Manufacturing Process Engineer Jobs in Maryland
Manufacturing Process Engineer jobs in Maryland concentrate in aerospace and defense manufacturing, biotechnology production, and advanced electronics, with demand across entry-level to senior roles in one of the mid-Atlantic's most active engineering markets. The heaviest hiring is in and around Baltimore, the Washington D.C. suburbs of Montgomery and Prince George's counties, and the Eastern Shore corridor, where established employers like Lockheed Martin, Northrop Grumman, and McCormick and Company maintain significant manufacturing operations. The most in-demand specialties are lean manufacturing, process validation, and quality systems engineering. Scan the live roles below and apply to whichever ones fit.
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See related jobsSenior Process Engineer, Manufacturing Sciences & Technology, Cell Therapy:
Location: AstraZeneca, Rockville, MD
Travel: Up to 15% domestic and international travel required
Position Summary
We are seeking an experienced Senior Process Engineer to join our Manufacturing Sciences & Technology (MS&T) function as a member of the site-based MS&T team at AstraZeneca’s Rockville, MD cell therapy manufacturing facility.
This position focuses on ensuring robust, compliant, and cost-effective manufacturing of clinical and commercial cell therapy products.
Responsibilities include leading on-the-floor / hands-on technical support, developing technical instructions, procedures, and operator training content, performing data analysis and process performance trending, leading complex deviation investigations, driving implementation of CAPAs and continuous improvement through change controls, and giving to validation and regulatory work. These responsibilities will be exercised through the scope of supporting technology transfers, clinical manufacturing, site readiness, process validation/PPQ, commercial manufacture readiness, and product lifecycle management activities.
The ideal candidate brings hands-on experience with cell therapy unit operations through previous experience in process development and/or manufacturing, as well as expertise in technology transfer. Experience with process validation and commercialization activities is desired. This position will report to Director, MS&T, Cell Therapy Development and Operations.
Key Responsibilities
Site manufacturing support
- Process Execution Support: Provide day-to-day technical support for cell therapy manufacturing, including on-the-floor support for critical campaigns (including occasional off-shift support where required)
- Operations Support: Represent Site MS&T function at site operational tier meetings, providing collaborative inputs that drive site activities
- Data trending and analysis: Maintain manufacturing data tracking system and control charts, perform trend analyses, identify signals, and drive timely signal-to-action with clear documentation and multi-functional alignment.
- Process performance monitoring: Conduct batch record review, deviation assessment, and data trending to ensure robustness of cell therapy manufacturing processes.
- Deviation/CAPA Support: Lead or co-lead technical investigations for deviations and process excursions, perform root cause analysis, develop and implement CAPAs with appropriate data.
- Continuous improvements: Identify, justify, and implement continuous improvements by shepherding changes through multi-functional change controls with appropriate risk assessments and comparability.
- Raw materials: Support qualification of critical materials (e.g., cytokines, viral vector, single-use assemblies) and assess impact of raw material changes, and supply to second-source strategies
- Automation: Partner with automation/digital manufacturing teams to implement electronic batch record improvements
- Documentation & GMP Compliance: Author and revise batch records, SOPs, and technical reports; protocols, summary reports, ensure alignment to cGMP/ATMP requirements and data integrity principles (ALCOA+).
- Training & Knowledge Transfer: Deliver operator training on critical process steps or process changes; chip in to lessons-learned, playbooks, and guidelines across sites.
- Regulatory Contributions: Draft and review CMC sections (Module 3) response to agency question, support health authority and internal audits/inspections.
Technology Transfer & Process Validation
- Draft and review risk assessments and comparability study design
- Chip in to technology transfer packages (process descriptions, URS inputs, BOMs, risk assessments), implement process changes, coordinate execution of engineering runs and comparability/bridging studies, author technical reports
- Translate process characterization outputs from development into manufacturing controls, and draft sections of PPQ protocols/reports
- Provide on‑the‑floor technical support during scale‑up, engineering runs, PPQ batches, and commercial manufacturing campaigns (including off‑shift support when required).
Multi-functional Collaboration
- Position serves as primary interface between site Manufacturing, site Quality, site Supply Chain, and global functions of Process Development and CMC regulatory
- Support lifecycle management for cell therapy processes, including continuous improvement initiatives and post-approval changes
Required Qualifications
Minimum Education and experience:
B.S. with 8+ years of handson industry experience. M.S. with 4 years of handson industry experience, PhD in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field with 1+ years of industry experience
Technical Skills
- Strong technical and hands-on expertise in key cell therapy unit operations and common cell therapy processing equipment
- Demonstrated experience working in GMP environments, including batch record execution or review, deviations, and investigations.
