IT Security Engineer Jobs in California
IT Security Engineer jobs in California are among the most active in the country, with strong demand from technology companies, defense contractors, financial institutions, and healthcare systems at levels from entry-level analyst to senior architect. San Jose, San Francisco, and Los Angeles anchor most of the hiring, with major employers including Lockheed Martin, Kaiser Permanente, and Wells Fargo maintaining large security teams across the state. The most sought-after specialties in California listings are cloud security, zero-trust architecture, and security operations center work. Find a role that fits below and apply directly.
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Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.
Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.
We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.
THE OPPORTUNITY
Vir Biotechnology is seeking a Senior Infrastructure & IT Security Engineer (Temp Staff) to join our IT team. This is a senior, hands-on individual contributor role that combines IT infrastructure engineering and security operations. In this role, you will help maintain, secure, troubleshoot, and continuously improve the technology that enables Vir Bio's business and scientific mission, spanning endpoints, identity platforms, cloud services, servers, networking, virtualization, and security tools.
The successful candidate is an execution-focused technology professional who enjoys solving complex technical challenges, takes ownership from problem identification through resolution, and balances security, reliability, and user experience. You are a collaborative partner who can navigate ambiguity, communicate clearly, document thoroughly, and identify opportunities to strengthen systems, automate processes, and improve operational excellence.
This role is located in our San Francisco headquarters with an expectation of 4 days per week in office.
WHAT YOU'LL DO
What You'll Do
Infrastructure Engineering & Operations
- Implement, maintain, and enhance infrastructure across cloud, on-premises, and hybrid environments
- Administer and support Windows, macOS, Windows Server, and Linux environments, including patching, monitoring, troubleshooting, and lifecycle management
- Support AWS infrastructure, enterprise networking, virtualization platforms, and remote access technologies
- Manage identity, access management, endpoint technologies, and core infrastructure services
- Troubleshoot complex issues spanning endpoints, applications, cloud services, networks, and third-party systems
- Develop automation and scripting solutions to improve efficiency, consistency, and operational visibility
- Execute infrastructure changes in accordance with established security, architecture, and change management standards
- Maintain technical documentation, runbooks, implementation procedures, and recovery plans
IT Security Operations
- Monitor, investigate, and respond to security events, alerts, vulnerabilities, and incidents across the technology environment
- Support endpoint protection, identity security, privileged access, vulnerability management, logging, and other security technologies
- Partner with stakeholders to identify, assess, and remediate security risks and configuration gaps
- Support identity and access platforms, including Microsoft Entra ID, Active Directory, and Okta
- Participate in incident response activities, including investigation, containment, remediation, recovery, and documentation
- Assist with audit, compliance, and security review activities by collecting technical evidence and validating controls
- Contribute to the continuous improvement of security monitoring, processes, documentation, and operational procedures
- Help strengthen Vir's security posture by identifying opportunities to improve controls, visibility, and response capabilities
Across both areas, you will serve as a senior technical resource, partnering closely with IT, Security, business stakeholders, managed service providers, and vendors to resolve complex issues, implement technical solutions, and drive operational excellence through clear communication, documentation, and continuous improvement.
WHO YOU ARE AND WHAT YOU BRING
- Extensive hands-on experience in infrastructure engineering, systems administration, cybersecurity, or a related enterprise IT role
- Strong experience supporting and securing Windows, macOS, Windows Server, and Linux environments
- Experience with cloud technologies, preferably AWS, along with enterprise networking, identity and access management, and endpoint management solutions
- Hands-on experience investigating security events, responding to incidents, and remediating vulnerabilities and operational risks
- Experience supporting enterprise security technologies, including endpoint protection, privileged access, firewalls, and remote access solutions
- Strong scripting and automation skills using PowerShell, Python, or similar technologies
- Demonstrated ability to troubleshoot complex issues across multiple systems and stakeholders
- Strong communication and documentation skills, with the ability to clearly explain technical risks and solutions to both technical and non-technical audiences
- Ability to work independently, manage competing priorities, and drive issues through resolution
- Experience in a regulated industry (biotechnology, pharmaceutical, healthcare, or similar), familiarity with security frameworks such as NIST or CIS Controls, and relevant cloud, infrastructure, networking, or security certifications are preferred
WHO WE ARE AND WHAT WE OFFER
The expected hourly range for this position is $65.00 to $90.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.
Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.
All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics.
This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.
Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.
For hires based in the United States, Vir Biotechnology, participates in E-Verify.
Candidate Privacy Notice
Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.
Vir Biotechnology has exclusive rights to the universal PRO-XTEN® masking platform for oncology and infectious disease. PRO-XTEN® is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company.
We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best.
THE OPPORTUNITY
Vir Biotechnology is seeking a Senior Infrastructure & IT Security Engineer (Temp Staff) to join our IT team. This is a senior, hands-on individual contributor role that combines IT infrastructure engineering and security operations. In this role, you will help maintain, secure, troubleshoot, and continuously improve the technology that enables Vir Bio's business and scientific mission, spanning endpoints, identity platforms, cloud services, servers, networking, virtualization, and security tools.
The successful candidate is an execution-focused technology professional who enjoys solving complex technical challenges, takes ownership from problem identification through resolution, and balances security, reliability, and user experience. You are a collaborative partner who can navigate ambiguity, communicate clearly, document thoroughly, and identify opportunities to strengthen systems, automate processes, and improve operational excellence.
This role is located in our San Francisco headquarters with an expectation of 4 days per week in office.
WHAT YOU'LL DO
What You'll Do
Infrastructure Engineering & Operations
- Implement, maintain, and enhance infrastructure across cloud, on-premises, and hybrid environments
- Administer and support Windows, macOS, Windows Server, and Linux environments, including patching, monitoring, troubleshooting, and lifecycle management
- Support AWS infrastructure, enterprise networking, virtualization platforms, and remote access technologies
- Manage identity, access management, endpoint technologies, and core infrastructure services
- Troubleshoot complex issues spanning endpoints, applications, cloud services, networks, and third-party systems
- Develop automation and scripting solutions to improve efficiency, consistency, and operational visibility
- Execute infrastructure changes in accordance with established security, architecture, and change management standards
- Maintain technical documentation, runbooks, implementation procedures, and recovery plans
IT Security Operations
- Monitor, investigate, and respond to security events, alerts, vulnerabilities, and incidents across the technology environment
- Support endpoint protection, identity security, privileged access, vulnerability management, logging, and other security technologies
- Partner with stakeholders to identify, assess, and remediate security risks and configuration gaps
- Support identity and access platforms, including Microsoft Entra ID, Active Directory, and Okta
- Participate in incident response activities, including investigation, containment, remediation, recovery, and documentation
- Assist with audit, compliance, and security review activities by collecting technical evidence and validating controls
- Contribute to the continuous improvement of security monitoring, processes, documentation, and operational procedures
- Help strengthen Vir's security posture by identifying opportunities to improve controls, visibility, and response capabilities
Across both areas, you will serve as a senior technical resource, partnering closely with IT, Security, business stakeholders, managed service providers, and vendors to resolve complex issues, implement technical solutions, and drive operational excellence through clear communication, documentation, and continuous improvement.
WHO YOU ARE AND WHAT YOU BRING
- Extensive hands-on experience in infrastructure engineering, systems administration, cybersecurity, or a related enterprise IT role
- Strong experience supporting and securing Windows, macOS, Windows Server, and Linux environments
- Experience with cloud technologies, preferably AWS, along with enterprise networking, identity and access management, and endpoint management solutions
- Hands-on experience investigating security events, responding to incidents, and remediating vulnerabilities and operational risks
- Experience supporting enterprise security technologies, including endpoint protection, privileged access, firewalls, and remote access solutions
- Strong scripting and automation skills using PowerShell, Python, or similar technologies
- Demonstrated ability to troubleshoot complex issues across multiple systems and stakeholders
- Strong communication and documentation skills, with the ability to clearly explain technical risks and solutions to both technical and non-technical audiences
- Ability to work independently, manage competing priorities, and drive issues through resolution
- Experience in a regulated industry (biotechnology, pharmaceutical, healthcare, or similar), familiarity with security frameworks such as NIST or CIS Controls, and relevant cloud, infrastructure, networking, or security certifications are preferred
WHO WE ARE AND WHAT WE OFFER
The expected hourly range for this position is $65.00 to $90.00. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors.
