H-1B Visa Operations Manager Jobs
Operations Manager roles qualify for H-1B sponsorship under the specialty occupation standard when the position requires a bachelor's degree in business, industrial engineering, supply chain, or a directly related field. Large manufacturers, logistics firms, and healthcare networks sponsor consistently. The annual cap applies, so timing your job search around the April lottery window matters.
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Get Access To All JobsINTRODUCTION
Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
ABOUT THE ROLE
BillionToOne is looking for a People Operations Manager to join our growing People team and play a critical role in scaling our people programs, systems, and operations. This role will own and enhance core People Ops programs while serving as a key partner in driving operational excellence, vendor strategy, and data-informed decision-making.
The ideal candidate brings deep expertise in benefits, strong program and project management skills, and a data-driven mindset, with the ability to anticipate needs and proactively improve processes in a fast-paced, high-growth environment.
This is a hybrid role (2–3 days onsite per week at our Menlo Park and/or Union City office) reporting to the Associate Director of People Operations.
Responsibilities:
- Design, optimize, and scale core People Ops programs (onboarding, offboarding, performance cycles, engagement/recognition, and compliance), driving strategy, scalability, and continuous improvement
- Own and scale benefits strategy and operations, serving as the primary lead for vendor partnerships (benefits brokers, payroll providers, etc.)
- Act as the program manager for performance cycles, driving end-to-end execution, stakeholder alignment, and continuous improvement
- Design and implement scalable processes and systems, proactively identifying gaps and driving operational efficiency
- Partner with the Associate Director to operationalize strategic initiatives (e.g., recognition program, engagement survey, etc.)
- Maintain strong policy and compliance knowledge, recommending updates to enhance both compliance and employee experience
- Serve as the Tier 2 escalation point for complex employee inquiries, resolving issues independently and escalating only critical matters as needed
QUALIFICATIONS
- 5+ years of experience in People Operations, HR Generalist, or similar roles, preferably in a high-growth or startup environment
- Strong expertise in benefits administration and vendor management
- Proven experience leading cross-functional programs or cycles (e.g., performance management, compensation, or engagement programs)
- Demonstrated ability to design and improve scalable processes and systems
- Strong analytical skills with experience using data to drive decisions
- Excellent project management, organizational, and prioritization skills
- Strong communication skills with the ability to influence and partner across levels
- High attention to detail, sound judgment, and a proactive mindset
- “Scrappy,” solutions-oriented approach with a focus on continuous improvement
- Previous experience in start-up is highly desired
BENEFITS AND PERKS:
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
- Daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, we offer a total compensation package of $259,893 per year, including a base pay range of $139,340 - $160,777 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
INTRODUCTION
Ready to redefine what's possible in molecular diagnostics? Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
ABOUT THE ROLE
BillionToOne is looking for a People Operations Manager to join our growing People team and play a critical role in scaling our people programs, systems, and operations. This role will own and enhance core People Ops programs while serving as a key partner in driving operational excellence, vendor strategy, and data-informed decision-making.
The ideal candidate brings deep expertise in benefits, strong program and project management skills, and a data-driven mindset, with the ability to anticipate needs and proactively improve processes in a fast-paced, high-growth environment.
This is a hybrid role (2–3 days onsite per week at our Menlo Park and/or Union City office) reporting to the Associate Director of People Operations.
Responsibilities:
- Design, optimize, and scale core People Ops programs (onboarding, offboarding, performance cycles, engagement/recognition, and compliance), driving strategy, scalability, and continuous improvement
- Own and scale benefits strategy and operations, serving as the primary lead for vendor partnerships (benefits brokers, payroll providers, etc.)
- Act as the program manager for performance cycles, driving end-to-end execution, stakeholder alignment, and continuous improvement
- Design and implement scalable processes and systems, proactively identifying gaps and driving operational efficiency
- Partner with the Associate Director to operationalize strategic initiatives (e.g., recognition program, engagement survey, etc.)
