Mid Level High School Biology Teacher Jobs
Mid level high school biology teacher jobs go to educators ready to own curriculum design, guide student-led investigations, and shape instructional decisions with limited administrative oversight. Roles run predominantly on-site across Biotechnology & Pharmaceuticals, Science & Research, and Healthcare & Medical Services, with employers like Eli Lilly, Genentech, and dsm-firmenich hiring at this level now.
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Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicleâ„¢ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Advances Denali’s oligonucleotide therapeutic pipeline by generating the in vivo and ex vivo evidence that guides candidate selection. Applies animal models, molecular and cellular assays, and pharmacokinetic and pharmacodynamic (PK/PD) studies to validate targets, identify biomarkers, and inform therapeutic development. Partners with Preclinical Translational Sciences, Developmental Sciences, Safety, and drug metabolism and pharmacokinetics (DMPK) scientists to move candidates through preclinical development. Delivers well-documented results that inform central nervous system (CNS) drug delivery and disease research decisions.
Key Accountabilities/Core Job Responsibilities:
- Design and execute in vivo and ex vivo studies that inform candidate progression, PK/PD modeling, and biomarker strategies
- Generate PK/PD data in preclinical models in partnership with Safety and DMPK scientists
- Perform molecular and biochemical assays, including RNA extraction, quantitative PCR, tissue sectioning, immunofluorescence, microscopy, and ELISAs
- Troubleshoot technical issues to keep experiments on schedule
- Evaluate oligonucleotide therapeutic candidates in CNS tissue-based models
- Analyze and interpret experimental data and report quantitative results
- Document experiments completely in electronic lab notebooks
- Present experimental designs and study results to cross-functional teams and collaborators
- Apply emerging scientific literature and technologies in CNS drug delivery and disease research to study design
Qualifications/Skills:
- Typically requires a PhD in Neuroscience, Cell Biology, Pharmacology, or a related scientific field; or a Master’s degree and 3+ years of relevant experience in academia or pharmaceutical discovery/translational research
- Hands-on proficiency in wet lab techniques (for example RNA extraction, quantitative PCR, tissue sectioning, immunofluorescence, microscopy, and ELISAs)
- Experience with in vivo models and CNS tissue-based studies
- Strong scientific reasoning in experimental design and data analysis
- Strong verbal and written communication skills, with the ability to work independently, prioritize tasks, and adapt in a fast-paced research environment
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicleâ„¢ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
Advances Denali’s oligonucleotide therapeutic pipeline by generating the in vivo and ex vivo evidence that guides candidate selection. Applies animal models, molecular and cellular assays, and pharmacokinetic and pharmacodynamic (PK/PD) studies to validate targets, identify biomarkers, and inform therapeutic development. Partners with Preclinical Translational Sciences, Developmental Sciences, Safety, and drug metabolism and pharmacokinetics (DMPK) scientists to move candidates through preclinical development. Delivers well-documented results that inform central nervous system (CNS) drug delivery and disease research decisions.
Key Accountabilities/Core Job Responsibilities:
- Design and execute in vivo and ex vivo studies that inform candidate progression, PK/PD modeling, and biomarker strategies
- Generate PK/PD data in preclinical models in partnership with Safety and DMPK scientists
- Perform molecular and biochemical assays, including RNA extraction, quantitative PCR, tissue sectioning, immunofluorescence, microscopy, and ELISAs
- Troubleshoot technical issues to keep experiments on schedule
- Evaluate oligonucleotide therapeutic candidates in CNS tissue-based models
- Analyze and interpret experimental data and report quantitative results
- Document experiments completely in electronic lab notebooks
- Present experimental designs and study results to cross-functional teams and collaborators
- Apply emerging scientific literature and technologies in CNS drug delivery and disease research to study design
Qualifications/Skills:
- Typically requires a PhD in Neuroscience, Cell Biology, Pharmacology, or a related scientific field; or a Master’s degree and 3+ years of relevant experience in academia or pharmaceutical discovery/translational research
- Hands-on proficiency in wet lab techniques (for example RNA extraction, quantitative PCR, tissue sectioning, immunofluorescence, microscopy, and ELISAs)
- Experience with in vivo models and CNS tissue-based studies
- Strong scientific reasoning in experimental design and data analysis
- Strong verbal and written communication skills, with the ability to work independently, prioritize tasks, and adapt in a fast-paced research environment
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
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Mid Level High School Biology Teacher Jobs: Frequently Asked Questions
How do I get a mid level high school biology teacher job?
Position your application around concrete outcomes you have driven, such as improved student assessment scores, curriculum units you designed independently, or lab programs you built from the ground up. Highlight your ability to differentiate instruction, manage a full course load without close supervision, and contribute beyond the classroom through extracurriculars or department committees. A strong letter of recommendation from a department head or principal carries significant weight at this level.
Which companies hire mid level high school biology teachers?
Companies hiring mid level high school biology teachers right now include Eli Lilly, Genentech, and dsm-firmenich, based on current listings on Migrate Mate as of November 2026. Hiring at this level comes primarily from public school districts, private and charter school networks, and specialized STEM-focused secondary schools seeking educators who can work independently and elevate departmental instruction.
Are there remote mid level high school biology teacher jobs?
Yes, though options are more limited than in many other fields given the hands-on nature of biology lab instruction. About 14% of mid level high school biology teacher openings are remote or hybrid as of November 2026, and these roles tend to be with virtual charter schools, online learning platforms, or hybrid academies that blend asynchronous coursework with periodic in-person lab sessions.
How do I move up to a mid level high school biology teacher role?
Reaching the mid level means demonstrating that you can take full ownership of your classroom without close mentorship. Focus on deepening your content expertise in areas like genetics, ecology, or AP Biology, and build a record of measurable student outcomes. Volunteering to lead curriculum mapping, mentor student teachers, or coordinate department projects signals the kind of independent judgment schools look for when moving educators into mid level positions.
Which industries hire the most mid level high school biology teachers?
Mid Level high school biology teacher roles concentrate in Biotechnology & Pharmaceuticals, Science & Research, and Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because demand for experienced, independently operating science educators is consistent in both publicly funded districts and privately managed school networks expanding their STEM course offerings.