Registered Nurse Med Surg Jobs in Missouri

Registered Nurse Med Surg jobs in Missouri are concentrated in large acute care hospital systems and regional medical centers, with steady demand from entry-level staff nurses through charge nurse and lead roles. Kansas City, St. Louis, and Springfield anchor the state's hiring activity, where systems like BJC HealthCare, Mercy Health, and Saint Luke's Health System maintain consistent med-surg openings. Telemetry, post-surgical recovery, and orthopedic med-surg are among the most in-demand specialties across Missouri's major facilities. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles65
Top employerMercy
Top citySt. Louis, MO
Cities hiring20
Work type100% On-site
Top industryHealthcare

Showing 5 of 65+ Registered Nurse Med Surg jobs

Centerpoint Medical Center
RN Med Surg Tele
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Centerpoint Medical Center
Added 1d ago
RN Med Surg Tele
Centerpoint Medical Center
Independence, Missouri
Customer Service
Customer Support
Hospitality & Guest Services

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Mercy
Registered Nurse, RN, FT, Nights, Med Surg
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Mercy
Added 1d ago
Registered Nurse, RN, FT, Nights, Med Surg
Mercy
St. Louis, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
Bachelor of Science
10,000+

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Centerpoint Medical Center
RN Manager Med Surg Oncology
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Centerpoint Medical Center
Added 1d ago
RN Manager Med Surg Oncology
Centerpoint Medical Center
Independence, Missouri
Healthcare Administration
Patient Services & Wellbeing
Physicians

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V
Travel RN Med Surg
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V
Added 2d ago
Travel RN Med Surg
Voyage Health
Kansas City, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
$1,763 - $1,856/yr

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BJC HealthCare
Clinical Nurse Med Surg
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BJC HealthCare
Added 2d ago
Clinical Nurse Med Surg
BJC HealthCare
O'Fallon, Missouri
Business Operations
Customer Service
Customer Success
$32 - $48.28/hr
Nursing Diploma
10,000+

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Registered Nurse Med Surg Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
13 jobs
Springfield
12 jobs
Kansas City
8 jobs
Poplar Bluff
4 jobs
Monett
3 jobs
Independence
3 jobs
Lamar
2 jobs
Fenton
2 jobs
O'Fallon
2 jobs

Registered Nurse Med Surg Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • Mercy
    Mercy15
  • CoxHealth
    CoxHealth13
  • BJC HealthCare
    BJC HealthCare6
  • SSM Health
    SSM Health4
  • Research Medical Center
    Research Medical Center4

Top Industries Hiring

  • Healthcare & Medical Services

What Missouri Employers Look For

The qualifications that appear most often in registered nurse med surg jobs across Missouri.

  • Active Missouri registered nurse license or a Nurse Licensure Compact license recognized in Missouri
  • Associate or bachelor's degree in nursing from an accredited program
  • Current BLS certification required before starting patient care
  • Minimum one year of acute care or med-surg clinical experience preferred
  • Demonstrated ability to manage a multi-patient medical-surgical unit caseload
  • ACLS certification required or expected within a defined period of hire

Registered Nurse Med Surg Jobs in Missouri: Frequently Asked Questions

How do you become a registered nurse med surg in Missouri?

You must hold an active registered nurse license issued by the Missouri State Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN. Missouri also participates in the Nurse Licensure Compact, so nurses licensed in compact states may practice without obtaining a separate Missouri license. Most med-surg positions require at least an associate degree in nursing, though many Missouri health systems prefer or require a bachelor of science in nursing.

How much do registered nurse med surgs make in Missouri?

Registered nurse med surgs in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire registered nurse med surgs in Missouri?

Missouri registered nurse med surg roles are posted by Mercy, CoxHealth, and BJC HealthCare and others right now, based on current listings on Migrate Mate as of August 2026. Missouri's largest hiring activity comes from major integrated health systems with campuses in St. Louis, Kansas City, and Springfield, where med-surg units typically carry the highest ongoing staffing needs.

Which Missouri cities have the most registered nurse med surg jobs?

St. Louis, Springfield, and Kansas City have the most registered nurse med surg openings in Missouri right now. St. Louis and Kansas City generate the largest share of postings because both metros are home to major academic medical centers and multi-hospital health systems, while Springfield's concentration of regional hospital campuses drives consistent demand in the southwest corridor of the state.

Are there remote registered nurse med surg jobs in Missouri?

Yes, but they're rare. Registered nurse med surg work is hands-on and floor-based by nature, so fully remote positions are uncommon. About 0% of registered nurse med surg openings tied to Missouri are remote or hybrid as of August 2026, and most of those involve care coordination, utilization review, or telephonic case management rather than direct patient care.

How can I get hired as a registered nurse med surg in Missouri with little or no experience?

The most realistic entry path is a nurse residency or new graduate program, which BJC HealthCare, Mercy Health, and Saint Luke's Health System all run for newly licensed RNs in Missouri. These programs place graduates directly into med-surg rotations with structured mentorship. Candidates who have completed clinical rotations in acute care settings or who hold a bachelor of science in nursing are more competitive, and obtaining ACLS certification before applying strengthens any new-grad application.

Where can I find and apply to registered nurse med surg jobs in Missouri?

You can find and apply to registered nurse med surg jobs in Missouri on Migrate Mate, which lists current openings across the state. Search the available roles, identify the ones that match your experience and preferred location, and apply directly to the positions that fit.

See All 65 Registered Nurse Med Surg Jobs in Missouri

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