Medical Laboratory Scientist Jobs in South Dakota
Medical Laboratory Scientist jobs in South Dakota are steadily in demand, concentrated in hospital systems, reference laboratories, and public health facilities, with openings at every level from new graduate to senior generalist and specialty lead. The most active hiring is in Sioux Falls, Rapid City, and Aberdeen, where employers like Sanford Health, Monument Health, and Avera Health consistently recruit across their networks. Blood banking, microbiology, and clinical chemistry are the specialties drawing the most consistent interest from South Dakota labs. See the openings below and apply to the ones that match your experience.
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PRIMARY LOCATION
Rapid City, SD USA
DEPARTMENT
RCH North Medical Campus - Laboratory
SCHEDULED WEEKLY HOURS
36
STARTING PAY RATE RANGE
$23.71 - $39.53
Medical Laboratory Technician - SD $23.71-$29.64, Medical Laboratory Scientist - SD $31.62-$39.53
(Determined by the knowledge, skills, and experience of the applicant.)
JOB SUMMARY
UP TO A $10,000 SIGN ON BONUS AVAILABLE FOR QUALIFIED MLS CANDIDATES
UP TO A $7,500 SIGN ON BONUS AVAILABLE FOR QUALIFIED MLT CANDIDATES
It starts with heart. That is what you will do each day at Monument Health. As a Medical Laboratory MLT/MLS/MT at Monument Health, you will be valued as an essential team member providing compassionate patient focused care. You will discover a culture of teamwork, professionalism, mutual respect, and—most importantly—a life-changing career. You will make a difference. Every day.
As a Medical Laboratory MLT/MLS/MT, your focus will be to collect, prepare, and perform a variety of routine laboratory tests, with varying complexity. You will assist in department procedures, including quality assurance, proficiency testing, calibrations, and complete related laboratory duties and supervise new caregivers in the department. Each day you will be demonstrating a commitment to customer satisfaction, professionalism, and safety.
Our vision at Monument Health is to be one team, to listen, to be inclusive, and to show we care. To do the right thing. Every time. If you share this philosophy, we hope you’ll join us.
ESSENTIAL FUNCTIONS:
- Collects and prepares biological specimens for analyses using appropriate techniques and maintains the integrity of the specimen in relation to the test being performed.
- Determines acceptability of specimens within established guidelines, avoiding hemolysis, QNS, and wrong anticoagulant use.
- Performs all applicable testing with quality, speed, and accuracy according to established protocols and procedures. Evaluates specimen integrity and ascertains suitability for testing.
- Performs test analysis and reports test results in a timely manner meeting the expectations of physicians.
- Ensures prompt reporting of patient results for assigned department. Investigates problems involving collection, result reporting, and turn-around-time.
- Organizes department workload for maximum efficiency.
- Evaluates and interprets test results according to individual test specifications, performing necessary calculations; applies laboratory results to disease and/or patient therapy.
- Ensures initial calibration and standardization of equipment by applying criteria of acceptable functions and performance limits (i.e., precision, reproducibility, accuracy).
- Answers telephone promptly and courteously, identifying self and section. Demonstrates good judgment in directing phone calls/questions to appropriate section.
- Ensures smooth transition of duties within current shift and for oncoming shift by receiving pertinent information and conveying to other Healthcare personnel accurately and efficiently.
- Demonstrates the willingness and ability to instruct other staff and students.
- All other duties as assigned.
ADDITIONAL REQUIREMENTS
Required:
Education - Associates degree in Medical Laboratory Technology or Associates degree in a chemical, physical, or biological science. Or high school graduate or equivalent and have successfully completed an official military medical laboratory procedures course of at least 50 weeks duration and have held the military enlisted occupation specialty of medical laboratory specialist (laboratory technician)
Certification - Medical Lab Technician (MLT) - American Society for Clinical Pathology (ASCP), American Medical Technology (AMT), or Military Laboratory Specialist
Preferred:
Education - Bachelors degree in chemical, physical, or biologic Sciences or Clinical Laboratory Science
Certification - Medical Technologist (MT) or Medical Laboratory Scientist (MLS) Certification - American Society for Clinical Pathology (ASCP)/American Medical Technology (AMT) or Health and Human Services (HEW)
Experience - 1+ years of Laboratory Experience
Physical Requirements:
Medium work - Exerting up to 50 pounds of force occasionally, and/or up to 30 pounds of force frequently, and/or up to 10 pounds of force constantly to move objects. Possible exposure to blood, bodily fluids, or tissues.