- Maintain strong policy and compliance knowledge, recommending updates to enhance both compliance and employee experience
- Serve as the Tier 2 escalation point for complex employee inquiries, resolving issues independently and escalating only critical matters as needed
QUALIFICATIONS
- 5+ years of experience in People Operations, HR Generalist, or similar roles, preferably in a high-growth or startup environment
- Strong expertise in benefits administration and vendor management
- Proven experience leading cross-functional programs or cycles (e.g., performance management, compensation, or engagement programs)
- Demonstrated ability to design and improve scalable processes and systems
- Strong analytical skills with experience using data to drive decisions
- Excellent project management, organizational, and prioritization skills
- Strong communication skills with the ability to influence and partner across levels
- High attention to detail, sound judgment, and a proactive mindset
- “Scrappy,” solutions-oriented approach with a focus on continuous improvement
- Previous experience in start-up is highly desired
BENEFITS AND PERKS:
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousands patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
- Daily on-site lunches provided from top eateries
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).
For this position, we offer a total compensation package of $259,893 per year, including a base pay range of $139,340 - $160,777 per year.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
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Get Access To All JobsTips for Finding H-1B Visa Sponsorship as an Operations Manager
Verify your role meets specialty occupation
Operations Manager titles vary widely. Pull the O*NET profile for your specific function and confirm the position requires a field-specific degree, not just any bachelor's. Generalist management roles with no degree-field requirement draw the most H-1B RFEs.
Target employers with LCA filing history
Search Migrate Mate to filter Operations Manager roles by employers with verified DOL Labor Condition Application filings. Employers already in the LCA system have cleared prevailing-wage certification before and are faster to sponsor new hires.
Check prevailing wage before salary negotiations
Use the OFLC Wage Search to look up the Level I through Level IV wage for your SOC code and metro area before accepting an offer. Your employer must pay at or above the prevailing wage on the LCA, so knowing the floor protects you in negotiations.
Prioritize cap-exempt employers during the lottery
Universities, nonprofit research organizations, and government entities are cap-exempt. An Operations Manager role at a university facilities department or a hospital affiliated with a medical school can bypass the April lottery entirely and file any time.
Document business process ownership in your petition
USCIS scrutinizes Operations Manager petitions for evidence of specialty occupation. Your employer's I-129 support letter should detail the degree fields required for your specific duties, not just list your title. Generic job descriptions are a leading cause of RFEs in this SOC category.
Use premium processing if your start date is tight
USCIS offers premium processing for I-129 petitions, which guarantees a 15-business-day adjudication decision. If you're transitioning from OPT or a cap-gap period, the faster timeline reduces the gap between your current authorization end date and H-1B approval.
Operations Manager jobs are hiring across the US. Find yours.
Find Operations Manager JobsOperations Manager H-1B Visa: Frequently Asked Questions
Does an Operations Manager role qualify as a specialty occupation for H-1B purposes?
It depends on how the position is defined. USCIS requires that the role normally requires a bachelor's degree or higher in a specific field, not just any degree. An Operations Manager overseeing supply chain systems, industrial engineering, or healthcare operations with a field-specific degree requirement generally qualifies. Broad generalist roles without a defined degree field are more likely to receive an RFE.
Which employers sponsor H-1B visas for Operations Manager positions?
Manufacturing companies, logistics and third-party logistics firms, healthcare systems, and large retailers sponsor Operations Manager roles most consistently. These industries have recurring needs for specialized operations talent and are familiar with the LCA and I-129 process. You can browse employers with verified H-1B filing history for this role on Migrate Mate.
What happens to my H-1B status if I get promoted from Operations Manager to a Director role?
A significant change in job duties, title, or work location requires your employer to file an amended I-129 petition with USCIS before the change takes effect. Moving from Operations Manager to Director typically involves a material change in duties and wage level, which triggers the amendment requirement. Your employer should file before the promotion date to keep your status current.
Can an Operations Manager role at a nonprofit bypass the H-1B cap?
Yes, if the employer qualifies as a cap-exempt institution. Nonprofits affiliated with universities or government research organizations are cap-exempt under the INA. An Operations Manager position at a qualifying institution can be filed with USCIS at any time of year without waiting for the April lottery, including mid-year transfers from a cap-subject employer.
How does a multi-site Operations Manager role affect the H-1B petition?
If your role requires you to work at multiple locations, your employer must include all worksites on the LCA and, in most cases, post the LCA notice at each location. USCIS and DOL both scrutinize multi-site petitions for compliance. Short-term placements at client sites under a year may follow different rules, so your employer should confirm the worksite structure with their immigration counsel before filing.
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