Senior Software Engineering Jobs at Amgen with Visa Sponsorship
Senior Software Engineering jobs at Amgen involve building and scaling platforms across clinical data, bioinformatics, and drug development pipelines. The company has a consistent record of sponsoring work visas for this function, supporting candidates from initial offer through long-term status.
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Engineering
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
SENIOR ENGINEER - DRUG SUBSTANCE PROCESS ENGINEERING
What you will do
Let’s do this. Let’s change the world. In this vital role you will be responsible for planning, design, construction, operations and maintenance technical support of Amgen manufacturing infrastructure, worldwide. The Engineering Technical Authority (ETA) is responsible for technical direction, leadership, guidance and support for a specific array of process systems within an area of responsibility, such as Upstream Processes, Downstream Processes, Fill/Finish, CIP/SIP, Utilities, HVAC, Packaging, Devices, etc. Through their team(s) of global and site technical subject matter experts, the ETA will leverage engineering expertise both in the company and industry to optimize the life cycle management of Amgen’s assets and is accountable for performance and reliability across multiple sites.
This position is in the Drug Substance Process Systems Engineering team with an initial emphasis on capital project support for the DS facility at Amgen-North Carolina (ANC). Subsequent responsibilities will include end-to-end engineering support for future projects and technical global network management.
The successful candidate’s role will include responsibilities as a process equipment engineering lead delivering on design, construction & commissioning for ANC. This individual will be responsible for the successful design, integration, commissioning & qualification of a subset of process equipment on the ANC1 Expansion project. They will work with key partners to coordinate the successful delivery of qualified equipment to the site.
- Planning: Working with clients, as appropriate (e.g. PD, Quality, Manufacturing), develop and specify engineering standards, specifications, equipment selection and design. Develop metrics to support procurement strategies for equipment, inventory management, spares and preventative maintenance. Manage and track changes to specifications and standards, and system configuration.
- Design: Ensure adherence to standards and good engineering practices. Lead design of new systems in support of projects and new technology deployment. Ensure designs optimize the total life cycle of the asset, from both a cost and effectiveness standpoint.
- Construction: Use their ETA network to provide engineering support during the construction process, including responses to RFIs, resolving complex technical issues and conflicts, supporting overall project objectives.
- Commissioning: Ensure commissioning and qualification standards are developed and used. Use their network to provide engineering support to commissioning and qualification.
- Operations: Support development of, or approve operation procedures for the safe, efficient and effective operations of systems. Review performance data and make recommendations for improvement of system operations. Support NC/CAPA investigations related to equipment failures.
- Maintenance: Support systems failure analysis, approve maintenance standards and techniques. Support and review reliability and failure data, and implement actions to improve effectiveness, and reliability of systems. Assist the sites in system troubleshooting and take action as necessary to prevent future occurrence throughout network.
- Management: Lead their technical network. Makes use of expertise at the site and corporate levels for solving problems and deploying solutions across all sites. Identify and resolve issues and conflicts. Provide mentoring of other members in their network. Ensure technical decisions for assigned systems are optimized with those managed by other ETAs. Remain current on state-of-the-art for systems for adoption of new techniques and technology within Amgen. Represent Amgen with outside firms, technical societies and regulatory bodies.
This role involves travel up to 30% including overnight stays.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a person with these qualifications.
Basic Qualifications:
- High school diploma / GED and 10 years of Engineering experience OR
- Associate’s degree and 8 years of Engineering experience OR
- Bachelor’s degree and 4 years of Engineering experience OR
- Master’s degree and 2 years of Engineering experience OR
- Doctorate degree
Preferred Qualifications:
- Demonstrated ability to lead the design of process equipment for new facilities and to balance competing factors to deliver equipment that meets process, quality and operability requirements.
- Financial acumen to deploy initiatives that add shareholder value
- Excellent communications skills, strong facilitation talent, and executive presence to drive cross functional objectives across Amgen’s international network
- Strong analytical skills to identify potential improvement opportunities
- Knowledge of industry trends (e.g., regulatory and compliance, technology, human performance programs, sustainability, asset insurance, etc.) to stay at the forefront of technology implementation
- Knowledge of applicable regulations (e.g. cGMP, building codes, Boiler and Pressure Vessel codes, etc.), to ensure compliance. Represent Amgen with outside firms, technical societies and regulatory bodies.
