Medical Laboratory Scientist Jobs in South Dakota

Medical Laboratory Scientist jobs in South Dakota are steadily in demand, concentrated in hospital systems, reference laboratories, and public health facilities, with openings at every level from new graduate to senior generalist and specialty lead. The most active hiring is in Sioux Falls, Rapid City, and Aberdeen, where employers like Sanford Health, Monument Health, and Avera Health consistently recruit across their networks. Blood banking, microbiology, and clinical chemistry are the specialties drawing the most consistent interest from South Dakota labs. See the openings below and apply to the ones that match your experience.

Find Jobs

Overview

Open roles13
Top employerSanford Health
Top citySioux Falls, SD
Cities hiring6
Work type100% On-site
Top industryHealthcare

Showing 5 of 13+ Medical Laboratory Scientist jobs

Medical Laboratory Scientist (MLS) or Medical Laboratory Technician (MLT)
We won't show you this job again
Added 4d ago
Medical Laboratory Scientist (MLS) or Medical Laboratory Technician (MLT)
Avera Health
Aberdeen, South Dakota
Healthcare Administration
Maintenance & Repair
Patient Services & Wellbeing
$24 - $44/hr
Associate's degree in Medical Laboratory Technology
10,000+

Have you applied for this role?

Medical Laboratory Scientist
We won't show you this job again
Added 5d ago
Medical Laboratory Scientist
Avera Health
Yankton, South Dakota
Healthcare Administration
Patient Services & Wellbeing
Public Health
$24 - $44/hr
Medical Laboratory Scientist Certification
10,000+

Have you applied for this role?

Medical Laboratory Scientist / Technician - Fulltime Days
We won't show you this job again
Added 5d ago
Medical Laboratory Scientist / Technician - Fulltime Days
Sanford Health
Sioux Falls, South Dakota
Healthcare Administration
Patient Services & Wellbeing
Public Health
$23.5 - $44/hr
Medical Laboratory Scientist Certification
10,000+

Have you applied for this role?

Medical Laboratory Technician/ Scientist
We won't show you this job again
Added 1w ago
Medical Laboratory Technician/ Scientist
Sanford Health
Sioux Falls, South Dakota
Healthcare Administration
Maintenance & Repair
Patient Services & Wellbeing
$25 - $44/hr
Bachelor's degree in biological science
10,000+

Have you applied for this role?

Medical Laboratory Scientist/ Technician- Straight Nights
We won't show you this job again
Added 1w ago
Medical Laboratory Scientist/ Technician- Straight Nights
Sanford Health
Sioux Falls, South Dakota
Biotech & Life Sciences
Clinical Support
Laboratory Science
$25 - $44/hr
Medical Laboratory Scientist Certification
10,000+

Have you applied for this role?

See All 13 Medical Laboratory Scientist Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

Find Jobs

Medical Laboratory Scientist Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Sioux Falls
6 jobs
Aberdeen
2 jobs
Vermillion
2 jobs
Britton
1 job
De Smet
1 job
Yankton
1 job

Medical Laboratory Scientist Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

Sanford Health9 open roles
Avera Health3 open roles
MARSHALL COUNTY HEALTHCARE CENTER1 open role

Top Industries Hiring

  • Healthcare & Medical Services

What South Dakota Employers Look For

The qualifications that appear most often in medical laboratory scientist jobs across South Dakota.

  • Active South Dakota clinical laboratory license or eligibility through ASCP or AMT certification
  • Bachelor's degree in medical laboratory science or a closely related clinical science
  • ASCP Board of Certification as MLS or equivalent nationally recognized credential
  • Demonstrated competency in high-complexity testing across core laboratory disciplines
  • Experience with laboratory information systems and electronic health record integration
  • Ability to work rotating shifts including evenings, weekends, and on-call coverage

Medical Laboratory Scientist Jobs in South Dakota: Frequently Asked Questions

How do you become a medical laboratory scientist in South Dakota?

To work as a medical laboratory scientist in South Dakota, you need a bachelor's degree in medical laboratory science or a related life science, followed by a clinical training program at an accredited institution. South Dakota does not maintain its own state licensure board for clinical laboratory scientists, so most employers require national certification through the ASCP Board of Certification as MLS or an equivalent credential from AMT. Completing a NAACLS-accredited program is the most direct path to meeting hiring requirements at Sanford Health, Avera Health, and Monument Health.

Which companies hire medical laboratory scientists in South Dakota?

South Dakota medical laboratory scientist roles are posted by Sanford Health, Avera Health, and MARSHALL COUNTY HEALTHCARE CENTER and others right now, based on current listings on Migrate Mate as of October 2026. Sanford Health and Avera Health are the two largest healthcare networks in the state and together account for a substantial share of ongoing laboratory staffing needs across Sioux Falls, Aberdeen, and surrounding communities.

Which South Dakota cities have the most medical laboratory scientist jobs?

Sioux Falls, Aberdeen, and Vermillion see the most medical laboratory scientist openings in South Dakota. Sioux Falls generates the largest volume because it is home to the flagship campuses of both Sanford Health and Avera Health, while Rapid City's activity is anchored by Monument Health and its regional hospital network, and Aberdeen draws consistent openings from Avera St. Luke's and smaller regional facilities serving the northeastern part of the state.

Are there remote medical laboratory scientist jobs in South Dakota?

Yes, but they're rare. Medical laboratory scientist work is fundamentally hands-on, requiring physical presence to process specimens, operate analyzers, and perform high-complexity testing. About 0% of medical laboratory scientist openings tied to South Dakota are remote or hybrid as of October 2026, and those positions are typically limited to laboratory informatics, quality assurance review, or consulting roles that do not involve direct specimen handling.

How can I get hired as a medical laboratory scientist in South Dakota with little or no experience?

The most realistic entry path is completing a clinical rotation or internship embedded in an accredited MLS program, then applying directly to new-graduate positions at Sanford Health or Avera Health, both of which onboard new graduates and provide structured competency training. Candidates who have worked as phlebotomists, medical laboratory technicians, or histology technicians have a strong edge because that bench experience transfers directly. Holding an ASCP MLS certification at the time of application, even without post-graduation work history, significantly improves your standing for entry-level generalist openings in South Dakota.

Where can I find and apply to medical laboratory scientist jobs in South Dakota?

You can find and apply to medical laboratory scientist jobs in South Dakota on Migrate Mate, which lists current openings from employers across the state. Search for roles that match your credentials and experience level, then apply directly to the ones that fit. New listings are added regularly, so checking back frequently gives you the best view of what is currently available.

See All 13 Medical Laboratory Scientist Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

Find Jobs