Clinical Research Manager Green Card Jobs
Clinical Research Manager roles qualify for EB-2 and EB-3 green card sponsorship through the PERM labor certification process, which requires employers to document recruitment efforts before filing your I-140 petition. Pharmaceutical companies, CROs, and academic medical centers regularly sponsor foreign professionals for permanent residency in this field.
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Job Ref:
JR-3916
Location:
450 Brookline Ave, BOSTON, MA 02215
Category:
Clinical Research
Employment Type:
Full time
Work Location:
Hybrid: 2-3 days onsite/week
Salary/Pay Rate:
$70,000.00 - $85,300.00 per year
Overview
This Assistant Clinical Research Manager (ACRM) position will work within the Breast Oncology clinical research program and assist in the management of the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator. These positions, in collaboration with the program’s Clinical Research Managers, physicians, and research nursing staff, are responsible for assisting with the design, implementation, and evaluation of their program’s clinical research activities, related regulatory oversight, and will provide day-to-day supervision of their program’s clinical research staff as needed. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life-changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Clinical Trials Operations
- Assistant Clinical Research Managers (ACRM) will be responsible for assisting the Clinical Research Manager with the oversight of their disease group’s clinical trial portfolio and all related regulatory and compliance requirements.
- The ACRM will assist the CRM with all aspects of study start-up, active, and close-out activities for the group’s portfolio. They will be responsible for the required tracking of all protocol development, submission, review, and approval milestones.
- The ACRM will assist with the oversight of subject enrollment, protocol treatment, and follow-up care processes for protocol patients.
- Assist with the oversight of registration of protocol patients, study group registrar, and pharmaceutical company as outlined in protocol.
Regulatory & Compliance
- Assists in the responsibility for essential document compliance for the entire portfolio. Implements systems to monitor and ensure regulatory document collection and maintenance compliance.
- Assists in the responsibilities for all clinical trial reporting requirements; safety event, annual approval, deviations, etc. May implement systems to monitor portfolio compliance.
- Assists the study team to maintain an “audit ready” research environment.
Data Management & Clinical Trial Monitoring
- Assists CRM with responsibility for data management and compliance for the entire portfolio. Maintains schedules and procedures necessary for timely and complete data collection.
- Regularly reports data compliance status to key stakeholders; i.e. DFCI PI, study Sponsor, DFCI CTO. Helps to implement corrective action to maintain data compliance when necessary.
- Submits required “progress/tracking” reports to key stakeholders, when applicable.
Staff Training & Development
- Will assist the CRM with the recruitment and oversight of coordinator staff as well as ensure that staff have completed mandatory training in a timely manner.
- Will help implement program-specific onboarding and orientation process and may participate in annual performance evaluations and competency assessments of research staff as needed.
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:
- Must be able to perform day-to-day responsibilities independently with minimal supervision from managers.
- Has the ability to identify regulatory scenarios that require consultation.
- Has a good understanding of clinical trials start-up, active and close-out phases.
- Has a good understanding of clinical research, local policy, and federal regulation.
- Knowledge of cancer as a disease process, cancer treatment modalities, and the clinical trial process.
- In addition, has experience in protocol development, data compilation, and analysis.
- The ACRM will have a good understanding of the various tracking systems used to ensure timely data management by the clinical research staff.
- They will also understand Federal and State regulations as they relate to research. Strong interpersonal, organizational, and communication skills are required.
- Must have computer skills including the use of Microsoft Office.
MINIMUM JOB QUALIFICATIONS:
- Bachelor’s Degree required.
- Minimum of 3 plus years of related experience preferred.
- Must have the ability to function independently, think critically, and with good professional judgment.
License/Certification/Registration:
N/A
SUPERVISORY RESPONSIBILITIES:
No direct report
- Will provide day-to-day supervision for study management staff, including clinical research coordinators, students, volunteers, and other research assistants as needed.
