Green Card Medical Director Oncology Jobs
Medical Director Oncology roles qualify for EB-2 sponsorship when the position requires an advanced medical degree and specialized oncology expertise, or EB-3 for board-certified physicians in skilled roles. PERM labor certification is the standard first step, and many academic medical centers and cancer institutes actively support the full green card process.
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Get Access To All JobsMedical Lead Oncology, MA-US (NSCLC)
About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
Are you driven to make a real difference in the lives of patients?
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
Purpose & Scope
The Medical Lead Oncology, MA-US (Medical Affairs-United States), is accountable for the development and execution of medical and scientific strategies for one or more products within the Therapeutic Area (TA).
The Medical Lead Oncology, MA-US is responsible for:
- development of overall scientific and medical strategy for assigned product(s)
- creation and management of internal product/TA strategy and training
- strategic oversight and execution of data generation activities and other MA-US tactics
- review and endorsement of, and, in some cases, creation of scientific exchange materials, product launch planning/operations, and strategic congress planning, including collection and assessment of external medical insights to shape medical strategies
- representation of the US region within the Medical Affairs Team (MAT), as applicable
- collaboration with key stakeholders across the company to support business objectives for the US Region, leading the Regional Medical Team (RMT), as applicable, and ensuring alignment with and support of Medical Affairs (MA) colleagues within the region
- assessment of external medical environment perspectives and informing of medical strategies, including global strategies.
Role and Responsibilities
- Lead the development and execution of solid strategic medical plans for the assigned products within the TA that are aligned with the global Core Medical Plan (CMP)
- Lead external engagement with lung cancer experts, key opinion leaders, and professional organizations to generate actionable insights, shape medical strategy, and foster scientific collaboration.
- Accountable for oversight and execution of MA-sponsored clinical studies, as applicable
- Drive scientific and medical development and approval of sound study synopsis, protocols and study reports, including health economic & outcomes research (HEOR) related studies, ensuring clinical and scientific accuracy
- Align with peer leaders in the Commercial organization and cross-functional teams, providing strategic medical direction to support the needs of the business
- Demonstrate ability to collaborate and lead within matrix product/TA teams across multiple disciplines
- Represent MA-US on the relevant MAT, including representation of all regional needs and activities and timely execution of the CMP tactics, as applicable
- Provide medical expertise and approval of promotional materials
- Provide medical expertise and approval of non-promotional medical materials, including but not limited to slide presentations, local dossiers, health outcomes models, etc.
- Review and approve all standard and custom Medical Information response letters
- Initiate and support medical advisory boards within area of responsibility to understand and shape medical strategies
- Partner with medical science liaison (MSL) team in the field, effectively translating insights into regional and global strategy
- Collaborate with Regulatory Affairs and Pharmacovigilance in the development of product labeling and periodic safety reports, as applicable
- Lead scientific review of investigator sponsored research (ISR) proposals in the TA; may chair Regional ISR Committee, as applicable
- Provide medical expertise related to new product licensing and acquisition opportunities for the US
- Foster a culture of 100% compliance and embody One Astellas and the Astellas Way
Required Qualifications
- Educational Background: Doctoral Medicine Degree (MD, DO) preferred; PharmD or PhD will be considered
- Significant experience in lung cancer, including clinical, medical affairs or research expertise.
- Experience in working in matrix organization collaborating with medical, clinical, regulatory, health economic & outcome research, medical information, commercial and other organizational partners to deliver results
- Solid scientific analytical and problem-solving skills, strategic capabilities, project management and planning and organizational skills
- Ability to communicate effectively, including scientific concepts, both in writing and in oral presentations
- Ability to design and conduct various phases of clinical trials, including ability to critically review and analyze study designs
- Ability to effectively engage both internal and external stakeholders, customers and collaboration partners.
- Demonstrated ability to collaborate and build strategic alignment within the Medical Affairs community and across functions (e.g., Commercial).
- Fluent in written and verbal English
- Approximately 20% travel required
Preferred Qualifications
- Minimum 2 years Medical Affairs relevant experience within the pharmaceutical industry
- Medically Qualified with post graduate qualification and specialization in appropriate therapeutic specialty preferred
- Experience in medical research
- Extensive knowledge of US healthcare delivery systems (e.g. accountable care, managed care, pharmacy benefit management, government [Medicare, Medicaid]) and solid understanding of policy issues
Location and Working Environment
- This position is based in Northbrook, Illinois. Remote work from anywhere in the US is available.
