H-1B Visa Postdoctoral Research Fellow Jobs
Postdoctoral Research Fellow positions at U.S. universities and research institutions are among the most common H-1B visa specialty occupation roles, with employers regularly filing petitions for researchers in STEM, social sciences, and humanities. Many institutions are cap-exempt, meaning your petition can be filed year-round without waiting for the annual lottery.
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Get Access To All JobsINTRODUCTION
The Computational Regulatory Genomics Laboratory at the Cincinnati Children’s Hospital Medical Center (CCHMC) is seeking a highly motivated Postdoctoral Research Fellow. The primary research focus of the lab is to understand the fundamental mechanisms of gene transcriptional regulation across various biological contexts, including developmental biology, cancer biology, and metabolism. We are specifically interested in enhancer regulation and systems-level understanding of enhancer architectures and functions across diverse biological contexts. We integrate multi-omics data, including ChIP-seq, ChIP-exo, CUT&RUN, GRO-seq, csRNA-seq, RNA-seq, ATAC-seq, Hi-C, and single-cell technologies, to delineate heterogeneous architectures of transcription factor binding events and chromatin landscapes at high resolution. The lab collaborates with multiple experimental laboratories specialized in metabolism, cancer, and development. The lab’s work has been published in many high-profile journals, including Nature, Cell Metabolism, Molecular Cell, Genes & Development, Circulation, Nature Communications, and the Journal of Clinical Investigation.
ROLE AND RESPONSIBILITIES
JOB RESPONSIBILITIES
-
Perform analysis and experiments - Design, execute, and record analysis and experiments; apply standard scientific protocols to research, and improve current methods and evaluate innovative techniques. Develop and implement human subject research protocols, vertebrate animal research protocols and design experimental procedures and documentation in accordance with the relevant laws and regulations. Prepare, clean and analyze data. Maintain optimal protocol and accuracy by conducting regular quality and reproducibility checks.
-
Communicate results/findings - Draft, write, and edit scientific reports, papers, journal articles, and abstracts. Present information on research and department work to others at department meetings, journal clubs, and seminars. Present results and discuss relevant insights with Faculty and provide useful recommendations and analysis.
-
Innovate and advance departmental capabilities - Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current analysis/experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all analysis and experiments. Develop, set-up, and verify new procedures in the department. Standardize and establish new published procedures; evaluate innovative techniques. Develop new protocols; design formats. Maintain an integral role in the department's meetings, presentations, and publications. Troubleshoot and correct erroneous results or problems with department software/equipment. Maintain and repair software/equipment; monitor proper use by personnel.
-
Financial/Budgeting - Assist in preparing grant applications. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve, and initiate check requests; track funding, maintain accurate balance, and resolve any discrepancies.
-
Staff Leadership - May provide day-to-day functional leadership for a team or directly manage a minimal number of support staff. Establishes team goals. Gives input into, and performs employee performance reviews. Oversees and guides work assignments. Serves as the functional expert and provides guidance to the team.
-
Education and Training - May serve as course master and develop new courses at the undergraduate and graduate level, including appropriate plans for evaluating student performance; may deliver lectures as a guest lecturer in courses organized by other faculty. Assist in the training of new employees. Serve as a resource and/or mentor to coworkers. Assist in the development and presentation of department training. Identify training needs and provide necessary coaching.
JOB QUALIFICATIONS
- Ph.D. in related discipline, MD, or equivalent degree
Preferred:
- PhD in Computer Science, Physics, Biomedical Informatics, Bioinformatics, Epidemiology, Biostatistics or other similar quantitative disciplines
Preferred:
- Experience in a related discipline
About us
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.
Cincinnati Children's is:
-
Recognized by U.S. News & World Report as a top 10 best Children's Hospitals in the nation for more than 15 years
-
Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH) Funding
-
Recognized as one of America’s Best Large Employers (2025), America’s Best Employers for New Grads (2025)
-
One of the nation's America’s Most Innovative Companies as noted by Fortune
-
Consistently certified as great place to work
-
A Leading Disability Employer as noted by the National Organization on Disability
-
Magnet® designated for the fourth consecutive time by the American Nurses Credentialing Center (ANCC)
We Embrace Innovation—Together. We believe in empowering our teams with the tools that help us work smarter and care better. That’s why we support the responsible use of artificial intelligence. By encouraging innovation, we’re creating space for new ideas, better outcomes, and a stronger future—for all of us.
