Clinical Research Associate Jobs in Boston, MA
Clinical Research Associate jobs in Boston are in strong demand, concentrated in the Longwood Medical Area, Kendall Square, and the Seaport District across biopharma, medical device, and academic medical center research. Employers hiring right now include Zoox, PwC, and Whoop. Find a role that fits below and apply directly.
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We help organizations move AI out of experimentation and into production — safely, reliably, and at scale. From inconsistent performance to limited transparency and challenges with integration and long-term viability, our Applied Intelligence Engine solves the risks that cause most AI initiatives to stall.
Built for some of the most highly regulated industries in the world, we enable teams to deploy AI systems that are auditable, explainable, and aligned with real-world constraints. Our solutions introduce structure, visibility, and control into how AI operates, turning advanced capabilities into a dependable, production-grade infrastructure so our customers can move faster and scale with confidence.
Job Overview
You’ll help build Clearwing: an AI-native cybersecurity system for autonomous vulnerability discovery, exploit validation, pen-testing, reverse engineering, and security reporting. You’ll combine hands-on offensive security work with LLM agent development, eval design, and product engineering. The ideal candidate can chase real bugs, validate exploitability, write production-quality Python, and turn exploratory research into repeatable security capabilities.
Responsibilities
- Develop AI-assisted vulnerability discovery workflows for source code, binaries, networks, and live systems.
- Build and improve Clearwing’s source-code hunting, network pen-testing, N-day exploit, reverse engineering, and validation pipelines.
- Design agentic workflows for reconnaissance, static analysis, dynamic testing, exploit development, patch validation, and reporting.
- Perform static analysis to identify vulnerable patterns, reachable attack surfaces, and exploitability conditions.
- Conduct authorized live testing against networks, services, containers, lab targets, and operational environments.
- Develop and validate proof-of-concept exploits in controlled, authorized settings.
- Build evaluation harnesses for vulnerability discovery quality, false positives, exploitability, reproducibility, and model/tool performance.
- Improve safety, authorization, auditability, guardrails, and human-in-the-loop controls for dual-use cybersecurity capabilities.
- Work with AI researchers and engineers to improve prompts, tools, agent loops, memory systems, scoring systems, and model-routing strategies.
- Produce clear technical reports with evidence, reproduction steps, impact analysis, and remediation guidance.
Requirements
- 3+ years of hands-on cybersecurity experience in vulnerability research, penetration testing, exploit development, reverse engineering, or security engineering.
- Practical experience with at least two of:
- Static analysis
- Dynamic analysis
- Binary exploitation
- Web application security
- Network penetration testing
- Cloud/container security
- Malware analysis or reverse engineering
- Detection engineering
- Strong Python skills and comfort building automation around security tools
- Familiarity with Linux, Docker, Kali/security tooling, Git, CI, and shell workflows
- Ability to reason from vulnerability signal to exploitability, impact, evidence quality, and remediation
- Experience working with LLMs, agents, prompt engineering, evals, or AI-assisted security workflows
- Strong written communication skills for technical findings, customer-facing reports, and internal research notes
- Clear judgment around authorization, responsible disclosure, and dual-use security tooling
Nice-to-haves
- Experience with Ghidra, IDA, Binary Ninja, angr, Semgrep, CodeQL, Joern, AFL++, libFuzzer, ASan/UBSan, or OSS-Fuzz
- Experience developing exploits for memory corruption, deserialization, auth bypass, SSRF, RCE, sandbox escape, or supply-chain vulnerabilities
- Experience with CVE reproduction, N-day analysis, patch diffing, or exploit validation
- Experience building LLM agents, tool-using systems, ReAct loops, eval harnesses, or synthetic-data pipelines
- Familiarity with SARIF, CVSS, CWE, MITRE ATT&CK, MITRE CVE workflows, HackerOne/Bugcrowd-style disclosure, or government security reporting
- Experience with Rust, Go, C/C++, or systems programming
- Prior work with security products, autonomous agents, fuzzing infrastructure, or government/security customers
Benefits
- Comprehensive benefits package, including health, dental, and vision insurance, as well as retirement savings plans
- Opportunities for growth and professional development
- A collaborative and supportive company culture that values diversity and inclusion
- Access to cutting-edge technology and resources for research and development
- Compensation (commensurate with experience): $180,000 - $200,000 (base salary) + equity
Preferred Locations: AZ, CA, CO, CT, DC, FL, KS, ME, MD, MA, MN, NV, NH, NJ, NM, NY, PA, SC, TX, VA, WA
Lazarus AI is an equal opportunity employer. We are committed to equal employment opportunity and nondiscrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. We do not tolerate discrimination or harassment of any kind. This applies to every aspect of employment at Lazarus, including, but not limited to, employment, training, promotion, demotion, transfer, leaves of absence and termination.
See All 59 Clinical Research Associate Jobs in Boston
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Find JobsClinical Research Associate Job Market in Boston
Who's Hiring
- Zoox7

- PwC3

- Whoop3

- Medpace3

- Tempus AI2

Top Industries Hiring
- Technology & Software13
- Automotive7
- Science & Research7
- Healthcare & Medical Services7
- Insurance5
Clinical Research Associate Jobs in Boston: Frequently Asked Questions
How do I get a clinical research associate job in Boston?
Focus your search on the Longwood Medical Area, Kendall Square, and the Seaport District, where biopharma sponsors, contract research organizations, and academic medical centers concentrate their clinical operations teams. Candidates with GCP certification, therapeutic area experience in oncology or rare disease, and hands-on trial coordination background stand out in Boston's competitive market. Targeting CROs and mid-size biotech firms is often the fastest path to a first CRA role here.
Which companies hire clinical research associates in Boston?
Companies currently hiring clinical research associates in Boston include Zoox, PwC, and Whoop, per current listings on Migrate Mate as of June 2026. Boston's hiring mix skews toward biopharma sponsors, global CROs with regional hubs, and large academic health systems running investigator-initiated and industry-sponsored trials.
Are there remote clinical research associate jobs in Boston?
Yes, though field-based monitoring roles require regular on-site visits to clinical sites and are rarely fully remote. About 45% of clinical research associate openings tied to Boston are remote or hybrid as of June 2026, reflecting a broader industry shift post-pandemic. Sponsor-side data management, regulatory affairs support, and study coordination roles tend to offer the most remote flexibility among Boston-area CRA positions.
How can I get a clinical research associate job in Boston with little or no experience?
The most realistic entry path in Boston is through a clinical research coordinator role at one of the city's major academic medical centers, such as those in the Longwood Medical Area or affiliated with Boston-area teaching hospitals, which regularly hire coordinators without prior CRA experience. CROs headquartered or staffed in Kendall Square also hire associate CRAs for entry-level monitoring work. GCP training and a life sciences degree give candidates a concrete edge when applying to these roles.
Which industries hire the most clinical research associates in Boston?
The sectors hiring the most clinical research associates in Boston are Technology & Software, Automotive, and Science & Research, based on current listings on Migrate Mate as of June 2026. Boston's deep cluster of biopharma headquarters, CRO regional offices, and world-renowned academic medical centers makes it one of the highest-density clinical trial markets in the country, sustaining consistent demand across all three sectors.
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