Senior Bioinformatics Scientist Green Card Jobs
Senior Bioinformatics Scientist roles qualify for EB-2 sponsorship when the position requires an advanced degree in computational biology, bioinformatics, or a related field. Employers initiate PERM labor certification with DOL before filing an I-140 petition, making permanent residency the end goal rather than a temporary work authorization.
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Get Access To All JobsINTRODUCTION
Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.
We are looking for a highly motivated Senior Bioinformatics Scientist to join our Oncology Applications team!
As a Senior Bioinformatics Scientist, you will develop and apply computational methods for analyzing next-generation sequencing (NGS) data generated on Ultima's platform. This role will involve building robust pipelines, developing novel algorithms, collaborating cross-functionally with molecular biology, software engineering, and product teams, and driving insights from complex genomic datasets, with a focus on growing Oncology Applications.
This position is ideal for someone who thrives in a dynamic, fast-paced environment and can effectively balance multiple high-impact projects. In addition to core R&D responsibilities, you will contribute to external-facing scientific communications and support collaborations with customers and partners.
How You'll Contribute
- Develop, optimize, and maintain scalable bioinformatics pipelines for NGS data analysis such as WGS, WES, RNA-seq, and single-cell
- Design and implement novel algorithms for secondary and tertiary NGS analysis tailored to Ultima's sequencing chemistry
- Lead and execute multiple projects simultaneously, effectively prioritizing deliverables in alignment with evolving company goals
- Perform benchmarking and validation studies
- Analyze large-scale genomic datasets and generate actionable insights for internal R&D, product development, and external collaborators
- Collaborate closely with wet-lab scientists, software engineers, and product teams to translate experimental results into improved workflows and tools
- Support external collaborations by preparing technical analyses, reports, presentations, and data summaries for customers, partners, and conferences
- Contribute to scientific publications, application notes, white papers, and other external communication materials as needed
- Participate in customer-facing discussions to explain data analysis approaches, performance metrics, and platform capabilities
- Document methods clearly and communicate findings effectively to both technical and non-technical audiences
- Stay current with emerging technologies and advances in genomics, computational biology, machine learning, and cancer biology
- Other duties as assigned
BASIC QUALIFICATIONS
- PhD in Bioinformatics, Computational Biology, Genomics, Computer Science, or related field; or MS with significant industry experience
- PhD with 2+ years or MS with 5+ years of hands-on experience analyzing NGS data is required
- Strong programming skills in Python and/or C++
- Experience with common bioinformatics and somatic variant calling tools such as BWA, minimap2, GATK, samtools
- Proficiency in Linux/Unix environments and workflow management systems (Nextflow, Snakemake, WDL)
- Experience working with large datasets in cloud environments (AWS, GCP)
- Solid understanding of genomics and cancer biology
- Strong statistical and data analysis skills
- Demonstrated ability to manage multiple concurrent priorities and deliver high-quality work under tight timelines
- Knowledge of machine learning approaches applied to genomics
- Clear and confident communicator, comfortable in external-facing settings
- Experience in regulated environments (CLIA, CAP) is a plus
- Thrive in a fast-paced, startup environment with evolving priorities
- Demonstrated scientific rigor and analytical thinking
- High ownership, accountability, and bias toward action
- Collaborative mindset with cross-functional agility
COMPENSATION
- Salary Range: $115,000 - $145,000, if performed in the US
At Ultima Genomics, your base pay is one part of your total compensation package. Your actual base pay will depend on your skills, qualifications, experience, and location. Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits. This role is also eligible for a competitive benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending & health savings account; paid holidays; paid time off; employee assistance program; and other company benefits.
LI-Remote
Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws. See also Ultima Genomics' EEO Policy and Know Your Rights. If you have a disability or special need that requires accommodation, please let us know by contacting recruiting@ultimagen.com.
INTRODUCTION
Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.
We are looking for a highly motivated Senior Bioinformatics Scientist to join our Oncology Applications team!
As a Senior Bioinformatics Scientist, you will develop and apply computational methods for analyzing next-generation sequencing (NGS) data generated on Ultima's platform. This role will involve building robust pipelines, developing novel algorithms, collaborating cross-functionally with molecular biology, software engineering, and product teams, and driving insights from complex genomic datasets, with a focus on growing Oncology Applications.
This position is ideal for someone who thrives in a dynamic, fast-paced environment and can effectively balance multiple high-impact projects. In addition to core R&D responsibilities, you will contribute to external-facing scientific communications and support collaborations with customers and partners.