- Proficiency with statistical analysis (including univariate, multi-variate analysis, control charts)
- Proven ability in accurate and thorough technical writing, paired with clear and concise verbal communication
- Strong data analysis, and problem‑solving skills.
Soft skills
- Excellent multi-functional communication and collaboration.
- Ability to translate complex data into clear decisions and regulatory-ready narratives.
- Excellent problem solving, multi-functional leadership, and communication under time-sensitive conditions.
Preferred Qualifications
- Experience with late‑stage clinical manufacturing support of cell therapy products
- Experience with process validation and commercial readiness of cell therapy products
Work Environment
- On-site in Rockville, MD
- Ability to travel ~15% to other manufacturing facilities
- On-call rotation during engineering/PPQ/critical campaigns
The annual base pay (or hourly rate of compensation) for this position ranges from $103,286.40 to $154,929.60. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
22-Sep-2026Closing Date
15-Oct-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
Senior Process Engineer, Manufacturing Sciences & Technology, Cell Therapy:
Location: AstraZeneca, Rockville, MD
Travel: Up to 15% domestic and international travel required
Position Summary
We are seeking an experienced Senior Process Engineer to join our Manufacturing Sciences & Technology (MS&T) function as a member of the site-based MS&T team at AstraZeneca’s Rockville, MD cell therapy manufacturing facility.
This position focuses on ensuring robust, compliant, and cost-effective manufacturing of clinical and commercial cell therapy products.
Responsibilities include leading on-the-floor / hands-on technical support, developing technical instructions, procedures, and operator training content, performing data analysis and process performance trending, leading complex deviation investigations, driving implementation of CAPAs and continuous improvement through change controls, and giving to validation and regulatory work. These responsibilities will be exercised through the scope of supporting technology transfers, clinical manufacturing, site readiness, process validation/PPQ, commercial manufacture readiness, and product lifecycle management activities.
The ideal candidate brings hands-on experience with cell therapy unit operations through previous experience in process development and/or manufacturing, as well as expertise in technology transfer. Experience with process validation and commercialization activities is desired. This position will report to Director, MS&T, Cell Therapy Development and Operations.
Key Responsibilities
Site manufacturing support
- Process Execution Support: Provide day-to-day technical support for cell therapy manufacturing, including on-the-floor support for critical campaigns (including occasional off-shift support where required)
- Operations Support: Represent Site MS&T function at site operational tier meetings, providing collaborative inputs that drive site activities
- Data trending and analysis: Maintain manufacturing data tracking system and control charts, perform trend analyses, identify signals, and drive timely signal-to-action with clear documentation and multi-functional alignment.
- Process performance monitoring: Conduct batch record review, deviation assessment, and data trending to ensure robustness of cell therapy manufacturing processes.
- Deviation/CAPA Support: Lead or co-lead technical investigations for deviations and process excursions, perform root cause analysis, develop and implement CAPAs with appropriate data.
- Continuous improvements: Identify, justify, and implement continuous improvements by shepherding changes through multi-functional change controls with appropriate risk assessments and comparability.
- Raw materials: Support qualification of critical materials (e.g., cytokines, viral vector, single-use assemblies) and assess impact of raw material changes, and supply to second-source strategies
- Automation: Partner with automation/digital manufacturing teams to implement electronic batch record improvements
- Documentation & GMP Compliance: Author and revise batch records, SOPs, and technical reports; protocols, summary reports, ensure alignment to cGMP/ATMP requirements and data integrity principles (ALCOA+).
- Training & Knowledge Transfer: Deliver operator training on critical process steps or process changes; chip in to lessons-learned, playbooks, and guidelines across sites.
- Regulatory Contributions: Draft and review CMC sections (Module 3) response to agency question, support health authority and internal audits/inspections.
Technology Transfer & Process Validation
- Draft and review risk assessments and comparability study design
- Chip in to technology transfer packages (process descriptions, URS inputs, BOMs, risk assessments), implement process changes, coordinate execution of engineering runs and comparability/bridging studies, author technical reports
- Translate process characterization outputs from development into manufacturing controls, and draft sections of PPQ protocols/reports
- Provide on‑the‑floor technical support during scale‑up, engineering runs, PPQ batches, and commercial manufacturing campaigns (including off‑shift support when required).
Multi-functional Collaboration
- Position serves as primary interface between site Manufacturing, site Quality, site Supply Chain, and global functions of Process Development and CMC regulatory
- Support lifecycle management for cell therapy processes, including continuous improvement initiatives and post-approval changes
Required Qualifications
Minimum Education and experience:
B.S. with 8+ years of handson industry experience. M.S. with 4 years of handson industry experience, PhD in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field with 1+ years of industry experience
Technical Skills
- Strong technical and hands-on expertise in key cell therapy unit operations and common cell therapy processing equipment
- Demonstrated experience working in GMP environments, including batch record execution or review, deviations, and investigations.
