Senior Level Laboratory Manager Jobs
Senior level laboratory manager jobs place experienced scientists and operations leaders in charge of laboratory strategy, quality systems, and the teams that keep complex research or production environments running. Roles skew heavily on-site, with employers across Healthcare & Medical Services and Education, including Atlantic Health, Tenet Healthcare, and Quest Diagnostics, hiring at this level now.
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See related jobsWHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you’ll discover a culture of teamwork, professionalism, and a rewarding career!
JOB SUMMARY
The Laboratory Information Systems (LIS) Manager is responsible for the strategic leadership, operational management, governance, implementation, and support of laboratory information systems that enable Clinical Pathology, Anatomic Pathology, Blood Bank, and related laboratory services. This leadership role ensures the effective delivery, optimization, and compliance of laboratory technology solutions that support high-quality patient care, operational excellence, and organizational objectives.
The Manager serves as the primary liaison between Information Resources (IR), Laboratory Services, Pathology Leadership, clinical and operational departments, executive stakeholders, and technology vendors. The role requires strong technical expertise, leadership skills, and the ability to manage complex initiatives in a highly regulated healthcare environment.
KEY RESPONSIBILITIES
- Provide strategic direction and operational oversight for all Laboratory Information Systems (LIS) and related applications.
- Lead the planning, implementation, optimization, and maintenance of laboratory technology solutions supporting Clinical Pathology, Anatomic Pathology, Blood Bank, and outreach laboratory operations.
- Establish and oversee governance processes, prioritization frameworks, and project portfolios related to LIS initiatives.
- Partner with laboratory leadership, pathologists, clinicians, and operational stakeholders to identify technology needs and implement effective solutions.
- Ensure system reliability, performance, availability, security, and scalability across laboratory applications.
- Direct and manage complex projects, including system upgrades, implementations, integrations, workflow enhancements, and regulatory initiatives.
- Oversee vendor relationships, contract performance, and service delivery to ensure organizational expectations are met.
- Ensure compliance with applicable regulatory and accreditation standards, including CAP, CLIA, FDA, HIPAA, and other healthcare requirements.
- Develop and maintain policies, procedures, and standards related to laboratory information systems and data management.
- Lead risk assessment, change management, testing, validation, and issue resolution processes for laboratory technology systems.
- Monitor key performance indicators and drive continuous improvement initiatives to enhance operational efficiency and user satisfaction.
- Manage, mentor, and develop LIS team members while fostering a culture of collaboration, accountability, and innovation.
BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare - no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
EXPERIENCE AND EDUCATION
Required
Education
High School Diploma or equivalent or
Bachelor’s Degree with major coursework in computer science, math, information systems, or other related field
Experience
8 years progressively responsible and applicable information technology experience with High School Diploma including 2 years in supervisory or managerial role or
6 years progressively responsible information technology experience with Bachelor’s Degree including 2 years in supervisory or managerial role
JOB DUTIES
- Manages Information Resources section, such as Network Services, Software Systems Programming, Computer Training, etc. following university policies and procedures and using effective management, communication, and customer service skills to develop and ensure effective program.
- Develops, revises, recommends, and interprets policies and procedures for section to ensure all applicable laws and governmental guidelines are followed and that employees are treated in equitable manner.
- Coordinates various projects and programs for section ensuring all tasks are completed by established deadlines and to ensure that quality customer service is provided for faculty and staff.
- Assists campus departments in assessing technical requirements that meet needs of their operation.
- Completes work specific to assigned section using appropriate technologies and communication skills.
- Supervises group of professional and/or administrative support employees.
- Performs other duties as assigned.
SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. To the extent this position requires the holder to research, work on, or have access to critical infrastructure as defined in Section 117.001(2) of the Texas Business and Commerce Code, the ability to maintain the security or integrity of the critical infrastructure is a minimum qualification to be hired and to continue to be employed in the position.
EEO
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
WHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you’ll discover a culture of teamwork, professionalism, and a rewarding career!
JOB SUMMARY
The Laboratory Information Systems (LIS) Manager is responsible for the strategic leadership, operational management, governance, implementation, and support of laboratory information systems that enable Clinical Pathology, Anatomic Pathology, Blood Bank, and related laboratory services. This leadership role ensures the effective delivery, optimization, and compliance of laboratory technology solutions that support high-quality patient care, operational excellence, and organizational objectives.
The Manager serves as the primary liaison between Information Resources (IR), Laboratory Services, Pathology Leadership, clinical and operational departments, executive stakeholders, and technology vendors. The role requires strong technical expertise, leadership skills, and the ability to manage complex initiatives in a highly regulated healthcare environment.