- At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Travel is still required at around 20% for major congresses and internal meetings.
What awaits you at Astellas?
- Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
- Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
- Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
- A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.
Our Organizational Values and Behaviors
Values: Innovation, Integrity and Impact sit at the heart of what we do.
Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
Salary Range
$161,928-$281,000 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations.)
Benefits:
- Medical, Dental and Vision Insurance
- Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long Term Incentive Plan for eligible positions
- Company fleet vehicle for eligible positions
- Referral bonus program
LI-CH1
Medical Lead Oncology, MA-US (NSCLC)
About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
Are you driven to make a real difference in the lives of patients?
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
Purpose & Scope
The Medical Lead Oncology, MA-US (Medical Affairs-United States), is accountable for the development and execution of medical and scientific strategies for one or more products within the Therapeutic Area (TA).
The Medical Lead Oncology, MA-US is responsible for:
- development of overall scientific and medical strategy for assigned product(s)
- creation and management of internal product/TA strategy and training
- strategic oversight and execution of data generation activities and other MA-US tactics
- review and endorsement of, and, in some cases, creation of scientific exchange materials, product launch planning/operations, and strategic congress planning, including collection and assessment of external medical insights to shape medical strategies
- representation of the US region within the Medical Affairs Team (MAT), as applicable
- collaboration with key stakeholders across the company to support business objectives for the US Region, leading the Regional Medical Team (RMT), as applicable, and ensuring alignment with and support of Medical Affairs (MA) colleagues within the region
- assessment of external medical environment perspectives and informing of medical strategies, including global strategies.
Role and Responsibilities
- Lead the development and execution of solid strategic medical plans for the assigned products within the TA that are aligned with the global Core Medical Plan (CMP)
- Lead external engagement with lung cancer experts, key opinion leaders, and professional organizations to generate actionable insights, shape medical strategy, and foster scientific collaboration.
- Accountable for oversight and execution of MA-sponsored clinical studies, as applicable
- Drive scientific and medical development and approval of sound study synopsis, protocols and study reports, including health economic & outcomes research (HEOR) related studies, ensuring clinical and scientific accuracy
- Align with peer leaders in the Commercial organization and cross-functional teams, providing strategic medical direction to support the needs of the business
- Demonstrate ability to collaborate and lead within matrix product/TA teams across multiple disciplines
- Represent MA-US on the relevant MAT, including representation of all regional needs and activities and timely execution of the CMP tactics, as applicable
- Provide medical expertise and approval of promotional materials
- Provide medical expertise and approval of non-promotional medical materials, including but not limited to slide presentations, local dossiers, health outcomes models, etc.
- Review and approve all standard and custom Medical Information response letters
- Initiate and support medical advisory boards within area of responsibility to understand and shape medical strategies
- Partner with medical science liaison (MSL) team in the field, effectively translating insights into regional and global strategy
- Collaborate with Regulatory Affairs and Pharmacovigilance in the development of product labeling and periodic safety reports, as applicable
- Lead scientific review of investigator sponsored research (ISR) proposals in the TA; may chair Regional ISR Committee, as applicable
- Provide medical expertise related to new product licensing and acquisition opportunities for the US
- Foster a culture of 100% compliance and embody One Astellas and the Astellas Way
Required Qualifications
- Educational Background: Doctoral Medicine Degree (MD, DO) preferred; PharmD or PhD will be considered
- Significant experience in lung cancer, including clinical, medical affairs or research expertise.
- Experience in working in matrix organization collaborating with medical, clinical, regulatory, health economic & outcome research, medical information, commercial and other organizational partners to deliver results
- Solid scientific analytical and problem-solving skills, strategic capabilities, project management and planning and organizational skills
- Ability to communicate effectively, including scientific concepts, both in writing and in oral presentations
- Ability to design and conduct various phases of clinical trials, including ability to critically review and analyze study designs
- Ability to effectively engage both internal and external stakeholders, customers and collaboration partners.
- Demonstrated ability to collaborate and build strategic alignment within the Medical Affairs community and across functions (e.g., Commercial).
- Fluent in written and verbal English
- Approximately 20% travel required
Preferred Qualifications
- Minimum 2 years Medical Affairs relevant experience within the pharmaceutical industry
- Medically Qualified with post graduate qualification and specialization in appropriate therapeutic specialty preferred
- Experience in medical research
- Extensive knowledge of US healthcare delivery systems (e.g. accountable care, managed care, pharmacy benefit management, government [Medicare, Medicaid]) and solid understanding of policy issues
Location and Working Environment
- This position is based in Northbrook, Illinois. Remote work from anywhere in the US is available.
