Director of Clinical Informatics Jobs

Director of Clinical Informatics jobs are open across health systems, academic medical centers, and regional hospitals, from manager-level to VP and C-suite, with specializations in EHR implementation, clinical decision support, and health data analytics. Find a role that fits below and apply directly.

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Overview

Open roles176+
Top stateCalifornia
Top employerCVS Health
Top citySacramento, CA
Work type46% On-site
Top industryHealthcare

Showing 5 of 176+ Director of Clinical Informatics jobs

Clinical Informatics Specialist
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New 22h ago
Clinical Informatics Specialist
Ascension
Milwaukee, Wisconsin
Biotech & Life Sciences
Clinical Trials
Healthcare Administration
$79k.88 - $146k.05/yr
Hybrid
High school diploma or GED
10,000+

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Pharmacist, Clinical Informatics
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Added 1d ago
Pharmacist, Clinical Informatics
Emplify Health
La Crosse, Wisconsin
Clinical Support
Healthcare Administration
Pharmacy
$125k - $188k/yr
Six Sigma Certification
5,001-10,000

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IT Clinical Informatics Pharmacist
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Added 1d ago
IT Clinical Informatics Pharmacist
Foundation Health Partners
Fairbanks, Alaska
Customer Success
Program Management
Project & Program Management
Project Management
$36.44 - $58.3/hr
Bachelor's degree
1,001-5,000

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Director Clinical Informatics and Practice Transformation-SWHR
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Added 1d ago
Director Clinical Informatics and Practice Transformation-SWHR
Southwestern Health Resources
Dallas, Texas
Business Operations
Business Strategy
Consulting & Professional Services
Hybrid
Master's degree
501-1,000

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Clinical Informatics Nurse
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Added 2d ago
Clinical Informatics Nurse
Cleveland Clinic
Cleveland, Ohio
Healthcare Administration
Nursing
Patient Services & Wellbeing
$70k - $106k.5/yr
Bachelor of Science
10,000+

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Director of Clinical Informatics Jobs by Experience Level

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Director of Clinical Informatics Job Market

Who's Hiring

  • CVS Health10
  • Cone Health5
  • Medpace4
  • Sutter Health4
  • Ascension3

Top Industries Hiring

  • Healthcare & Medical Services19
  • Insurance9
  • Biotechnology & Pharmaceuticals3
  • Education2
  • Science & Research2

What Employers Look For

The qualifications that appear most often in director of clinical informatics jobs.

  • Five or more years of clinical informatics or health IT leadership experience
  • Demonstrated expertise with major EHR platforms such as Epic or Cerner
  • Clinical background such as RN, MD, PharmD, or allied health licensure
  • Master's degree in health informatics, clinical informatics, or a related field
  • Experience leading EHR implementations, upgrades, or optimization initiatives
  • Board certification such as ABPM Clinical Informatics or CPHIMS preferred

Tips for Your Director of Clinical Informatics Job Search

Align your resume to EHR fluency

Hiring managers scan for specific platform experience, so name every EHR system you've configured or optimized, not just the vendor. Distinguish between end-user training, build work, and governance roles so committees can place your depth immediately.

Quantify workflow improvement outcomes

Generic phrases like 'improved efficiency' don't land at the director level. Replace them with concrete results: reduced duplicate order rates, shortened documentation time per encounter, or improved clinician adoption percentages after go-live.

Apply early to roles that fit

Migrate Mate lists director of clinical informatics openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Target postings that name your clinical domain

Openings written for ambulatory, inpatient, oncology, or perioperative informatics differ in scope and stakeholder expectations. Filter by specialty language in the posting so your application speaks directly to the clinical workflows they're hiring around.

Prepare a governance and committee story

Interviewers at the director level probe how you build physician buy-in and navigate change management across competing service lines. Prepare two or three specific examples of steering committee work, clinical workflow redesign, or policy adoption you led from proposal to rollout.

Negotiate scope before you negotiate title

Many director of clinical informatics offers look similar on paper but differ sharply in reporting structure, budget authority, and FTE oversight. Clarify whether the role owns the informatics team or shares resources, and what the capital request process looks like, before discussing compensation.

Director of Clinical Informatics Jobs: Frequently Asked Questions

Which companies are hiring the most director of clinical informaticss?

The companies hiring the most director of clinical informaticss right now include CVS Health, Cone Health, and Medpace, with the largest share of openings in California, North Carolina, and Texas, based on current listings on Migrate Mate as of November 2026. Large integrated health systems and academic medical centers account for the majority of active postings at this level.

How many director of clinical informatics jobs are remote?

About 54% of director of clinical informatics openings are fully remote or hybrid as of November 2026, though fully on-site roles remain common in organizations undergoing active EHR implementations or major system go-lives. Strategic and consultative informatics functions, such as clinical decision support governance and policy design, tend to offer more location flexibility than hands-on build and training roles.

How do you become a director of clinical informatics?

Start with direct patient care experience in a clinical role, then move into informatics coordination or analyst work where you build EHR configuration and workflow design skills. Progress to a manager or associate director position overseeing informatics projects, pursue a graduate degree in health informatics or clinical informatics, and obtain a certification such as ABPM Clinical Informatics or CPHIMS to demonstrate leadership-level credentialing to hiring committees.

Can you get hired as a director of clinical informatics without direct leadership experience?

Moving directly into a director title without prior leadership experience is uncommon, but candidates who have led cross-functional EHR projects, chaired clinical governance committees, or served as informal leads on major go-lives often make a strong case. Framing project leadership, stakeholder management, and physician engagement work as directional experience helps bridge the gap when formal management titles are absent from your record.

What does the director of clinical informatics interview process look like?

Most processes include an initial screening with HR or a talent team, followed by a panel interview with the CMIO, CNO, or CIO and clinical department heads, and often a final presentation round where you walk leadership through a past implementation or propose a strategy for a current organizational challenge. References from physician champions or clinical executives carry particular weight at the director level, so prepare those contacts early.

Where can I find and apply to director of clinical informatics jobs?

You can find and apply to director of clinical informatics jobs on Migrate Mate, which lists current openings from health systems, academic medical centers, and hospitals across the United States. Find roles that match your specialty background and experience level, then apply directly to each listing from the page.

See All 176+ Director of Clinical Informatics Jobs

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