Clinical Investigator Jobs
Clinical Investigator jobs are open across pharmaceutical, biotechnology, medical device, and academic research sectors, from entry-level research associate to principal and lead investigator, with common specializations in oncology trials, Phase I-III clinical studies, and regulatory compliance. Scan the live roles below and apply to whichever ones fit.
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JClinical Research Sub-Investigator (APRN/PA) – 1099 Contract
At Be Well Clinical Studies, we are committed to advancing clinical research while expanding access to innovative treatment options for the communities we serve. We are seeking an experienced Advanced Practice Registered Nurse (APRN/NP) or Physician Assistant (PA) to join our Omaha clinical research team as a 1099 Contract Sub-Investigator (Sub-I).
This is a part-time, flexible contracted position, with hours based on active study needs and scheduled participant visits. Compensation ranges from $55–$75 per hour, based on experience, credentials, and clinical research background.
About the Role
As a Sub-Investigator, you will work under the supervision of the Principal Investigator (PI) and perform delegated clinical and protocol-related responsibilities within your professional scope of practice. You will play an important role in protecting participant safety, evaluating study eligibility, completing protocol-required medical assessments, and supporting the compliant execution of clinical trials.
You will collaborate closely with Principal Investigators, study coordinators, and other members of the clinical research team to ensure studies are conducted in accordance with approved protocols, Good Clinical Practice (GCP), applicable regulatory requirements, and Be Well Clinical Studies policies and procedures.
Key Responsibilities
- Clinical Assessments & Participant Safety: Conduct protocol-required physical examinations, medical assessments, and other delegated clinical procedures within scope of practice.
- Participant Eligibility: Review medical history, medications, laboratory results, and other clinical information to evaluate study eligibility according to protocol inclusion and exclusion criteria.
- Safety Oversight: Evaluate participant health concerns and potential adverse events, provide appropriate clinical assessment, and ensure timely documentation and escalation to the Principal Investigator when required.
- Study Visit Support: Provide medical coverage for protocol-required visits and procedures, which may include study-specific assessments, infusions, vaccinations, or other medically attended procedures.
- Participant Communication: Address participant questions related to study procedures, investigational products, medications, and health concerns within the scope of the Sub-Investigator role.
- Protocol & Regulatory Compliance: Perform delegated study responsibilities in accordance with study protocols, Good Clinical Practice (GCP), applicable regulatory requirements, IRB requirements, and sponsor expectations.
- Clinical Documentation: Complete study-related clinical documentation accurately, thoroughly, and within required timelines.
- Training & Study Readiness: Maintain required professional licensure, GCP certification, and study-specific training throughout participation in assigned clinical trials.
- Team Collaboration: Work closely with the Principal Investigator and clinical research team to support participant safety, protocol compliance, study quality, and successful trial execution.
Why Join Be Well Clinical Studies?
- Flexible contract opportunity that can complement an existing clinical practice or other professional commitments.
- Opportunity to gain or expand hands-on clinical research experience across a variety of therapeutic areas.
- Work alongside experienced investigators and a dedicated clinical research operations team.
- Contribute directly to expanding access to clinical research opportunities for patients in the Omaha community.
- Flexible scheduling based primarily on active studies and participant visit needs.
Required Qualifications
- Current, unrestricted license to practice as an Advanced Practice Registered Nurse/Nurse Practitioner (APRN/NP) or Physician Assistant (PA) in Nebraska.
- Graduate degree from an accredited Nurse Practitioner, Advanced Practice Nursing, or Physician Assistant program.
- Current national board certification appropriate to professional discipline.
- Current BLS certification.
- Strong clinical assessment skills and ability to perform physical examinations, review medical histories and medications, assess laboratory and other clinical information, and exercise appropriate clinical judgment within scope of practice.
- Strong attention to detail and ability to accurately document clinical assessments and study-related activities.
- Ability to work collaboratively with Principal Investigators, research staff, sponsors, monitors, and other clinical professionals.
- Ability to complete and maintain Good Clinical Practice (GCP) certification and required study-specific training.
- Ability to maintain participant confidentiality and adhere to applicable regulatory, ethical, and institutional requirements.
- Availability to provide flexible clinical coverage based on scheduled study visits and participant needs.
Preferred Qualifications
- Previous clinical research or clinical trial experience.
- Previous experience serving as a Sub-Investigator or working within an investigator site.
- Familiarity with FDA-regulated clinical trials, Good Clinical Practice (GCP), IRB requirements, and clinical research documentation.
