Systimmune Visa Sponsorship Jobs USA
Systimmune is a clinical-stage biopharmaceutical company developing next-generation antibody-based therapies. It sponsors H-1B visa and F-1 OPT visas, making it a viable target for international candidates in oncology, immunology, and related scientific disciplines looking to build a U.S.-based career in biotech.
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Get Access To All JobsLocation: Bothell, WA
Job Type: Full Time
Department: Process Development
Level: Mid Level
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discovery and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
The Research Associate II/Senior Research Associate will assist in downstream protein purification, protein characterization, and process development. The position will directly report to a Downstream lead and assist in downstream process development and tech transfer to a GMP manufacturing facility. In this role, the individual will assist and operate both routine and advanced analytical instruments as well as protein purification systems.
This position is full-time onsite at our new Bothell, WA location. This role may occasionally need to work outside normal work hours.
Key Responsibilities:
- Assist in downstream process development of molecules in pre-clinical and clinical pipelines. Process development activities include buffer preparation, chromatography method development and execution, TFF, and filtration operations and development
- Assist in performing routine purifications and analytical assays to support cell-line development, upstream, analytical, and formulation groups
- Execute development experiments to produce scalable and robust purification processes via affinity chromatography, IEX, HIC and CHT, etc., using the ÄKTA FPLC platform. Execute development experiments to produce scalable and robust viral inactivation, viral filtration and tangential flow filtration process
- Generate low endotoxin production runs for pre-clinical studies
- Perform routine HPLC/UPLC, CE, cIEF, octet, ELISA and other biophysical techniques to support upstream, downstream, and formulation process development
- Compile, analyze, and report data for process development, tech transfer documentation, and other internal partners
- Author standard operating procedures for biophysical assays and standard workflows
- Participate in timeline planning
- Other duties as assigned
Required Skills & Qualifications:
- MS or BS in Protein Science, Chemical Engineering, Biochemistry or a related field and relevant pharmaceutical or biotech experience
- Research Associate II - requires 2+ years of industry experience
- Senior Research Associate - requires BS with 5+ years of experience or MS degree with 3+ years of industry experience
- Experience with protein chromatography and filtration methods, and protein analysis techniques
- Ability to execute SOPs and biophysical assays, and experiments designed for process development of pipeline molecules independently
- Hands-on experience in:
- ÄKTA Protein Purification Systems and Unicorn software
- SEC-HPLC/UPLC
- Purification Process Development
- Crossflow and Tangential Flow Filtration techniques
- Column packing / unpacking
- Viral inactivation and viral filtration process development / Viral clearance study
- Low endotoxin production run
- Process scale-down/scale-up
Compensation and Benefits:
The expected base salary range for this position is $70,000 - $90,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.
Location: Bothell, WA
Job Type: Full Time
Department: Process Development
Level: Mid Level
SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials, SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discovery and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
The Research Associate II/Senior Research Associate will assist in downstream protein purification, protein characterization, and process development. The position will directly report to a Downstream lead and assist in downstream process development and tech transfer to a GMP manufacturing facility. In this role, the individual will assist and operate both routine and advanced analytical instruments as well as protein purification systems.
This position is full-time onsite at our new Bothell, WA location. This role may occasionally need to work outside normal work hours.
Key Responsibilities:
- Assist in downstream process development of molecules in pre-clinical and clinical pipelines. Process development activities include buffer preparation, chromatography method development and execution, TFF, and filtration operations and development
- Assist in performing routine purifications and analytical assays to support cell-line development, upstream, analytical, and formulation groups
- Execute development experiments to produce scalable and robust purification processes via affinity chromatography, IEX, HIC and CHT, etc., using the ÄKTA FPLC platform. Execute development experiments to produce scalable and robust viral inactivation, viral filtration and tangential flow filtration process
- Generate low endotoxin production runs for pre-clinical studies
- Perform routine HPLC/UPLC, CE, cIEF, octet, ELISA and other biophysical techniques to support upstream, downstream, and formulation process development
- Compile, analyze, and report data for process development, tech transfer documentation, and other internal partners
- Author standard operating procedures for biophysical assays and standard workflows
- Participate in timeline planning
- Other duties as assigned
Required Skills & Qualifications:
- MS or BS in Protein Science, Chemical Engineering, Biochemistry or a related field and relevant pharmaceutical or biotech experience
- Research Associate II - requires 2+ years of industry experience
- Senior Research Associate - requires BS with 5+ years of experience or MS degree with 3+ years of industry experience
- Experience with protein chromatography and filtration methods, and protein analysis techniques
- Ability to execute SOPs and biophysical assays, and experiments designed for process development of pipeline molecules independently
- Hands-on experience in:
- ÄKTA Protein Purification Systems and Unicorn software
- SEC-HPLC/UPLC
- Purification Process Development
- Crossflow and Tangential Flow Filtration techniques
- Column packing / unpacking
- Viral inactivation and viral filtration process development / Viral clearance study
- Low endotoxin production run
- Process scale-down/scale-up
Compensation and Benefits:
The expected base salary range for this position is $70,000 - $90,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s level qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.