- Ability to develop, implement and utilize tools to drive efficiency in meeting business needs; establish measures and evaluate performance metrics.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Salary Range
123,098.00 USD - 149,145.00 USD
Career Category
Engineering
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
SENIOR ENGINEER - DRUG SUBSTANCE PROCESS ENGINEERING
What you will do
Let’s do this. Let’s change the world. In this vital role you will be responsible for planning, design, construction, operations and maintenance technical support of Amgen manufacturing infrastructure, worldwide. The Engineering Technical Authority (ETA) is responsible for technical direction, leadership, guidance and support for a specific array of process systems within an area of responsibility, such as Upstream Processes, Downstream Processes, Fill/Finish, CIP/SIP, Utilities, HVAC, Packaging, Devices, etc. Through their team(s) of global and site technical subject matter experts, the ETA will leverage engineering expertise both in the company and industry to optimize the life cycle management of Amgen’s assets and is accountable for performance and reliability across multiple sites.
This position is in the Drug Substance Process Systems Engineering team with an initial emphasis on capital project support for the DS facility at Amgen-North Carolina (ANC). Subsequent responsibilities will include end-to-end engineering support for future projects and technical global network management.
The successful candidate’s role will include responsibilities as a process equipment engineering lead delivering on design, construction & commissioning for ANC. This individual will be responsible for the successful design, integration, commissioning & qualification of a subset of process equipment on the ANC1 Expansion project. They will work with key partners to coordinate the successful delivery of qualified equipment to the site.
- Planning: Working with clients, as appropriate (e.g. PD, Quality, Manufacturing), develop and specify engineering standards, specifications, equipment selection and design. Develop metrics to support procurement strategies for equipment, inventory management, spares and preventative maintenance. Manage and track changes to specifications and standards, and system configuration.
- Design: Ensure adherence to standards and good engineering practices. Lead design of new systems in support of projects and new technology deployment. Ensure designs optimize the total life cycle of the asset, from both a cost and effectiveness standpoint.
- Construction: Use their ETA network to provide engineering support during the construction process, including responses to RFIs, resolving complex technical issues and conflicts, supporting overall project objectives.
- Commissioning: Ensure commissioning and qualification standards are developed and used. Use their network to provide engineering support to commissioning and qualification.
- Operations: Support development of, or approve operation procedures for the safe, efficient and effective operations of systems. Review performance data and make recommendations for improvement of system operations. Support NC/CAPA investigations related to equipment failures.
- Maintenance: Support systems failure analysis, approve maintenance standards and techniques. Support and review reliability and failure data, and implement actions to improve effectiveness, and reliability of systems. Assist the sites in system troubleshooting and take action as necessary to prevent future occurrence throughout network.
- Management: Lead their technical network. Makes use of expertise at the site and corporate levels for solving problems and deploying solutions across all sites. Identify and resolve issues and conflicts. Provide mentoring of other members in their network. Ensure technical decisions for assigned systems are optimized with those managed by other ETAs. Remain current on state-of-the-art for systems for adoption of new techniques and technology within Amgen. Represent Amgen with outside firms, technical societies and regulatory bodies.
This role involves travel up to 30% including overnight stays.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a person with these qualifications.
Basic Qualifications:
- High school diploma / GED and 10 years of Engineering experience OR
- Associate’s degree and 8 years of Engineering experience OR
- Bachelor’s degree and 4 years of Engineering experience OR
- Master’s degree and 2 years of Engineering experience OR
- Doctorate degree
Preferred Qualifications:
- Demonstrated ability to lead the design of process equipment for new facilities and to balance competing factors to deliver equipment that meets process, quality and operability requirements.
- Financial acumen to deploy initiatives that add shareholder value
- Excellent communications skills, strong facilitation talent, and executive presence to drive cross functional objectives across Amgen’s international network
- Strong analytical skills to identify potential improvement opportunities
- Knowledge of industry trends (e.g., regulatory and compliance, technology, human performance programs, sustainability, asset insurance, etc.) to stay at the forefront of technology implementation
- Knowledge of applicable regulations (e.g. cGMP, building codes, Boiler and Pressure Vessel codes, etc.), to ensure compliance. Represent Amgen with outside firms, technical societies and regulatory bodies.