- Experience evaluating medical histories, medications, laboratory results, and adverse events within a clinical setting.
- Experience working independently in an advanced practice clinical role.
Clinical research experience is preferred but not required. APRNs and PAs who are new to clinical research but demonstrate strong clinical judgment, attention to detail, and an interest in clinical trials are encouraged to apply.
Pay: $55.00 - $75.00 per hour
Expected hours: 4.0 – 16.0 per week
Work Location: In person
JClinical Research Sub-Investigator (APRN/PA) – 1099 Contract
At Be Well Clinical Studies, we are committed to advancing clinical research while expanding access to innovative treatment options for the communities we serve. We are seeking an experienced Advanced Practice Registered Nurse (APRN/NP) or Physician Assistant (PA) to join our Omaha clinical research team as a 1099 Contract Sub-Investigator (Sub-I).
This is a part-time, flexible contracted position, with hours based on active study needs and scheduled participant visits. Compensation ranges from $55–$75 per hour, based on experience, credentials, and clinical research background.
About the Role
As a Sub-Investigator, you will work under the supervision of the Principal Investigator (PI) and perform delegated clinical and protocol-related responsibilities within your professional scope of practice. You will play an important role in protecting participant safety, evaluating study eligibility, completing protocol-required medical assessments, and supporting the compliant execution of clinical trials.
You will collaborate closely with Principal Investigators, study coordinators, and other members of the clinical research team to ensure studies are conducted in accordance with approved protocols, Good Clinical Practice (GCP), applicable regulatory requirements, and Be Well Clinical Studies policies and procedures.
Key Responsibilities
- Clinical Assessments & Participant Safety: Conduct protocol-required physical examinations, medical assessments, and other delegated clinical procedures within scope of practice.
- Participant Eligibility: Review medical history, medications, laboratory results, and other clinical information to evaluate study eligibility according to protocol inclusion and exclusion criteria.
- Safety Oversight: Evaluate participant health concerns and potential adverse events, provide appropriate clinical assessment, and ensure timely documentation and escalation to the Principal Investigator when required.
- Study Visit Support: Provide medical coverage for protocol-required visits and procedures, which may include study-specific assessments, infusions, vaccinations, or other medically attended procedures.
- Participant Communication: Address participant questions related to study procedures, investigational products, medications, and health concerns within the scope of the Sub-Investigator role.
- Protocol & Regulatory Compliance: Perform delegated study responsibilities in accordance with study protocols, Good Clinical Practice (GCP), applicable regulatory requirements, IRB requirements, and sponsor expectations.
- Clinical Documentation: Complete study-related clinical documentation accurately, thoroughly, and within required timelines.
- Training & Study Readiness: Maintain required professional licensure, GCP certification, and study-specific training throughout participation in assigned clinical trials.
- Team Collaboration: Work closely with the Principal Investigator and clinical research team to support participant safety, protocol compliance, study quality, and successful trial execution.
Why Join Be Well Clinical Studies?
- Flexible contract opportunity that can complement an existing clinical practice or other professional commitments.
- Opportunity to gain or expand hands-on clinical research experience across a variety of therapeutic areas.
- Work alongside experienced investigators and a dedicated clinical research operations team.
- Contribute directly to expanding access to clinical research opportunities for patients in the Omaha community.
- Flexible scheduling based primarily on active studies and participant visit needs.
Required Qualifications
- Current, unrestricted license to practice as an Advanced Practice Registered Nurse/Nurse Practitioner (APRN/NP) or Physician Assistant (PA) in Nebraska.
- Graduate degree from an accredited Nurse Practitioner, Advanced Practice Nursing, or Physician Assistant program.
- Current national board certification appropriate to professional discipline.
- Current BLS certification.
- Strong clinical assessment skills and ability to perform physical examinations, review medical histories and medications, assess laboratory and other clinical information, and exercise appropriate clinical judgment within scope of practice.
- Strong attention to detail and ability to accurately document clinical assessments and study-related activities.
- Ability to work collaboratively with Principal Investigators, research staff, sponsors, monitors, and other clinical professionals.
- Ability to complete and maintain Good Clinical Practice (GCP) certification and required study-specific training.
- Ability to maintain participant confidentiality and adhere to applicable regulatory, ethical, and institutional requirements.
- Availability to provide flexible clinical coverage based on scheduled study visits and participant needs.
Preferred Qualifications
- Previous clinical research or clinical trial experience.
