Clinical Data Management Jobs in California
Clinical Data Management jobs in California are in strong demand, concentrated in the life sciences, pharmaceutical, and biotech sectors that define the state's research economy, with openings at every level from entry-level data coordinators through senior CDM directors. San Francisco Bay Area, San Diego, and Los Angeles are the largest hiring metros, anchored by employers such as Genentech, Gilead Sciences, and AstraZeneca. The most sought-after specialties include clinical database design, CDISC/CDASH standards expertise, and regulatory-submission data management. Find a role that fits below and apply directly.
Find Clinical Data Management JobsOverview
Open roles12
Top employerRevolution Medicines
Top cityRedwood City, CA
Cities hiring7
Work type50% Remote
Top industryBiotechnology
Showing 5 of 12+ Clinical Data Management jobs
Sr. Manager, Clinical Data Management
We won't show you this job again
Added 1d ago
Shifamed LLC
Sr. Manager, Clinical Data Management
Los Gatos, California
Added 1d ago
Director of Product Management, Clinical Data & Integrations
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Added 1d ago
Prenuvo
Director of Product Management, Clinical Data & Integrations
San Francisco, California
Added 1d ago
Director, Clinical Data Management
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Added 3w ago
Bristol Myers Squibb
Director, Clinical Data Management
San Diego, California
Added 3w ago
Associate Director, Clinical Data Management
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Added 3w ago
Summit Therapeutics
Associate Director, Clinical Data Management
Palo Alto, California
Added 3w ago
Associate Director, Clinical Data Management
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Added 1mo ago
Corcept Therapeutics
Associate Director, Clinical Data Management
Redwood City, California
Added 1mo ago
Added 1d ago
Sr. Manager, Clinical Data Management
Shifamed LLC·Los Gatos, California
Job functions:
$150k - $180k/yr
Bachelor's degree
11-50 employees
Job Description
Supira Medical, a clinical-stage Shifamed Portfolio Company, is developing a low-profile, high continuous flow percutaneous ventricular assist device (pVAD) to provide temporary mechanical circulatory support in high risk percutaneous coronary interventional (HRPCI) procedures as well as patients suffering from cardiogenic shock. To learn more about Supira Medical, please visit www.supiramedical.com.
ABOUT SHIFAMED
Founded in 2009 by serial entrepreneur Amr Salahieh, Shifamed LLC is a privately held medical device innovation hub focused on the development of novel medical products to address clinical needs in the rapidly evolving fields of cardiology and ophthalmology.
Description:
The Senior Manager, Clinical Data Management sets the data management strategy for Supira Medical's cardiovascular IDE clinical trial, with particular ownership of case report form (CRF) design and the clinical systems that house patient data. This individual translates the protocol and statistical analysis plan into a data capture strategy that is fit for purpose, then partners closely, day to day, with a Data Manager to build, validate, and maintain the EDC and related clinical systems (randomization/IWRS, imaging, safety, and patient screening databases) against that strategy. The role ensures data is captured completely, accurately, and in a state that is audit-ready and submission-ready, and works cross-functionally with Biostatistics, Clinical Operations, Monitoring, Medical Safety, and Regulatory Affairs to keep the trial's data infrastructure aligned to study needs from first-patient-in through database lock.
Responsibilities, Skills & Hands-On Experience:
- CRF Design Strategy: Own the data management strategy for the trial, translating protocol and SAP requirements into a CRF design that captures the right data, at the right timepoints, in the right structure to support endpoint analysis and CEC/DSMB review.
- CRF Development & Governance: Lead CRF development and review cycles with Monitoring, Clinical Operations, and Medical Safety; drive decisions on form structure, skip logic, edit checks, and controlled terminology, and manage CRF version control and change history.
- Clinical Systems Oversight: Direct the Data Manager on day-to-day build, configuration, and maintenance of the EDC and related clinical systems (IWRS/randomization, safety database, CEC/DSMB data portals) that house patient data, ensuring systems reflect the current protocol and CRF design.