Comprehensive job description provided upon request.
Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability
LOCATION
Primary Location Exploration Avenue
Department
Biomedical Informatics
Shift
Day (United States of America)
Schedule
Full time
Weekly Hours
40
FTE
1
Employee Status
Regular
INTRODUCTION
The Computational Regulatory Genomics Laboratory at the Cincinnati Children’s Hospital Medical Center (CCHMC) is seeking a highly motivated Postdoctoral Research Fellow. The primary research focus of the lab is to understand the fundamental mechanisms of gene transcriptional regulation across various biological contexts, including developmental biology, cancer biology, and metabolism. We are specifically interested in enhancer regulation and systems-level understanding of enhancer architectures and functions across diverse biological contexts. We integrate multi-omics data, including ChIP-seq, ChIP-exo, CUT&RUN, GRO-seq, csRNA-seq, RNA-seq, ATAC-seq, Hi-C, and single-cell technologies, to delineate heterogeneous architectures of transcription factor binding events and chromatin landscapes at high resolution. The lab collaborates with multiple experimental laboratories specialized in metabolism, cancer, and development. The lab’s work has been published in many high-profile journals, including Nature, Cell Metabolism, Molecular Cell, Genes & Development, Circulation, Nature Communications, and the Journal of Clinical Investigation.
ROLE AND RESPONSIBILITIES
JOB RESPONSIBILITIES
-
Perform analysis and experiments - Design, execute, and record analysis and experiments; apply standard scientific protocols to research, and improve current methods and evaluate innovative techniques. Develop and implement human subject research protocols, vertebrate animal research protocols and design experimental procedures and documentation in accordance with the relevant laws and regulations. Prepare, clean and analyze data. Maintain optimal protocol and accuracy by conducting regular quality and reproducibility checks.
-
Communicate results/findings - Draft, write, and edit scientific reports, papers, journal articles, and abstracts. Present information on research and department work to others at department meetings, journal clubs, and seminars. Present results and discuss relevant insights with Faculty and provide useful recommendations and analysis.
-
Innovate and advance departmental capabilities - Independently reproduce, evaluate, research, and improve techniques currently used. Adapt new methods to existing procedures and modify current analysis/experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all analysis and experiments. Develop, set-up, and verify new procedures in the department. Standardize and establish new published procedures; evaluate innovative techniques. Develop new protocols; design formats. Maintain an integral role in the department's meetings, presentations, and publications. Troubleshoot and correct erroneous results or problems with department software/equipment. Maintain and repair software/equipment; monitor proper use by personnel.
-
Financial/Budgeting - Assist in preparing grant applications. Assist in preparing, writing, and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve, and initiate check requests; track funding, maintain accurate balance, and resolve any discrepancies.
-
Staff Leadership - May provide day-to-day functional leadership for a team or directly manage a minimal number of support staff. Establishes team goals. Gives input into, and performs employee performance reviews. Oversees and guides work assignments. Serves as the functional expert and provides guidance to the team.
-
Education and Training - May serve as course master and develop new courses at the undergraduate and graduate level, including appropriate plans for evaluating student performance; may deliver lectures as a guest lecturer in courses organized by other faculty. Assist in the training of new employees. Serve as a resource and/or mentor to coworkers. Assist in the development and presentation of department training. Identify training needs and provide necessary coaching.
JOB QUALIFICATIONS
- Ph.D. in related discipline, MD, or equivalent degree
Preferred:
- PhD in Computer Science, Physics, Biomedical Informatics, Bioinformatics, Epidemiology, Biostatistics or other similar quantitative disciplines
Preferred:
- Experience in a related discipline
About us
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.
Cincinnati Children's is:
-
Recognized by U.S. News & World Report as a top 10 best Children's Hospitals in the nation for more than 15 years
-
Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH) Funding
-
Recognized as one of America’s Best Large Employers (2025), America’s Best Employers for New Grads (2025)
-
One of the nation's America’s Most Innovative Companies as noted by Fortune
-
Consistently certified as great place to work
-
A Leading Disability Employer as noted by the National Organization on Disability
-
Magnet® designated for the fourth consecutive time by the American Nurses Credentialing Center (ANCC)
We Embrace Innovation—Together. We believe in empowering our teams with the tools that help us work smarter and care better. That’s why we support the responsible use of artificial intelligence. By encouraging innovation, we’re creating space for new ideas, better outcomes, and a stronger future—for all of us.