- Previous experience serving as a Sub-Investigator or working within an investigator site.
- Familiarity with FDA-regulated clinical trials, Good Clinical Practice (GCP), IRB requirements, and clinical research documentation.
- Experience evaluating medical histories, medications, laboratory results, and adverse events within a clinical setting.
- Experience working independently in an advanced practice clinical role.
Clinical research experience is preferred but not required. APRNs and PAs who are new to clinical research but demonstrate strong clinical judgment, attention to detail, and an interest in clinical trials are encouraged to apply.
Pay: $55.00 - $75.00 per hour
Expected hours: 4.0 – 16.0 per week
Work Location: In person
Clinical Investigator Jobs by Experience Level
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Find Clinical Investigator JobsClinical Investigator Job Market
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Education
- Biotechnology & Pharmaceuticals
What Employers Look For
The qualifications that appear most often in clinical investigator jobs.
- MD, DO, or PhD in a relevant biomedical or clinical science field
- Experience conducting or overseeing Phase I through Phase III clinical trials
- GCP certification and familiarity with ICH E6 guidelines and FDA regulations
- Proficiency with clinical trial management systems and electronic data capture platforms
- Experience with protocol development, IRB submissions, and informed consent processes
- Strong publication record or demonstrated ability to contribute to scientific manuscripts
Tips for Your Clinical Investigator Job Search
Tailor your resume to trial phases
Hiring managers for clinical investigator roles want to see which trial phases you've worked on. Separate your experience by Phase I, II, and III, and name the therapeutic areas, protocol types, and GCP standards you applied in each.
List your protocol and regulatory experience specifically
Generic phrases like 'regulatory knowledge' won't get you past screening. Name the specific submissions you've prepared, IRB correspondence you've handled, and whether you've worked under FDA 21 CFR Part 11 or ICH E6 guidelines.
Apply early to roles that fit
Migrate Mate lists clinical investigator openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Filter openings by therapeutic area and sponsor type
A role at a contract research organization demands different site management experience than one at a biopharma sponsor. Knowing which side you're targeting helps you filter faster and write a cover letter that speaks to exactly what that employer values.
Prepare for protocol-based case study questions
Many clinical investigator interviews include scenario questions about protocol deviations, adverse event reporting timelines, or enrollment challenges. Walk through a real situation you managed, name the protocol, and explain the corrective action you took.
Negotiate your research budget authority upfront
Salary isn't the only negotiable. Ask early about discretionary budget for lab supplies, CRO vendor selection authority, and conference travel. These terms are easier to set at the offer stage than to revisit six months into the role.
Clinical Investigator Jobs: Frequently Asked Questions
Which companies are hiring the most clinical investigators?
The most active employers for clinical investigators right now are The IMA, Hawthorne Health, and HonorHealth, and the most openings are in Texas, Florida, and New Jersey, based on current listings on Migrate Mate as of November 2026. Demand is typically strongest at large biopharma sponsors and contract research organizations running multi-site studies.
How many clinical investigator jobs are remote?
About 52% of clinical investigator openings are fully remote or hybrid as of November 2026, though the share varies sharply by function. Data review, protocol writing, and regulatory affairs work is more remote-eligible, while site-based roles overseeing patient enrollment and adverse event monitoring almost always require on-site presence.
How do you become a clinical investigator?
Start by earning an advanced degree in medicine, pharmacy, or a biomedical science, then gain hands-on research experience through residency, fellowship, or a research coordinator role. Complete GCP training, build familiarity with IRB submission processes, and pursue early authorship opportunities to establish a publication record that supports independent investigator applications.
Can you get hired as a clinical investigator with little experience?
Entry-level clinical investigator roles do exist, particularly at contract research organizations and academic medical centers. Hiring managers for these positions prioritize GCP certification, demonstrated experience managing patient-facing research as a coordinator or sub-investigator, and at least one co-authored publication or poster presentation over years of independent trial leadership.
What does the clinical investigator interview process look like?
Most processes run three to four rounds. An initial call screens for GCP knowledge and trial phase experience, followed by a technical interview covering protocol interpretation and regulatory decision-making. Later rounds often include a case study or presentation on a past study you led. Final interviews typically involve department leadership and may include a discussion of your proposed research agenda.
Where can I find and apply to clinical investigator jobs?
You can find and apply to clinical investigator jobs on Migrate Mate, which lists current openings from across the United States. Search the available roles to find positions that match your therapeutic area, trial phase experience, and location preferences, then apply directly to each listing that fits.
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