Associate Director Clinical Data Management Jobs in St. Louis, MO
Associate Director Clinical Data Management jobs in St. Louis concentrate across the pharmaceutical, biotech, and healthcare sectors, with strong hiring from employers clustered in the Cortex Innovation Community, Midtown, and the broader Forest Park Southeast corridor. Employers actively posting roles right now include Mercy, BJC HealthCare, and The Cigna. See the openings below and apply to the ones that match your experience.
Find JobsOverview
Showing 5 of 67+ Associate Director Clinical Data Management jobs











Dreaming big is in our DNA. It’s who we are as a company. It’s our culture. It’s our heritage. And more than ever, it’s our future. A future where we’re always looking forward. Always serving up new ways to meet life’s moments. A future where we keep dreaming bigger. We look for people with passion, talent, and curiosity, and provide them with the teammates, resources and opportunities to unleash their full potential. The power we create together – when we combine your strengths with ours – is unstoppable. Are you ready to join a team that dreams as big as you do?
SALARY: $106,400-$126,350 , bonus and long-term incentive eligible
LOCATION: This role is based in St. Louis, Missouri, with 10–20% travel initially , increasing to approximately 40 -50 % as the program approaches go-live.
COMPANY:
We are home to the nation’s most iconic beer and beyond beer brands, including Michelob ULTRA – America’s #1 top-selling beer – as well as Busch Light, Budweiser, Bud Light, Stella Artois, Cutwater Spirits, and industry-leading craft brands. From our longstanding efforts to support American farmers, military, veterans, and first responders, to emergency drinking water donations and responsible drinking programs, we are guided by our commitment to the communities we call home and the 65,000 hardworking Americans who bring our beer to life. We are powered by a team that shares our passion to create a future with more cheers. Are you ready to join a team that dreams as big as you do?
ROLE SUMMARY:
As Senior Manager, Change Management, you will own end-to-end change management for the U.S. SAP S/4HANA transformation , Aurora . You will serve as the primary liaison between the Central Aurora Program and local U.S. Aurora Project, B usiness , and B rewery teams to ensure the workforce is ready, willing, and able to operate in the new CORE solution.
This role is accountable for driving adoption of S/4HANA through structured change management practices grounded in Prosci methodology while minimizing resistance, business disruption, and process deviation. It serves as the people and adoption integrator across Global, Zone, and Country teams.
JOB RESPONSIBILITIES:
Lead the U.S. change management strategy and plan for Aurora, applying Prosci ADKAR methodology to build awareness, desire, knowledge, ability, and reinforcement across impacted user groups.
Partner with Global Change Management, Zone PMO, and U.S. business and brewery leaders to align messaging, sequencing, and readiness across sites.
Conduct stakeholder analyses and change impact assessments to identify at-risk groups , process disruptions, and role-level impacts.
Track adoption of readiness, resistance signals, and change risks against program milestones, escalating gaps to program leadership with the PMO.
Run weekly and Sprint-based Scrum sessions with the Global Change Management and U.S. Project teams to plan, track, and optimize delivery.
Support the U.S. Project team and Zone PMO on change management-related updates for Executive governances and SteerCos .
Tools & Platforms: SAP S/4HANA & ECC, Excel , PowerPoint, Braze, Azure DevOps .
Communications & Stakeholder Engagement :
Own the C omm unications plan , partnering with U.S. Project and B usiness teams to develop and deliver targeted messaging to executives, managers, and frontline employees across each program phase via most relevant channel s .
Build and manage a sponsor and change agent network to reinforce messaging and surface frontline feedback.
Training & Enablement
Partner with Global Aurora Change Management and U.S. Project team to build a role-based training curricula, ensuring end users can operate in S/4HANA at go-live.
Map training curriculum to job profiles to ensure that the end users are assigned to the right training.
Define and track adoption and readiness metrics , including training completion, sentiment, and usage or proficiency signals , across sites and business functions.
Ambassador / Super User Program
Design a Super User / Change Ambassador program, recruiting and activating local champions to drive peer-level adoption and provide first-line support after go-live.
Execute the Ambassadors ’ journey .
Pre-Go-Live Impact Mitigation
Help Aurora Project team and business stakeholders i dentify , prioritize, and mitigate change-related business continuity risks before go-live, including workforce readiness gaps, role and process disruptions, and site-specific concerns.
Lead the planning and execution of the Impacts Mitigation workshop.
Track and manage the mitigation actions.
Hypercare & Sustainment
Lead change management support during hypercare , coordinating with Ambassadors and site leadership to resolve adoption issues and reinforce new ways of working.
Location & Travel Expectations:
During U.S. build, testing , and go-live phases, the individual should expect to travel 10–20%, increasing to approximately 40 -50 % as the program approaches go-live and cutover activities intensify.
Travel will include visits to U.S. brewery and business sites to support readiness activities, Ambassador program engagement, and go-live support.
JOB QUALIFICATIONS:
Bachelor’s degree required in Business, Information Systems, Finance, Supply Chain, Communications , or a related field.
Must be willing and able to travel across U.S. ( 40 – 5 0%) during the implementation phase.
Proven experience leading change management for ERP implementations, SAP S/4HANA programs, or large-scale enterprise transformations.
Demonstrated experience building and running Ambassador/Super User networks, training enablement programs, and stakeholder communication strategies.
Strong ability to assess organizational readiness , process changes, and translate findings into actionable mitigation plans.
Excellent communication, facilitation, and stakeholder management skills across executive, management, and frontline audiences.
Excellent project management, with a bility to manage multiple workstreams and adapt plans in a fast-paced transformation environment.
WHY ANHEUSER-BUSCH:
At Anheuser-Busch, our purpose is to create a future with more cheers. For more than 165 years as a leading American manufacturer, Anheuser-Busch has delivered a legacy of brewing great-tasting, high-quality beers that have satisfied beer drinkers for generations. As the nation’s top brewer, one of the fastest growing spirits companies, and an insurgent force in energy drinks, we drive economic prosperity nationwide through investments in our people, facilities, and communities. We are the only alcohol company that invests in the U.S. at this scale .
BENEFITS:
Health benefits including Medical, Dental, Vision, Wellness and Tax-Advantaged Savings and Spending Accounts
Life Insurance and Disability Income Protection
Generous Parental Leave and FMLA policies
401(k) Retirement Savings options with a company matching contribution
Chance to work in a fast-paced environment among a company of owners
Free Beer!
See All 67 Associate Director Clinical Data Management Jobs in St. Louis
Find roles in St. Louis that match your experience and apply in just a few clicks.
Find JobsAssociate Director Clinical Data Management Job Market in St. Louis
Who's Hiring
- Mercy3