- At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Travel is still required at around 20% for major congresses and internal meetings.
What awaits you at Astellas?
- Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
- Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
- Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
- A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.
Our Organizational Values and Behaviors
Values: Innovation, Integrity and Impact sit at the heart of what we do.
Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
Salary Range
$161,928-$281,000 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations.)
Benefits:
- Medical, Dental and Vision Insurance
- Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long Term Incentive Plan for eligible positions
- Company fleet vehicle for eligible positions
- Referral bonus program
LI-CH1
See all 403+ Green Card Medical Director Oncology Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Green Card Medical Director Oncology Jobs.
Get Access To All JobsTips for Finding Green Card Sponsorship in Medical Director Oncology
Verify your board certification timing
PERM requires your employer to define minimum qualifications before advertising the role. If you're mid-certification, confirm your oncology board status will be complete before the I-140 is filed, not just when you start.
Target NCI-designated cancer centers first
NCI-designated cancer centers and large academic health systems have established immigration legal teams and routinely sponsor foreign oncologists through EB-2 and EB-3. Independent oncology practices rarely have the infrastructure to run a full PERM process.
Search green card sponsor history on Migrate Mate
Filter Medical Director Oncology roles by EB-2 and EB-3 sponsorship history using Migrate Mate. Seeing which employers have filed PERM applications for comparable roles tells you where sponsorship is a real institutional commitment, not a case-by-case decision.
Get a prevailing wage determination early
Your employer must submit a prevailing wage request to DOL before filing PERM. Use the OFLC Wage Search to look up wage levels for your specific SOC code and geographic area, so compensation negotiations don't stall the process later.
Distinguish EB-2 NIW from employer-sponsored EB-2
If your oncology research has national impact, a National Interest Waiver lets you self-petition under EB-2 without employer sponsorship or PERM. This path is separate from standard employer-sponsored EB-2 and bypasses the labor certification requirement entirely.
Align your H-1B gap with PERM filing windows
PERM advertising takes roughly 60 to 90 days before DOL submission, and adjudication can add several months. If you're on H-1B visa, confirm your employer files PERM before your sixth year so AC21 portability protections apply when you change roles.
Green Card Medical Director Oncology: Frequently Asked Questions
Does a Medical Director Oncology role qualify for EB-2 or EB-3 sponsorship?
Most Medical Director Oncology positions qualify for EB-2 because they require a medical degree plus specialized training, which meets the advanced-degree threshold. EB-3 applies when the role is defined as a skilled professional position. Your employer's immigration counsel typically makes this determination based on the job duties as written in the PERM application, not just your personal credentials.
How does green card sponsorship differ from H-1B for this role?
H-1B is a temporary nonimmigrant status that requires renewal and caps out at six years unless a green card is in process. EB-2 and EB-3 sponsorship leads to permanent residency with no recurring renewal cycles. PERM has no annual numerical cap at the category level for most countries, though per-country backlogs can affect Indian and Chinese nationals significantly. The green card process also involves PERM labor certification, which H-1B does not require.
What does the PERM labor certification process involve for oncology roles?
PERM requires your employer to conduct a DOL-mandated recruitment campaign proving no qualified U.S. worker is available for the position at the offered wage. For a Medical Director Oncology role, this includes job postings, internal notices, and documentation of all applicants reviewed. DOL then adjudicates the application, which currently takes several months. Only after PERM is certified can your employer file the I-140 immigrant petition on your behalf.
How do I find Medical Director Oncology jobs where employers already sponsor green cards?
Use Migrate Mate to filter oncology director roles by employers with documented EB-2 and EB-3 sponsorship history. This removes the guesswork of cold-applying and asking employers to start a process they've never run. Focusing on organizations with prior PERM filings in your specialty means you're talking to hiring managers who already understand what the process involves.
Can I change employers after PERM is filed without losing my place in the green card process?
Yes, under AC21 portability rules, you can change to a same or similar occupational role after your I-485 adjustment of status application has been pending for at least 180 days. For Medical Director Oncology, the key test is whether the new role falls under the same or a similar SOC code as the original PERM. USCIS reviews the job duties comparison, so document the overlap carefully before making any move.