PATIENT CONTACT:
May have contact with patients of all ages and populations.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEO Poster
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills, and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$70,000.00 - $85,300.00

Job Ref:
JR-3916
Location:
450 Brookline Ave, BOSTON, MA 02215
Category:
Clinical Research
Employment Type:
Full time
Work Location:
Hybrid: 2-3 days onsite/week
Salary/Pay Rate:
$70,000.00 - $85,300.00 per year
Overview
This Assistant Clinical Research Manager (ACRM) position will work within the Breast Oncology clinical research program and assist in the management of the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator. These positions, in collaboration with the program’s Clinical Research Managers, physicians, and research nursing staff, are responsible for assisting with the design, implementation, and evaluation of their program’s clinical research activities, related regulatory oversight, and will provide day-to-day supervision of their program’s clinical research staff as needed. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life-changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Clinical Trials Operations
- Assistant Clinical Research Managers (ACRM) will be responsible for assisting the Clinical Research Manager with the oversight of their disease group’s clinical trial portfolio and all related regulatory and compliance requirements.
- The ACRM will assist the CRM with all aspects of study start-up, active, and close-out activities for the group’s portfolio. They will be responsible for the required tracking of all protocol development, submission, review, and approval milestones.
- The ACRM will assist with the oversight of subject enrollment, protocol treatment, and follow-up care processes for protocol patients.
- Assist with the oversight of registration of protocol patients, study group registrar, and pharmaceutical company as outlined in protocol.
Regulatory & Compliance
- Assists in the responsibility for essential document compliance for the entire portfolio. Implements systems to monitor and ensure regulatory document collection and maintenance compliance.
- Assists in the responsibilities for all clinical trial reporting requirements; safety event, annual approval, deviations, etc. May implement systems to monitor portfolio compliance.
- Assists the study team to maintain an “audit ready” research environment.
Data Management & Clinical Trial Monitoring
- Assists CRM with responsibility for data management and compliance for the entire portfolio. Maintains schedules and procedures necessary for timely and complete data collection.
- Regularly reports data compliance status to key stakeholders; i.e. DFCI PI, study Sponsor, DFCI CTO. Helps to implement corrective action to maintain data compliance when necessary.
- Submits required “progress/tracking” reports to key stakeholders, when applicable.
Staff Training & Development
- Will assist the CRM with the recruitment and oversight of coordinator staff as well as ensure that staff have completed mandatory training in a timely manner.
- Will help implement program-specific onboarding and orientation process and may participate in annual performance evaluations and competency assessments of research staff as needed.
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:
- Must be able to perform day-to-day responsibilities independently with minimal supervision from managers.
- Has the ability to identify regulatory scenarios that require consultation.
- Has a good understanding of clinical trials start-up, active and close-out phases.
- Has a good understanding of clinical research, local policy, and federal regulation.
- Knowledge of cancer as a disease process, cancer treatment modalities, and the clinical trial process.
- In addition, has experience in protocol development, data compilation, and analysis.
- The ACRM will have a good understanding of the various tracking systems used to ensure timely data management by the clinical research staff.
- They will also understand Federal and State regulations as they relate to research. Strong interpersonal, organizational, and communication skills are required.
- Must have computer skills including the use of Microsoft Office.
MINIMUM JOB QUALIFICATIONS:
- Bachelor’s Degree required.
- Minimum of 3 plus years of related experience preferred.
- Must have the ability to function independently, think critically, and with good professional judgment.
License/Certification/Registration:
N/A
SUPERVISORY RESPONSIBILITIES:
No direct report
- Will provide day-to-day supervision for study management staff, including clinical research coordinators, students, volunteers, and other research assistants as needed.
PATIENT CONTACT:
May have contact with patients of all ages and populations.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEO Poster
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills, and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$70,000.00 - $85,300.00
See all 293+ Clinical Research Manager jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Clinical Research Manager roles.