- Data Management Planning: Author and maintain the Data Management Plan (DMP), edit check specifications, data validation plan, and CRF completion guidelines; ensure documentation stays current across protocol amendments.
- Data Quality & Reconciliation: Oversee query management, data cleaning cycles, and SAE/CEC reconciliation between the clinical database and safety systems; set priorities and quality standards for the Data Manager's daily work.
- Regulatory & Data Integrity Compliance: Ensure all data management activities comply with 21 CFR Part 11, ISO 14155, and ALCOA+ data integrity principles; maintain systems and processes in an audit- and inspection-ready state.
- Vendor Management: Select and manage EDC and coding vendors (e.g., MedDRA/WHODrug); hold vendors accountable for system build timelines, validation deliverables, and ongoing support quality.
- Timeline & Milestone Management: Own the data management timeline, including database build, UAT, interim analyses, and database lock; provide status updates and risk mitigation plans to Clinical Affairs leadership.
- DSMB & CEC Data Support: Coordinate data transfers, listings, and extracts supporting DSMB reviews and CEC adjudication; partner with Biostatistics on dataset specifications and edit check logic.
- Submission Support: Collaborate with Regulatory Affairs and Biostatistics to prepare annotated CRFs (aCRFs) and data management documentation supporting IDE supplements and PMA submission.
- Team Leadership: Directly manage and mentor the Data Manager; set priorities, review deliverables, and build data management capacity as the trial scales.
Education & Work Experience:
- Bachelor's degree in life sciences, health informatics, computer science, or a related field; advanced degree a plus.
- 8+ years of clinical data management experience in the medical device or pharmaceutical/biotech industry, including direct ownership of CRF design and development.
- Hands-on experience with EDC systems (e.g., iMednet, Clario, Judi, a plus) and overseeing the clinical systems that house patient data.
- Demonstrated experience managing or mentoring a Data Manager or data management team member.
- Working knowledge of 21 CFR Part 11 and ISO 14155 as they apply to clinical data systems and data integrity.
- Experience developing Data Management Plans, edit check specifications, and data validation plans.
- Experience with query management, SAE reconciliation, and coordinating data for DSMB or CEC review.
- Strong project management and vendor management skills, with the ability to manage competing priorities across a fast-moving trial.
- Familiarity with CDISC standards (CDASH, SDTM) and preparation of annotated CRFs for regulatory submission.
- Excellent written and verbal communication skills, with the ability to translate protocol and statistical requirements into practical data capture design.
- Direct experience supporting an IDE pivotal trial for a cardiovascular, structural heart, or other Class III device, from CRF design through database lock, preferred.
- Experience with randomization/IWRS systems and integrating multiple clinical systems (EDC, safety, CEC/DSMB portals) into a single data flow, preferred.
- Experience at an early-stage or venture-backed medical device company, preferred.
- CCDM certification or equivalent.
Our salary ranges are calculated by role, level, and location. Please note that your position within that range will be determined by your job-related knowledge, location, skills, experience, relevant education, and training/certifications. The base salary range for this full-time position is between $150,000 to $180,000 + equity + benefits.
NOTICE TO CANDIDATES: Please be aware that Shifamed and its portfolio companies do not conduct interviews or extend offers through mobile web chat applications. Please report any such occurrences to hr@shifamed.com.
Shifamed LLC
Sr. Manager, Clinical Data Management
Los Gatos, California
Added 1d ago11-50 employees
Job functions:
$150k - $180k/yr
Bachelor's degree
Job Description
Supira Medical, a clinical-stage Shifamed Portfolio Company, is developing a low-profile, high continuous flow percutaneous ventricular assist device (pVAD) to provide temporary mechanical circulatory support in high risk percutaneous coronary interventional (HRPCI) procedures as well as patients suffering from cardiogenic shock. To learn more about Supira Medical, please visit www.supiramedical.com.
ABOUT SHIFAMED
Founded in 2009 by serial entrepreneur Amr Salahieh, Shifamed LLC is a privately held medical device innovation hub focused on the development of novel medical products to address clinical needs in the rapidly evolving fields of cardiology and ophthalmology.