KEY RESPONSIBILITIES
- Provide strategic direction and operational oversight for all Laboratory Information Systems (LIS) and related applications.
- Lead the planning, implementation, optimization, and maintenance of laboratory technology solutions supporting Clinical Pathology, Anatomic Pathology, Blood Bank, and outreach laboratory operations.
- Establish and oversee governance processes, prioritization frameworks, and project portfolios related to LIS initiatives.
- Partner with laboratory leadership, pathologists, clinicians, and operational stakeholders to identify technology needs and implement effective solutions.
- Ensure system reliability, performance, availability, security, and scalability across laboratory applications.
- Direct and manage complex projects, including system upgrades, implementations, integrations, workflow enhancements, and regulatory initiatives.
- Oversee vendor relationships, contract performance, and service delivery to ensure organizational expectations are met.
- Ensure compliance with applicable regulatory and accreditation standards, including CAP, CLIA, FDA, HIPAA, and other healthcare requirements.
- Develop and maintain policies, procedures, and standards related to laboratory information systems and data management.
- Lead risk assessment, change management, testing, validation, and issue resolution processes for laboratory technology systems.
- Monitor key performance indicators and drive continuous improvement initiatives to enhance operational efficiency and user satisfaction.
- Manage, mentor, and develop LIS team members while fostering a culture of collaboration, accountability, and innovation.
BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare - no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
EXPERIENCE AND EDUCATION
Required
Education
High School Diploma or equivalent or
Bachelor’s Degree with major coursework in computer science, math, information systems, or other related field
Experience
8 years progressively responsible and applicable information technology experience with High School Diploma including 2 years in supervisory or managerial role or
6 years progressively responsible information technology experience with Bachelor’s Degree including 2 years in supervisory or managerial role
JOB DUTIES
- Manages Information Resources section, such as Network Services, Software Systems Programming, Computer Training, etc. following university policies and procedures and using effective management, communication, and customer service skills to develop and ensure effective program.
- Develops, revises, recommends, and interprets policies and procedures for section to ensure all applicable laws and governmental guidelines are followed and that employees are treated in equitable manner.
- Coordinates various projects and programs for section ensuring all tasks are completed by established deadlines and to ensure that quality customer service is provided for faculty and staff.
- Assists campus departments in assessing technical requirements that meet needs of their operation.
- Completes work specific to assigned section using appropriate technologies and communication skills.
- Supervises group of professional and/or administrative support employees.
- Performs other duties as assigned.
SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. To the extent this position requires the holder to research, work on, or have access to critical infrastructure as defined in Section 117.001(2) of the Texas Business and Commerce Code, the ability to maintain the security or integrity of the critical infrastructure is a minimum qualification to be hired and to continue to be employed in the position.
EEO
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
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Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Education
Senior Level Laboratory Manager Jobs: Frequently Asked Questions
How do I get a senior level laboratory manager job?
Employers at this level look for candidates who have owned outcomes, not just executed tasks. Demonstrated success leading cross-functional teams, managing regulatory compliance, and driving process improvements are strong differentiators. Highlight specific instances where your decisions shaped laboratory performance, reduced costs, or accelerated throughput. Advanced credentials in a relevant discipline and experience mentoring junior staff reinforce your readiness for senior ownership.
Which companies hire senior level laboratory managers?
Companies hiring senior level laboratory managers right now include Atlantic Health, Tenet Healthcare, and Quest Diagnostics, based on current listings on Migrate Mate as of September 2026. Hiring at this level tends to concentrate among large pharmaceutical, biotech, medical device, and contract research organizations that maintain complex, regulated laboratory environments requiring experienced leadership.
Are there remote senior level laboratory manager jobs?
Yes, though most laboratory manager roles require an on-site presence due to the hands-on nature of the work. About 0% of senior level laboratory manager openings are remote or hybrid as of September 2026, and these positions typically involve oversight, quality systems, or regulatory functions that can be handled off-site rather than direct bench supervision.
What makes a laboratory manager role senior level?
Senior level laboratory manager roles carry broader scope and deeper accountability than mid-level positions. Expectations include setting operational direction, owning compliance and quality outcomes, leading multi-person teams, managing capital equipment decisions, and mentoring junior and mid-level staff. These roles often interface directly with executive leadership, clients, or regulatory bodies and require the experience to navigate complex technical and organizational challenges independently.
Which industries hire the most senior level laboratory managers?
Senior Level laboratory manager roles concentrate in Healthcare & Medical Services and Education, based on current listings on Migrate Mate as of September 2026. These sectors drive demand because their operations depend on rigorous quality control, regulatory compliance, and continuous process improvement, all of which require experienced laboratory leadership to execute reliably at scale.