Registered Nurse Med Surg Jobs in Missouri

Registered Nurse Med Surg jobs in Missouri are concentrated in large acute care hospital systems and regional medical centers, with steady demand from entry-level staff nurses through charge nurse and lead roles. Kansas City, St. Louis, and Springfield anchor the state's hiring activity, where systems like BJC HealthCare, Mercy Health, and Saint Luke's Health System maintain consistent med-surg openings. Telemetry, post-surgical recovery, and orthopedic med-surg are among the most in-demand specialties across Missouri's major facilities. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles59
Top employerMercy
Top citySt. Louis, MO
Cities hiring18
Work type100% On-site
Top industryHealthcare

Showing 5 of 59+ Registered Nurse Med Surg jobs

Registered Nurse - 4W Med Surg Cardiac - Full Time - Day Shift
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Added 3d ago
Registered Nurse - 4W Med Surg Cardiac - Full Time - Day Shift
CoxHealth
Springfield, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Bachelor's degree
10,000+

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Registered Nurse - 4W Med Surg Cardiac - Full Time - Night Shift
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Added 3d ago
Registered Nurse - 4W Med Surg Cardiac - Full Time - Night Shift
CoxHealth
Springfield, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Bachelor's degree
10,000+

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Registered Nurse, RN, Med Surg, FT, Days
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Added 6d ago
Registered Nurse, RN, Med Surg, FT, Days
Mercy
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Bachelor of Science
10,000+

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Registered Nurse- Med/ Surg
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Added 1w ago
Registered Nurse- Med/ Surg
US Department of Veterans Affairs
St. Louis, Missouri
Customer Success
Program Management
Project & Program Management
Project Management
$80k - $156k/yr
On-Site
Bachelor of Science
10,000+

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Clinical Nurse Coordinator Med Surg
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Added 1w ago
Clinical Nurse Coordinator Med Surg
Centerpoint Medical Center
Independence, Missouri
Customer Success
Program Management
Project & Program Management
Project Management

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Registered Nurse Med Surg Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
12 jobs
Springfield
11 jobs
Kansas City
5 jobs
Poplar Bluff
5 jobs
Kirksville
3 jobs
Lees Summit
3 jobs
Independence
3 jobs
Monett
2 jobs
Columbia
2 jobs

Registered Nurse Med Surg Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • Mercy13
  • CoxHealth11
  • Poplar Bluff Regional Medical Center4
  • BJC HealthCare3
  • University Health KC3

Top Industries Hiring

  • Healthcare & Medical Services

What Missouri Employers Look For

The qualifications that appear most often in registered nurse med surg jobs across Missouri.

  • Active Missouri registered nurse license or a Nurse Licensure Compact license recognized in Missouri
  • Associate or bachelor's degree in nursing from an accredited program
  • Current BLS certification required before starting patient care
  • Minimum one year of acute care or med-surg clinical experience preferred
  • Demonstrated ability to manage a multi-patient medical-surgical unit caseload
  • ACLS certification required or expected within a defined period of hire

Registered Nurse Med Surg Jobs in Missouri: Frequently Asked Questions

How do you become a registered nurse med surg in Missouri?

You must hold an active registered nurse license issued by the Missouri State Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN. Missouri also participates in the Nurse Licensure Compact, so nurses licensed in compact states may practice without obtaining a separate Missouri license. Most med-surg positions require at least an associate degree in nursing, though many Missouri health systems prefer or require a bachelor of science in nursing.

How much do registered nurse med surgs make in Missouri?

Registered nurse med surgs in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire registered nurse med surgs in Missouri?

Missouri registered nurse med surg roles are posted by Mercy, CoxHealth, and Poplar Bluff Regional Medical Center and others right now, based on current listings on Migrate Mate as of October 2026. Missouri's largest hiring activity comes from major integrated health systems with campuses in St. Louis, Kansas City, and Springfield, where med-surg units typically carry the highest ongoing staffing needs.

Which Missouri cities have the most registered nurse med surg jobs?

St. Louis, Springfield, and Kansas City have the most registered nurse med surg openings in Missouri right now. St. Louis and Kansas City generate the largest share of postings because both metros are home to major academic medical centers and multi-hospital health systems, while Springfield's concentration of regional hospital campuses drives consistent demand in the southwest corridor of the state.

Are there remote registered nurse med surg jobs in Missouri?

Yes, but they're rare. Registered nurse med surg work is hands-on and floor-based by nature, so fully remote positions are uncommon. About 0% of registered nurse med surg openings tied to Missouri are remote or hybrid as of October 2026, and most of those involve care coordination, utilization review, or telephonic case management rather than direct patient care.

How can I get hired as a registered nurse med surg in Missouri with little or no experience?

The most realistic entry path is a nurse residency or new graduate program, which BJC HealthCare, Mercy Health, and Saint Luke's Health System all run for newly licensed RNs in Missouri. These programs place graduates directly into med-surg rotations with structured mentorship. Candidates who have completed clinical rotations in acute care settings or who hold a bachelor of science in nursing are more competitive, and obtaining ACLS certification before applying strengthens any new-grad application.

Where can I find and apply to registered nurse med surg jobs in Missouri?

You can find and apply to registered nurse med surg jobs in Missouri on Migrate Mate, which lists current openings across the state. Search the available roles, identify the ones that match your experience and preferred location, and apply directly to the positions that fit.

See All 59 Registered Nurse Med Surg Jobs in Missouri

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