Senior Level Business Unit Manager Jobs
Senior level business unit manager jobs demand executives who set strategic direction, own P&L outcomes, and lead the cross-functional teams driving execution. Openings are concentrated across Manufacturing, Medical Devices, and Chemicals & Materials, with a 67% remote and hybrid mix, and employers like ITW, Sika, and Eurofins hiring at this level now.
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Senior Manager, Business Unit Systems (Hybrid)
Chicago, IL
The American Medical Association (AMA) is the nation's largest professional Association of physicians and a non-profit organization. We are a unifying voice and powerful ally for America's physicians, the patients they care for, and the promise of a healthier nation. To be part of the AMA is to be part of our Mission to promote the art and science of medicine and the betterment of public health.
At AMA, our mission to improve the health of the nation starts with our people. We foster an inclusive, people-first culture where every employee is empowered to perform at their best. Together, we advance meaningful change in health care and the communities we serve.
We encourage and support professional development for our employees, and we are dedicated to social responsibility. We invite you to learn more about us and we look forward to getting to know you.
We have an opportunity at our corporate offices in Chicago for a Senior Manager, Business Unit Systems (Hybrid) on our Publishing team. This is a hybrid position reporting into our Chicago, IL office, requiring 3 days a week in the office.
This role is responsible for managing the advertising technology ecosystem across multiple vendor and system partnerships supporting revenue, growth, and strategic initiatives for the JAMA Network journals and products. Function as a hybrid Database Manager / Engineer bridging the gap between disparate data sources and systems, both maintaining and enhancing the internal tech stack while designing and implementing integrations and solutions in support of automation. Lead and manage direct reports so that all technology works effectively within the ecosystem and operates under the principle of continuous improvement. Follow established enterprise review and approval processes for technologies and related standards, collaborating with IT, OGC, and Risk Management to ensure alignment with enterprise architecture, security, and data and AI strategy.
Responsibilities:
Advertising Systems Management 60%
- Manage the Naviga platform and related advertising technology systems including upgrades, data interchanges, revenue reporting, and APIs. Work with staff to ensure all business needs and requirements are met pertaining to business models, rate implementation, data and audience segmentation, workflows, integrations, invoicing, and reporting. Train staff when necessary.
- Ensure supported systems and vendor activities comply with AMA security policies and support a wide array of end users: Naviga System Support (end user), Naviga Data Analysis (reporting) including data delivery that feeds the AMA’s financial system.
- Support new product implementations, technology consulting engagements, and technology assessments by serving as the technical lead for vendor partnerships and projects, including aligning revenue objectives with vendor functionality and performance.
- Employ continuous improvement principles with hands-on engineering, including leveraging AI tools, to provide a sound advertising technology ecosystem that supports revenue growth and high efficiency.
- Serve as lead in the AMA IT relationship and ensure that all organizational standards are met while advancing department needs requiring enterprise support.
- Keep abreast of technical, system, and advertising industry changes, advising Director on same.
- Maintain documentation on systems and procedures.
Organizational Responsibilities 20%
- Support Director with operational recommendations and technology initiatives supporting revenue reporting, order fulfillment, sales channels, online presence, and customer success.
- Prepare technical capital and operational budgets.
- Responsible for forecasting and then managing technology costs to budget, reducing expenditure where possible.
- Support Director as needed in RFPs and negotiations, including contract reviews.
Staff Management 20%
- Lead, mentor, and provide management oversight for staff.
- Responsible for setting objectives, evaluating employee performance, and fostering a collaborative team environment.
- Responsible for developing staff knowledge and skills to support career development.
May include other responsibilities as assigned.
REQUIREMENTS
- Bachelor's degree preferred or equivalent work experience and HS diploma/equivalent education required, a Technology discipline preferred.
- 7+ years experience in revenue database administration, advertising/media order entry systems, ad technology, revenue reporting, CRM, and working with multiple vendor-supported systems.
- Experience in people management required; able to attract and develop talent.
- Strong technical knowledge particularly in revenue focused databases and ad tech.
- Knowledge of publishing environments, particularly scientific/technical/medical a plus.
- Demonstrated ability to manage cross-functional relationships with vendors and internal stakeholders.
- Demonstrated ability to evaluate systems and recommend system upgrades and workflow improvements.
- Strong verbal and written communication skills are required.
This role is an exempt position, and the salary range for this position is $119,074 - 157,855. This is the lowest to highest salary we believe we would pay for this role at the time of this posting. An employee’s pay within the salary range will be determined by a variety of factors including but not limited to business consideration and geographical location, as well as candidate qualifications, such as skills, education, and experience. Employees are also eligible to participate in an incentive plan. To learn more about the American Medical Association’s benefits offerings, please click here.
We are an equal opportunity employer, committed to diversity in our workforce. All qualified applicants will receive consideration for employment. As an EOE/AA employer, the American Medical Association will not discriminate in its employment practices due to an applicant’s race, color, religion, sex, age, national origin, sexual orientation, gender identity and veteran or disability status.
THE AMA IS COMMITTED TO IMPROVING THE HEALTH OF THE NATION
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Top Industries Hiring
- Manufacturing
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Senior Level Business Unit Manager Jobs: Frequently Asked Questions
How do I get a senior level business unit manager job?
Employers hiring at the senior level look for candidates who have owned a business unit's results end to end, not just contributed to them. Demonstrated P&L ownership, a history of building or restructuring teams, and the ability to translate company strategy into operational plans are the clearest differentiators. Candidates who can speak to measurable growth they drove, rather than projects they supported, consistently advance further in the hiring process.
Which companies hire senior level business unit managers?
Companies hiring senior level business unit managers right now include ITW, Sika, and Eurofins, based on current listings on Migrate Mate as of September 2026. Hiring at this level tends to come from large enterprises and mid-market companies undergoing growth, restructuring, or expansion into new verticals, where experienced business unit leadership is a direct operational need.
Are there remote senior level business unit manager jobs?
Yes, though many roles at this level still require regular on-site presence given the cross-functional leadership they involve. About 67% of senior level business unit manager openings are remote or hybrid as of September 2026, with hybrid arrangements being the most common format for roles that require executive visibility and team coordination across departments.
What makes a business unit manager role senior level?
Senior level business unit manager roles are defined by full ownership of a business unit's strategy, budget, and performance, rather than executing plans set by others. These positions typically involve managing managers, setting multi-year roadmaps, and representing the unit to executive leadership. The scope is broader, the accountability is higher, and candidates are expected to develop the next layer of leadership beneath them.
Which industries hire the most senior level business unit managers?
Senior Level business unit manager roles concentrate in Manufacturing, Medical Devices, and Chemicals & Materials, based on current listings on Migrate Mate as of September 2026. These sectors tend to operate with distinct, measurable business lines that require dedicated senior leadership to manage performance, allocate resources, and drive growth independently from the broader organization.