JOB CATEGORY
Diagnostics
JOB FAMILY
Laboratory
SHIFT
Requires the ability to work assigned schedules and hours as determined by the department
EMPLOYEE TYPE
Regular
Make a difference. Every day.
Monument Health is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, or protected Veteran status.
See All 12 Medical Laboratory Scientist Jobs in South Dakota
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Find JobsMedical Laboratory Scientist Jobs by City in South Dakota
Where South Dakota roles are concentrated, by current openings.
Medical Laboratory Scientist Job Market in South Dakota
A snapshot from current South Dakota openings, updated as new roles post.
Who's Hiring


Top Industries Hiring
- Healthcare & Medical Services
What South Dakota Employers Look For
The qualifications that appear most often in medical laboratory scientist jobs across South Dakota.
- Active South Dakota clinical laboratory license or eligibility through ASCP or AMT certification
- Bachelor's degree in medical laboratory science or a closely related clinical science
- ASCP Board of Certification as MLS or equivalent nationally recognized credential
- Demonstrated competency in high-complexity testing across core laboratory disciplines
- Experience with laboratory information systems and electronic health record integration
- Ability to work rotating shifts including evenings, weekends, and on-call coverage
Medical Laboratory Scientist Jobs in South Dakota: Frequently Asked Questions
How do you become a medical laboratory scientist in South Dakota?
To work as a medical laboratory scientist in South Dakota, you need a bachelor's degree in medical laboratory science or a related life science, followed by a clinical training program at an accredited institution. South Dakota does not maintain its own state licensure board for clinical laboratory scientists, so most employers require national certification through the ASCP Board of Certification as MLS or an equivalent credential from AMT. Completing a NAACLS-accredited program is the most direct path to meeting hiring requirements at Sanford Health, Avera Health, and Monument Health.
Which companies hire medical laboratory scientists in South Dakota?
South Dakota medical laboratory scientist roles are posted by Sanford Health, Avera Health, and Medgene Labs and others right now, based on current listings on Migrate Mate as of August 2026. Sanford Health and Avera Health are the two largest healthcare networks in the state and together account for a substantial share of ongoing laboratory staffing needs across Sioux Falls, Aberdeen, and surrounding communities.
Which South Dakota cities have the most medical laboratory scientist jobs?
Sioux Falls, Vermillion, and Britton see the most medical laboratory scientist openings in South Dakota. Sioux Falls generates the largest volume because it is home to the flagship campuses of both Sanford Health and Avera Health, while Rapid City's activity is anchored by Monument Health and its regional hospital network, and Aberdeen draws consistent openings from Avera St. Luke's and smaller regional facilities serving the northeastern part of the state.
Are there remote medical laboratory scientist jobs in South Dakota?
Yes, but they're rare. Medical laboratory scientist work is fundamentally hands-on, requiring physical presence to process specimens, operate analyzers, and perform high-complexity testing. About 25% of medical laboratory scientist openings tied to South Dakota are remote or hybrid as of August 2026, and those positions are typically limited to laboratory informatics, quality assurance review, or consulting roles that do not involve direct specimen handling.
How can I get hired as a medical laboratory scientist in South Dakota with little or no experience?
The most realistic entry path is completing a clinical rotation or internship embedded in an accredited MLS program, then applying directly to new-graduate positions at Sanford Health or Avera Health, both of which onboard new graduates and provide structured competency training. Candidates who have worked as phlebotomists, medical laboratory technicians, or histology technicians have a strong edge because that bench experience transfers directly. Holding an ASCP MLS certification at the time of application, even without post-graduation work history, significantly improves your standing for entry-level generalist openings in South Dakota.
Where can I find and apply to medical laboratory scientist jobs in South Dakota?
You can find and apply to medical laboratory scientist jobs in South Dakota on Migrate Mate, which lists current openings from employers across the state. Search for roles that match your credentials and experience level, then apply directly to the ones that fit. New listings are added regularly, so checking back frequently gives you the best view of what is currently available.
See All 12 Medical Laboratory Scientist Jobs in South Dakota
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