IT Manager Jobs in Houston, TX
IT Manager jobs in Houston are in strong demand across energy, healthcare, and petrochemical sectors, with the heaviest concentration of openings in the Energy Corridor, Greenway Plaza, and the Texas Medical Center. Employers actively hiring right now include Deloitte, PwC, and Bayer. See the openings below and apply to the ones that match your experience.
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IT Solution Architect
Location: Houston, TX.
The actual location of this job is in Houston, US. Relocation assistance is available for eligible candidates and their families, if needed.
Today, Lonza is a global leader in life sciences operating across five continents.
You will play a key role connecting Lonza, our customers, and patients. As a Principal Program Manager, you will ensure programs are delivered on time, within scope, and to the highest quality standards.
The IT Solution Architect plays a critical role in driving the IT architecture within the A2D stream, that integrate with S/4HANA to optimize business processes.
What you will get:
- An agile career and dynamic working culture.
- An inclusive and ethical workplace.
- Compensation programs that recognize high performance.
- Medical, dental, and vision insurance.
- Access to Lonza’s global benefits program.
What you will do:
System Design and Architecture
- Act as a subject matter expert, expert for the future SAP solution in revenue and cost controlling, assuring compliance with the OneLonza strategy and scalability.
- Collaborate with business teams to understand business processes and challenges, providing thought leadership on how SAP solutions can optimize these processes in the context of a business transformation.
- Drive the adoption of SAP best practices and industry standards within the organization’s transformation journey.
Integration and Process Design
- Lead the design and implementation of integrated solutions within the SAP landscape, ensuring seamless data flow and user experience.
- Define and document detailed process flows, functional specifications, and interface requirements the stream related processes.
Stakeholder Management
- Collaborate with other GPOs, business users and stream members to understand requirements and review business flows with aim of optimization and innovation.
- Keep informed of business-critical project outside Nexus S4 to capture business value gain in the new solution and avoiding possible conflicts.
- Review and verify prototypes with site stakeholders and enabling functions, identifying area of improvement.
- Translate business requirements into system solutions being able to effectively communicate with both business and IT stakeholders.
Customization & Configuration
- Oversee SAP configuration, ensuring the solutions are tailored to meet business requirements.
- Guide the technical team in the customization and development of enhancements and custom reports.
Compliance and Security
- Ensure that S/4HANA adhere to compliance standards (GMP) and security protocols, mitigating financial and operational risks.
- Support interim phases to guarantee business continuity.
Change Management & Training
- Support change management efforts by preparing the organization for system and process changes.
- Provide leadership in developing training materials and delivering end-user training.
What we are looking for:
- Master’s Degree in IT architecture, with a strong focus for related stream systems with ERP platforms, or related field.
- 10+ years IT architecture, with a strong focus on stream related processes systems with ERP platforms.
- Proven experience in at least one full-cycle SAP implementation, with a focus on the respective workstream processes.
- Strong understanding of Stream related processes.
- In-depth knowledge of SAP S/4HANA, particularly in the areas of the stream related processes.
- Experience with process mapping, data migration, and system configuration within SAP environments.
- Proficiency in project management tools and methodologies (e.g., Agile, Waterfall).
- Excellent communication, leadership, and interpersonal skills, with the ability to engage and influence stakeholders at all levels.
- Strong analytical and problem-solving skills, with a focus on delivering high-quality outcomes.
- Will require travel depending on project needs: 1st year min. 5-6 times for a duration of 2-3 weeks, less in 2nd year but still regularly.
- Ability to work in a dynamic environment with tight deadlines.
About Lonza
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.
IT Solution Architect
Location: Houston, TX.
The actual location of this job is in Houston, US. Relocation assistance is available for eligible candidates and their families, if needed.
Today, Lonza is a global leader in life sciences operating across five continents.
You will play a key role connecting Lonza, our customers, and patients. As a Principal Program Manager, you will ensure programs are delivered on time, within scope, and to the highest quality standards.
The IT Solution Architect plays a critical role in driving the IT architecture within the A2D stream, that integrate with S/4HANA to optimize business processes.
What you will get:
- An agile career and dynamic working culture.
- An inclusive and ethical workplace.
- Compensation programs that recognize high performance.
- Medical, dental, and vision insurance.
- Access to Lonza’s global benefits program.
What you will do:
System Design and Architecture
- Act as a subject matter expert, expert for the future SAP solution in revenue and cost controlling, assuring compliance with the OneLonza strategy and scalability.
- Collaborate with business teams to understand business processes and challenges, providing thought leadership on how SAP solutions can optimize these processes in the context of a business transformation.
