Associate Director Clinical Operations Jobs
Associate Director Clinical Operations jobs are open across pharmaceutical, biotechnology, medical device, and contract research organizations, from mid-level management to senior director, with specializations in oncology trials, regulatory compliance, and site management. Find a role that fits from the openings below and apply directly.
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Showing 5 of 28+ Associate Director Clinical Operations jobs
INTRODUCTION
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
THE OPPORTUNITY:
As an Associate Director, you will be responsible for the following:
- Lead and/or support development and implementation of GCP systems and inspection readiness.
- Lead and/or support the development and continuous improvement of Clinical Policies/ SOPs/ WIs/ Templates/etc. using knowledge and experience with clinical study management, International Conference on Harmonization (ICH) Guidelines, Good Clinical Practices (GCP) and regulatory requirements.
- SME for Clinical Operations GCP guidance, best industry practices, SOPs, and audit responses.
- Contribute to the development and management of business and compliance metrics to assess and continuously improve RevMed oversight and inspection readiness throughout the clinical trial lifecycle.
- Support Clinical Operations Inspection Readiness activities with clinical study teams; key participation in Mock/Regulatory Authority inspections.
- Contribute to the development and execution of Clinical Operations training programs to deliver RevMed standards, GCP, and regulatory requirements.
- Partner cross-functionally and with QA on quality initiatives, continuous improvement of GCP systems, and internal audits.
- Line management responsibilities including hiring, performance management, career development, and mentorship.
- Participate in other Clinical Operations Activities per the business need.
REQUIRED SKILLS, EXPERIENCE AND EDUCATION:
- Bachelor’s degree in biological sciences or health-related field required.
- 10+ years direct Clinical Compliance, and/or Clinical Quality Assurance experience in the pharmaceutical or biotech industry. Relevant Clinical Operations experiences may also meet the requirement.
- Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP.
- Demonstrated experience successfully developing and authoring Clinical and cross-functional SOPs ensuring compliance with GCP and regulatory requirements.
- Experience with development and monitoring of oversight activities.
- Knowledge and/or familiarity with Ex-US region(s) e.g. EMA, MHRA, PDMA.
- Ability to perform complex assessments & investigations, draw relevant conclusions, and implement appropriate solutions.
- Strong analytical, negotiation, and persuasion skills.
- Ability to deal with time demands, incomplete information, or unexpected events.
- Outstanding organizational skills with the ability to multi-task and prioritize.
- Excellent interpersonal, verbal, and written communication skills.
- Decision-making skills.
- Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
- Demonstrate proficiency in Microsoft Office Suite (Outlook, MS Word, Excel, PowerPoint); MS Project and/or Smartsheet a plus.
- Travel may be required (~25%).
PREFERRED SKILLS:
- Line Management experience.
- Oncology experience, early and/or late stage, strongly preferred.
- RN or Master’s degree in biological sciences or health-related field preferred.
- Strong working knowledge of ex-US regulations and requirements.
COMPENSATION
- Base Pay Salary Range: $186,000 - $233,000 USD
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
INTRODUCTION
Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
THE OPPORTUNITY:
As an Associate Director, you will be responsible for the following:
- Lead and/or support development and implementation of GCP systems and inspection readiness.
- Lead and/or support the development and continuous improvement of Clinical Policies/ SOPs/ WIs/ Templates/etc. using knowledge and experience with clinical study management, International Conference on Harmonization (ICH) Guidelines, Good Clinical Practices (GCP) and regulatory requirements.
- SME for Clinical Operations GCP guidance, best industry practices, SOPs, and audit responses.
- Contribute to the development and management of business and compliance metrics to assess and continuously improve RevMed oversight and inspection readiness throughout the clinical trial lifecycle.
- Support Clinical Operations Inspection Readiness activities with clinical study teams; key participation in Mock/Regulatory Authority inspections.
- Contribute to the development and execution of Clinical Operations training programs to deliver RevMed standards, GCP, and regulatory requirements.
- Partner cross-functionally and with QA on quality initiatives, continuous improvement of GCP systems, and internal audits.
- Line management responsibilities including hiring, performance management, career development, and mentorship.
- Participate in other Clinical Operations Activities per the business need.
REQUIRED SKILLS, EXPERIENCE AND EDUCATION:
- Bachelor’s degree in biological sciences or health-related field required.
- 10+ years direct Clinical Compliance, and/or Clinical Quality Assurance experience in the pharmaceutical or biotech industry. Relevant Clinical Operations experiences may also meet the requirement.
- Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP.
- Demonstrated experience successfully developing and authoring Clinical and cross-functional SOPs ensuring compliance with GCP and regulatory requirements.
- Experience with development and monitoring of oversight activities.
- Knowledge and/or familiarity with Ex-US region(s) e.g. EMA, MHRA, PDMA.
- Ability to perform complex assessments & investigations, draw relevant conclusions, and implement appropriate solutions.
- Strong analytical, negotiation, and persuasion skills.
- Ability to deal with time demands, incomplete information, or unexpected events.
- Outstanding organizational skills with the ability to multi-task and prioritize.
- Excellent interpersonal, verbal, and written communication skills.
- Decision-making skills.
- Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
- Demonstrate proficiency in Microsoft Office Suite (Outlook, MS Word, Excel, PowerPoint); MS Project and/or Smartsheet a plus.
- Travel may be required (~25%).
PREFERRED SKILLS:
- Line Management experience.
- Oncology experience, early and/or late stage, strongly preferred.
- RN or Master’s degree in biological sciences or health-related field preferred.
- Strong working knowledge of ex-US regulations and requirements.
COMPENSATION
- Base Pay Salary Range: $186,000 - $233,000 USD
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
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Find JobsAssociate Director Clinical Operations Job Market
A snapshot from current openings nationwide, updated as new roles post.
Who's Hiring
- Revolution Medicines7
- MannKind Corporation3
- Latigo Biotherapeutics2
- Sarepta Therapeutics2
Top Industries Hiring
- Biotechnology & Pharmaceuticals18
- Science & Research5
- Healthcare & Medical Services3
- Consulting & Professional Services2
- Technology & Software1
What Employers Look For
The qualifications that appear most often in associate director clinical operations jobs.
- Bachelor's or advanced degree in life sciences, nursing, or a related clinical field
- Five or more years of clinical trial management experience across multiple phases
- Deep knowledge of ICH-GCP guidelines, FDA regulations, and clinical operations SOPs
- Experience managing CROs, investigator sites, and cross-functional study teams
- Proficiency with clinical trial management systems such as Veeva Vault or Medidata Rave
- Strong budget oversight, resource planning, and risk mitigation experience across concurrent studies
Tips for Your Associate Director Clinical Operations Job Search
Quantify your trial portfolio on your resume
Hiring managers want to see the number of Phase I through IV trials you've overseen, the therapeutic areas involved, and the size of the site networks you managed. Replace vague responsibility statements with concrete scope so your experience reads at the right level.
Tailor your resume to each sponsor type
A pharma sponsor prioritizes GCP compliance and FDA submission readiness, while a CRO values throughput, client management, and multi-study oversight. Adjust which accomplishments you lead with depending on whether the employer runs its own pipeline or manages trials for clients.
Target openings by therapeutic area first
Associate director clinical operations roles in oncology, rare disease, and CNS attract narrower candidate pools than general listings, which means less competition if your background matches. Filter your search by indication before filtering by company size or location.
Apply early to roles that fit
Migrate Mate lists associate director clinical operations openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare a cross-functional leadership example for interviews
Interviewers at this level consistently ask how you've aligned clinical, regulatory, data management, and biostatistics teams under a single timeline. Have a specific trial ready where you resolved a cross-functional bottleneck, and walk through your decision-making rather than the outcome alone.
Negotiate start date and study assignment together
At the associate director level, the study you inherit on day one shapes your first year of performance reviews. When an offer is extended, it's reasonable to ask which programs you'd be assigned to and whether there's flexibility on timing if a trial is mid-enrollment.
Associate Director Clinical Operations Jobs: Frequently Asked Questions
Which companies are hiring the most associate director clinical operations?
The companies hiring the most associate director clinical operationss right now include Revolution Medicines, MannKind Corporation, and Latigo Biotherapeutics, with the largest share of openings in California, Massachusetts, and Connecticut, based on current listings on Migrate Mate as of June 2026. Activity tends to be highest at large-cap pharma companies and mid-size biotechs advancing late-stage pipelines.
How many associate director clinical operations jobs are remote?
About 25% of associate director clinical operations openings are fully remote or hybrid as of June 2026, reflecting the field's shift toward centralized monitoring and virtual oversight models. Roles focused on data review, vendor oversight, and cross-functional program management tend to offer the most location flexibility, while positions tied to site activation or on-site auditing typically require more travel.
How do you become an associate director clinical operations?
Most associate director clinical operations professionals start as clinical research associates or study coordinators, then move into clinical trial manager or senior manager roles before stepping up. Building experience across multiple therapeutic areas and trial phases, leading cross-functional teams, and demonstrating budget and vendor management skills are the steps that consistently precede promotion into this level.
Can you get an associate director clinical operations job with limited experience?
Getting hired at the associate director level with limited direct experience is difficult, but candidates who have managed complex Phase II or III trials end-to-end, led CRO relationships, or stepped into acting leadership during a vacancy can make a credible case. Targeting smaller biotechs or CROs that promote from within gives you the best chance of bridging a gap in formal title history.
What does the associate director clinical operations interview process look like?
The process typically starts with a recruiter screen focused on therapeutic area background and trial phase experience, followed by a hiring manager interview that goes deep on study oversight, cross-functional leadership, and regulatory knowledge. Later rounds often involve panel interviews with clinical, regulatory, and data management stakeholders, and some organizations ask for a written case study or presentation on a hypothetical protocol challenge.
Where can I find and apply to associate director clinical operations jobs?
You can find and apply to associate director clinical operations jobs on Migrate Mate, which lists current openings from across the United States. Find the roles that fit your therapeutic area, experience level, and work location preferences, then apply directly to each listing from the page.
See All Associate Director Clinical Operations Jobs
Jump back to the full list of openings and apply to any associate director clinical operations role that fits.
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