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Get Access To All JobsTips for Finding Systimmune Visa Sponsorship Jobs USA
Target roles that align with Systimmune's core science
Systimmune's work centers on antibody-drug conjugates and bispecific antibodies. Roles in molecular biology, protein engineering, and clinical development are most likely to attract sponsorship consideration. Tailor your application to reflect direct experience in these therapeutic areas.
Understand F-1 OPT sponsorship before applying
Systimmune sponsors F-1 OPT, which means recent graduates can enter without immediate H-1B sponsorship. If your OPT window is active, lead with that flexibility, it lowers the barrier for a smaller biotech weighing sponsorship costs and timelines.
Position yourself for H-1B sponsorship early in the process
Systimmune sponsors H-1B visas, so research and scientific roles with clear degree requirements are strong candidates for sponsorship. Make sure your qualifications map directly to the specialty occupation standard before you apply.
Reach out through scientific and clinical networks
Clinical-stage biotechs like Systimmune hire selectively. Connections through oncology conferences, academic collaborations, or biotech industry groups can surface opportunities before they're widely posted. Warm introductions carry more weight at smaller organizations than cold applications.
Time your application around clinical development milestones
Hiring at clinical-stage companies often accelerates around trial phases or pipeline expansions. Monitoring Systimmune's clinical announcements can signal when teams are growing. Browse verified sponsors on Migrate Mate to track sponsorship-active companies in the same biotech space.
Be specific about your visa status and timeline upfront
Smaller biotechs appreciate candidates who are transparent about sponsorship needs and timelines from the first conversation. Clearly stating your current status, OPT expiration, and H-1B eligibility reduces friction and demonstrates preparation, qualities that matter in a focused scientific organization.
Frequently Asked Questions
Does Systimmune sponsor H-1B visas?
Yes, Systimmune sponsors H-1B visas. The company has an active sponsorship track record, primarily supporting scientific and research-oriented roles that meet the specialty occupation requirement. If you're targeting an H-1B with Systimmune, focus your application on positions with clear degree requirements in life sciences, biopharmaceutical development, or related technical fields.
What visa types does Systimmune sponsor?
Systimmune sponsors H-1B and F-1 OPT visas. The H-1B pathway suits candidates in specialty scientific and technical roles, while F-1 OPT sponsorship makes Systimmune accessible to recent graduates still within their post-degree work authorization window. At this time, the company does not have a documented track record of Green Card or E-3 visa sponsorship.
Which departments or roles at Systimmune are most likely to receive visa sponsorship?
Given Systimmune's focus on antibody-drug conjugates and immuno-oncology, roles in research and development, preclinical and clinical sciences, regulatory affairs, and bioanalytical functions are the most likely candidates for sponsorship. Positions requiring specialized graduate-level training in biology, chemistry, or pharmaceutical sciences align best with the H-1B specialty occupation standard that Systimmune applies.
How do I find open visa-sponsored jobs at Systimmune?
Migrate Mate surfaces verified visa-sponsoring companies so you can filter opportunities by real sponsorship history rather than guessing from job postings. Search for Systimmune directly on Migrate Mate to see current openings and confirm active sponsorship status before investing time in an application. This is especially useful if your timeline is tight and you need confirmed sponsors quickly.
How do I approach the application timeline when targeting Systimmune for H-1B sponsorship?
The H-1B cap lottery runs once a year, with registrations typically opening in March for an October 1 start date. If you're already on F-1 OPT, you may be able to begin work at Systimmune while your H-1B petition is pending. Start conversations with the hiring team well in advance of the registration window, ideally three to four months before March, so both sides have time to align on the petition process.