Apache skills preferred
- HL/7 preferred
Work Shift
Day (United States of America)
Location
Greenville Memorial Hospital
Facility
7001 Corporate
Department
70019157 ITS Identity Access Management
Share your talent with us! Our vision is simple: to transform healthcare for the benefits of the communities we serve. The transformation of healthcare requires talented individuals in every role here at Prisma Health.
See All 8 Applications Analyst Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Applications Analyst JobsApplications Analyst Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Applications Analyst Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Prisma Health3

- Bob Jones University1

- LPL Financial1

- Medical University of South Carolina1

- Röchling Automotive1

Top Industries Hiring
- Healthcare & Medical Services3
- Automotive2
- Education2
- Investment & Asset Management1
What South Carolina Employers Look For
The qualifications that appear most often in applications analyst jobs across South Carolina.
- Bachelor's degree in information technology, computer science, or a related field
- Hands-on experience supporting or configuring enterprise applications such as ERP or EMR systems
- Proficiency in SQL for querying databases and troubleshooting application data issues
- Ability to document business requirements and translate them into system configurations or change requests
- Experience with ticketing and ITSM platforms such as ServiceNow or Jira for incident tracking
- ITIL Foundation certification or demonstrated knowledge of IT service management frameworks
Applications Analyst Jobs in South Carolina: Frequently Asked Questions
How many applications analyst jobs are there in South Carolina?
There are 8+ applications analyst openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Greenville, Duncan, and Charleston. New positions post regularly as employers across South Carolina hire.
How much do applications analysts make in South Carolina?
Applications analysts in South Carolina earn a median of about $98,280 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $58,000 for the lowest 10% to over $148,660 for the top 10%. Pay rises with experience, specialty, and employer.
Which South Carolina cities have the most applications analyst jobs?
Greenville, Duncan, and Charleston have the most applications analyst openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire applications analysts in South Carolina?
Employers hiring applications analysts in South Carolina include Prisma Health, Bob Jones University, and LPL Financial, based on current listings on Migrate Mate as of June 2026.
Are there remote applications analyst jobs in South Carolina?
Yes. About 25% of applications analyst openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for applications analyst jobs in South Carolina?
You can apply to applications analyst jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 8 Applications Analyst Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Applications Analyst Jobs