- Proficiency with statistical analysis (including univariate, multi-variate analysis, control charts)
- Proven ability in accurate and thorough technical writing, paired with clear and concise verbal communication
- Strong data analysis, and problem‑solving skills.
Soft skills
- Excellent multi-functional communication and collaboration.
- Ability to translate complex data into clear decisions and regulatory-ready narratives.
- Excellent problem solving, multi-functional leadership, and communication under time-sensitive conditions.
Preferred Qualifications
- Experience with late‑stage clinical manufacturing support of cell therapy products
- Experience with process validation and commercial readiness of cell therapy products
Work Environment
- On-site in Rockville, MD
- Ability to travel ~15% to other manufacturing facilities
- On-call rotation during engineering/PPQ/critical campaigns
The annual base pay (or hourly rate of compensation) for this position ranges from $103,286.40 to $154,929.60. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
22-Sep-2026Closing Date
15-Oct-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
See All 5 Manufacturing Process Engineer Jobs in Maryland
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Find JobsManufacturing Process Engineer Jobs by City in Maryland
Where Maryland roles are concentrated, by current openings.
Manufacturing Process Engineer Job Market in Maryland
A snapshot from current Maryland openings, updated as new roles post.
Who's Hiring
What Maryland Employers Look For
The qualifications that appear most often in manufacturing process engineer jobs across Maryland.
- Bachelor's degree in mechanical, industrial, or chemical engineering from an accredited program
- Hands-on experience with lean manufacturing, Six Sigma, or continuous improvement methodologies
- Proficiency with CAD software and process documentation tools such as AutoCAD or SolidWorks
- Familiarity with FDA or GMP regulations for roles in Maryland's biotech and pharmaceutical sectors
- Experience conducting root cause analysis and implementing corrective and preventive actions
- Strong understanding of statistical process control and production yield optimization techniques
Manufacturing Process Engineer Jobs in Maryland: Frequently Asked Questions
How do you become a manufacturing process engineer in Maryland?
Most manufacturing process engineer roles in Maryland require a bachelor's degree in mechanical, industrial, chemical, or manufacturing engineering from an ABET-accredited program. Maryland does not require a state-issued professional license for most private-sector manufacturing roles, though engineers in certain government-contract or public-works positions may pursue Professional Engineer licensure through the Maryland Board for Professional Engineers. Candidates targeting Maryland's biotech and defense sectors gain a strong edge with GMP training or a Six Sigma certification.
How much do manufacturing process engineers make in Maryland?
Manufacturing process engineers in Maryland earn a median of about $119,930 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $80,650 for the lowest 10% to over $168,100 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire manufacturing process engineers in Maryland?
Employers hiring manufacturing process engineers in Maryland right now include AstraZeneca, Northrop Grumman, and Tate Access Floors, based on current listings on Migrate Mate as of September 2026. Maryland's concentration of aerospace, defense, and life sciences manufacturers means openings appear consistently across the Baltimore metro and the D.C. suburban corridor year-round.
Which Maryland cities have the most manufacturing process engineer jobs?
Baltimore, Columbia, and Rockville have the most manufacturing process engineer openings in Maryland. Baltimore anchors the market through its deep base of food and beverage, biotech, and industrial manufacturers, while the D.C.-area suburbs draw heavily from defense and aerospace contractors headquartered along the I-270 and I-95 corridors.
Are there remote manufacturing process engineer jobs in Maryland?
Yes, but they're rare. Manufacturing process engineering is largely hands-on work tied to production floors, equipment, and physical validation, so most positions require on-site presence. About 100% of manufacturing process engineer openings tied to Maryland are remote or hybrid as of September 2026, and those tend to involve documentation, process development planning, or quality systems roles where direct floor access is not required daily.
How can I get hired as a manufacturing process engineer in Maryland with little or no experience?
The most realistic entry path is applying to co-op or new-graduate programs at Maryland's large defense and life sciences manufacturers, where employers like Northrop Grumman and Emergent BioSolutions regularly bring in engineers at the associate or process engineer I level. Pursuing a Six Sigma Green Belt or completing GMP coursework before applying makes a candidate noticeably more competitive. Lateral moves from quality technician, manufacturing technician, or production supervisor roles within Maryland plants are also a well-worn path into the engineer title.
Where can I find and apply to manufacturing process engineer jobs in Maryland?
You can find and apply to manufacturing process engineer jobs in Maryland on Migrate Mate, which lists current Maryland openings. Search the roles available, find the ones that match your background and target location, and apply directly to whichever positions fit.
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