Get Access To All JobsTips for Finding Green Card Sponsorship as a Clinical Research Manager
Translate your GCP credentials into PERM language
Your ICH-GCP training certificates, IRB experience, and phase-specific trial history need to map directly to the job duties listed on the PERM application. Gaps between your credentials and the posted requirements can trigger a USCIS Request for Evidence during I-140 review.
Target CROs with established PERM filing history
Contract research organizations running multi-site trials typically have in-house immigration teams and recurring PERM pipelines. Prioritize employers whose job postings explicitly name EB-2 or EB-3 sponsorship rather than relying on negotiating it after an offer.
Verify your role qualifies under EB-2 or EB-3
Clinical Research Manager positions requiring a master's degree or significant specialized experience often qualify for EB-2. Roles requiring a bachelor's degree with standard industry experience typically fall under EB-3. Confirm the classification with your employer before PERM is filed, since it affects your priority date strategy.
Search green card sponsorship jobs using Migrate Mate
Filter by employers with active PERM and I-140 filing histories for Clinical Research Manager roles using Migrate Mate. This surfaces companies already experienced with sponsoring this specific job title, cutting out employers who treat sponsorship as an afterthought.
Confirm the prevailing wage tier before accepting an offer
Your employer's offered salary must meet the DOL prevailing wage for your job zone and location. Look up the applicable wage level using the OFLC Wage Search before signing an offer letter, since a mismatch delays PERM certification and can require salary renegotiation mid-process.
Negotiate PERM filing timing into your start date planning
PERM labor certification currently averages well over a year at DOL. If you're transitioning from H-1B status, your employer needs to start the PERM process early enough to allow I-140 filing and adjustment of status without gaps in your authorized stay.
Clinical Research Manager jobs are hiring across the US. Find yours.
Find Clinical Research Manager JobsClinical Research Manager Green Card Sponsorship: Frequently Asked Questions
Do Clinical Research Manager roles typically qualify for EB-2 or EB-3 sponsorship?
Both categories apply depending on how the employer defines the position. Roles requiring a master's degree in a clinical or life sciences field, or a bachelor's degree with substantial specialized experience, often qualify for EB-2. Positions with a standard bachelor's degree requirement and defined industry experience typically fall under EB-3. Your employer's immigration counsel determines the classification when drafting the PERM job description.
How does green card sponsorship differ from H-1B for this role?
Green card sponsorship through PERM leads to permanent residency rather than temporary status, and EB-3 has no annual lottery. The tradeoff is time: PERM labor certification, I-140 approval, and adjustment of status or consular processing can take two to four years or longer depending on your country of birth and USCIS processing backlogs. H-1B gets you to work faster but requires renewal every three years and offers no permanent path on its own.
Which employers most commonly sponsor Clinical Research Managers for green cards?
Pharmaceutical manufacturers, contract research organizations, and large academic medical centers are the most consistent sponsors for this role. These employers typically have internal immigration teams and recurring PERM pipelines tied to clinical development headcount. Use Migrate Mate to find Clinical Research Manager positions with documented green card sponsorship history rather than applying broadly and asking about sponsorship during screening calls.
What happens to my PERM application if my employer changes the job duties?
Material changes to the job description after PERM is filed can invalidate the certification, requiring the employer to restart the process. Your job duties at the time of I-485 filing must also substantially match those described in the original PERM application. If your responsibilities shift significantly before your green card is approved, your employer's immigration counsel should assess whether an amended or new PERM filing is needed.
Does country of birth affect my green card timeline as a Clinical Research Manager?
Yes. EB-2 and EB-3 green cards are subject to per-country annual limits. Applicants born in India or China face multi-year backlogs because demand from those countries exceeds the annual allocation. Applicants born in most other countries, including Australia, the UK, and Canada, typically face far shorter waits under EB-3. Your priority date, which is set when PERM is filed or I-140 is submitted under EB-2, determines your place in the queue.
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