Description:
The Senior Manager, Clinical Data Management sets the data management strategy for Supira Medical's cardiovascular IDE clinical trial, with particular ownership of case report form (CRF) design and the clinical systems that house patient data. This individual translates the protocol and statistical analysis plan into a data capture strategy that is fit for purpose, then partners closely, day to day, with a Data Manager to build, validate, and maintain the EDC and related clinical systems (randomization/IWRS, imaging, safety, and patient screening databases) against that strategy. The role ensures data is captured completely, accurately, and in a state that is audit-ready and submission-ready, and works cross-functionally with Biostatistics, Clinical Operations, Monitoring, Medical Safety, and Regulatory Affairs to keep the trial's data infrastructure aligned to study needs from first-patient-in through database lock.
Responsibilities, Skills & Hands-On Experience:
- CRF Design Strategy: Own the data management strategy for the trial, translating protocol and SAP requirements into a CRF design that captures the right data, at the right timepoints, in the right structure to support endpoint analysis and CEC/DSMB review.
- CRF Development & Governance: Lead CRF development and review cycles with Monitoring, Clinical Operations, and Medical Safety; drive decisions on form structure, skip logic, edit checks, and controlled terminology, and manage CRF version control and change history.
- Clinical Systems Oversight: Direct the Data Manager on day-to-day build, configuration, and maintenance of the EDC and related clinical systems (IWRS/randomization, safety database, CEC/DSMB data portals) that house patient data, ensuring systems reflect the current protocol and CRF design.
- Data Management Planning: Author and maintain the Data Management Plan (DMP), edit check specifications, data validation plan, and CRF completion guidelines; ensure documentation stays current across protocol amendments.
- Data Quality & Reconciliation: Oversee query management, data cleaning cycles, and SAE/CEC reconciliation between the clinical database and safety systems; set priorities and quality standards for the Data Manager's daily work.
- Regulatory & Data Integrity Compliance: Ensure all data management activities comply with 21 CFR Part 11, ISO 14155, and ALCOA+ data integrity principles; maintain systems and processes in an audit- and inspection-ready state.
- Vendor Management: Select and manage EDC and coding vendors (e.g., MedDRA/WHODrug); hold vendors accountable for system build timelines, validation deliverables, and ongoing support quality.
- Timeline & Milestone Management: Own the data management timeline, including database build, UAT, interim analyses, and database lock; provide status updates and risk mitigation plans to Clinical Affairs leadership.
- DSMB & CEC Data Support: Coordinate data transfers, listings, and extracts supporting DSMB reviews and CEC adjudication; partner with Biostatistics on dataset specifications and edit check logic.
- Submission Support: Collaborate with Regulatory Affairs and Biostatistics to prepare annotated CRFs (aCRFs) and data management documentation supporting IDE supplements and PMA submission.
- Team Leadership: Directly manage and mentor the Data Manager; set priorities, review deliverables, and build data management capacity as the trial scales.
Education & Work Experience:
- Bachelor's degree in life sciences, health informatics, computer science, or a related field; advanced degree a plus.
- 8+ years of clinical data management experience in the medical device or pharmaceutical/biotech industry, including direct ownership of CRF design and development.
- Hands-on experience with EDC systems (e.g., iMednet, Clario, Judi, a plus) and overseeing the clinical systems that house patient data.
- Demonstrated experience managing or mentoring a Data Manager or data management team member.
- Working knowledge of 21 CFR Part 11 and ISO 14155 as they apply to clinical data systems and data integrity.
- Experience developing Data Management Plans, edit check specifications, and data validation plans.
- Experience with query management, SAE reconciliation, and coordinating data for DSMB or CEC review.
- Strong project management and vendor management skills, with the ability to manage competing priorities across a fast-moving trial.
- Familiarity with CDISC standards (CDASH, SDTM) and preparation of annotated CRFs for regulatory submission.
- Excellent written and verbal communication skills, with the ability to translate protocol and statistical requirements into practical data capture design.
- Direct experience supporting an IDE pivotal trial for a cardiovascular, structural heart, or other Class III device, from CRF design through database lock, preferred.
