H-1B Visa Senior Bioinformatics Scientist Jobs
Senior Bioinformatics Scientist roles sit firmly within H-1B visa specialty occupation territory, requiring at least a bachelor's degree in bioinformatics, computational biology, or a closely related field. Employers filing LCAs for this SOC code must meet DOL prevailing wage requirements, and many biotech and pharma sponsors have established H-1B filing histories you can verify before applying.
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Pay Range: $155,000.00 - $175,000.00 / year
Salary offers are based on a wide range of factors including relevant skills, training, experience, education, and, where applicable, certifications obtained. Market and organizational factors are also considered. Successful candidates may be eligible to receive annual performance bonus compensation.
Benefits Information:
We are proud to offer best-in-class benefits and programs to support employees and their families in living healthy, happy lives. Our pay and benefit plans have been designed to promote employee health in all respects – physical, financial, and developmental. Depending on whether it is a part-time or full-time position, some of the benefits offered may include:
- Day 1 Medical, supplemental health, dental & vision for FT employees who work 30+ hours
- Best-in-class well-being programs
- Annual, no-cost health assessment program Blueprint for Wellness®
- healthyMINDS mental health program
- Vacation and Health/Flex Time
- 6 Holidays plus 1 "MyDay" off
- FinFit financial coaching and services
- 401(k) pre-tax and/or Roth IRA with company match up to 5% after 12 months of service
- Employee stock purchase plan
- Life and disability insurance, plus buy-up option
- Flexible Spending Accounts
- Annual incentive plans
- Matching gifts program
- Education assistance through MyQuest for Education
- Career advancement opportunities
- and so much more!
At Quest, we are on a continuous journey of discovery and development. It’s this attitude that has made us an industry leader and the #1 Diagnostic Lab in the US. For those joining us, we offer exciting and fast-moving career opportunities where you can affect change at a rate unheard of in many organizations of our size and scope. While we invest in and develop technology to drive our innovations, our ongoing success relies on our people.
Quest Diagnostics Specialty Genetics products provide specific answers that clinicians need to deliver the appropriate diagnostic and prognostic care to their patients. You will work for the world leader in the industry, with a career where you will have the opportunity to collaborate and affect change while expanding your leadership skills and technical knowledge. You can make a real impact in a market that is growing and developing.
The Lead Bioinformatics Engineer - Variant Interpretation is responsible for advancing patient care through innovative software solutions. The successful candidate will design, implement, and maintain web applications handling large-scale genetic data. Collaborating closely with the Data Science and Bioinformatics teams, the engineer will work in an agile environment, contributing to the modernization of our systems while enhancing their own technical skills.
Quest Diagnostics honors our service members and encourages veterans to apply.
While we appreciate and value our staffing partners, we do not accept unsolicited resumes from agencies. Quest will not be responsible for paying agency fees for any individual as to whom an agency has sent an unsolicited resume.
Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets or any other legally protected status.
Feature Development:
- Design, implement, and maintain web application features using Node, TypeScript, React, MongoDB, Next.js, and NestJS.
- Execute on achieving user requirements and performance standards in a medical or diagnostics information environment.
System Transition:
- Transition legacy systems from PHP, Go, and Angular to Node, Python and React.
- Help refactor and optimize existing codebases related to clinical or genomic data.
Database Management:
- Design, query, and manage data in MySQL, and MongoDB in compliance with business data privacy requirements.
Cloud Deployment:
- Support deployment and management of applications on AWS to ensure scalability, reliability, and security in a healthcare context.
Agile Collaboration:
- Participate in agile workflows, including sprint planning, daily stand-ups, and retrospectives.
- Collaborate with cross-functional teams to ensure seamless integration and delivery.
Quality Assurance:
- Write unit, integration, and end-to-end tests to ensure code quality.
- Conduct peer code reviews to uphold development standards.
Lead Specific Responsibilities:
- Provide guidance & create design and code standards for developer team.
- Ensure standards being met during peer and similar reviews.
- Lead and provide technical training for team members.
Required Work Experience:
- Experience with modern software technologies, including Node, TypeScript, React, and AWS.
- Prior experience working in a medical, diagnostics, or genomic information setting is required to effectively contribute to the development and maintenance of clinical interpretation systems.
- Familiarity with agile methodologies.
- Experience with User Experience.
- Strong communication skills.
- Test-driven development mindset and experience writing tests.
- Experience working in a regulated healthcare environment.
Preferred Work Experience:
- Experience with technologies such as SQL, PHP, Go, Python or Angular.
- Understanding of best practices for transitioning legacy systems.
- Familiarity with CDK and/or terraform.
- Familiarity with CI/CD and/or GitHub actions.
- Experience with containerized applications.
Physical and Mental Requirements:
- This role is required to collaborate with teams in US, EU and Asia, and at least 2 hour overlap during their business hours is expected.
Knowledge:
- Proficiency in full stack development, including front-end, back-end, and databases.
- Strong problem-solving abilities and a commitment to continuous learning.
Skills:
- Excellent collaboration and communication skills.
- Adaptability to new tools and technologies.
People Leader Responsibility:
- May include oversight of contractors.
Work Environment:
- Desk-Based Work: Prolonged periods of sitting or standing at a desk and working on a computer (typically 8 hours per day).
