Medical Laboratory Scientist Jobs in South Dakota

Medical Laboratory Scientist jobs in South Dakota are steadily in demand, concentrated in hospital systems, reference laboratories, and public health facilities, with openings at every level from new graduate to senior generalist and specialty lead. The most active hiring is in Sioux Falls, Rapid City, and Aberdeen, where employers like Sanford Health, Monument Health, and Avera Health consistently recruit across their networks. Blood banking, microbiology, and clinical chemistry are the specialties drawing the most consistent interest from South Dakota labs. See the openings below and apply to the ones that match your experience.

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Overview

Open roles12
Top employerSanford Health
Top citySioux Falls, SD
Cities hiring7
Work type75% On-site
Top industryHealthcare

Showing 5 of 12+ Medical Laboratory Scientist jobs

Monument Health
Medical Laboratory Technician / Medical Laboratory Scientist
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Monument Health
Added 2d ago
Medical Laboratory Technician / Medical Laboratory Scientist
Monument Health
Rapid City, South Dakota
Allied Health
Clinical Support
Healthcare Administration
Laboratory Science
Medical Assistant
$23 - $39/hr
On-Site
Associate's

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R&D Clinical Laboratory Scientist
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M
Added 6d ago
R&D Clinical Laboratory Scientist
Medgene Labs
Brookings, South Dakota
Administrative & Office Support
Customer Service
Customer Support
Hybrid
Bachelor's degree in animal science

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Medical Laboratory Scientist or Tech
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Added 1w ago
Medical Laboratory Scientist or Tech
MARSHALL COUNTY HEALTHCARE CENTER
Britton, South Dakota
Healthcare Administration
Patient Services & Wellbeing
Public Health

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Avera Health
Medical Laboratory Scientist
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Avera Health
Added 1w ago
Medical Laboratory Scientist
Avera Health
Sioux Falls, South Dakota
Healthcare Administration
Patient Services & Wellbeing
Public Health
$29.25 - $44/hr
Bachelor's degree in biological science
10,000+

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Sanford Health
Medical Laboratory Scientist/ Technician, Float
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Sanford Health
Added 2w ago
Medical Laboratory Scientist/ Technician, Float
Sanford Health
Sioux Falls, South Dakota
Clinical Support
Healthcare Administration
Patient Services & Wellbeing
$25 - $44/hr
Medical Laboratory Scientist Certification
10,000+

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See All 12 Medical Laboratory Scientist Jobs in South Dakota

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Medical Laboratory Scientist Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Sioux Falls
5 jobs
Vermillion
2 jobs
Britton
1 job
Yankton
1 job
Aberdeen
1 job
Brookings
1 job
Rapid City
1 job

Medical Laboratory Scientist Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

Sanford Health
Sanford Health6 open roles
Avera Health
Avera Health1 open role
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Medgene Labs1 open role

Top Industries Hiring

  • Healthcare & Medical Services

What South Dakota Employers Look For

The qualifications that appear most often in medical laboratory scientist jobs across South Dakota.

  • Active South Dakota clinical laboratory license or eligibility through ASCP or AMT certification
  • Bachelor's degree in medical laboratory science or a closely related clinical science
  • ASCP Board of Certification as MLS or equivalent nationally recognized credential
  • Demonstrated competency in high-complexity testing across core laboratory disciplines
  • Experience with laboratory information systems and electronic health record integration
  • Ability to work rotating shifts including evenings, weekends, and on-call coverage

Medical Laboratory Scientist Jobs in South Dakota: Frequently Asked Questions

How do you become a medical laboratory scientist in South Dakota?

To work as a medical laboratory scientist in South Dakota, you need a bachelor's degree in medical laboratory science or a related life science, followed by a clinical training program at an accredited institution. South Dakota does not maintain its own state licensure board for clinical laboratory scientists, so most employers require national certification through the ASCP Board of Certification as MLS or an equivalent credential from AMT. Completing a NAACLS-accredited program is the most direct path to meeting hiring requirements at Sanford Health, Avera Health, and Monument Health.

Which companies hire medical laboratory scientists in South Dakota?

South Dakota medical laboratory scientist roles are posted by Sanford Health, Avera Health, and Medgene Labs and others right now, based on current listings on Migrate Mate as of August 2026. Sanford Health and Avera Health are the two largest healthcare networks in the state and together account for a substantial share of ongoing laboratory staffing needs across Sioux Falls, Aberdeen, and surrounding communities.

Which South Dakota cities have the most medical laboratory scientist jobs?

Sioux Falls, Vermillion, and Britton see the most medical laboratory scientist openings in South Dakota. Sioux Falls generates the largest volume because it is home to the flagship campuses of both Sanford Health and Avera Health, while Rapid City's activity is anchored by Monument Health and its regional hospital network, and Aberdeen draws consistent openings from Avera St. Luke's and smaller regional facilities serving the northeastern part of the state.

Are there remote medical laboratory scientist jobs in South Dakota?

Yes, but they're rare. Medical laboratory scientist work is fundamentally hands-on, requiring physical presence to process specimens, operate analyzers, and perform high-complexity testing. About 25% of medical laboratory scientist openings tied to South Dakota are remote or hybrid as of August 2026, and those positions are typically limited to laboratory informatics, quality assurance review, or consulting roles that do not involve direct specimen handling.

How can I get hired as a medical laboratory scientist in South Dakota with little or no experience?

The most realistic entry path is completing a clinical rotation or internship embedded in an accredited MLS program, then applying directly to new-graduate positions at Sanford Health or Avera Health, both of which onboard new graduates and provide structured competency training. Candidates who have worked as phlebotomists, medical laboratory technicians, or histology technicians have a strong edge because that bench experience transfers directly. Holding an ASCP MLS certification at the time of application, even without post-graduation work history, significantly improves your standing for entry-level generalist openings in South Dakota.

Where can I find and apply to medical laboratory scientist jobs in South Dakota?

You can find and apply to medical laboratory scientist jobs in South Dakota on Migrate Mate, which lists current openings from employers across the state. Search for roles that match your credentials and experience level, then apply directly to the ones that fit. New listings are added regularly, so checking back frequently gives you the best view of what is currently available.

See All 12 Medical Laboratory Scientist Jobs in South Dakota

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