Senior Level Clinical Research Associate Jobs
Senior level clinical research associate jobs put experienced professionals in charge of study direction, site oversight, and the quality outcomes that trials depend on. Roles are concentrated across Education, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, with a mix of on-site, remote, and hybrid positions available and employers like Jobot, Colgate-Palmolive, and Cambridge Pharma Consulting hiring at this level now.
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The University of Alabama at Birmingham (UAB), Family & Community Medicine Chair Office, is seeking a Manager-Clinical Research Administration.
The Clinical Research Administration Manager will play a pivotal role in overseeing all aspects of clinical trial operations within the Department of Family and Community Medicine at UAB. This position is responsible for managing a team of clinical coordinators, ensuring compliance with regulatory requirements, and fostering collaboration with internal and external research sites. The ideal candidate will demonstrate strong leadership, organizational, and communication skills, with a proven track record in clinical research management.
General Responsibilities
To act as a subject matter expert (SME) for faculty and staff regarding administrative duties for industry and sponsored clinical research.
To serve as a referral resource for the clinical research community at UAB.
To manage and maintain the study s compliance with institutional requirements.
To manage division-wide training in ethical conduct of research.
To manage, assess and determine solutions for operational shortcomings of protocols.
To provide human resources oversight for subordinate personnel.
Key Duties & Responsibilities
Manages and supervises clinical research coordinators and research staff, including all applicable human resource functions, across multiple ongoing and upcoming clinical trials.
Prepares, submits, and maintains regulatory documentation, including IRB submissions, amendments, and continuing reviews, while supporting broader regulatory compliance activities as needed.
Leads and coordinates study activation, site initiation, ongoing management, and study closeout activities across multiple clinical research protocols.
Monitors study progress and staff activities to ensure adherence to study protocols, timelines, budgets, and all clinical and regulatory requirements.
Develops protocol-specific systems and study documentation, including process flows, training materials, CRFs, and other operational tools.
Prepares and manages study budgets, and collaborates with investigators and sponsors on financial planning and execution.
Provides training, mentorship, and professional development for research staff, including assigning responsibilities, reviewing work, and identifying process improvements.
Coordinates communication with internal teams, investigators, sponsors, and external research sites to ensure efficient trial operations and data integrity.
Develops and implements recruitment and retention strategies to support successful study enrollment and completion.
Ensures compliance with all applicable federal, state, and institutional regulations and guidelines (e.g., FDA, IRB, GCP).
Collaborates with investigators, sponsors, and other stakeholders to support successful trial execution.
Performs other duties as assigned.
Annual Salary Range: $77,640 - $126,170
Bachelor's degree in a related field and eight (8) years of related experience required. Work experience may NOT substitute for education requirement. Certified Clinical Research Coordinator (CCRC) or Certified Clinical Research Professional (CCRP) certification strongly preferred.
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
The University of Alabama at Birmingham (UAB), Family & Community Medicine Chair Office, is seeking a Manager-Clinical Research Administration.
The Clinical Research Administration Manager will play a pivotal role in overseeing all aspects of clinical trial operations within the Department of Family and Community Medicine at UAB. This position is responsible for managing a team of clinical coordinators, ensuring compliance with regulatory requirements, and fostering collaboration with internal and external research sites. The ideal candidate will demonstrate strong leadership, organizational, and communication skills, with a proven track record in clinical research management.
General Responsibilities
To act as a subject matter expert (SME) for faculty and staff regarding administrative duties for industry and sponsored clinical research.
To serve as a referral resource for the clinical research community at UAB.
To manage and maintain the study s compliance with institutional requirements.
To manage division-wide training in ethical conduct of research.
To manage, assess and determine solutions for operational shortcomings of protocols.
To provide human resources oversight for subordinate personnel.
Key Duties & Responsibilities
Manages and supervises clinical research coordinators and research staff, including all applicable human resource functions, across multiple ongoing and upcoming clinical trials.
Prepares, submits, and maintains regulatory documentation, including IRB submissions, amendments, and continuing reviews, while supporting broader regulatory compliance activities as needed.
Leads and coordinates study activation, site initiation, ongoing management, and study closeout activities across multiple clinical research protocols.
Monitors study progress and staff activities to ensure adherence to study protocols, timelines, budgets, and all clinical and regulatory requirements.
Develops protocol-specific systems and study documentation, including process flows, training materials, CRFs, and other operational tools.
Prepares and manages study budgets, and collaborates with investigators and sponsors on financial planning and execution.
Provides training, mentorship, and professional development for research staff, including assigning responsibilities, reviewing work, and identifying process improvements.
Coordinates communication with internal teams, investigators, sponsors, and external research sites to ensure efficient trial operations and data integrity.
Develops and implements recruitment and retention strategies to support successful study enrollment and completion.
Ensures compliance with all applicable federal, state, and institutional regulations and guidelines (e.g., FDA, IRB, GCP).
Collaborates with investigators, sponsors, and other stakeholders to support successful trial execution.
Performs other duties as assigned.
Annual Salary Range: $77,640 - $126,170
Bachelor's degree in a related field and eight (8) years of related experience required. Work experience may NOT substitute for education requirement. Certified Clinical Research Coordinator (CCRC) or Certified Clinical Research Professional (CCRP) certification strongly preferred.
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
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Senior Level Clinical Research Associate Jobs: Frequently Asked Questions
How do I get a senior level clinical research associate job?
Employers at this level look for candidates who have led multi-site trials, managed protocol deviations independently, and mentored junior monitors. Demonstrating ownership of inspection-readiness activities, regulatory submission support, and cross-functional vendor relationships gives candidates a clear edge. Therapeutic area depth, particularly in oncology, rare disease, or medical devices, and a history of audit-ready site portfolios tend to separate finalists from the broader applicant pool.
Which companies hire senior level clinical research associates?
Companies hiring senior level clinical research associates right now include Jobot, Colgate-Palmolive, and Cambridge Pharma Consulting, based on current listings on Migrate Mate as of August 2026. Hiring at this level comes primarily from large contract research organizations, biopharma sponsors, and medical device manufacturers running complex, multi-country trials that require experienced monitors who can work with minimal oversight.
Are there remote senior level clinical research associate jobs?
Yes, though most remote roles still require periodic site travel for monitoring visits and close-out activities. About 42% of senior level clinical research associate openings are remote or hybrid as of August 2026, reflecting how sponsors and CROs have restructured oversight models since the expansion of risk-based monitoring approaches across the industry.
What makes a clinical research associate role senior level?
Senior level clinical research associate roles are defined by independent ownership of complex or high-risk site portfolios, responsibility for mentoring and reviewing the work of junior monitors, and direct involvement in protocol development feedback, regulatory inspections, and escalation decisions. Candidates are expected to resolve issues without escalating routine problems and to serve as a subject matter resource for their therapeutic area rather than following a defined playbook.
Which industries hire the most senior level clinical research associates?
Senior Level clinical research associate roles concentrate in Education, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of August 2026. These sectors drive hiring because they run the largest volumes of regulated clinical trials, carry the greatest compliance risk, and rely on experienced monitors to maintain data integrity and inspection readiness across geographically distributed study sites.