Applicants must currently be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time.
All employment decisions at Vir Biotechnology are based on legitimate, non-discriminatory business requirements, job duties and individual qualifications. Employment decisions are made without regard to any legally protected characteristics.
This commitment extends to all management practices and decisions, including recruitment and hiring, compensation, appraisal systems, promotions, training and career development programs. Vir Biotechnology also strongly commits to providing employees with a work environment free of unlawful conduct or harassment.
Vir Biotechnology Human Resources leads recruitment and employment for Vir Biotechnology. Unsolicited resumes sent to the company from recruiters do not constitute any type of relationship between the recruiter and Vir Biotechnology and do not obligate us to pay fees should we hire from those resumes. We ask that external recruiters and/or agencies not contact or present candidates directly to our hiring manager or employees.
For hires based in the United States, Vir Biotechnology, participates in E-Verify.
Candidate Privacy Notice
See All 33 IT Security Engineer Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find IT Security Engineer JobsIT Security Engineer Jobs by City in California
Where California roles are concentrated, by current openings.
IT Security Engineer Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Technology & Software
- Science & Research
What California Employers Look For
The qualifications that appear most often in IT security engineer jobs across California.
- Bachelor's degree in computer science, information security, or a related technical field
- Industry certification such as CISSP, CISM, CEH, or CompTIA Security+ strongly preferred
- Hands-on experience with SIEM platforms, endpoint detection, and incident response tools
- Working knowledge of NIST, ISO 27001, and California Consumer Privacy Act compliance frameworks
- Experience securing cloud environments on AWS, Azure, or Google Cloud Platform
- Ability to obtain or maintain security clearance for defense and government contract roles
IT Security Engineer Jobs in California: Frequently Asked Questions
How do you become a it security engineer in California?
IT security engineer roles in California do not require a state-issued license, but employers consistently expect a bachelor's degree in computer science, cybersecurity, or information systems alongside recognized industry certifications such as CISSP, CISM, or CompTIA Security+. California's large defense and financial sectors often require candidates to complete a federal security clearance process. Building hands-on experience through internships, capture-the-flag competitions, or home lab projects strengthens applications considerably.
How much do IT security engineers make in California?
IT security engineers in California earn a median of about $138,570 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,070 for the lowest 10% to over $221,000 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire it security engineers in California?
Employers hiring it security engineers in California right now include GoFormz, University of California Berkeley, and FAR.AI, based on current listings on Migrate Mate as of September 2026. California's concentration of technology headquarters, defense primes, and large hospital systems means consistent openings appear across a wide range of industries rather than clustering in a single sector.
Which California cities have the most it security engineer jobs?
San Francisco, San Diego, and Berkeley post the most it security engineer openings in California. The San Jose and San Francisco concentration reflects the density of technology headquarters and cloud infrastructure firms in the Bay Area, while Los Angeles draws volume from entertainment studios, aerospace and defense contractors, and large financial services firms headquartered in the region.
Are there remote it security engineer jobs in California?
Yes, and more than most fields. About 36% of it security engineer openings tied to California are remote or hybrid as of September 2026, reflecting how much of the work centers on monitoring dashboards, writing policies, and reviewing logs rather than touching physical hardware. Roles tied to on-site infrastructure, data centers, or government facilities with classified networks remain in-person by requirement.
How can I get hired as a it security engineer in California with little or no experience?
The most realistic entry path is landing a security analyst or IT support role first, then moving laterally into security engineering. Large California technology companies and hospital systems including those in the UC Health network run structured associate and rotational programs that accept candidates without dedicated security experience. Earning CompTIA Security+ or completing a recognized cybersecurity bootcamp recognized by California community colleges signals commitment, and a documented home lab or capture-the-flag portfolio gives interviewers something concrete to evaluate.
Where can I find and apply to it security engineer jobs in California?
You can find and apply to it security engineer jobs in California on Migrate Mate, which lists current openings from employers hiring in the state. Find the roles that fit your experience and location, then apply directly through each listing.
See All 33 IT Security Engineer Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
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