- Ability to develop, implement and utilize tools to drive efficiency in meeting business needs; establish measures and evaluate performance metrics.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Salary Range
123,098.00 USD - 149,145.00 USD
See all 102+ Senior Software Engineering Jobs at Amgen
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Senior Software Engineering Jobs at Amgen.
Get Access To All JobsTips for Finding Senior Software Engineering Jobs at Amgen
Align your portfolio with biotech engineering
Amgen's engineering roles sit inside a regulated science environment. Highlight experience with data pipelines, cloud infrastructure, or systems that handle sensitive research data. Generic enterprise software experience matters less than domain-adjacent work.
Confirm your visa category before applying
Amgen sponsors multiple visa types for engineering roles, including H-1B, E-3, TN, and F-1 OPT. Know which category fits your nationality and current status before your first recruiter call so you can answer sponsorship questions without hesitation.
Request LCA details during offer negotiation
Before signing, ask your recruiter which prevailing wage level the Labor Condition Application will reflect. DOL wage levels directly affect your offer range, and understanding where your role sits helps you negotiate from an informed position.
Flag OPT STEM extension eligibility early
If you're on F-1 OPT, Amgen qualifies as an E-Verify employer, making you eligible for the 24-month STEM extension. Confirm your degree field aligns with the STEM OPT designated degree list before your start date to avoid gaps in work authorization.
Target roles in Amgen's tech and digital hubs
Senior Software Engineering openings at Amgen cluster around their Thousand Oaks headquarters and Tampa technology center. Use Migrate Mate to filter active roles by location and sponsorship type so you're applying where hiring activity is concentrated.
Prepare for a technical loop reflecting regulated systems
Amgen's engineering interviews often include system design questions involving data integrity, audit trails, or compliance-aware architecture. Practice scenarios where software correctness has downstream consequences in a scientific or clinical context.
Frequently Asked Questions
Does Amgen sponsor H-1B visas for Senior Software Engineers?
Yes, Amgen sponsors H-1B visas for Senior Software Engineering roles. The company has an established sponsorship process for this function, and engineering positions consistently appear in their sponsored filings. Because H-1B availability depends on the annual lottery, timing your application cycle and having your employer file promptly in March matters significantly for F-1 OPT holders approaching their cap-out date.
How do I apply for Senior Software Engineering jobs at Amgen?
Applications go through Amgen's careers portal. For international candidates, the most efficient approach is to filter specifically for roles that list visa sponsorship as available. Migrate Mate aggregates Amgen's Senior Software Engineering openings and filters by sponsorship type, so you can identify the right roles without manually screening dozens of listings that may not sponsor.
Which visa types does Amgen commonly use for Senior Software Engineering roles?
Amgen sponsors H-1B, E-3 visa, TN visa, and F-1 OPT for Senior Software Engineering positions, and supports Green Card sponsorship through EB-2 and EB-3 PERM for longer-tenured engineers. Australian citizens are well-positioned to use the E-3 visa pathway, which has no lottery and can be renewed indefinitely. Canadian and Mexican nationals in qualifying engineering roles may qualify under TN visa classification.
What qualifications does Amgen expect for Senior Software Engineering roles?
Amgen typically looks for a bachelor's or master's degree in computer science, software engineering, or a closely related field, combined with hands-on experience building scalable systems. For H-1B sponsorship, the role must qualify as a specialty occupation requiring at least a relevant bachelor's degree, which engineering positions at this level consistently meet. Experience with cloud platforms, data engineering, or scientific computing strengthens your candidacy significantly.
How do I handle H-1B timing if I'm on OPT and interviewing at Amgen?
If you're on F-1 OPT, USCIS requires your employer to file your H-1B petition during the April filing window for an October 1 start date. Coordinate with Amgen's immigration team early in the offer process to confirm they can meet that timeline. If you have STEM OPT, you have up to three additional years of work authorization, which reduces urgency and gives you more flexibility around the lottery cycle.