Comprehensive job description provided upon request.
Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability
LOCATION
Primary Location Exploration Avenue
Department
Biomedical Informatics
Shift
Day (United States of America)
Schedule
Full time
Weekly Hours
40
FTE
1
Employee Status
Regular
See all 98+ H-1B Visa Postdoctoral Research Fellow Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new H-1B Visa Postdoctoral Research Fellow Jobs.
Get Access To All JobsTips for Finding H-1B Visa Sponsorship in Postdoctoral Research Fellow
Verify your institution's cap-exempt status
Universities, nonprofit research organizations, and government research entities are typically cap-exempt under USCIS rules. Confirm this before accepting an offer, cap-exempt employers can file your H-1B petition any time of year, not just during the April lottery window.
Document your specialty occupation with O*NET
Pull the O*NET occupation profile for Postsecondary Teachers or your specific research discipline. Use it to show your role requires a directly related bachelor's degree or higher, which is the core H-1B specialty occupation requirement USCIS scrutinizes.
Check prevailing wage before negotiating your offer
Run your job title, SOC code, and work location through the OFLC Wage Search before finalizing compensation. Your employer's LCA must certify a wage at or above the DOL prevailing wage level, and a mismatch can delay certification or trigger a compliance issue.
Search postdoc roles on Migrate Mate by LCA history
Filter Migrate Mate's job board by employers with verified H-1B LCA filing history in your research field. This surfaces institutions that have actively sponsored postdocs before, cutting out the back-and-forth of asking HR whether they sponsor.
Time your F-1 OPT end date against the H-1B filing window
If you're transitioning from F-1 OPT, your employer must file Form I-129 before your OPT expires. For cap-exempt institutions, this is flexible, but plan a 90-day lead time to allow for LCA certification and petition preparation before your authorization lapses.
Request a written sponsorship commitment before you resign
Ask the principal investigator or HR to confirm in writing that the institution will sponsor your H-1B, cover filing fees, and retain you for the petition's validity period. Verbal assurances from a PI don't bind the university's HR or sponsored programs office.
H-1B Visa Postdoctoral Research Fellow: Frequently Asked Questions
Do most postdoctoral research positions qualify as H-1B specialty occupations?
Yes. Postdoctoral Research Fellow roles almost universally qualify because they require at minimum a doctorate or equivalent in a directly related field. USCIS classifies these positions under specialty occupation rules, and the required-degree connection is straightforward for research roles in STEM, social sciences, and humanities. The employer documents this in the H-1B petition using the job description and your credentials.
Can a university sponsor my H-1B without going through the lottery?
Most universities, colleges, and affiliated nonprofit research institutions are cap-exempt under the H-1B rules. This means they can file your petition at any point in the year and bypass the annual 85,000-slot cap entirely. Confirm your specific employer's cap-exempt status with their sponsored programs or HR office before counting on this, since not every affiliated entity qualifies automatically.
How do I find postdoc employers with a track record of H-1B sponsorship?
Migrate Mate lets you search Postdoctoral Research Fellow positions filtered by employers with verified H-1B LCA filing history. This shows you which institutions have actively filed for researchers in your field, so you're not starting conversations with employers who have no process in place. DOL LCA disclosure data is public and updated quarterly, making it a reliable proxy for sponsorship track record.
Who pays the H-1B filing fees for a postdoc position?
USCIS prohibits employers from passing certain mandatory H-1B filing fees to the employee. The base I-129 petition fee and the asylum program fee must be paid by the employer. Premium processing is optional and sometimes negotiable. Universities often have standard sponsored programs policies on fee coverage, so ask HR specifically which fees the institution absorbs before your petition is filed.
What happens to my H-1B status if my postdoc funding runs out or the grant ends?
Your H-1B status is tied to your specific employer and position. If your grant ends and the institution can no longer employ you, your authorized period of stay ends with it. You have a 60-day grace period after your last day of employment to find a new sponsor, change status, or depart. If a new institution wants to hire you, they file a new H-1B transfer petition, which can be filed while you're still within the grace period.