- Experience with randomization/IWRS systems and integrating multiple clinical systems (EDC, safety, CEC/DSMB portals) into a single data flow, preferred.
- Experience at an early-stage or venture-backed medical device company, preferred.
- CCDM certification or equivalent.
Our salary ranges are calculated by role, level, and location. Please note that your position within that range will be determined by your job-related knowledge, location, skills, experience, relevant education, and training/certifications. The base salary range for this full-time position is between $150,000 to $180,000 + equity + benefits.
NOTICE TO CANDIDATES: Please be aware that Shifamed and its portfolio companies do not conduct interviews or extend offers through mobile web chat applications. Please report any such occurrences to hr@shifamed.com.
See All 12 Clinical Data Management Jobs in California
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Find Clinical Data Management JobsClinical Data Management Jobs by City in California
Where California roles are concentrated, by current openings.
Redwood City
5 jobsSan Diego
2 jobsIrvine
1 jobLos Gatos
1 jobPalo Alto
1 jobFoster City
1 jobSan Francisco
1 jobClinical Data Management Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Biotechnology & Pharmaceuticals
What California Employers Look For
The qualifications that appear most often in clinical data management jobs across California.
- Bachelor's degree in life sciences, health informatics, computer science, or a related field
- Experience with clinical data management systems such as Medidata Rave, Oracle InForm, or Veeva Vault
- Proficiency in CDISC standards including CDASH, SDTM, and ADaM for regulatory submissions
- Knowledge of FDA regulations and ICH E6 Good Clinical Practice guidelines
- Strong SQL skills and familiarity with SAS or statistical analysis tools
- Excellent attention to detail and experience writing data management plans and edit check specifications
Clinical Data Management Jobs in California: Frequently Asked Questions
How do you become a clinical data management in California?
A bachelor's degree in life sciences, health informatics, or a related field is the standard entry point for clinical data management roles in California. No state-issued license is required, but the Society for Clinical Data Management offers the Certified Clinical Data Manager credential, which California employers recognize as a professional benchmark. Most California biotech and pharma companies also look for hands-on experience with industry-standard platforms and CDISC standards before extending offers.
Which companies hire clinical data managements in California?
Employers hiring clinical data managements in California right now include Revolution Medicines, Bristol Myers Squibb, and Corcept Therapeutics, based on current listings on Migrate Mate as of August 2026. California's deep concentration of biotech, pharmaceutical, and contract research organizations means hiring activity is consistent across both large headquarters and mid-size clinical-stage companies throughout the Bay Area and San Diego.
Which California cities have the most clinical data management jobs?
Redwood City, San Diego, and Irvine are the California cities with the most clinical data management openings. The San Francisco Bay Area leads because it is home to major pharmaceutical and biotech headquarters, while San Diego's strong cluster of clinical-stage biotech firms and contract research organizations drives steady demand, and Los Angeles draws volume from a growing number of life sciences campuses and hospital-affiliated research programs.
Are there remote clinical data management jobs in California?
Yes, and more than most clinical roles, since clinical data management work is primarily desk-based and does not require on-site patient contact. About 50% of clinical data management openings tied to California are remote or hybrid as of August 2026, reflecting how well the work translates to distributed teams. Database builds, edit check programming, and data review activities are the functions most commonly performed fully remotely.
How can I get hired as a clinical data management in California with little or no experience?
The most realistic entry path is a junior or associate clinical data coordinator role, which large California contract research organizations and mid-size biotech companies post regularly for candidates coming directly from life sciences or health informatics degree programs. Companies such as ICON and Labcorp Drug Development run associate-level CDM programs that accept new graduates. Building proficiency in Medidata Rave or a comparable platform through a certificate course and earning the SCDM's entry-level credential strengthens a California application considerably even without commercial experience.
Where can I find and apply to clinical data management jobs in California?
You can find and apply to clinical data management jobs in California on Migrate Mate, which lists current California openings updated regularly. Search the listings, find roles that match your background and preferred location, and apply directly to the ones that fit.
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