- Drive the adoption of SAP best practices and industry standards within the organization’s transformation journey.
Integration and Process Design
- Lead the design and implementation of integrated solutions within the SAP landscape, ensuring seamless data flow and user experience.
- Define and document detailed process flows, functional specifications, and interface requirements the stream related processes.
Stakeholder Management
- Collaborate with other GPOs, business users and stream members to understand requirements and review business flows with aim of optimization and innovation.
- Keep informed of business-critical project outside Nexus S4 to capture business value gain in the new solution and avoiding possible conflicts.
- Review and verify prototypes with site stakeholders and enabling functions, identifying area of improvement.
- Translate business requirements into system solutions being able to effectively communicate with both business and IT stakeholders.
Customization & Configuration
- Oversee SAP configuration, ensuring the solutions are tailored to meet business requirements.
- Guide the technical team in the customization and development of enhancements and custom reports.
Compliance and Security
- Ensure that S/4HANA adhere to compliance standards (GMP) and security protocols, mitigating financial and operational risks.
- Support interim phases to guarantee business continuity.
Change Management & Training
- Support change management efforts by preparing the organization for system and process changes.
- Provide leadership in developing training materials and delivering end-user training.
What we are looking for:
- Master’s Degree in IT architecture, with a strong focus for related stream systems with ERP platforms, or related field.
- 10+ years IT architecture, with a strong focus on stream related processes systems with ERP platforms.
- Proven experience in at least one full-cycle SAP implementation, with a focus on the respective workstream processes.
- Strong understanding of Stream related processes.
- In-depth knowledge of SAP S/4HANA, particularly in the areas of the stream related processes.
- Experience with process mapping, data migration, and system configuration within SAP environments.
- Proficiency in project management tools and methodologies (e.g., Agile, Waterfall).
- Excellent communication, leadership, and interpersonal skills, with the ability to engage and influence stakeholders at all levels.
- Strong analytical and problem-solving skills, with a focus on delivering high-quality outcomes.
- Will require travel depending on project needs: 1st year min. 5-6 times for a duration of 2-3 weeks, less in 2nd year but still regularly.
- Ability to work in a dynamic environment with tight deadlines.
About Lonza
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.
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Find IT Manager JobsIT Manager Job Market in Houston
Who's Hiring
- Deloitte43
- PwC7
- Bayer5
- Accenture4
- Sargent & Lundy4
Top Industries Hiring
- Consulting & Professional Services86
- Accounting & Auditing51
- Investment & Asset Management44
- Technology & Software25
- Energy22
IT Manager Jobs in Houston: Frequently Asked Questions
How do I get a it manager job in Houston?
Focus your search on Houston's dominant sectors: energy, healthcare systems, and petrochemical operations, where IT leadership demand is consistently high. The Energy Corridor and Texas Medical Center are the two densest hiring hubs. Candidates who can demonstrate experience managing infrastructure for regulated industries, particularly oil and gas or clinical environments, have a clear edge over generalists in this market.
Which companies hire it managers in Houston?
Companies currently hiring it managers in Houston include Deloitte, PwC, and Bayer, per current listings on Migrate Mate as of June 2026. Houston's employer mix skews toward large energy operators, integrated health networks, and engineering and construction firms, all of which maintain sizable internal IT departments requiring dedicated management.
Are there remote it manager jobs in Houston?
Yes, though it manager roles are less remote-friendly than individual contributor tech positions because they typically require on-site presence to oversee infrastructure, vendors, and teams. About 24% of it manager openings tied to Houston are remote or hybrid as of June 2026, with hybrid arrangements most common at professional services and corporate headquarters rather than field-heavy energy or hospital operations.
How can I get a it manager job in Houston with little or no experience?
The most realistic entry path in Houston is moving up from a senior systems administrator or IT team lead role within the energy or healthcare sectors, where internal promotions are common and employers value operational continuity. Houston's large hospital networks and mid-size oilfield services companies regularly develop technical staff into management, making them more accessible than major corporate headquarters. Earning a PMP or ITIL certification before applying strengthens candidacy noticeably in this market.
Which industries hire the most it managers in Houston?
Most it manager openings in Houston sit in Consulting & Professional Services, Accounting & Auditing, and Investment & Asset Management, per current listings on Migrate Mate as of June 2026. Houston's concentration of integrated energy companies, petrochemical operators, and one of the country's largest medical complexes creates sustained, recurring demand for IT leadership that outpaces most comparably sized U.S. cities.
See All 277+ IT Manager Jobs in Houston
Find roles in Houston that match your experience and apply in just a few clicks.
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