How You'll Contribute
- Develop, optimize, and maintain scalable bioinformatics pipelines for NGS data analysis such as WGS, WES, RNA-seq, and single-cell
- Design and implement novel algorithms for secondary and tertiary NGS analysis tailored to Ultima's sequencing chemistry
- Lead and execute multiple projects simultaneously, effectively prioritizing deliverables in alignment with evolving company goals
- Perform benchmarking and validation studies
- Analyze large-scale genomic datasets and generate actionable insights for internal R&D, product development, and external collaborators
- Collaborate closely with wet-lab scientists, software engineers, and product teams to translate experimental results into improved workflows and tools
- Support external collaborations by preparing technical analyses, reports, presentations, and data summaries for customers, partners, and conferences
- Contribute to scientific publications, application notes, white papers, and other external communication materials as needed
- Participate in customer-facing discussions to explain data analysis approaches, performance metrics, and platform capabilities
- Document methods clearly and communicate findings effectively to both technical and non-technical audiences
- Stay current with emerging technologies and advances in genomics, computational biology, machine learning, and cancer biology
- Other duties as assigned
BASIC QUALIFICATIONS
- PhD in Bioinformatics, Computational Biology, Genomics, Computer Science, or related field; or MS with significant industry experience
- PhD with 2+ years or MS with 5+ years of hands-on experience analyzing NGS data is required
- Strong programming skills in Python and/or C++
- Experience with common bioinformatics and somatic variant calling tools such as BWA, minimap2, GATK, samtools
- Proficiency in Linux/Unix environments and workflow management systems (Nextflow, Snakemake, WDL)
- Experience working with large datasets in cloud environments (AWS, GCP)
- Solid understanding of genomics and cancer biology
- Strong statistical and data analysis skills
- Demonstrated ability to manage multiple concurrent priorities and deliver high-quality work under tight timelines
- Knowledge of machine learning approaches applied to genomics
- Clear and confident communicator, comfortable in external-facing settings
- Experience in regulated environments (CLIA, CAP) is a plus
- Thrive in a fast-paced, startup environment with evolving priorities
- Demonstrated scientific rigor and analytical thinking
- High ownership, accountability, and bias toward action
- Collaborative mindset with cross-functional agility
COMPENSATION
- Salary Range: $115,000 - $145,000, if performed in the US
At Ultima Genomics, your base pay is one part of your total compensation package. Your actual base pay will depend on your skills, qualifications, experience, and location. Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits. This role is also eligible for a competitive benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending & health savings account; paid holidays; paid time off; employee assistance program; and other company benefits.
LI-Remote
Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws. See also Ultima Genomics' EEO Policy and Know Your Rights. If you have a disability or special need that requires accommodation, please let us know by contacting recruiting@ultimagen.com.
See all 7+ Senior Bioinformatics Scientist jobs
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Get Access To All JobsTips for Finding Green Card Sponsorship as a Senior Bioinformatics Scientist
Document your specialized computational biology credentials
Gather transcripts, publications, and project records that tie your degree directly to bioinformatics work. PERM requires the employer to define a minimum requirement, so your credentials need to match that stated job profile precisely.
Target biotech and pharma sponsors proactively
Search DOL PERM disclosure data to identify which biotech, pharma, and genomics employers have sponsored Bioinformatics Scientist roles before. Companies with prior PERM filings in this occupational category already understand the process and are far less likely to abandon your petition midway.
Use Migrate Mate to find active green card sponsors
Filter Senior Bioinformatics Scientist roles on Migrate Mate to surface employers with verified EB-2 and EB-3 sponsorship history. This saves significant time compared to manually cross-referencing job postings against PERM disclosure files.
Verify your role qualifies under EB-2 advanced-degree criteria
Check the O*NET profile for Bioinformatics Scientists to confirm the role is classified in a Job Zone requiring graduate-level education. USCIS evaluates whether the position inherently requires an advanced degree, not just whether your employer prefers one.
Clarify the PERM recruitment timeline before accepting an offer
Ask your hiring manager directly when PERM recruitment advertising would begin after your start date. DOL requires a specific recruitment period before the employer can file, so joining a company with no internal immigration infrastructure can delay your green card by a year or more.
Confirm employer willingness to sponsor EB-3 if your degree falls short
If your highest credential is a bachelor's degree plus professional experience, confirm the employer will pursue EB-3 rather than requiring EB-2 eligibility. Many bioinformatics roles can be structured under EB-3 professional classification, which still leads to permanent residency on the same PERM pathway.
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Find Senior Bioinformatics Scientist JobsSenior Bioinformatics Scientist Green Card Sponsorship: Frequently Asked Questions
Does a Senior Bioinformatics Scientist role qualify for EB-2 green card sponsorship?
Yes, if the position genuinely requires a master's degree or higher in bioinformatics, computational biology, or a closely related field. USCIS evaluates whether the advanced degree is a normal minimum for the occupation, not just an employer preference. Roles at research institutions, pharmaceutical companies, and genomics firms routinely qualify. If your degree is at the bachelor's level, the role can still qualify under EB-3 professional classification.
How does green card sponsorship differ from H-1B for this role?
H-1B grants temporary work authorization for up to six years, subject to an annual lottery cap. EB-2 and EB-3 green card sponsorship through the PERM process leads to permanent residency with no annual cap at the EB-3 level for most countries. The PERM filing itself takes roughly six to twelve months before the I-140 petition stage, making the total timeline longer than an H-1B transfer but the outcome permanent rather than temporary.
What does the PERM labor certification process look like for a bioinformatics role?
Your employer files a PERM application with DOL after conducting a mandatory recruitment period to demonstrate no minimally qualified U.S. workers are available. For a Senior Bioinformatics Scientist, the job description must accurately reflect the role's actual duties and minimum requirements. DOL then certifies the application, which your employer uses to file the I-140 immigrant petition with USCIS. The PERM certification is employer-specific and non-transferable.
Which employers actively sponsor green cards for Senior Bioinformatics Scientists?
Pharmaceutical companies, biotech firms, academic medical centers, and genomics research organizations are the most consistent sponsors for this role. You can verify sponsorship history by searching DOL PERM disclosure data filtered by the bioinformatics occupational category. Migrate Mate aggregates this data so you can browse Senior Bioinformatics Scientist openings from employers with confirmed EB-2 and EB-3 filing history without manually parsing government databases.
Can I switch employers after my I-140 is approved without losing my green card progress?
Once your I-140 has been approved for 180 days and your I-485 adjustment-of-status application has been pending for at least 180 days, federal portability rules allow you to change to a same or similar occupational role without restarting the process. Bioinformatics roles across different employers generally satisfy the same-or-similar test. Confirm the new role's SOC code and job duties align closely with the approved I-140 before accepting any offer.
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