- BJC HealthCare3

- The Cigna3

- Enterprise Mobility3

- Accenture Federal Services3

Top Industries Hiring
- Consulting & Professional Services7
- Insurance3
- Technology & Software3
- Healthcare & Medical Services3
- Education2
Associate Director Clinical Data Management Jobs in St. Louis: Frequently Asked Questions
How do I get a associate director clinical data management job in St. Louis?
The strongest path into this role in St. Louis runs through the city's pharmaceutical and contract research organization sector, where demand for clinical data leadership is most consistent. Targeting mid-size CROs and specialty pharma firms in the Cortex Innovation Community gives you the best concentration of openings. Candidates with hands-on experience in CDISC standards, EDC platform oversight, and cross-functional team leadership stand out clearly in St. Louis hiring.
Which companies hire associate director clinical data managements in St. Louis?
Employers hiring associate director clinical data managements in St. Louis right now include Mercy, BJC HealthCare, and The Cigna, based on current listings on Migrate Mate as of July 2026. The local market is anchored by established pharmaceutical companies, regional CROs, and academic medical center-affiliated research organizations that run ongoing clinical trials.
Are there remote associate director clinical data management jobs in St. Louis?
Yes, this is a desk-based, analytical leadership role that lends itself well to remote and hybrid arrangements. About 55% of associate director clinical data management openings tied to St. Louis are remote or hybrid as of July 2026, reflecting broader industry norms for data-focused director roles. Oversight of EDC systems and data governance workflows are the functions most commonly handled fully remotely by St. Louis-based employers.
How can I get a associate director clinical data management job in St. Louis with little or no experience?
The most realistic entry path in St. Louis is through a clinical data manager or senior data manager role at one of the city's CROs or pharmaceutical firms, building direct experience with trial data standards and team coordination before stepping into a director-level position. Washington University Medical Campus-affiliated research programs and regional biotech startups in the Cortex corridor regularly hire at manager levels where upward movement is well-defined. Demonstrating proficiency with SAS, Medidata Rave, or Oracle Clinical alongside a record of study closeout ownership accelerates the transition locally.
Which industries hire the most associate director clinical data managements in St. Louis?
The sectors hiring the most associate director clinical data managements in St. Louis are Consulting & Professional Services, Insurance, and Technology & Software, based on current listings on Migrate Mate as of July 2026. St. Louis's deep roots in pharmaceutical manufacturing and its growing life sciences research infrastructure, anchored by institutions in the Cortex Innovation Community, make these sectors the primary and most reliable source of local demand.
See All 67 Associate Director Clinical Data Management Jobs in St. Louis
Find roles in St. Louis that match your experience and apply in just a few clicks.
Find Jobs