- Visual Acuity: Frequent and close visual concentration on computer screens, complex data visualizations, and extensive code repositories.
- Remote Workspace: Requirement to maintain a dedicated, professional, and secure home office environment free from distractions.
- Connectivity: Continuous access to a high-speed, secure, and reliable internet connection suitable for high-bandwidth virtual collaboration, video conferencing, and remote cloud infrastructure management.
- Analytical Thinking: High capacity for sustained cognitive focus, logical reasoning, and complex, scientific problem-solving.
- Effective Virtual Collaboration: Strong verbal and written communication skills to effectively collaborate, build relationships, and align with remote and cross-functional team members.
- Adaptability & Prioritization: Ability to self-manage, prioritize multiple competing tasks, and adapt to changing technical requirements or project scopes in a dynamic environment.
- Attention to Detail: Meticulous attention to code quality, security protocols, and data integrity, which is critical for clinical-grade validation.
Travel Required
English Required
Education:
- Bachelor’s degree in computer science, Engineering, or equivalent experience. (Required)
- Master’s degree in computer science, Engineering, or related field. (Preferred)
Preferred Technical Training or Professional Licensing:
- Certifications in cloud platforms (AWS).
- Projects available in GitLab/GitHub for review.
- Training in agile methodologies.
See all 67+ H-1B Visa Senior Bioinformatics Scientist Jobs
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Get Access To All JobsTips for Finding H-1B Visa Sponsorship as a Senior Bioinformatics Scientist
Align your degree to the role
USCIS scrutinizes specialty occupation claims when your degree field doesn't directly match the job. A degree in bioinformatics, computational biology, or biostatistics maps cleanly. A general biology or CS degree may require a detailed credentials evaluation to satisfy the direct-relationship requirement.
Check LCA filings by SOC code
Bioinformatics scientist roles file under SOC 19-1029 or 15-2099 depending on the employer's framing. Pull DOL LCA disclosure data filtered by those codes to find which biotech, pharma, and research institutions have active H-1B filing histories before sending applications.
Target employers with cap-exempt status
Universities, nonprofit research institutes, and government-affiliated labs are cap-exempt H-1B employers, meaning you can file any time of year without entering the lottery. Many senior bioinformatics roles exist at NIH-funded institutions and academic medical centers where this exemption applies.
Use Migrate Mate to filter verified sponsors
Pull up the Senior Bioinformatics Scientist listings on Migrate Mate and filter by employers with confirmed H-1B LCA filing history. That narrows your list to organizations that have already navigated the process for roles at this level, saving you outreach to non-sponsors.
Request prevailing wage documentation early
Before the I-129 is filed, your employer must certify the offered wage meets DOL prevailing wage for your location and experience level. Use the OFLC Wage Search to verify Level III or IV wages for your job site ZIP code so you can flag discrepancies before the LCA is submitted.
Negotiate H-1B filing costs into your offer
USCIS prohibits employers from passing mandatory I-129 filing fees to H-1B workers. Premium processing, however, is negotiable. If your start date is time-sensitive, confirm in writing whether the employer will cover premium processing before you accept the offer.
H-1B Visa Senior Bioinformatics Scientist: Frequently Asked Questions
Does a Senior Bioinformatics Scientist role qualify as an H-1B specialty occupation?
Yes. Senior Bioinformatics Scientist positions require at least a bachelor's degree in bioinformatics, computational biology, biostatistics, or a directly related field, which satisfies the USCIS specialty occupation definition. Roles involving genomic pipeline development, statistical modeling, or algorithm design for biological data have consistently met this standard. If your employer describes the role broadly, a strong job duties letter from a supervisor strengthens the petition.
Which employers regularly sponsor H-1B visas for bioinformatics roles?
Biotech companies, pharmaceutical research divisions, academic medical centers, and government-affiliated research institutions are the most consistent H-1B sponsors for bioinformatics positions. Cap-exempt employers like universities and NIH-funded nonprofits can file outside the annual lottery. You can browse verified H-1B-sponsoring employers hiring for this role on Migrate Mate, filtered by LCA filing history.
What happens to my H-1B status if my bioinformatics project ends and I'm laid off?
You have a 60-day grace period after involuntary termination to find a new employer, file a change of status, or depart the U.S. Your new employer must file an H-1B transfer petition before that window closes. If you're working at a large pharma or biotech with a track record of layoffs, negotiate a severance clause that keeps you on payroll through the grace period while you transition.
Can my employer file my H-1B as a concurrent position if I already hold H-1B status elsewhere?
Yes. H-1B holders can work concurrently for multiple employers as long as each employer files a separate I-129 petition. This is relevant for senior bioinformatics scientists who consult for biotech startups while employed full-time at a research institution. Each employer must independently satisfy prevailing wage and specialty occupation requirements. USCIS reviews each petition on its own merits.
Does my SOC code affect my H-1B prevailing wage determination?
Directly. Employers filing LCAs for bioinformatics roles may use SOC 19-1029 (Biological Scientists) or 15-2099 (Mathematical Science Occupations) depending on how they define the role's primary function. The SOC code determines which wage level USCIS and DOL apply. A mismatched code can expose the petition to a wage-related Request for Evidence. Cross-check the SOC your employer intends to use against the O*NET occupation profile before the LCA is certified.